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DK1606406T4 - Short Interfering RNA (siRNA) Analogues - Google Patents

Short Interfering RNA (siRNA) Analogues

Info

Publication number
DK1606406T4
DK1606406T4 DK04722233.6T DK04722233T DK1606406T4 DK 1606406 T4 DK1606406 T4 DK 1606406T4 DK 04722233 T DK04722233 T DK 04722233T DK 1606406 T4 DK1606406 T4 DK 1606406T4
Authority
DK
Denmark
Prior art keywords
sirna
analogues
short interfering
lna
nucleic acid
Prior art date
Application number
DK04722233.6T
Other languages
English (en)
Other versions
DK1606406T3 (da
Inventor
Joacim Elmen
Troels Koch
Anders Malling Soerensen
Henrik Oerum
Claes Wahlestedt
Zicai Liang
Original Assignee
Santaris Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44597267&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1606406(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Santaris Pharma As filed Critical Santaris Pharma As
Publication of DK1606406T3 publication Critical patent/DK1606406T3/da
Application granted granted Critical
Publication of DK1606406T4 publication Critical patent/DK1606406T4/da

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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DK04722233.6T 2003-03-21 2004-03-22 Short Interfering RNA (siRNA) Analogues DK1606406T4 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US45688803P 2003-03-21 2003-03-21
DKPA200300442 2003-03-21
DKPA200301625 2003-10-31
DKPA200400145 2004-01-30
PCT/DK2004/000192 WO2004083430A2 (en) 2003-03-21 2004-03-22 SHORT INTERFERING RNA (siRNA) ANALOGUES

Publications (2)

Publication Number Publication Date
DK1606406T3 DK1606406T3 (da) 2009-12-14
DK1606406T4 true DK1606406T4 (da) 2013-12-16

Family

ID=44597267

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04722233.6T DK1606406T4 (da) 2003-03-21 2004-03-22 Short Interfering RNA (siRNA) Analogues
DK09169380.4T DK2141234T3 (da) 2003-03-21 2004-03-22 Korte interfererende RNA (siRNA) analoger

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09169380.4T DK2141234T3 (da) 2003-03-21 2004-03-22 Korte interfererende RNA (siRNA) analoger

Country Status (10)

Country Link
US (3) US8653252B2 (da)
EP (2) EP1606406B2 (da)
JP (1) JP4755972B2 (da)
AT (1) ATE443765T1 (da)
AU (1) AU2004221760B2 (da)
CA (1) CA2519860C (da)
DE (1) DE602004023279D1 (da)
DK (2) DK1606406T4 (da)
ES (2) ES2332178T5 (da)
WO (1) WO2004083430A2 (da)

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US7812149B2 (en) 1996-06-06 2010-10-12 Isis Pharmaceuticals, Inc. 2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
US9096636B2 (en) 1996-06-06 2015-08-04 Isis Pharmaceuticals, Inc. Chimeric oligomeric compounds and their use in gene modulation
EP1572902B1 (en) 2002-02-01 2014-06-11 Life Technologies Corporation HIGH POTENCY siRNAS FOR REDUCING THE EXPRESSION OF TARGET GENES
US20060009409A1 (en) 2002-02-01 2006-01-12 Woolf Tod M Double-stranded oligonucleotides
WO2003064626A2 (en) 2002-02-01 2003-08-07 Sequitur, Inc. Double-stranded oligonucleotides
AU2003295387A1 (en) 2002-11-05 2004-06-03 Isis Parmaceuticals, Inc. Modified oligonucleotides for use in rna interference
GB0228540D0 (en) * 2002-12-06 2003-01-15 Glaxo Group Ltd Novel compositions
US20050233342A1 (en) * 2003-03-07 2005-10-20 Muthiah Manoharan Methods of preventing off-target gene silencing
WO2004113496A2 (en) 2003-06-20 2004-12-29 Isis Pharmaceuticals, Inc. Double stranded compositions comprising a 3’-endo modified strand for use in gene modulation
US20080249039A1 (en) * 2004-01-30 2008-10-09 Santaris Pharma A/S Modified Short Interfering Rna (Modified Sirna)
US8569474B2 (en) 2004-03-09 2013-10-29 Isis Pharmaceuticals, Inc. Double stranded constructs comprising one or more short strands hybridized to a longer strand
US8394947B2 (en) 2004-06-03 2013-03-12 Isis Pharmaceuticals, Inc. Positionally modified siRNA constructs
US7884086B2 (en) 2004-09-08 2011-02-08 Isis Pharmaceuticals, Inc. Conjugates for use in hepatocyte free uptake assays
WO2007068113A1 (en) * 2005-12-16 2007-06-21 Mcgill University 4'-thioarabinonucleotide-containing oligonucleotides, compounds and methods for their preparation and uses thereof
CA2638837A1 (en) * 2006-01-27 2007-08-02 Santaris Pharma A/S Lna modified phosphorothiolated oligonucleotides
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EP1606406A2 (en) 2005-12-21
ES2332178T5 (es) 2014-02-04
AU2004221760B2 (en) 2010-03-18
JP2006520760A (ja) 2006-09-14
CA2519860C (en) 2018-01-16
DE602004023279D1 (de) 2009-11-05
ES2576677T3 (es) 2016-07-08
US9297010B2 (en) 2016-03-29
US8653252B2 (en) 2014-02-18
US20140235844A1 (en) 2014-08-21
AU2004221760A1 (en) 2004-09-30
US20070191294A1 (en) 2007-08-16
JP4755972B2 (ja) 2011-08-24
EP1606406B2 (en) 2013-11-27
CA2519860A1 (en) 2004-09-30
EP1606406B1 (en) 2009-09-23

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