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DK3152332T3 - Fremgangsmåde til at analysere methylering - Google Patents

Fremgangsmåde til at analysere methylering Download PDF

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Publication number
DK3152332T3
DK3152332T3 DK15803413.2T DK15803413T DK3152332T3 DK 3152332 T3 DK3152332 T3 DK 3152332T3 DK 15803413 T DK15803413 T DK 15803413T DK 3152332 T3 DK3152332 T3 DK 3152332T3
Authority
DK
Denmark
Prior art keywords
analyzing methylation
methylation
analyzing
Prior art date
Application number
DK15803413.2T
Other languages
English (en)
Inventor
Susanne Pedersen
Rohan Baker
Original Assignee
Clinical Genomics Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2014902155A external-priority patent/AU2014902155A0/en
Application filed by Clinical Genomics Pty Ltd filed Critical Clinical Genomics Pty Ltd
Application granted granted Critical
Publication of DK3152332T3 publication Critical patent/DK3152332T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00Reactions characterised by treatment of reaction samples
    • C12Q2523/10Characterised by chemical treatment
    • C12Q2523/125Bisulfite(s)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10Modifications characterised by
    • C12Q2525/161Modifications characterised by incorporating target specific and non-target specific sites
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2561/00Nucleic acid detection characterised by assay method
    • C12Q2561/101Taqman
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • General Chemical & Material Sciences (AREA)
DK15803413.2T 2014-06-05 2015-06-01 Fremgangsmåde til at analysere methylering DK3152332T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2014902155A AU2014902155A0 (en) 2014-06-05 Method for Methylation Analysis
PCT/AU2015/050297 WO2015184498A2 (en) 2014-06-05 2015-06-01 Method for methylation analysis

Publications (1)

Publication Number Publication Date
DK3152332T3 true DK3152332T3 (da) 2021-03-29

Family

ID=54767512

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15803413.2T DK3152332T3 (da) 2014-06-05 2015-06-01 Fremgangsmåde til at analysere methylering

Country Status (15)

Country Link
US (1) US10590468B2 (da)
EP (1) EP3152332B1 (da)
JP (1) JP6810612B2 (da)
KR (1) KR20170012552A (da)
CN (1) CN106687600B (da)
AU (1) AU2015271641B2 (da)
BR (1) BR112016028442A2 (da)
CA (1) CA2950953A1 (da)
DK (1) DK3152332T3 (da)
IL (1) IL249331A0 (da)
MX (1) MX379058B (da)
PH (1) PH12016502411A1 (da)
SG (1) SG11201610113YA (da)
WO (1) WO2015184498A2 (da)
ZA (1) ZA201608367B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10125399B2 (en) 2014-10-30 2018-11-13 Personalis, Inc. Methods for using mosaicism in nucleic acids sampled distal to their origin
CA3060555A1 (en) 2017-04-19 2018-10-25 Singlera Genomics, Inc. Compositions and methods for library construction and sequence analysis
KR101959538B1 (ko) * 2017-05-29 2019-03-20 대한민국 CpG 아일랜드 예측 및 프라이머 제작을 위한 파이프라인 방법
CN111212918A (zh) * 2017-09-15 2020-05-29 临床基因组学私人有限公司 甲基化分析方法
WO2019163900A1 (ja) * 2018-02-22 2019-08-29 国立大学法人大阪大学 Rna修飾を利用した分析・診断法
WO2019223520A1 (zh) * 2018-05-22 2019-11-28 广州市康立明生物科技有限责任公司 肿瘤标志物、甲基化检测试剂、试剂盒及其应用
CN110511999A (zh) * 2018-05-22 2019-11-29 广州市康立明生物科技有限责任公司 肿瘤标志物、甲基化试剂、试剂盒及其应用
CN110512001A (zh) * 2018-05-22 2019-11-29 广州市康立明生物科技有限责任公司 肿瘤标志物、甲基化试剂、试剂盒及其应用
US20220251663A1 (en) * 2019-06-14 2022-08-11 Arizona Board Of Regents On Behalf Of The University Of Arizona Dna methylation biomarkers for cancer diagnosing and treatment
CN110527708A (zh) * 2019-07-11 2019-12-03 武汉伯远生物科技有限公司 一种区分dna中5-甲基化胞嘧啶和5-羟甲基化胞嘧啶的方法
CN110331142B (zh) * 2019-07-11 2021-12-21 广州康立明生物科技股份有限公司 一种多基因联合检测试剂
EP4055610A4 (en) 2019-11-05 2023-11-29 Personalis, Inc. ESTIMATION OF TUMOR PURITY FROM SINGLE SAMPLES
CN119685477A (zh) * 2020-03-20 2025-03-25 上海鹍远健康科技有限公司 筛查结直肠瘤的方法和试剂盒
CN116884482A (zh) * 2023-06-26 2023-10-13 平安科技(深圳)有限公司 m6A RNA甲基化位点预测方法、装置、设备及介质
CN118726590A (zh) * 2024-08-12 2024-10-01 中国医学科学院肿瘤医院 一种辅助检测食管癌淋巴结转移的甲基化生物标记物及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331393B1 (en) * 1999-05-14 2001-12-18 University Of Southern California Process for high-throughput DNA methylation analysis
EP1692264A2 (en) * 2003-10-28 2006-08-23 The Johns Hopkins University Quantitative multiplex methylation-specific pcr
WO2008135512A2 (en) * 2007-05-02 2008-11-13 Jerzy Paszkowski Dna amplification method
DK2847355T3 (da) * 2012-05-11 2019-10-14 Clinical Genomics Pty Ltd Diagnostisk genmarkørpanel for colorektal cancer
US10450609B2 (en) * 2012-05-22 2019-10-22 The Johns Hopkins University Quantitative multiplex methylation specific PCR method—cMethDNA, reagents, and its use
US20150141256A1 (en) 2013-07-29 2015-05-21 Roche Nimblegen, Inc. Compositions and methods for bisulfite converted sequence capture

Also Published As

Publication number Publication date
IL249331A0 (en) 2017-02-28
AU2015271641B2 (en) 2021-04-08
WO2015184498A2 (en) 2015-12-10
WO2015184498A3 (en) 2016-03-03
CN106687600B (zh) 2021-08-17
KR20170012552A (ko) 2017-02-02
ZA201608367B (en) 2019-05-29
BR112016028442A2 (pt) 2017-10-24
MX2016016062A (es) 2017-03-16
EP3152332A4 (en) 2018-01-10
CA2950953A1 (en) 2015-12-10
SG11201610113YA (en) 2017-01-27
US10590468B2 (en) 2020-03-17
AU2015271641A1 (en) 2016-12-22
JP6810612B2 (ja) 2021-01-06
MX379058B (es) 2025-03-10
PH12016502411A1 (en) 2017-02-27
JP2017517262A (ja) 2017-06-29
US20170145485A1 (en) 2017-05-25
EP3152332B1 (en) 2021-03-03
CN106687600A (zh) 2017-05-17
EP3152332A2 (en) 2017-04-12

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