DK1692271T4 - Hidtil ukendte vombakterievarianter og fremgangsmåde til fremstilling af ravsyre ved anvendelse deraf - Google Patents
Hidtil ukendte vombakterievarianter og fremgangsmåde til fremstilling af ravsyre ved anvendelse deraf Download PDFInfo
- Publication number
- DK1692271T4 DK1692271T4 DK04734158.1T DK04734158T DK1692271T4 DK 1692271 T4 DK1692271 T4 DK 1692271T4 DK 04734158 T DK04734158 T DK 04734158T DK 1692271 T4 DK1692271 T4 DK 1692271T4
- Authority
- DK
- Denmark
- Prior art keywords
- succinic acid
- gene
- producing
- bacterial
- ldha
- Prior art date
Links
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 title abstract 9
- 239000001384 succinic acid Substances 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 5
- 101100398785 Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R) ldhD gene Proteins 0.000 abstract 3
- 101100386830 Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) ddh gene Proteins 0.000 abstract 3
- 101150026107 ldh1 gene Proteins 0.000 abstract 3
- 101150041530 ldha gene Proteins 0.000 abstract 3
- 241001293415 Mannheimia Species 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- 235000005985 organic acids Nutrition 0.000 abstract 2
- 210000004767 rumen Anatomy 0.000 abstract 2
- 108010092060 Acetate kinase Proteins 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 108700023483 L-lactate dehydrogenases Proteins 0.000 abstract 1
- 101100433987 Latilactobacillus sakei subsp. sakei (strain 23K) ackA1 gene Proteins 0.000 abstract 1
- 108700023175 Phosphate acetyltransferases Proteins 0.000 abstract 1
- 108091000041 Phosphoenolpyruvate Carboxylase Proteins 0.000 abstract 1
- 101150006213 ackA gene Proteins 0.000 abstract 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 abstract 1
- 108010008221 formate C-acetyltransferase Proteins 0.000 abstract 1
- 238000009776 industrial production Methods 0.000 abstract 1
- 230000037353 metabolic pathway Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020030084934A KR100556099B1 (ko) | 2003-11-27 | 2003-11-27 | 루멘 박테리아 변이균주 및 이를 이용한 숙신산의 제조방법 |
| KR1020040028105A KR100630819B1 (ko) | 2004-04-23 | 2004-04-23 | 신규 루멘 박테리아 변이균주 및 이를 이용한 숙신산의제조방법 |
| PCT/KR2004/001210 WO2005052135A1 (en) | 2003-11-27 | 2004-05-20 | Novel rumen bacteria variants and process for preparing succinic acid employing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK1692271T3 DK1692271T3 (da) | 2009-10-19 |
| DK1692271T4 true DK1692271T4 (da) | 2022-09-26 |
Family
ID=36609129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04734158.1T DK1692271T4 (da) | 2003-11-27 | 2004-05-20 | Hidtil ukendte vombakterievarianter og fremgangsmåde til fremstilling af ravsyre ved anvendelse deraf |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7470530B2 (da) |
| EP (1) | EP1692271B2 (da) |
| JP (2) | JP4672671B2 (da) |
| AT (1) | ATE439427T1 (da) |
| AU (1) | AU2004292642B2 (da) |
| BR (1) | BRPI0416437A (da) |
| CA (1) | CA2545363C (da) |
| DE (1) | DE602004022584D1 (da) |
| DK (1) | DK1692271T4 (da) |
| NZ (1) | NZ547305A (da) |
| RU (1) | RU2376369C2 (da) |
| WO (1) | WO2005052135A1 (da) |
Families Citing this family (42)
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| KR100727054B1 (ko) | 2005-08-19 | 2007-06-12 | 한국과학기술원 | 푸마레이트 하이드라타제 ｃ를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법 |
| KR100676160B1 (ko) | 2005-08-19 | 2007-02-01 | 한국과학기술원 | 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법 |
| KR100679638B1 (ko) | 2005-08-19 | 2007-02-06 | 한국과학기술원 | 포메이트 디하이드로게나제 ｄ 또는 ｅ를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법 |
| CN1321185C (zh) * | 2005-12-20 | 2007-06-13 | 哈尔滨工业大学 | 乙酸激酶基因 |
| CN100432215C (zh) * | 2006-01-24 | 2008-11-12 | 江南大学 | 一种微生物发酵生产丁二酸的菌种和方法 |
| KR100957772B1 (ko) | 2006-03-23 | 2010-05-12 | 주식회사 엘지화학 | ４―ｈｙｄｒｏｘｙｂｕｔｙｒａｔｅ（４ＨＢ）생성능을가지는 변이체 및 이를 이용한 ４ＨＢ의 제조방법 |
| KR100762962B1 (ko) | 2006-05-04 | 2007-10-04 | 한국과학기술원 | 게놈정보 및 인실리코 분석을 이용한 배양배지의 제조방법 |
| KR100780324B1 (ko) | 2006-07-28 | 2007-11-29 | 한국과학기술원 | 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법 |
| US7646297B2 (en) | 2006-12-15 | 2010-01-12 | At&T Intellectual Property I, L.P. | Context-detected auto-mode switching |
| CN105936887A (zh) | 2007-03-16 | 2016-09-14 | 基因组股份公司 | 用于1,4-丁二醇和其前体生物合成的组合物和方法 |
| EP2149608A4 (en) | 2007-04-16 | 2013-02-20 | Ajinomoto Kk | PROCESS FOR PREPARING AN ORGANIC ACID |
| EP2147970B1 (en) | 2007-04-17 | 2014-12-31 | Ajinomoto Co., Inc. | A method for producing an acidic substance having a carboxyl group |
| JP2010187542A (ja) * | 2007-06-14 | 2010-09-02 | Ajinomoto Co Inc | 有機酸の製造方法 |
| KR101103839B1 (ko) * | 2007-07-12 | 2012-01-06 | 한국과학기술원 | 순수 숙신산 생성 변이균주 및 이를 이용한 숙신산제조방법 |
| CN103589662A (zh) * | 2007-08-17 | 2014-02-19 | 巴斯夫欧洲公司 | 巴斯德氏菌科的羧酸产生成员 |
| KR101042242B1 (ko) | 2007-09-07 | 2011-06-17 | 한국과학기술원 | 1,4-부탄디올 생성능을 가지는 변이체 및 이를 이용한1,4-부탄디올의 제조방법 |
| JP5644108B2 (ja) | 2007-12-06 | 2014-12-24 | 味の素株式会社 | 有機酸の製造方法 |
| EP2334800B1 (en) * | 2008-09-10 | 2018-12-26 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol |
| ES2560534T3 (es) | 2008-12-23 | 2016-02-19 | Basf Se | Células bacterianas que muestran actividad de formato deshidrogenasa para la fabricación de ácido succínico |
| ES2559385T3 (es) | 2008-12-23 | 2016-02-11 | Basf Se | Células bacterianas que tienen una derivación de glioxilato para la fabricación de ácido succínico |
| KR101093199B1 (ko) | 2009-02-12 | 2011-12-12 | 한국과학기술원 | 글리세롤 대사능력 및 숙신산 생산능력이 향상된 재조합 미생물 및 이를 이용한 숙신산의 제조방법 |
| KR101823695B1 (ko) * | 2009-02-16 | 2018-03-14 | 바스프 에스이 | 신규 미생물 숙신산 생산자 및 숙신산의 정제 |
| US8129169B2 (en) | 2009-06-04 | 2012-03-06 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol and related methods |
| WO2011066076A1 (en) | 2009-11-25 | 2011-06-03 | Genomatica, Inc. | Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone |
| KR101221557B1 (ko) * | 2010-08-30 | 2013-01-14 | 한국과학기술원 | 수크로오즈와 글리세롤을 동시에 이용하는 신규 숙신산 생성 변이 미생물 및 이를 이용한 숙신산 제조방법 |
| KR20160116352A (ko) | 2011-07-22 | 2016-10-07 | 미리안트 코포레이션 | 유기산으로의 글리세롤의 발효 |
| CN102732449B (zh) * | 2012-04-25 | 2013-05-22 | 南京工业大学 | 产琥珀酸放线杆菌菌株yh123及其应用 |
| WO2013184602A2 (en) | 2012-06-04 | 2013-12-12 | Genomatica, Inc. | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds |
| US9657316B2 (en) | 2012-08-27 | 2017-05-23 | Genomatica, Inc. | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 1,4-butanediol related thereto |
| US11535874B2 (en) | 2012-10-22 | 2022-12-27 | Genomatica, Inc. | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing succinate related thereto |
| CN104995293A (zh) | 2012-12-17 | 2015-10-21 | 基因组股份公司 | 用于在甲醇的存在下提高还原当量的可用性,以及用于生产与此有关的己二酸、6-氨基己酸、六亚甲基二胺或己内酰胺的微生物体和方法 |
| JP2014150747A (ja) * | 2013-02-06 | 2014-08-25 | Sekisui Chem Co Ltd | 変異微生物、並びに、コハク酸の生産方法 |
| JP2016165225A (ja) | 2013-07-09 | 2016-09-15 | 味の素株式会社 | 有用物質の製造方法 |
| ES2731335T3 (es) | 2014-02-07 | 2019-11-15 | Basf Se | Microorganismos mejorados para la producción de ácido succínico |
| US10273485B2 (en) | 2014-02-07 | 2019-04-30 | Basf Se | Modified microorganism with improved biomass separation behaviour |
| JP2017505134A (ja) | 2014-02-07 | 2017-02-16 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | ショ糖における改善されたファインケミカルの生産のための改変微生物 |
| EP3119898A1 (en) | 2014-03-19 | 2017-01-25 | Basf Se | The use of glycerol with limited feed of carbohydrates for fermentation |
| JP2017216881A (ja) | 2014-12-26 | 2017-12-14 | 味の素株式会社 | ジカルボン酸の製造方法 |
| RU2631922C1 (ru) * | 2016-12-02 | 2017-09-28 | Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Национального исследовательского центра "Курчатовский институт" (НИЦ "Курчатовский институт" - ГосНИИгенетика) | Штамм дрожжей Yarrowia lipolytica - продуцент янтарной кислоты (варианты) |
| US10393371B2 (en) | 2016-12-30 | 2019-08-27 | Whirlpool Corporation | Gas burner |
| JP7158107B2 (ja) | 2017-05-19 | 2022-10-21 | ビーエーエスエフ ソシエタス・ヨーロピア | 有機化合物の生産方法 |
| EP3502241A1 (en) | 2017-12-21 | 2019-06-26 | Basf Se | Modified microorganism for improved production of succinate |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3783081T2 (de) * | 1986-06-11 | 1993-04-15 | Michigan Biotech Inst | Verfahren zur herstellung von bernsteinsaeure durch anaerobe fermentation. |
| US5521075A (en) * | 1994-12-19 | 1996-05-28 | Michigan Biotechnology Institute | Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants |
| US5770435A (en) * | 1995-11-02 | 1998-06-23 | University Of Chicago | Mutant E. coli strain with increased succinic acid production |
| RU2119536C1 (ru) * | 1997-01-21 | 1998-09-27 | Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Штамм escherichia coli - продуцент l-гистидина |
| KR19990013007A (ko) | 1997-07-31 | 1999-02-25 | 박원훈 | 형질전환된 대장균 ｓｓ373(ｋｃｔｃ 8818ｐ)과 이를 이용한숙신산의 생산방법 |
| JP4074365B2 (ja) | 1998-01-28 | 2008-04-09 | 三菱化学株式会社 | ラクテートデヒドロゲナーゼ遺伝子及び該遺伝子破壊株 |
| KR100372218B1 (ko) | 2000-06-29 | 2003-02-14 | 바이오인포메틱스 주식회사 | 유기산을 생산하는 균주 및 이를 이용한 유기산의 생산방법 |
-
2004
- 2004-05-20 WO PCT/KR2004/001210 patent/WO2005052135A1/en not_active Ceased
- 2004-05-20 AT AT04734158T patent/ATE439427T1/de not_active IP Right Cessation
- 2004-05-20 EP EP04734158.1A patent/EP1692271B2/en not_active Expired - Lifetime
- 2004-05-20 DE DE602004022584T patent/DE602004022584D1/de not_active Expired - Lifetime
- 2004-05-20 RU RU2006122804/13A patent/RU2376369C2/ru active
- 2004-05-20 DK DK04734158.1T patent/DK1692271T4/da active
- 2004-05-20 CA CA2545363A patent/CA2545363C/en not_active Expired - Lifetime
- 2004-05-20 AU AU2004292642A patent/AU2004292642B2/en not_active Expired
- 2004-05-20 BR BRPI0416437-7A patent/BRPI0416437A/pt not_active Application Discontinuation
- 2004-05-20 US US10/580,556 patent/US7470530B2/en not_active Expired - Lifetime
- 2004-05-20 NZ NZ547305A patent/NZ547305A/en not_active IP Right Cessation
- 2004-05-20 JP JP2006541014A patent/JP4672671B2/ja not_active Expired - Lifetime
-
2010
- 2010-07-23 JP JP2010165726A patent/JP2010263911A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2545363C (en) | 2011-11-15 |
| RU2006122804A (ru) | 2008-01-10 |
| JP2010263911A (ja) | 2010-11-25 |
| AU2004292642A1 (en) | 2005-06-09 |
| WO2005052135A1 (en) | 2005-06-09 |
| CA2545363A1 (en) | 2005-06-09 |
| EP1692271A4 (en) | 2007-08-08 |
| EP1692271B1 (en) | 2009-08-12 |
| JP2007512015A (ja) | 2007-05-17 |
| AU2004292642B2 (en) | 2008-02-07 |
| NZ547305A (en) | 2009-05-31 |
| DE602004022584D1 (de) | 2009-09-24 |
| JP4672671B2 (ja) | 2011-04-20 |
| EP1692271A1 (en) | 2006-08-23 |
| BRPI0416437A (pt) | 2007-02-21 |
| US20070054387A1 (en) | 2007-03-08 |
| US7470530B2 (en) | 2008-12-30 |
| RU2376369C2 (ru) | 2009-12-20 |
| EP1692271B2 (en) | 2022-08-03 |
| DK1692271T3 (da) | 2009-10-19 |
| ATE439427T1 (de) | 2009-08-15 |
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