DK307286A - Pyridinderivater, fremstilling deraf og farmaceutisk praeparat indeholdende forbindelserne - Google Patents
Pyridinderivater, fremstilling deraf og farmaceutisk praeparat indeholdende forbindelserne Download PDFInfo
- Publication number
- DK307286A DK307286A DK307286A DK307286A DK307286A DK 307286 A DK307286 A DK 307286A DK 307286 A DK307286 A DK 307286A DK 307286 A DK307286 A DK 307286A DK 307286 A DK307286 A DK 307286A
- Authority
- DK
- Denmark
- Prior art keywords
- preparing
- compounds
- pharmaceutical preparations
- sup
- sub
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical class C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 208000007882 Gastritis Diseases 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 230000001079 digestive effect Effects 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14639585 | 1985-07-02 | ||
| JP14639585 | 1985-07-02 | ||
| JP16045785 | 1985-07-19 | ||
| JP16045785 | 1985-07-19 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK307286D0 DK307286D0 (da) | 1986-06-27 |
| DK307286A true DK307286A (da) | 1987-01-03 |
| DK170819B1 DK170819B1 (da) | 1996-01-29 |
Family
ID=26477257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK307286A DK170819B1 (da) | 1985-07-02 | 1986-06-27 | Substituerede 2-[(3,4-dialkoxypyrid-2-yl)metyltio eller metylsulfinyl]benzimidazoler, fremgangsmåde til fremstilling deraf og farmaceutisk præparat indeholdende en sådan forbindelse |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4738975A (da) |
| EP (1) | EP0208452B1 (da) |
| JP (1) | JPH0674270B2 (da) |
| KR (1) | KR930010495B1 (da) |
| CN (1) | CN1018642B (da) |
| AT (1) | ATE67494T1 (da) |
| CA (1) | CA1339819C (da) |
| DE (1) | DE3681518D1 (da) |
| DK (1) | DK170819B1 (da) |
| HU (1) | HUT43589A (da) |
| IE (1) | IE59049B1 (da) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK171989B1 (da) * | 1987-08-04 | 1997-09-08 | Takeda Chemical Industries Ltd | Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler |
| ZA889194B (en) * | 1987-12-11 | 1989-08-30 | Byk Gulden Lomberg Chemisch Fa | Novel benzimidazole derivatives |
| WO1990003373A1 (fr) * | 1988-09-20 | 1990-04-05 | Hisamitsu Pharmaceutical Co., Inc. | NOUVEAUX DERIVES DE DIBENZ[b,e]OXEPINE |
| SE8804629D0 (sv) | 1988-12-22 | 1988-12-22 | Ab Haessle | New therapeutically active compounds |
| EG19302A (en) * | 1988-12-22 | 1994-11-30 | Haessle Ab | Compound with gastric acid inhibitory effect and process for its preparation |
| SE8804628D0 (sv) * | 1988-12-22 | 1988-12-22 | Ab Haessle | New compounds |
| GR1001241B (el) * | 1989-05-19 | 1993-06-30 | Byk Gulden Lomberg Chem Fab | Μεθοδος αλκυλιωσεως. |
| US4965269A (en) * | 1989-12-20 | 1990-10-23 | Ab Hassle | Therapeutically active chloro substituted benzimidazoles |
| US5049674A (en) * | 1989-12-20 | 1991-09-17 | Aktiebolaget Hassle | Therapeutically active fluoro substituted benzimidazoles |
| US5274099A (en) * | 1989-12-20 | 1993-12-28 | Aktiebolaget Hassle | Therapeutically active fluoro substituted benzimidazoles |
| SE9002206D0 (sv) | 1990-06-20 | 1990-06-20 | Haessle Ab | New compounds |
| ATE184602T1 (de) * | 1990-06-20 | 1999-10-15 | Astra Ab | Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung |
| AT394368B (de) * | 1990-08-07 | 1992-03-25 | Byk Gulden Lomberg Chem Fab | Verfahren zur herstellung von 3,4-dialkoxypyridinen |
| EP0481764B1 (en) * | 1990-10-17 | 2000-03-29 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, their production and use |
| US5298525A (en) * | 1992-11-23 | 1994-03-29 | University Technologies International, Inc. | Diabetes prevention and treatment |
| TW280770B (da) | 1993-10-15 | 1996-07-11 | Takeda Pharm Industry Co Ltd | |
| AU6551198A (en) * | 1997-05-30 | 1998-12-30 | Dr. Reddy's Research Foundation | Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them |
| PT1736144E (pt) | 1998-05-18 | 2016-02-10 | Takeda Pharmaceutical | Comprimidos de desintegração oral |
| DE19951960C2 (de) * | 1999-10-28 | 2002-06-27 | Gruenenthal Gmbh | Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate |
| US6544556B1 (en) | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
| US6884810B2 (en) * | 2001-09-18 | 2005-04-26 | Zeria Pharmaceutical Co., Ltd. | Benzimidazole derivatives |
| MXPA06002443A (es) * | 2003-09-03 | 2006-08-31 | Agi Therapeutics Ltd | Formulaciones inhibidoras de la bomba de protones y metodos para preparar y utilizar tales formulaciones. |
| EP1967211A4 (en) | 2005-12-28 | 2009-12-30 | Takeda Pharmaceutical | PROCESS FOR PRODUCING SOLID PREPARATION DISINTEGRATING IN ORAL CAVITY |
| ZA200904573B (en) | 2006-12-22 | 2010-09-29 | Ironwood Pharmaceuticals Inc | Compositions comprising bile acid sequestrants for treating esophageal disorders |
| US20130156720A1 (en) | 2010-08-27 | 2013-06-20 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
| JP6716255B2 (ja) | 2013-01-15 | 2020-07-01 | アイロンウッド ファーマシューティカルズ，インコーポレーテッドＩｒｏｎｗｏｏｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 胆汁酸捕捉剤の胃内滞留型徐放性経口剤形 |
| US20180015118A1 (en) | 2015-02-03 | 2018-01-18 | Ironwood Pharmaceuticals, Inc. | Methods of treating upper gastrointestinal disorders in ppi refractory gerd |
| WO2016174664A1 (en) | 2015-04-29 | 2016-11-03 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| WO2017145146A1 (en) | 2016-02-25 | 2017-08-31 | Dexcel Pharma Technologies Ltd. | Compositions comprising proton pump inhibitors |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
| IL66340A (en) * | 1981-08-13 | 1986-08-31 | Haessle Ab | Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation |
| US4472409A (en) * | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
| SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| HU195220B (en) * | 1983-05-03 | 1988-04-28 | Byk Gulden Lomberg Chem Fqb | Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them |
| IL76839A (en) * | 1984-10-31 | 1988-08-31 | Byk Gulden Lomberg Chem Fab | Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
-
1986
- 1986-06-18 US US06/875,702 patent/US4738975A/en not_active Expired - Lifetime
- 1986-06-23 AT AT86304803T patent/ATE67494T1/de not_active IP Right Cessation
- 1986-06-23 DE DE8686304803T patent/DE3681518D1/de not_active Expired - Fee Related
- 1986-06-23 EP EP19860304803 patent/EP0208452B1/en not_active Expired - Lifetime
- 1986-06-23 IE IE167586A patent/IE59049B1/en not_active IP Right Cessation
- 1986-06-26 KR KR1019860005148A patent/KR930010495B1/ko not_active Expired - Fee Related
- 1986-06-27 DK DK307286A patent/DK170819B1/da not_active IP Right Cessation
- 1986-06-30 CA CA000512760A patent/CA1339819C/en not_active Expired - Fee Related
- 1986-07-01 HU HU862745A patent/HUT43589A/hu not_active IP Right Cessation
- 1986-07-02 CN CN86104636A patent/CN1018642B/zh not_active Expired
- 1986-07-02 JP JP61156824A patent/JPH0674270B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0208452B1 (en) | 1991-09-18 |
| HUT43589A (en) | 1987-11-30 |
| EP0208452A2 (en) | 1987-01-14 |
| IE59049B1 (en) | 1993-12-15 |
| IE861675L (en) | 1987-01-02 |
| DK170819B1 (da) | 1996-01-29 |
| JPS62116576A (ja) | 1987-05-28 |
| CN1018642B (zh) | 1992-10-14 |
| KR930010495B1 (ko) | 1993-10-25 |
| DK307286D0 (da) | 1986-06-27 |
| CN86104636A (zh) | 1987-01-28 |
| US4738975A (en) | 1988-04-19 |
| JPH0674270B2 (ja) | 1994-09-21 |
| EP0208452A3 (en) | 1988-03-30 |
| CA1339819C (en) | 1998-04-14 |
| KR870001195A (ko) | 1987-03-12 |
| ATE67494T1 (de) | 1991-10-15 |
| DE3681518D1 (de) | 1991-10-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |
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