DK160818C - N-ring-holdige glycerolderivater, fremgangsmaade til fremstilling deraf, anvendelse deraf til fremstilling af et blodpladeaktiveringsfaktorhaemmende middel samt laegemidler indeholdende en saadan forbindelse - Google Patents
N-ring-holdige glycerolderivater, fremgangsmaade til fremstilling deraf, anvendelse deraf til fremstilling af et blodpladeaktiveringsfaktorhaemmende middel samt laegemidler indeholdende en saadan forbindelseInfo
- Publication number
- DK160818C DK160818C DK514284A DK514284A DK160818C DK 160818 C DK160818 C DK 160818C DK 514284 A DK514284 A DK 514284A DK 514284 A DK514284 A DK 514284A DK 160818 C DK160818 C DK 160818C
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- processes
- compound
- platelet activation
- activation factor
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 150000002314 glycerols Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000010118 platelet activation Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH698583 | 1983-12-30 | ||
| CH698583 | 1983-12-30 | ||
| CH449884 | 1984-09-20 | ||
| CH449884 | 1984-09-20 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK514284D0 DK514284D0 (da) | 1984-10-26 |
| DK514284A DK514284A (da) | 1985-07-01 |
| DK160818B DK160818B (da) | 1991-04-22 |
| DK160818C true DK160818C (da) | 1991-10-07 |
Family
ID=25695617
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK514284A DK160818C (da) | 1983-12-30 | 1984-10-26 | N-ring-holdige glycerolderivater, fremgangsmaade til fremstilling deraf, anvendelse deraf til fremstilling af et blodpladeaktiveringsfaktorhaemmende middel samt laegemidler indeholdende en saadan forbindelse |
| DK200590A DK200590A (da) | 1983-12-30 | 1990-08-21 | Glycerolderivater |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK200590A DK200590A (da) | 1983-12-30 | 1990-08-21 | Glycerolderivater |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4731373A (da) |
| EP (1) | EP0147768B1 (da) |
| AU (1) | AU571625B2 (da) |
| CA (1) | CA1266476A (da) |
| DE (1) | DE3476661D1 (da) |
| DK (2) | DK160818C (da) |
| ES (2) | ES539136A0 (da) |
| FI (1) | FI82686C (da) |
| HU (1) | HU195775B (da) |
| IL (1) | IL73920A (da) |
| MC (1) | MC1639A1 (da) |
| NO (1) | NO165192C (da) |
| NZ (1) | NZ210633A (da) |
| PH (1) | PH21482A (da) |
| PT (1) | PT79783B (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4737518A (en) * | 1984-04-03 | 1988-04-12 | Takeda Chemical Industries, Ltd. | Lipid derivatives, their production and use |
| EP0195016A1 (en) * | 1984-08-23 | 1986-09-24 | Sandoz Ag | Cyclimmonium salts |
| US4863941A (en) * | 1985-06-18 | 1989-09-05 | Hoffmann-La Roche Inc. | Glycerol derivatives |
| GB8528959D0 (en) * | 1985-11-25 | 1986-01-02 | Leo Pharm Prod Ltd | Chemical compounds |
| US5089657A (en) * | 1987-03-11 | 1992-02-18 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
| DE3879024T2 (de) * | 1987-07-31 | 1993-10-07 | Takeda Chemical Industries Ltd | Pyridinium-Derivate, ihre Herstellung und Verwendung. |
| US4920134A (en) * | 1987-08-07 | 1990-04-24 | Takeda Chemical Industries, Ltd. | 2-O-pyrimidinyl glycerol derivatives |
| ES2005031A6 (es) * | 1987-10-13 | 1989-02-16 | Uriach & Cia Sa J | Procedimiento para la obtencion de 1,3-dioxolanos 2,4-disustituidos. |
| US5185334A (en) * | 1989-07-31 | 1993-02-09 | Schering Corporation | 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use |
| WO1989007100A1 (en) * | 1988-02-05 | 1989-08-10 | Schering Corporation | 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use |
| WO1989007099A1 (en) * | 1988-02-05 | 1989-08-10 | Schering Corporation | 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use |
| EP0336142A3 (en) * | 1988-04-04 | 1991-04-24 | American Cyanamid Company | Novel antagonists of platelet activating factor |
| US5273985A (en) * | 1988-07-04 | 1993-12-28 | Eisai Co., Ltd. | Glycerin derivative and its pharmacological use |
| FI97883C (fi) * | 1988-07-04 | 1997-03-10 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen glyserolijohdannaisen valmistamiseksi |
| EP0356765A3 (en) * | 1988-08-19 | 1991-08-07 | Takeda Chemical Industries, Ltd. | Carboxylic acid derivatives, their production and use |
| ES2013834A6 (es) * | 1989-01-30 | 1990-06-01 | Uriach & Cia Sa J | Procedimiento para la obtencion de derivados 4-sustituidos de 2-alcoxitetrahidrofurano. |
| US4981860A (en) * | 1989-01-30 | 1991-01-01 | Takeda Chemical Industries, Ltd. | Pyridinium nitrate, composition containing same and their use for inhibiting platelet activating factor |
| ES2010145A6 (es) * | 1989-03-02 | 1989-10-16 | Uriach & Cia Sa J | Procedimiento para la obtencion de derivados de la 2-picolilamina. |
| US5391785A (en) * | 1990-01-16 | 1995-02-21 | La Jolla Pharmaceutial Company | Intermediates for providing functional groups on the 5' end of oligonucleotides |
| IE922292A1 (en) * | 1991-07-15 | 1993-01-27 | Jolla Pharma | Modified phosphorous intermediates for providing functional¹groups on the 5' end of oligonucleotides |
| ES2062943B1 (es) * | 1993-03-23 | 1995-11-16 | Uriach & Cia Sa J | Nuevos derivados de la (2-metil-3-piridil) cianometilpiperazinas. |
| KR100361933B1 (ko) * | 1993-09-08 | 2003-02-14 | 라 졸라 파마슈티칼 컴파니 | 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 |
| US6458953B1 (en) * | 1998-12-09 | 2002-10-01 | La Jolla Pharmaceutical Company | Valency platform molecules comprising carbamate linkages |
| EP1292337A2 (en) * | 2000-06-08 | 2003-03-19 | La Jolla Pharmaceutical | Multivalent platform molecules comprising high molecular weight polyethylene oxide |
| RU2414453C2 (ru) * | 2008-07-17 | 2011-03-20 | Сергей Иванович МАЛЕКИН | 1-алкил-2-алкилкарбамоил-глицерины, обладающие антигипертензивной активностью, и способ их получения |
| CN107082870A (zh) | 2012-03-30 | 2017-08-22 | 三菱化学株式会社 | 环氧组合物 |
| RU2621347C1 (ru) * | 2016-05-27 | 2017-06-02 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет "Министерства здравоохранения Российской Федерации (ГБОУ ВПО СибГМУ Минздрава России) | Способ получения 1-алкил-2-алкилкарбамоилглицеринов |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE932611C (de) * | 1949-12-22 | 1955-09-05 | Ciba Geigy | Verfahren zur Herstellung von Polyalkylenglykolaethern isocyclischer Verbindungen |
| DE1199254B (de) * | 1963-09-20 | 1965-08-26 | Krewel Leuffen Gmbh | Verfahren zur Herstellung von O, N-Dicarbaethoxyderivaten von substituierten 1, 3-Aminoalkoholen |
| NL133296C (da) * | 1966-12-30 | |||
| NL6916355A (da) * | 1968-11-02 | 1970-05-06 | ||
| US3686238A (en) * | 1970-01-19 | 1972-08-22 | Syntex Corp | Glycerol esterified with 2-naphthyl-acetic acids and fatty acids |
| US3671557A (en) * | 1970-09-17 | 1972-06-20 | Smith Kline French Lab | 1,2-diacylglycerol 3-(2,2,2-trichloroethyl) carbonates |
| DE2422170C2 (de) * | 1974-05-08 | 1982-09-23 | Bayer Ag, 5090 Leverkusen | Polymerisierbare N,N-disubstituierte Carbamoyloxyalkylcarbonsäureester, Verfahren zu ihrer Herstellung und ihre Verwendung |
| DD121507B1 (de) * | 1975-09-29 | 1989-11-29 | Hans Brachwitz | Verfahren zur herstellung von 1-o-acyl-und 1-0-alkyl-2-halogenpropandiol-(1,3) |
| GB1514389A (en) * | 1975-12-08 | 1978-06-14 | Abbott Lab | Glycerides with antibacterial properties |
| DE2820892A1 (de) * | 1978-05-12 | 1979-11-22 | Nattermann A & Cie | Neue strukturanaloga von glyveriden und verfahren zu deren herstellung |
| US4551532A (en) * | 1980-05-08 | 1985-11-05 | Takeda Chemical Industries, Ltd. | Ethylene glycol derivatives having anti-protozoan, anti-fungal and anti-tumor activity |
| EP0054715A3 (de) * | 1980-12-18 | 1982-09-22 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Propionsäureester, Herstellung dieser Verbindungen, Unkrautbekämpfungsmittel, die diese Verbindungen als Wirkstoffe enthalten, sowie Verwendung solcher Verbindungen und Mittel zur Bekämpfung von Unkräutern |
| US4493832A (en) * | 1981-07-03 | 1985-01-15 | Fujisawa Pharmaceutical Co., Ltd. | Certain glycerol-phosphoryl choline derivatives, compositions containing same and method of using same |
| JPS58192825A (ja) * | 1982-05-06 | 1983-11-10 | Takeda Chem Ind Ltd | グリセロール誘導体 |
| EP0094586A3 (en) * | 1982-05-13 | 1984-06-06 | Ono Pharmaceutical Co., Ltd. | Glycerol derivatives, process for preparing same and pharmaceutical composition containing same |
| JPS5988447A (ja) * | 1982-11-11 | 1984-05-22 | Ono Pharmaceut Co Ltd | グリセリン誘導体、その製造方法及びその誘導体を含有する薬剤 |
| JPS60104066A (ja) * | 1983-11-10 | 1985-06-08 | Ono Pharmaceut Co Ltd | グリセリン誘導体 |
-
1984
- 1984-10-26 DK DK514284A patent/DK160818C/da not_active Application Discontinuation
- 1984-11-01 CA CA000466850A patent/CA1266476A/en not_active Expired
- 1984-11-05 FI FI844332A patent/FI82686C/fi not_active IP Right Cessation
- 1984-11-21 NO NO844635A patent/NO165192C/no unknown
- 1984-12-10 US US06/679,734 patent/US4731373A/en not_active Expired - Fee Related
- 1984-12-18 EP EP84115698A patent/EP0147768B1/de not_active Expired
- 1984-12-18 DE DE8484115698T patent/DE3476661D1/de not_active Expired
- 1984-12-19 NZ NZ210633A patent/NZ210633A/xx unknown
- 1984-12-24 IL IL73920A patent/IL73920A/xx unknown
- 1984-12-26 PH PH31647A patent/PH21482A/en unknown
- 1984-12-27 MC MC841745A patent/MC1639A1/fr unknown
- 1984-12-28 HU HU844853A patent/HU195775B/hu not_active IP Right Cessation
- 1984-12-28 ES ES539136A patent/ES539136A0/es active Granted
- 1984-12-28 PT PT79783A patent/PT79783B/pt unknown
- 1984-12-28 AU AU37196/84A patent/AU571625B2/en not_active Ceased
-
1985
- 1985-09-16 ES ES547020A patent/ES8701138A1/es not_active Expired
-
1990
- 1990-08-21 DK DK200590A patent/DK200590A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FI82686C (fi) | 1991-04-10 |
| FI82686B (fi) | 1990-12-31 |
| DE3476661D1 (en) | 1989-03-16 |
| EP0147768A2 (de) | 1985-07-10 |
| AU571625B2 (en) | 1988-04-21 |
| IL73920A0 (en) | 1985-03-31 |
| DK200590D0 (da) | 1990-08-21 |
| DK514284D0 (da) | 1984-10-26 |
| ES547020A0 (es) | 1986-11-16 |
| PH21482A (en) | 1987-10-28 |
| HU195775B (en) | 1988-07-28 |
| HUT37112A (en) | 1985-11-28 |
| NO844635L (no) | 1985-07-01 |
| ES8701138A1 (es) | 1986-11-16 |
| PT79783B (en) | 1987-01-05 |
| NZ210633A (en) | 1988-08-30 |
| ES8603374A1 (es) | 1986-01-01 |
| EP0147768A3 (en) | 1985-10-09 |
| EP0147768B1 (de) | 1989-02-08 |
| CA1266476A (en) | 1990-03-06 |
| FI844332L (fi) | 1985-07-01 |
| FI844332A0 (fi) | 1984-11-05 |
| NO165192B (no) | 1990-10-01 |
| DK200590A (da) | 1990-08-21 |
| PT79783A (en) | 1985-01-01 |
| US4731373A (en) | 1988-03-15 |
| DK160818B (da) | 1991-04-22 |
| IL73920A (en) | 1988-06-30 |
| NO165192C (no) | 1991-01-09 |
| MC1639A1 (fr) | 1986-01-09 |
| AU3719684A (en) | 1985-07-04 |
| DK514284A (da) | 1985-07-01 |
| ES539136A0 (es) | 1986-01-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed | ||
| AHS | Application shelved for other reasons than non-payment |