DK1740574T3 - 4-amino-5-cyanopyrimidinderivater - Google Patents

4-amino-5-cyanopyrimidinderivater

Info

Publication number: DK1740574T3
Authority: DK; Denmark
Prior art keywords: amino; cyanopyrimidine derivatives; cyanopyrimidine; derivatives
Prior art date: 2004-04-30

Application number

DK05738867T

Other languages

English (en)

Inventor

Masaya Kato

Norifumi Sato

Minoru Okada

Tetsuyuki Uno

Nobuaki Ito

Yasuhiro Takeji

Hisashi Shinohara

Masahiro Fuwa

Original Assignee

Otsuka Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-04-30

Filing date

2005-04-28

Publication date

2007-10-15

2005-04-28 Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd

2007-10-15 Application granted granted Critical

2007-10-15 Publication of DK1740574T3 publication Critical patent/DK1740574T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Ophthalmology & Optometry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK05738867T 2004-04-30 2005-04-28 4-amino-5-cyanopyrimidinderivater DK1740574T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2004135999		2004-04-30
PCT/JP2005/008568 WO2005105778A2 (en)	2004-04-30	2005-04-28	4-amino-5-cyanopyrimidine derivatives

Publications (1)

Publication Number	Publication Date
DK1740574T3 true DK1740574T3 (da)	2007-10-15

Family

ID=35242255

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05738867T DK1740574T3 (da)	2004-04-30	2005-04-28	4-amino-5-cyanopyrimidinderivater

Country Status (21)

Country	Link
US (2)	US7834002B2 (da)
EP (1)	EP1740574B1 (da)
KR (1)	KR101279689B1 (da)
CN (1)	CN1976922B (da)
AR (1)	AR049085A1 (da)
AT (1)	ATE365731T1 (da)
AU (1)	AU2005238391B2 (da)
BR (1)	BRPI0509454A (da)
CA (1)	CA2563846C (da)
CY (1)	CY1106764T1 (da)
DE (1)	DE602005001508T2 (da)
DK (1)	DK1740574T3 (da)
ES (1)	ES2288744T3 (da)
MX (1)	MXPA06012639A (da)
MY (1)	MY138996A (da)
PL (1)	PL1740574T3 (da)
PT (1)	PT1740574E (da)
RU (1)	RU2386628C2 (da)
SI (1)	SI1740574T1 (da)
TW (1)	TWI346109B (da)
WO (1)	WO2005105778A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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CA2665490C (en) *	2006-10-03	2014-06-17	The Trustees Of The University Of Pennsylvania	Method for treatment of macular degeneration
TWI452044B (zh)	2007-06-15	2014-09-11	Mitsubishi Tanabe Pharma Corp	嗎啉衍生物
US8466176B2 (en)	2008-03-19	2013-06-18	Bayer Cropscience Ag	Fungicide hydroximoyl-tetrazole derivatives
AR075196A1 (es) *	2009-02-03	2011-03-16	Otsuka Pharma Co Ltd	Un derivado de cianopirimidina para el tratamiento de una enfermedad ocular
SG11201403979TA (en) *	2012-01-26	2014-08-28	Inotek Pharmaceuticals Corp	Anhydrous polymorphs of (2r,3s,4r,5r)-5-(6-(cyclopentylamino)-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl) } methyl nitrate and processes of preparation thereof
EP2816023A4 (en) *	2012-02-13	2015-09-09	Takeda Pharmaceutical	AROMATIC RING CONNECTION
WO2019051396A1 (en) *	2017-09-08	2019-03-14	President And Fellows Of Harvard College	SMALL MOLECULE INHIBITORS OF EBOLA VIRUSES AND LASSA FEVER, AND METHODS OF USE THEREOF
WO2019072143A1 (zh) *	2017-10-11	2019-04-18	上海迪诺医药科技有限公司	4-氨基吡啶衍生物、其药物组合物、制备方法及应用
WO2025038781A1 (en) *	2023-08-15	2025-02-20	Lucy Therapeutics, Inc.	Adenosine ligands for the treatment of neurological disorders or chronic heart failure

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WO1990005526A1 (fr)	1988-11-15	1990-05-31	Yamasa Shoyu Kabushiki Kaisha	Agent de traitement et de prophylaxie des troubles ischemiques du c×ur ou du cerveau
IT1254915B (it)	1992-04-24	1995-10-11	Gloria Cristalli	Derivati di adenosina ad attivita' a2 agonista
US6448235B1 (en)	1994-07-11	2002-09-10	University Of Virginia Patent Foundation	Method for treating restenosis with A2A adenosine receptor agonists
US5877180A (en)	1994-07-11	1999-03-02	University Of Virginia Patent Foundation	Method for treating inflammatory diseases with A2a adenosine receptor agonists
US6514949B1 (en)	1994-07-11	2003-02-04	University Of Virginia Patent Foundation	Method compositions for treating the inflammatory response
TW528755B (en)	1996-12-24	2003-04-21	Glaxo Group Ltd	2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
SE9703378D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	New compounds
YU44900A (sh)	1998-01-31	2003-01-31	Glaxo Group Limited	Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
AR017457A1 (es)	1998-02-14	2001-09-05	Glaxo Group Ltd	Compuestos derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol, procesos para su preparacion, composiciones que los contienen y su uso en terapia para el tratamiento de enfermedades inflamatorias.
GB9813540D0 (en)	1998-06-23	1998-08-19	Glaxo Group Ltd	Chemical compounds
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DE10110438A1 (de)	2001-03-05	2002-09-19	Bayer Ag	Substituierte 2-Oxy-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung
DE10110747A1 (de)	2001-03-07	2002-09-12	Bayer Ag	Substituierte 2,6-Diamino-3,5-dicyano-4-aryl-pyridine und ihre Verwendung
DE10110754A1 (de)	2001-03-07	2002-09-19	Bayer Ag	Substituierte 2-Thio-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung
DE10115922A1 (de)	2001-03-30	2002-10-10	Bayer Ag	Cyclisch substituierte 2-Thio-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung
DE10115945A1 (de)	2001-03-30	2002-10-02	Bayer Ag	Substituierte 2-Carba-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung
DE10134481A1 (de)	2001-07-16	2003-01-30	Bayer Ag	Substituierte 2-Thio-3,5-dicyano-4-phenyl-6-aminopyridine und ihre Verwendung
JP2003055395A (ja)	2001-08-10	2003-02-26	Toa Eiyo Ltd	アデノシン誘導体
DE10238113A1 (de)	2001-12-11	2003-06-18	Bayer Ag	Substituierte 2-Thio-3,5-dicyano-4-phenyl-6-aminopyridine und ihre Verwendung
JP2003206230A (ja)	2002-01-10	2003-07-22	Yamanouchi Pharmaceut Co Ltd	シアノヘテロ環誘導体又はその塩

2005
- 2005-04-26 TW TW094113204A patent/TWI346109B/zh not_active IP Right Cessation
- 2005-04-27 MY MYPI20051851A patent/MY138996A/en unknown
- 2005-04-28 RU RU2006142323/04A patent/RU2386628C2/ru not_active IP Right Cessation
- 2005-04-28 BR BRPI0509454-2A patent/BRPI0509454A/pt not_active Application Discontinuation
- 2005-04-28 KR KR1020067025266A patent/KR101279689B1/ko not_active Expired - Fee Related
- 2005-04-28 EP EP05738867A patent/EP1740574B1/en not_active Expired - Lifetime
- 2005-04-28 ES ES05738867T patent/ES2288744T3/es not_active Expired - Lifetime
- 2005-04-28 DK DK05738867T patent/DK1740574T3/da active
- 2005-04-28 CA CA2563846A patent/CA2563846C/en not_active Expired - Fee Related
- 2005-04-28 WO PCT/JP2005/008568 patent/WO2005105778A2/en not_active Ceased
- 2005-04-28 PL PL05738867T patent/PL1740574T3/pl unknown
- 2005-04-28 US US11/579,067 patent/US7834002B2/en not_active Expired - Fee Related
- 2005-04-28 DE DE602005001508T patent/DE602005001508T2/de not_active Expired - Lifetime
- 2005-04-28 AU AU2005238391A patent/AU2005238391B2/en not_active Ceased
- 2005-04-28 CN CN2005800212589A patent/CN1976922B/zh not_active Expired - Fee Related
- 2005-04-28 MX MXPA06012639A patent/MXPA06012639A/es active IP Right Grant
- 2005-04-28 AT AT05738867T patent/ATE365731T1/de active
- 2005-04-28 SI SI200530047T patent/SI1740574T1/sl unknown
- 2005-04-28 PT PT05738867T patent/PT1740574E/pt unknown
- 2005-04-29 AR ARP050101725A patent/AR049085A1/es not_active Application Discontinuation
2007
- 2007-07-25 CY CY20071100998T patent/CY1106764T1/el unknown
2010
- 2010-09-22 US US12/923,451 patent/US7989446B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HK1100775A1 (en)	2007-09-28
EP1740574B1 (en)	2007-06-27
RU2006142323A (ru)	2008-06-10
AU2005238391A1 (en)	2005-11-10
DE602005001508T2 (de)	2008-02-28
MY138996A (en)	2009-08-28
MXPA06012639A (es)	2006-12-15
US7989446B2 (en)	2011-08-02
CN1976922B (zh)	2012-09-05
TW200540161A (en)	2005-12-16
US20080182854A1 (en)	2008-07-31
CN1976922A (zh)	2007-06-06
EP1740574A2 (en)	2007-01-10
US7834002B2 (en)	2010-11-16
RU2386628C2 (ru)	2010-04-20
PL1740574T3 (pl)	2007-11-30
CA2563846A1 (en)	2005-11-10
US20110009620A1 (en)	2011-01-13
DE602005001508D1 (de)	2007-08-09
TWI346109B (en)	2011-08-01
ES2288744T3 (es)	2008-01-16
CY1106764T1 (el)	2012-05-23
SI1740574T1 (sl)	2007-12-31
WO2005105778A3 (en)	2006-10-26
WO2005105778A2 (en)	2005-11-10
KR101279689B1 (ko)	2013-06-27
KR20070008715A (ko)	2007-01-17
ATE365731T1 (de)	2007-07-15
PT1740574E (pt)	2007-09-06
BRPI0509454A (pt)	2007-09-04
AR049085A1 (es)	2006-06-28
AU2005238391B2 (en)	2010-12-16
CA2563846C (en)	2011-12-20

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ATE383361T1 (de)	2008-01-15	Pyrrazolopyrimidinderivate
DE502005005628D1 (de)	2008-11-20	Wischblatt
ATE553079T1 (de)	2012-04-15	Heteroarylphenylharnstoffderivat
EP1718903A4 (en)	2007-10-10	HYBRID HEATING APPARATUS
ATE417830T1 (de)	2009-01-15	Sulfonylbenzimidazolderivate
DE502005003777D1 (de)	2008-05-29	Thiazolyl-dihydro-indazole
ATE459633T1 (de)	2010-03-15	Makrolide
DE602005015952D1 (de)	2009-09-24	Pulversiebvorrichtung
DE602006010581D1 (de)	2009-12-31	4-phenyl-6-substituierte pyrimidin-2-carbonitrilderivate
DE502005006395D1 (de)	2009-02-12	Verschlusskappe
DE602005018298D1 (de)	2010-01-28	Schwingarmstruktur
ATE485294T1 (de)	2010-11-15	Azaindol-2-carboxamid-derivate
ATE430142T1 (de)	2009-05-15	Phenylpiperazin-methanon-derivate
ATE527255T1 (de)	2011-10-15	Aryl-isoxazol-4-yl-imidazol-derivate
DE502005007739D1 (de)	2009-09-03	Kranballastierungssystem
DK1971588T3 (da)	2012-10-22	Tiglien-3-onderivater
DE602005003649D1 (de)	2008-01-17	Hydraulikhammer
DE602005005896D1 (de)	2008-05-21	Bogenfalzeinrichtung
ATE404542T1 (de)	2008-08-15	4-phenylpyrimidin-2-carbonitrilderivate
ATE365731T1 (de)	2007-07-15	4-amino-5-cyanopyrimidinderivate
DE112005000794T5 (de)	2007-05-16	Urethanspritzpistolenanordnung