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DK1633340T3 - Forbindelser til behandling af stofskifteforstyrrelser - Google Patents

Forbindelser til behandling af stofskifteforstyrrelser

Info

Publication number
DK1633340T3
DK1633340T3 DK04759257.1T DK04759257T DK1633340T3 DK 1633340 T3 DK1633340 T3 DK 1633340T3 DK 04759257 T DK04759257 T DK 04759257T DK 1633340 T3 DK1633340 T3 DK 1633340T3
Authority
DK
Denmark
Prior art keywords
carbon atoms
ring
alkyl
hydrogen
treatment
Prior art date
Application number
DK04759257.1T
Other languages
English (en)
Inventor
Kirvin L Hodge
Shalini Sharma
Borstel Reid W Von
Stephen D Wolpe
Original Assignee
Wellstat Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellstat Therapeutics Corp filed Critical Wellstat Therapeutics Corp
Application granted granted Critical
Publication of DK1633340T3 publication Critical patent/DK1633340T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK04759257.1T 2003-04-15 2004-04-08 Forbindelser til behandling af stofskifteforstyrrelser DK1633340T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46296003P 2003-04-15 2003-04-15
PCT/US2004/010799 WO2004091486A2 (en) 2003-04-15 2004-04-08 Compounds for the treatment of metabolic disorders

Publications (1)

Publication Number Publication Date
DK1633340T3 true DK1633340T3 (da) 2011-02-07

Family

ID=33300020

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04759257.1T DK1633340T3 (da) 2003-04-15 2004-04-08 Forbindelser til behandling af stofskifteforstyrrelser

Country Status (24)

Country Link
US (2) US7514555B2 (da)
EP (1) EP1633340B1 (da)
JP (2) JP4766693B2 (da)
KR (1) KR101127390B1 (da)
CN (2) CN1774244A (da)
AT (1) ATE487474T1 (da)
AU (1) AU2004229418B2 (da)
BR (1) BRPI0409469B1 (da)
CA (1) CA2521621C (da)
CY (1) CY1111310T1 (da)
DE (1) DE602004030004D1 (da)
DK (1) DK1633340T3 (da)
ES (1) ES2353601T3 (da)
IL (1) IL171269A (da)
MX (1) MXPA05011042A (da)
NO (1) NO20054791L (da)
NZ (1) NZ542739A (da)
PL (1) PL1633340T3 (da)
PT (1) PT1633340E (da)
RU (1) RU2358722C2 (da)
SI (1) SI1633340T1 (da)
UA (1) UA80195C2 (da)
WO (1) WO2004091486A2 (da)
ZA (1) ZA200507704B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4711621B2 (ja) * 2001-06-12 2011-06-29 ウェルスタット セラピューティクス コーポレイション 代謝障害治療用化合物
EP1556085A4 (en) * 2002-11-01 2012-08-22 Wellstat Therapeutics Corp COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
EP1601251B1 (en) 2003-02-13 2014-11-12 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
BRPI0409469B1 (pt) * 2003-04-15 2016-04-26 Wellstat Therapeutics Corp compostos para o tratamento de distúrbios metabólicos, seu uso e composição farmacêutica compreendendo os mesmos
DE602004024382D1 (de) 2003-04-22 2010-01-14 Wellstat Therapeutics Corp Verbindungen zur behandlung von stoffwechselstörungen
CA2522738C (en) * 2003-04-30 2011-11-08 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
ATE502631T1 (de) * 2003-08-20 2011-04-15 Wellstat Therapeutics Corp Verbindungen zur behandlung von stoffwechselstörungen
EP1868595B1 (en) * 2005-04-01 2012-01-11 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
UA95613C2 (ru) * 2005-11-09 2011-08-25 Уеллстат Терепьютикс Корпорейшн Соединения для лечения расстройсв метаболизма
US7947735B2 (en) * 2006-01-25 2011-05-24 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
WO2007087505A2 (en) 2006-01-25 2007-08-02 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
EP1976510A4 (en) * 2006-01-25 2010-06-09 Wellstat Therapeutics Corp COMPOUNDS FOR THE TREATMENT OF METABOLISM DISORDER
AU2007212104A1 (en) * 2006-02-02 2007-08-16 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
CA2637884A1 (en) * 2006-02-13 2007-08-23 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
US20100227901A1 (en) * 2006-02-28 2010-09-09 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
KR20080106455A (ko) * 2006-03-31 2008-12-05 웰스태트 테러퓨틱스 코포레이션 대사장애의 조합치료
EP2019673A4 (en) * 2006-05-18 2010-06-16 Wellstat Therapeutics Corp COMPOUNDS FOR THE TREATMENT OF METABOLISM DISORDER
US20100234464A1 (en) * 2006-06-09 2010-09-16 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
NZ574664A (en) * 2006-08-17 2012-06-29 Wellstat Therapeutics Corp Combination treatment for metabolic disorders comprising an incretin mimetic such as exendin or a dppv iv inhibitor
EP2240024A4 (en) * 2008-01-15 2014-05-21 Wellstat Therapeutics Corp COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
JP5339545B2 (ja) 2008-03-13 2013-11-13 ウェルスタット セラピューティクス コーポレイション 尿酸を減少させる化合物及び方法
WO2009137381A1 (en) * 2008-05-05 2009-11-12 Wellstat Therapeutics Corporation Synthesis of 4-[3-(2,6-dimethylbenzyloxy)phenyl]-4-oxobutanoic acid
US8703991B2 (en) 2008-11-04 2014-04-22 Wellstat Therapeutics Corporation Synthesis of (phenylalkyloxy)phenyl-oxobutanoic acids
JP6458784B2 (ja) * 2016-08-03 2019-01-30 横河電機株式会社 駆動回路および電磁流量計

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JP4711621B2 (ja) * 2001-06-12 2011-06-29 ウェルスタット セラピューティクス コーポレイション 代謝障害治療用化合物
JP4825375B2 (ja) 2001-08-28 2011-11-30 株式会社 資生堂 ジチアゾール化合物及びマトリックスメタロプロテアーゼ活性阻害剤、皮膚外用剤
EP1556085A4 (en) 2002-11-01 2012-08-22 Wellstat Therapeutics Corp COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
EP1601251B1 (en) 2003-02-13 2014-11-12 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
BRPI0409469B1 (pt) 2003-04-15 2016-04-26 Wellstat Therapeutics Corp compostos para o tratamento de distúrbios metabólicos, seu uso e composição farmacêutica compreendendo os mesmos
DE602004024382D1 (de) 2003-04-22 2010-01-14 Wellstat Therapeutics Corp Verbindungen zur behandlung von stoffwechselstörungen
CA2522738C (en) 2003-04-30 2011-11-08 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
ATE502631T1 (de) 2003-08-20 2011-04-15 Wellstat Therapeutics Corp Verbindungen zur behandlung von stoffwechselstörungen
US7163470B2 (en) 2004-06-25 2007-01-16 Callaway Golf Company Golf club head
EP1868595B1 (en) 2005-04-01 2012-01-11 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
US7947735B2 (en) 2006-01-25 2011-05-24 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
WO2007087505A2 (en) 2006-01-25 2007-08-02 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders

Also Published As

Publication number Publication date
EP1633340B1 (en) 2010-11-10
JP2011178808A (ja) 2011-09-15
HK1084026A1 (en) 2006-07-21
AU2004229418B2 (en) 2008-07-31
WO2004091486A2 (en) 2004-10-28
JP5371062B2 (ja) 2013-12-18
CN1774244A (zh) 2006-05-17
MXPA05011042A (es) 2005-12-15
CY1111310T1 (el) 2015-08-05
US20090156681A1 (en) 2009-06-18
UA80195C2 (en) 2007-08-27
US7514555B2 (en) 2009-04-07
ATE487474T1 (de) 2010-11-15
WO2004091486A3 (en) 2005-01-20
NZ542739A (en) 2007-02-23
ZA200507704B (en) 2007-02-28
EP1633340A4 (en) 2009-05-27
JP2006523696A (ja) 2006-10-19
BRPI0409469B1 (pt) 2016-04-26
KR101127390B1 (ko) 2012-03-23
ES2353601T3 (es) 2011-03-03
KR20050121262A (ko) 2005-12-26
CA2521621C (en) 2011-11-01
PT1633340E (pt) 2011-02-22
EP1633340A2 (en) 2006-03-15
RU2358722C2 (ru) 2009-06-20
NO20054791L (no) 2005-12-20
JP4766693B2 (ja) 2011-09-07
BRPI0409469A (pt) 2006-04-18
RU2005135441A (ru) 2006-03-20
IL171269A (en) 2011-09-27
PL1633340T3 (pl) 2011-04-29
DE602004030004D1 (de) 2010-12-23
US20060014784A1 (en) 2006-01-19
US7973052B2 (en) 2011-07-05
SI1633340T1 (sl) 2011-02-28
CA2521621A1 (en) 2004-10-28
CN101912380A (zh) 2010-12-15
NO20054791D0 (no) 2005-10-18
AU2004229418A1 (en) 2004-10-28

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