DK2038430T3 - Toll-Like-Receptor-4-dysfunktion og de biologiske anvendelser deraf - Google Patents
Toll-Like-Receptor-4-dysfunktion og de biologiske anvendelser derafInfo
- Publication number
- DK2038430T3 DK2038430T3 DK07819905.6T DK07819905T DK2038430T3 DK 2038430 T3 DK2038430 T3 DK 2038430T3 DK 07819905 T DK07819905 T DK 07819905T DK 2038430 T3 DK2038430 T3 DK 2038430T3
- Authority
- DK
- Denmark
- Prior art keywords
- tlr4
- toll
- receptor
- subject
- mutated
- Prior art date
Links
- 102000008233 Toll-Like Receptor 4 Human genes 0.000 title abstract 9
- 108010060804 Toll-Like Receptor 4 Proteins 0.000 title abstract 9
- 230000004064 dysfunction Effects 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06291164A EP1881080A1 (en) | 2006-07-18 | 2006-07-18 | Toll like receptor 4 dysfunction and the biological applications thereof |
| PCT/EP2007/057402 WO2008009693A1 (en) | 2006-07-18 | 2007-07-17 | Toll like receptor 4 dysfunction and the biological applications thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2038430T3 true DK2038430T3 (da) | 2012-01-30 |
Family
ID=37402663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07819905.6T DK2038430T3 (da) | 2006-07-18 | 2007-07-17 | Toll-Like-Receptor-4-dysfunktion og de biologiske anvendelser deraf |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8557517B2 (da) |
| EP (2) | EP1881080A1 (da) |
| JP (1) | JP2009543570A (da) |
| AT (1) | ATE537271T1 (da) |
| DK (1) | DK2038430T3 (da) |
| ES (1) | ES2378847T3 (da) |
| WO (1) | WO2008009693A1 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008317261B2 (en) | 2007-10-26 | 2015-04-09 | Dynavax Technologies Corporation | Methods and compositions for inhibition of immune responses and autoimmunity |
| EP2316032A1 (en) | 2008-08-20 | 2011-05-04 | INSERM - Institut National de la Santé et de la Recherche Médicale | Methods for predicting the response to anti-cancer treatment with an agonist of tlr7 or an agonist of tlr8 |
| WO2011159958A2 (en) * | 2010-06-16 | 2011-12-22 | Dynavax Technologies Corporation | Methods of treatment using tlr7 and/or tlr9 inhibitors |
| JP6000287B2 (ja) * | 2011-03-03 | 2016-09-28 | クォーク ファーマシューティカルズ インコーポレーティッドＱｕａｒｋ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | 肺疾患および損傷を治療するための組成物および方法 |
| WO2012135824A2 (en) * | 2011-03-31 | 2012-10-04 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Method of screening for colon cancer using biomarkers |
| WO2012139945A1 (en) * | 2011-04-14 | 2012-10-18 | Universidad De Navarra | Method for predicting survival in cancer patients |
| WO2013122545A1 (en) * | 2012-02-14 | 2013-08-22 | National University Of Singapore | Synergistic combinations for use in treating cancer |
| ES2891081T3 (es) * | 2013-08-27 | 2022-01-26 | Deutsches Krebsforsch | Modificadores de la respuesta de células T citotóxicas |
| GB2544198B (en) | 2014-05-21 | 2021-01-13 | Integenx Inc | Fluidic cartridge with valve mechanism |
| US10690627B2 (en) | 2014-10-22 | 2020-06-23 | IntegenX, Inc. | Systems and methods for sample preparation, processing and analysis |
| US12044680B2 (en) | 2016-05-13 | 2024-07-23 | Mbl International Corp. | Peptide exchange system and method |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63503308A (ja) * | 1986-05-09 | 1988-12-02 | スローン‐ケツテリング・インステイテユート・フオー・キヤンサー・リサーチ | 抗腫瘍療法のためのリポ多糖体及び天然因子の組成物及び治療方法 |
| US6982252B2 (en) | 2000-12-04 | 2006-01-03 | Memorial Sloan-Kettering Cancer Center | Inhibition of vacuolar proton ATPase activity and/or the modulation of acidic organelle function sensitizes cells to radiation, chemotherapy and biological agents |
| US20030165479A1 (en) * | 2001-03-19 | 2003-09-04 | Velleca Mark A. | Methods for isolating proteins expressed by dendritic cells |
| US7195868B2 (en) * | 2001-04-18 | 2007-03-27 | Millennium Pharmaceuticals, Inc. | Compositions and methods for the identification, assessment, prevention, and therapy of human cancers |
| GB0226251D0 (en) * | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
| US6916627B2 (en) | 2002-11-27 | 2005-07-12 | St. Jude Children's Research Hospital | ATM kinase compositions and methods |
| WO2005040208A2 (en) * | 2003-10-21 | 2005-05-06 | Androclus Therapeutics, Soa | Peptides derived from heat shock proteins binding toll-like receptors 2 and 4 and their use |
| AU2005269733B2 (en) * | 2004-07-20 | 2008-10-30 | Schering Corporation | Induction of apoptosis in Toll-like receptor expressing tumor cells |
| WO2006054129A1 (en) * | 2004-11-19 | 2006-05-26 | Institut Gustave Roussy | Improved treatment of cancer by double-stranded rna |
-
2006
- 2006-07-18 EP EP06291164A patent/EP1881080A1/en not_active Withdrawn
-
2007
- 2007-07-17 EP EP07819905A patent/EP2038430B1/en not_active Not-in-force
- 2007-07-17 US US12/373,789 patent/US8557517B2/en not_active Expired - Fee Related
- 2007-07-17 WO PCT/EP2007/057402 patent/WO2008009693A1/en not_active Ceased
- 2007-07-17 DK DK07819905.6T patent/DK2038430T3/da active
- 2007-07-17 ES ES07819905T patent/ES2378847T3/es active Active
- 2007-07-17 AT AT07819905T patent/ATE537271T1/de active
- 2007-07-17 JP JP2009519976A patent/JP2009543570A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2038430B1 (en) | 2011-12-14 |
| ES2378847T3 (es) | 2012-04-18 |
| JP2009543570A (ja) | 2009-12-10 |
| EP2038430A1 (en) | 2009-03-25 |
| US8557517B2 (en) | 2013-10-15 |
| US20100004161A1 (en) | 2010-01-07 |
| ATE537271T1 (de) | 2011-12-15 |
| EP1881080A1 (en) | 2008-01-23 |
| WO2008009693A1 (en) | 2008-01-24 |
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