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DK186189A - Phosphonoalkylpurinderivater samt anvendelsen heraf - Google Patents

Phosphonoalkylpurinderivater samt anvendelsen heraf

Info

Publication number
DK186189A
DK186189A DK186189A DK186189A DK186189A DK 186189 A DK186189 A DK 186189A DK 186189 A DK186189 A DK 186189A DK 186189 A DK186189 A DK 186189A DK 186189 A DK186189 A DK 186189A
Authority
DK
Denmark
Prior art keywords
phosphonoalkyl
purine derivatives
purine
derivatives
phosphonoalkyl purine
Prior art date
Application number
DK186189A
Other languages
English (en)
Other versions
DK186189D0 (da
Inventor
Serge Halazy
Charles Danzin
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK186189D0 publication Critical patent/DK186189D0/da
Publication of DK186189A publication Critical patent/DK186189A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK186189A 1988-04-19 1989-04-18 Phosphonoalkylpurinderivater samt anvendelsen heraf DK186189A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88400948A EP0338168A1 (en) 1988-04-19 1988-04-19 Phosphonoalkylpurine derivatives

Publications (2)

Publication Number Publication Date
DK186189D0 DK186189D0 (da) 1989-04-18
DK186189A true DK186189A (da) 1989-10-20

Family

ID=8200380

Family Applications (1)

Application Number Title Priority Date Filing Date
DK186189A DK186189A (da) 1988-04-19 1989-04-18 Phosphonoalkylpurinderivater samt anvendelsen heraf

Country Status (19)

Country Link
US (1) US4988680A (da)
EP (1) EP0338168A1 (da)
JP (1) JP2756579B2 (da)
KR (1) KR0139534B1 (da)
CN (1) CN1037342A (da)
AU (1) AU613478B2 (da)
CA (1) CA1341027C (da)
DE (1) DE68911192T2 (da)
DK (1) DK186189A (da)
ES (1) ES2062056T3 (da)
FI (1) FI891842A7 (da)
HU (1) HU204280B (da)
IE (1) IE891247L (da)
IL (1) IL90002A0 (da)
NO (1) NO891588L (da)
NZ (1) NZ228749A (da)
PH (1) PH27602A (da)
PT (1) PT90301B (da)
ZA (1) ZA892723B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0405748A1 (en) * 1989-05-30 1991-01-02 Beecham Group p.l.c. Phosphonoderivative of purine with antiviral activity
CZ285420B6 (cs) * 1990-04-24 1999-08-11 Ústav Organické Chemie A Biochemie Avčr N-(3-Fluor-2-fosfonylmethoxypropyl)deriváty purinových a pyrimidinových heterocyklických bazí, způsoby jejich přípravy a použití
EP0465297B1 (en) * 1990-07-04 1996-01-31 Merrell Dow Pharmaceuticals Inc. 9-Purinyl phosphonic acid derivatives
US5208221A (en) * 1990-11-29 1993-05-04 Bristol-Myers Squibb Company Antiviral (phosphonomethoxy) methoxy purine/pyrimidine derivatives
US5494912A (en) * 1991-06-26 1996-02-27 Merrell Pharmaceuticals Inc. 9-purinyl phosphonic acid derivitives for treating gout
US7371852B2 (en) * 2003-01-22 2008-05-13 Serenex, Inc. Alkyl-linked nucleotide compositions
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
MX2012002368A (es) * 2009-08-27 2012-07-25 Epiphany Biosciences Inc Novedosos fosfonatos de nucleosido y analogos.
US9011817B2 (en) * 2009-09-03 2015-04-21 The Board Of Trustees Of The Leland Stanford Junior University Compounds and methods of making compounds
CN112110784B (zh) * 2020-09-02 2022-03-15 天津科技大学 一种新型高含水量造雾剂

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
EP0272446B1 (en) * 1983-05-24 1992-11-11 Sri International Novel antiviral agents
CA1288098C (en) * 1984-08-24 1991-08-27 Richard L. Tolman 4-(guanin-9-yl)butanals and their 3-oxa, 3-thia and 2-ene derivatives having antiviral and antitumor activity
US4695654A (en) * 1985-08-21 1987-09-22 Merrell Dow Pharmaceuticals Inc. Gem-dihalo-1,8-diamino-4-aza-octanes
US4719313A (en) * 1985-08-21 1988-01-12 Merrell Dow Pharmaceuticals Inc. Gem-dihalo and tetrahalo-1,12-diamino-4,9-diaza-dodecanes
US4730006A (en) * 1986-01-27 1988-03-08 Merrell Dow Pharmaceuticals Inc. Derivatives of 2,6-diamino-3-haloheptanedioic acid
IL84477A (en) * 1986-11-18 1995-12-08 Bristol Myers Squibb Co History of Phosphonomethoxyalkylene Purinopyrimidine and Pharmaceutical Preparations Containing Them

Also Published As

Publication number Publication date
HU204280B (en) 1991-12-30
IL90002A0 (en) 1989-12-15
FI891842A7 (fi) 1989-10-20
AU613478B2 (en) 1991-08-01
US4988680A (en) 1991-01-29
JPH026497A (ja) 1990-01-10
DE68911192D1 (de) 1994-01-20
ZA892723B (en) 1989-12-27
KR890016059A (ko) 1989-11-28
PT90301B (pt) 1994-09-30
NZ228749A (en) 1991-05-28
NO891588D0 (no) 1989-04-18
PT90301A (pt) 1989-11-10
FI891842A0 (fi) 1989-04-18
PH27602A (en) 1993-08-31
NO891588L (no) 1989-10-20
ES2062056T3 (es) 1994-12-16
DE68911192T2 (de) 1994-05-05
AU3315889A (en) 1989-10-26
DK186189D0 (da) 1989-04-18
EP0338168A1 (en) 1989-10-25
JP2756579B2 (ja) 1998-05-25
KR0139534B1 (ko) 1998-06-15
CA1341027C (en) 2000-06-13
CN1037342A (zh) 1989-11-22
IE891247L (en) 1989-10-19

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