DK17983D0 - Fremgangsmade til fremstilling af 6-substituerede s-triazol(3,4-a)-ftalazin-derivater - Google Patents

Fremgangsmade til fremstilling af 6-substituerede s-triazol(3,4-a)-ftalazin-derivater

Info

Publication number: DK17983D0
Authority: DK; Denmark
Prior art keywords: preparation; triazol; substituted; procedure; phthalazine derivatives
Prior art date: 1982-01-18

Application number

DK0179/83A

Other languages

English (en)

Other versions

DK17983A (da

DK163145B (da

DK163145C (da

Inventor

Emilio Occelli

Domenico Barone

Giorgio Tarzia

Adele Giunta

Original Assignee

Lepetit Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-01-18

Filing date

1983-01-18

Publication date

1983-01-18

1983-01-18 Application filed by Lepetit Spa filed Critical Lepetit Spa

1983-01-18 Publication of DK17983D0 publication Critical patent/DK17983D0/da

1983-07-19 Publication of DK17983A publication Critical patent/DK17983A/da

1992-01-27 Publication of DK163145B publication Critical patent/DK163145B/da

1992-06-22 Application granted granted Critical

1992-06-22 Publication of DK163145C publication Critical patent/DK163145C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Anesthesiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK017983A 1982-01-18 1983-01-18 Analogifremgangsmaade til fremstilling af 6-substituerede s-triazoloe3,4-aaaftalazin-derivater DK163145C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8201273		1982-01-18
GB8201273		1982-01-18

Publications (4)

Publication Number	Publication Date
DK17983D0 true DK17983D0 (da)	1983-01-18
DK17983A DK17983A (da)	1983-07-19
DK163145B DK163145B (da)	1992-01-27
DK163145C DK163145C (da)	1992-06-22

Family

ID=10527683

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK017983A DK163145C (da)	1982-01-18	1983-01-18	Analogifremgangsmaade til fremstilling af 6-substituerede s-triazoloe3,4-aaaftalazin-derivater

Country Status (20)

Country	Link
US (1)	US4788186A (da)
EP (1)	EP0085840B1 (da)
JP (1)	JPS58124786A (da)
KR (1)	KR890000184B1 (da)
AT (1)	ATE22562T1 (da)
AU (1)	AU564026B2 (da)
CA (1)	CA1214168A (da)
DE (1)	DE3366494D1 (da)
DK (1)	DK163145C (da)
ES (1)	ES531458A0 (da)
FI (1)	FI81350C (da)
GR (1)	GR78442B (da)
HU (1)	HU193033B (da)
IE (1)	IE55032B1 (da)
IL (1)	IL67697A (da)
NO (1)	NO161674C (da)
NZ (1)	NZ203021A (da)
PH (1)	PH21834A (da)
PT (1)	PT76107A (da)
ZA (1)	ZA83224B (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1194310B (it) *	1983-07-12	1988-09-14	Lepetit Spa	Derivati triazolo (3,4-a) ftalazinici 3,6-disostituiti
CA2260900A1 (en)	1996-07-25	1998-02-05	Merck Sharp & Dohme Limited	Substituted triazolo pyridazine derivatives as inverse agonists of the gabaa.alpha.5 receptor subtype
BR9710729A (pt) *	1996-07-25	1999-08-17	Merck Sharp & Dohme	Composto composi-Æo farmac-utica utiliza-Æo de um composto e processo para o tratamento e/ou a preven-Æo da ansiedade e de convuls{es para a triagem de compostos ansioliticos nÆo-sedativos e para a prepara-Æo de um composto
JP4672820B2 (ja) *	1997-05-08	2011-04-20	メルクシャープエンドドームリミテッド	ＧＡＢＡα５リガンドとしての置換１，２，４−トリアゾロ［３，４−ａ］フタラジン誘導体
ES2137113B1 (es) *	1997-07-29	2000-09-16	Almirall Prodesfarma Sa	Nuevos derivados de triazolo-piridazinas heterociclicos.
GB9715977D0 (en) *	1997-07-29	1997-10-01	Merck Sharp & Dohme	Therapeutic agents
GB9726699D0 (en) *	1997-12-18	1998-02-18	Merck Sharp & Dohme	Therapeutic use
GB9726702D0 (en) *	1997-12-18	1998-02-18	Merck Sharp & Dohme	Therapeutic use
GB9723999D0 (en)	1997-11-13	1998-01-14	Merck Sharp & Dohme	Therapeutic use
GB9726701D0 (en) *	1997-12-18	1998-02-18	Merck Sharp & Dohme	Therapeutic use
AU1041599A (en) *	1997-11-13	1999-06-07	Jose Luis Castro Pineiro	Therapeutic uses of triazolo-pyridazine derivatives
US6110915A (en) *	1997-12-18	2000-08-29	Merck & Co., Inc.	Antiemetic use of triazolo-pyridazine derivatives
JP2002509150A (ja) *	1998-01-14	2002-03-26	メルクシャープエンドドームリミテッド	Ｇａｂａ受容体のリガンドとしてのトリアゾロピリダジン誘導体
GB9801210D0 (en) *	1998-01-21	1998-03-18	Merck Sharp & Dohme	Therapeutic agents
GB9801234D0 (en) *	1998-01-21	1998-03-18	Merck Sharp & Dohme	Therapeutic agents
GB9801208D0 (en)	1998-01-21	1998-03-18	Merck Sharp & Dohme	Therapeutic agents
SK10922000A3 (sk)	1998-01-21	2001-03-12	Merck Sharp & Dohme Limited	Triazolopyridazínové deriváty, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie
GB9801202D0 (en)	1998-01-21	1998-03-18	Merck Sharp & Dohme	Therapeutic agents
GB9801397D0 (en) *	1998-01-22	1998-03-18	Merck Sharp & Dohme	Therapeutic agents
GB9801538D0 (en)	1998-01-23	1998-03-25	Merck Sharp & Dohme	Pharmaceutical product
TR200002469T2 (tr) *	1998-02-25	2000-12-21	Merck Sharp & Dohme Limited	İkameli 1,2,4-triazol [3,4-a]piridazin.
IL137117A0 (en)	1998-02-25	2001-06-14	Merck Sharp & Dohme	Substituted 1,2,4-triazolo [3,4-a] pyridazine
GB9824897D0 (en)	1998-11-12	1999-01-06	Merck Sharp & Dohme	Therapeutic compounds
AU1816900A (en)	1998-11-12	2000-05-29	Merck & Co., Inc.	Therapeutic polymorphs of a gaba-a alpha-5 inverse agonist and pamoate formulations of the same
GB9929569D0 (en) *	1999-12-14	2000-02-09	Merck Sharp & Dohme	Therapeutic agents
GB0028583D0 (en)	2000-11-23	2001-01-10	Merck Sharp & Dohme	Therapeutic compounds
EP1379250A2 (en) *	2001-04-10	2004-01-14	Merck & Co., Inc.	A method of treating cancer
WO2002083140A1 (en) *	2001-04-10	2002-10-24	Merck & Co., Inc.	Inhibitors of akt activity
US20060142178A1 (en) *	2002-04-08	2006-06-29	Barnett Stanley F	Method of treating cancer
US20050054647A1 (en) *	2002-12-27	2005-03-10	Detlev Schuppan	New pharmaceutical combination
CN101133057B (zh) *	2004-09-02	2011-03-09	尼科梅德有限责任公司	三唑并酞嗪化合物
CA2591991C (en)	2005-01-05	2013-11-19	Altana Pharma Ag	Triazolophthalazines
JP5240899B2 (ja) *	2005-01-05	2013-07-17	タケダゲゼルシャフトミットベシュレンクテルハフツング	トリアゾロフタラジン
PH12012501361A1 (en)	2009-12-31	2012-10-22	Centro Nac De Investigaciones Oncologicas Cnio	Tricyclic compounds for use as kinase inhibitors
CN103694244B (zh) *	2014-01-09	2016-03-30	郑州大学	3,6位取代-1,2,4-三氮唑并[3,4-a]酞嗪类化合物及其制备和用途
CN104016986B (zh) *	2014-03-13	2016-02-03	郑州大学	3-取代-6-(1-取代哌嗪基)-1,2,4-三氮唑并[3,4-a]酞嗪类化合物、其制备方法和用途
EP4279074A1 (en) *	2022-05-19	2023-11-22	Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin	Azolo compounds for treatment of fibrotic diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2484029A (en) *	1945-12-21	1949-10-11	Ciba Pharm Prod Inc	Hydrazine derivatives of pyridazine compounds
GB629177A (en) *	1945-12-21	1949-09-14	Ciba Ltd	Manufacture of new hydrazine compounds and derivatives thereof
JPS5132598A (en) *	1974-09-13	1976-03-19	Eisai Co Ltd	Toriazoro * 3 44 ee * futarajinjudotai no goseiho
JPS603080B2 (ja) *	1976-08-10	1985-01-25	三菱化学株式会社	Ｓ―トリアゾロ〔３，４ ―α〕〔５，６，７，８〕テトラヒドロフタラジン類
GR70309B (da) *	1979-10-29	1982-09-08	Dow Chemical Co

1983
- 1983-01-12 PH PH28380A patent/PH21834A/en unknown
- 1983-01-12 FI FI830100A patent/FI81350C/fi not_active IP Right Cessation
- 1983-01-13 NZ NZ203021A patent/NZ203021A/en unknown
- 1983-01-13 CA CA000419398A patent/CA1214168A/en not_active Expired
- 1983-01-13 DE DE8383100232T patent/DE3366494D1/de not_active Expired
- 1983-01-13 EP EP83100232A patent/EP0085840B1/en not_active Expired
- 1983-01-13 AT AT83100232T patent/ATE22562T1/de not_active IP Right Cessation
- 1983-01-13 GR GR70257A patent/GR78442B/el unknown
- 1983-01-13 ZA ZA83224A patent/ZA83224B/xx unknown
- 1983-01-14 NO NO830110A patent/NO161674C/no unknown
- 1983-01-17 HU HU83141A patent/HU193033B/hu not_active IP Right Cessation
- 1983-01-17 IL IL67697A patent/IL67697A/xx unknown
- 1983-01-17 IE IE82/83A patent/IE55032B1/en not_active IP Right Cessation
- 1983-01-18 JP JP58005413A patent/JPS58124786A/ja active Granted
- 1983-01-18 DK DK017983A patent/DK163145C/da not_active IP Right Cessation
- 1983-01-18 AU AU10550/83A patent/AU564026B2/en not_active Ceased
- 1983-01-18 KR KR1019830000174A patent/KR890000184B1/ko not_active Expired
- 1983-01-18 PT PT76107A patent/PT76107A/pt unknown
1984
- 1984-04-10 ES ES531458A patent/ES531458A0/es active Granted
1987
- 1987-10-20 US US07/112,015 patent/US4788186A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH048428B2 (da)	1992-02-17
CA1214168A (en)	1986-11-18
IE55032B1 (en)	1990-05-09
JPS58124786A (ja)	1983-07-25
AU564026B2 (en)	1987-07-30
EP0085840A1 (en)	1983-08-17
NO161674B (no)	1989-06-05
NO161674C (no)	1989-09-13
DK17983A (da)	1983-07-19
IE830082L (en)	1983-07-18
IL67697A0 (en)	1983-05-15
NO830110L (no)	1983-07-19
FI830100L (fi)	1983-07-19
HU193033B (en)	1987-08-28
ES8601995A1 (es)	1985-11-01
DK163145B (da)	1992-01-27
FI830100A0 (fi)	1983-01-12
ZA83224B (en)	1983-10-26
GR78442B (da)	1984-09-27
KR840003254A (ko)	1984-08-20
EP0085840B1 (en)	1986-10-01
DE3366494D1 (de)	1986-11-06
IL67697A (en)	1990-02-09
PH21834A (en)	1988-03-17
ES531458A0 (es)	1985-11-01
DK163145C (da)	1992-06-22
PT76107A (en)	1983-02-01
FI81350C (fi)	1990-10-10
NZ203021A (en)	1986-05-09
KR890000184B1 (ko)	1989-03-09
FI81350B (fi)	1990-06-29
ATE22562T1 (de)	1986-10-15
US4788186A (en)	1988-11-29
AU1055083A (en)	1983-07-28

Publication	Publication Date	Title
DK17983D0 (da)	1983-01-18	Fremgangsmade til fremstilling af 6-substituerede s-triazol(3,4-a)-ftalazin-derivater
NO164712C (no)	1990-11-07	Analogifremgangsmaate til fremstilling av metylendifosfonsyre-derivater.
NO154905C (no)	1987-01-14	Fremgangsmaate for fremstilling av preparater for behandling av melanomer.
DK267082A (da)	1983-12-15	Fremgangsmaade til fremstilling af et agglomereret, pulverformet maelkeprodukt
IL70585A (en)	1987-02-27	Substituted 4-aminomethylenechromans and-chromenes,their preparation and pharmaceutical compositions containing them
DK93685D0 (da)	1985-02-28	Benzisoselenazolthioner, fremgangsmaade til fremstilling af disse forbindelser og farmaceutiske praeparater indeholdende disse forbindelser
NZ192195A (en)	1981-10-19	1-triazolyl-2-hydroxy-2-phenyl-3-aryl-propanes and pharmaceutical compositions
IL64292A0 (en)	1982-02-28	D-homosteroids,their manufacture and pharmaceutical compositions containing them
ES507807A0 (es)	1982-10-01	Procedimiento para la obtencion de derivados triciclicos de citosina.
NO158871C (no)	1988-11-09	Analogifremgangsmaate for fremstilling av pyridazinderivater.
NO159528C (no)	1989-01-11	Analogifremgangsmaate ved fremstilling av terapeutisk aktive aminoguanidinderivater.
ES492143A0 (es)	1980-12-16	Procedimiento para la obtencion de derivados de 3,4,5-trihi-droxipiperidina
DE3262124D1 (en)	1985-03-14	Saturated derivatives of aminocyclitols, their preparation and pharmaceutical preparations containing them
IL60323A0 (en)	1980-09-16	Pseudotrisaccharide compounds,their preparation and their medicinal use
NO163529C (no)	1990-06-13	Analogifremgangsmaate til fremstilling av terapeutisk aktive substituerte azabicykloalkaner.
DK159769C (da)	1991-04-22	Resorcinderivater og analogifremgangsmaade til fremstilling heraf, farmaceutiske praeparater indeholdende disse, samt fremgangsmaade til fremstilling af disse farmaceutiske praeparater
DE3368933D1 (en)	1987-02-12	Phosphate derivatives, process for preparation thereof and pharmaceutical compositions of the same
IL58367A (en)	1984-05-31	2-substituted-3-heterocyclylindoles,their preparation and pharmaceutical compositions containing them
ES522653A0 (es)	1984-09-16	Procedimiento de preparacion de derivados de piperacina.
NO903181D0 (no)	1990-07-17	Analogifremgangsmaate ved fremstilling av 4-amino-6,7-dimetoksy-2(6,7-dimetoksy-1,2,3,4-tetrahydroisokinol-2-yl)kinolin.
DK123685D0 (da)	1985-03-19	Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-(1,4)-benzodiazepinderivater
AR226096A1 (es)	1982-05-31	Procedimiento para la preparacion de n,n-dimetil-10-(1-aza(2,2,2)-biciclo-3-octil)10h-2-fenotiazinsulfonamida
ES516812A0 (es)	1984-01-16	Procedimiento de preparacion de nuevos derivados de pirrol.

Legal Events

Date	Code	Title	Description
1993-09-27	PBP	Patent lapsed