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DK274580A - Fremgangsmaade til fremstilling af tripeptidamider - Google Patents

Fremgangsmaade til fremstilling af tripeptidamider

Info

Publication number
DK274580A
DK274580A DK274580A DK274580A DK274580A DK 274580 A DK274580 A DK 274580A DK 274580 A DK274580 A DK 274580A DK 274580 A DK274580 A DK 274580A DK 274580 A DK274580 A DK 274580A
Authority
DK
Denmark
Prior art keywords
tripeptidamides
procedure
preparation
Prior art date
Application number
DK274580A
Other languages
English (en)
Other versions
DK149610B (da
DK149610C (da
Inventor
L Kisfaludy
T Szirtes
L Balaspiri
E Palosi
L Szporny
A Sarkadi
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of DK274580A publication Critical patent/DK274580A/da
Publication of DK149610B publication Critical patent/DK149610B/da
Application granted granted Critical
Publication of DK149610C publication Critical patent/DK149610C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043Leu-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052Val-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • C07K5/06147Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK274580A 1979-06-28 1980-06-26 Analogifremgangsmaade til fremstilling af trh-analoge di- eller tripeptidamider eller terapeutisk acceptable komplekser eller salte deraf DK149610C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU79RI718A HU180926B (en) 1979-06-28 1979-06-28 Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem
HURI000718 1979-06-28

Publications (3)

Publication Number Publication Date
DK274580A true DK274580A (da) 1980-12-29
DK149610B DK149610B (da) 1986-08-11
DK149610C DK149610C (da) 1987-05-04

Family

ID=11001101

Family Applications (1)

Application Number Title Priority Date Filing Date
DK274580A DK149610C (da) 1979-06-28 1980-06-26 Analogifremgangsmaade til fremstilling af trh-analoge di- eller tripeptidamider eller terapeutisk acceptable komplekser eller salte deraf

Country Status (23)

Country Link
US (1) US4386073A (da)
JP (1) JPS568354A (da)
AT (1) AT380259B (da)
AU (1) AU538621B2 (da)
BE (1) BE884015A (da)
BG (1) BG60739B2 (da)
CA (1) CA1188296A (da)
CH (1) CH650519A5 (da)
CS (1) CS241028B2 (da)
DD (1) DD151745A5 (da)
DE (1) DE3024256A1 (da)
DK (1) DK149610C (da)
FI (1) FI73224C (da)
FR (1) FR2460291A1 (da)
GB (1) GB2058079B (da)
HU (1) HU180926B (da)
IL (1) IL60406A (da)
IT (1) IT1174678B (da)
NL (1) NL192575C (da)
PL (1) PL123822B1 (da)
SE (1) SE447389B (da)
SU (1) SU1085505A3 (da)
YU (1) YU43220B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU184481B (en) * 1981-10-02 1984-08-28 Richter Gedeon Vegyeszet Process for producing tripeptides for diminishing appetite
CA1256650A (en) * 1983-03-25 1989-06-27 Toshinari Tamura Process of producing 2-azetidinone-4-substituted compounds, and medicaments containing the compounds
GB2146026A (en) * 1983-09-07 1985-04-11 Tanabe Seiyaku Co Peptides and process for preparing the same
JPS60190795A (ja) * 1984-03-09 1985-09-28 Takeda Chem Ind Ltd ペプタイド
US4608365A (en) * 1984-03-30 1986-08-26 University Of Southern California Treatment of neurologic functions
US4719207A (en) * 1984-06-25 1988-01-12 Yamanouchi Pharmaceutical Co., Ltd. CNS active substituted azetidinone compounds
IL75641A (en) * 1984-07-10 1990-11-05 Tanabe Seiyaku Co 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it
IE58849B1 (en) * 1984-12-18 1993-11-17 Gruenenthal Chemie Use of dipeptide derivatives for the manufacture of medicaments for the treatment of patients with amyotrophic lateral sclerosis
JPS6222797A (ja) * 1985-07-19 1987-01-30 Tanabe Seiyaku Co Ltd 新規ペプタイド
IT1202426B (it) * 1987-01-26 1989-02-09 Poli Ind Chimica Spa Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono
JPH06104079B2 (ja) * 1988-07-14 1994-12-21 日東紡績株式会社 新規な酵素活性測定用基質
FR2649110B1 (fr) * 1989-06-29 1994-10-21 Adir Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE69118784T2 (de) * 1990-08-17 1996-09-19 Japan Tobacco Inc Neue Peptidderivate und deren pharmazeutischer Gebrauch
HU206374B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing pentapeptide and its salts specifically inhibiting proliferation of epidermic cells, as well as pharmaceutical compositions comprising same as active ingredient
IT1244548B (it) * 1991-02-06 1994-07-15 Poli Ind Chimica Spa Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche
US20020151502A1 (en) * 1997-10-09 2002-10-17 Albert Sattin Tri-peptides for neurological and neurobehavior applications
US20050233973A1 (en) * 1997-10-09 2005-10-20 Albert Sattin Tri-peptides for antidepressant applications
WO2002004016A1 (fr) * 2000-07-11 2002-01-17 Shionogi & Co., Ltd. Preparations enteriques contenant des peptides physiologiquement actifs
CN1283314C (zh) * 2000-08-31 2006-11-08 盐野义制药株式会社 抗帕金森氏病药
US8143369B2 (en) * 2009-06-02 2012-03-27 International Business Machines Corporation Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof
JP6847948B2 (ja) * 2016-07-14 2021-03-24 昭和電工株式会社 メラニン産生抑制剤、美白剤、線維芽細胞活性化剤、コラーゲン及び/又はエラスチン産生促進剤、及びシワ改善剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2343037A1 (de) * 1973-08-25 1975-03-06 Hoechst Ag Arzneimittel mit antidepressiver wirkung
US3959248A (en) * 1974-04-03 1976-05-25 Merck & Co., Inc. Analogs of thyrotropin-releasing hormone
NL183764C (nl) * 1974-10-16 1989-01-16 Gruenenthal Gmbh Werkwijze voor de bereiding van een geneesmiddel met psychotrope of neurotrope werking en werkwijze voor de bereiding van een histidylprolineamide-derivaat.
DE2449167C2 (de) * 1974-10-16 1984-05-24 Grünenthal GmbH, 5190 Stolberg N-Acyl-L-histidyl-L-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
JPS5944308B2 (ja) * 1976-03-23 1984-10-29 武田薬品工業株式会社 ペプタイド

Also Published As

Publication number Publication date
PL225269A1 (da) 1981-05-08
BG60739B2 (bg) 1996-01-31
YU169580A (en) 1984-04-30
DE3024256C2 (da) 1991-01-24
FI802058A7 (fi) 1980-12-29
DE3024256A1 (de) 1981-01-08
JPH0159278B2 (da) 1989-12-15
FR2460291B1 (da) 1984-11-23
IL60406A (en) 1984-10-31
AT380259B (de) 1986-05-12
NL8003766A (nl) 1980-12-30
GB2058079A (en) 1981-04-08
YU43220B (en) 1989-06-30
SE447389B (sv) 1986-11-10
ATA334780A (de) 1985-09-15
NL192575B (nl) 1997-06-02
IT1174678B (it) 1987-07-01
HU180926B (en) 1983-05-30
DK149610B (da) 1986-08-11
DD151745A5 (de) 1981-11-04
US4386073A (en) 1983-05-31
BE884015A (fr) 1980-12-29
IL60406A0 (en) 1980-09-16
PL123822B1 (en) 1982-11-30
SE8004745L (sv) 1980-12-29
FI73224B (fi) 1987-05-29
JPS568354A (en) 1981-01-28
CS241028B2 (en) 1986-03-13
IT8023097A0 (it) 1980-06-26
AU538621B2 (en) 1984-08-23
CA1188296A (en) 1985-06-04
GB2058079B (en) 1983-03-02
CS458380A2 (en) 1985-06-13
FR2460291A1 (fr) 1981-01-23
DK149610C (da) 1987-05-04
AU5972080A (en) 1981-01-08
CH650519A5 (de) 1985-07-31
FI73224C (fi) 1987-09-10
SU1085505A3 (ru) 1984-04-07
NL192575C (nl) 1997-10-03

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Legal Events

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PBP Patent lapsed