[go: up one dir, main page]

DK2766367T3 - 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidinderivater, deres fremstilling og deres anvendelse som antivirale aktive stoffer - Google Patents

4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidinderivater, deres fremstilling og deres anvendelse som antivirale aktive stoffer Download PDF

Info

Publication number
DK2766367T3
DK2766367T3 DK12775659.1T DK12775659T DK2766367T3 DK 2766367 T3 DK2766367 T3 DK 2766367T3 DK 12775659 T DK12775659 T DK 12775659T DK 2766367 T3 DK2766367 T3 DK 2766367T3
Authority
DK
Denmark
Prior art keywords
phenylpyrazolo
phenylamino
amino
preparation
active substances
Prior art date
Application number
DK12775659.1T
Other languages
English (en)
Inventor
Peter Wutzler
Michaela Schmidtke
Vadim Makarov
Original Assignee
Scandion Oncology As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE201110116373 external-priority patent/DE102011116373A1/de
Application filed by Scandion Oncology As filed Critical Scandion Oncology As
Application granted granted Critical
Publication of DK2766367T3 publication Critical patent/DK2766367T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK12775659.1T 2011-10-14 2012-10-15 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidinderivater, deres fremstilling og deres anvendelse som antivirale aktive stoffer DK2766367T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE201110116373 DE102011116373A1 (de) 2011-10-14 2011-10-14 Methode zur Herstellung von 4-Amino-3-arylamino-6-arylpyrazolo[3, 4-d]pyrimidinen
DE102011116384 2011-10-20
PCT/EP2012/070403 WO2013053942A1 (de) 2011-10-14 2012-10-15 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidin-derivate, deren herstellung und deren verwendung als antivirale wirkstoffe

Publications (1)

Publication Number Publication Date
DK2766367T3 true DK2766367T3 (da) 2022-08-01

Family

ID=47071252

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12775659.1T DK2766367T3 (da) 2011-10-14 2012-10-15 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidinderivater, deres fremstilling og deres anvendelse som antivirale aktive stoffer

Country Status (22)

Country Link
US (1) US9790225B2 (da)
EP (1) EP2766367B1 (da)
JP (1) JP6071012B2 (da)
KR (1) KR20140095467A (da)
CN (1) CN103946224A (da)
AU (1) AU2012322750B2 (da)
BR (1) BR112014008815B1 (da)
CA (1) CA2850439C (da)
DK (1) DK2766367T3 (da)
ES (1) ES2924828T3 (da)
HR (1) HRP20220928T1 (da)
HU (1) HUE059217T2 (da)
IL (1) IL231934A (da)
LT (1) LT2766367T (da)
MX (1) MX2014003987A (da)
PL (1) PL2766367T3 (da)
PT (1) PT2766367T (da)
RU (1) RU2014118953A (da)
SG (2) SG11201401351PA (da)
SI (1) SI2766367T1 (da)
WO (1) WO2013053942A1 (da)
ZA (1) ZA201402226B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2662822T3 (es) * 2015-03-04 2018-04-09 Scandion Oncology A/S Derivados de 4-amino-3-fenilamino-6-fenilpirazol[3,4-d]pirimidina para uso como inhibidores de la BCRP en tratamientos terapéuticos
KR102205570B1 (ko) 2018-09-12 2021-01-20 김홍기 뿌리식물 수경재배용 시트

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2965643A (en) 1960-12-20 Derivatives of pyrazolo
US3551428A (en) 1956-02-10 1970-12-29 Ciba Geigy Corp New 1- (or 2-) substituted 4-mercapto-pyrazolo(3,4-d)pyrimidines
DE3712735A1 (de) 1987-04-15 1988-11-10 Boehringer Mannheim Gmbh Neue pyrazolo(3,4-d)pyrimidine, verfahren zu ihrer herstellung und verwendung als arzneimittel
FI933303A7 (fi) 1991-01-23 1993-08-31 Gensia Inc Adenosiinikinaasi-inhibiittoreita
TW370529B (en) * 1992-12-17 1999-09-21 Pfizer Pyrazolopyrimidines
US5646152A (en) 1994-06-15 1997-07-08 Pfizer Inc. Methods of administering CRF antagonists
CZ27399A3 (cs) 1999-01-26 2000-08-16 Ústav Experimentální Botaniky Av Čr Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
DE102006029074A1 (de) 2006-06-22 2007-12-27 Friedrich-Schiller-Universität Jena 4-Amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidin-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung als antivirale Wirkstoffe

Also Published As

Publication number Publication date
SG10201602846TA (en) 2016-05-30
LT2766367T (lt) 2022-08-25
US20140296259A1 (en) 2014-10-02
ES2924828T3 (es) 2022-10-11
HUE059217T2 (hu) 2022-10-28
SG11201401351PA (en) 2014-08-28
EP2766367B1 (de) 2022-05-18
EP2766367A1 (de) 2014-08-20
IL231934A0 (en) 2014-05-28
PL2766367T3 (pl) 2022-08-22
IL231934A (en) 2017-03-30
CA2850439C (en) 2020-04-07
RU2014118953A (ru) 2015-11-20
CA2850439A1 (en) 2013-04-18
BR112014008815A2 (pt) 2017-04-25
PT2766367T (pt) 2022-08-12
KR20140095467A (ko) 2014-08-01
AU2012322750B2 (en) 2016-11-10
JP6071012B2 (ja) 2017-02-01
BR112014008815B1 (pt) 2021-01-12
WO2013053942A1 (de) 2013-04-18
MX2014003987A (es) 2014-09-22
NZ623573A (en) 2016-08-26
HRP20220928T1 (hr) 2022-10-28
AU2012322750A1 (en) 2014-04-24
CN103946224A (zh) 2014-07-23
SI2766367T1 (sl) 2022-10-28
JP2014528468A (ja) 2014-10-27
US9790225B2 (en) 2017-10-17
ZA201402226B (en) 2015-05-27

Similar Documents

Publication Publication Date Title
IL231592A0 (en) Pyrrolopyrimidine and purine derivatives
CO7010840A2 (es) Derivados de tieno [3,2-d]pirimidina que tienen actividad inhibidora por las quinasas de las proteínas
SMT201600155B (it) Pirazolo[i, 5-a]pirimidine e -triazine come agenti antivirali
EP2751112A4 (en) SUBSTITUTED PYRAZOLO [3,4-D] PYRIMIDINE AND ITS USE
IL229863A (en) The history of pyramidine and pyridine, their preparation and their pharmaceutical preparations
IL240877A0 (en) History of triazolo [5,4-d] pyrimidine, their preparation and pharmaceutical preparations containing them
ZA201204871B (en) Thiazolo[5,4-d]pyrimidines and their use as agrochemicals
HUE037064T2 (hu) Pirrolo[3,2-d]-pirimidin származékok vírusos fertõzések és egyéb betegségek kezelésére
PL2655375T3 (pl) Pochodne pirymidynonu, ich wytwarzanie i ich farmaceutyczne zastosowanie
IL231381A0 (en) History of aminopyrimidines, their preparation and pharmaceutical preparations containing them
ZA201007679B (en) Annelated n-heterocyclic sulfonamides with oxadiazolone headgroup,processes for their preparation and their use as pharmaceuticals
IL233808B (en) History of triazole[5,4-d]pyrimidine and drugs containing them
IL227404A0 (en) Pyrimidine history, their preparation and pharmaceutical preparations containing them
DK2736888T3 (da) 3-heteroaroylaminopropionsyrederivater og deres anvendelse som farmaceutika
SMT201500322B (it) Derivati di tieno[2,3-d]pirimidina e loro uso per trattare l'aritmia
DK2766367T3 (da) 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidinderivater, deres fremstilling og deres anvendelse som antivirale aktive stoffer
DK2310395T3 (da) 9-Substituerede 5-carboxyoxadiazinoquinolonderivater, deres fremstilling samt deres anvendelse som antibakterielle midler
HK1195303A (en) Pyrazoloquinolinone derivatives, preparation thereof and therapeutic use thereof
CO6801760A2 (es) Uso de las sales de 3-carboxi-n-etil-n,n-dimetilpropan-1-aminio en el tratamiento de enfermedad cardiovascular