DK1663291T3 - Rekombinante lubricinmolekyler og anvendelser deraf - Google Patents

Rekombinante lubricinmolekyler og anvendelser deraf

Info

Publication number: DK1663291T3
Authority: DK; Denmark
Prior art keywords: recombinant lubricin; lubricin molecules; molecules; recombinant; lubricin
Prior art date: 2003-08-14

Application number

DK04781229.2T

Other languages

English (en)

Inventor

Carl Ralph Flannery

Christopher John Corcoran

Bethany Annis Freeman

Lisa Anne Racie

Original Assignee

Wyeth Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-08-14

Filing date

2004-08-13

Publication date

2012-07-02

2004-08-13 Application filed by Wyeth Llc filed Critical Wyeth Llc

2012-07-02 Application granted granted Critical

2012-07-02 Publication of DK1663291T3 publication Critical patent/DK1663291T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Immunology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Physical Education & Sports Medicine (AREA)
Marine Sciences & Fisheries (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK04781229.2T 2003-08-14 2004-08-13 Rekombinante lubricinmolekyler og anvendelser deraf DK1663291T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US49574103P	2003-08-14	2003-08-14
PCT/US2004/026508 WO2005016130A2 (en)	2003-08-14	2004-08-13	Recombinant lubricin molecules and uses thereof

Publications (1)

Publication Number	Publication Date
DK1663291T3 true DK1663291T3 (da)	2012-07-02

Family

ID=34193342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04781229.2T DK1663291T3 (da)	2003-08-14	2004-08-13	Rekombinante lubricinmolekyler og anvendelser deraf

Country Status (20)

Country	Link
US (6)	US7642236B2 (da)
EP (1)	EP1663291B1 (da)
JP (1)	JP2007502122A (da)
KR (1)	KR101078202B1 (da)
CN (2)	CN102924584A (da)
AU (2)	AU2004264970B2 (da)
BR (1)	BRPI0413553A (da)
CR (1)	CR8204A (da)
DK (1)	DK1663291T3 (da)
EC (1)	ECSP066364A (da)
ES (1)	ES2388970T3 (da)
IL (2)	IL173258A (da)
MX (1)	MXPA06001658A (da)
NO (1)	NO20060475L (da)
NZ (1)	NZ545021A (da)
RU (2)	RU2376313C2 (da)
SG (1)	SG145724A1 (da)
UA (1)	UA91818C2 (da)
WO (1)	WO2005016130A2 (da)
ZA (1)	ZA200601291B (da)

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US6743774B1 (en)	1999-04-23	2004-06-01	Rhode Island Hospital	Tribonectins
JP2008507553A (ja) *	2004-07-23	2008-03-13	ミューコサルセラピューティクスリミテッドライアビリディカンパニー	粘性補給のための組成物および方法
US20090068247A1 (en) *	2007-09-12	2009-03-12	Mucosal Therapeutics	Biocompatible devices coated with a tribonectin and methods for their production
US20090104148A1 (en) *	2007-09-18	2009-04-23	Jay Gregory D	Treatment and prevention of joint disease
US8506944B2 (en) *	2008-05-07	2013-08-13	The Regents Of The University Of California	Replenishment and enrichment of ocular surface lubrication
SI2285364T1 (sl) *	2008-05-07	2015-03-31	The Regents Of The University Of California	Terapevtska regeneracija in obogatitev lubrikacije okularne povrĹˇine
ES2534082T3 (es) *	2009-01-13	2015-04-17	Lubris Llc	Modulación terapéutica de la lubricación del límite del epitelio vaginal
ES2532526T3 (es) *	2009-05-22	2015-03-27	Lubris, Llc	Aplicación y usos de PRG4 y modulación terapéutica de la misma
EP2525805B1 (en) *	2010-01-19	2017-03-15	Lubris LLC	Oral care compositions and methods
US8716204B2 (en)	2010-07-27	2014-05-06	Zimmer, Inc.	Synthetic synovial fluid compositions and methods for making the same
US20130116186A1 (en) *	2011-10-04	2013-05-09	Rhode Island Hospital, A Lifespan Partner	Lubricin injections to maintain cartilage health
DK2948553T3 (da) *	2013-01-25	2020-06-29	Baylor College Medicine	Hjælper-afhængigt afgivelses- og ekspressionssystem til adenoviral genterapi
US20150010606A1 (en) *	2013-07-08	2015-01-08	Arthrex, Inc.	Intra-articular injection and implant attachment of molecule consisting of lubricin and extracellular superoxide dismutase or hyaluronic acid and extracellular superoxide dismutase
US20160263217A1 (en) *	2013-10-16	2016-09-15	Ensisheim Partners Llc	Protein-specific formulations
US9982027B2 (en) *	2013-10-22	2018-05-29	Lubris Llc	Control of rheological properties of mixed hyaluronate/lubricin solutions
US10500250B2 (en)	2013-11-26	2019-12-10	Lubris Llc	Compositions and methods for inhibiting intercellular interactions
TN2017000270A1 (en) *	2015-01-26	2018-10-19	Lubris Llc	Use of prg4 as an anti-inflammatory agent
CN118048321A (zh) *	2016-01-13	2024-05-17	建新公司	用于治疗哺乳动物内骨关节炎和相关关节病症的表达骨保护性基因、包括has2和润滑素的重组aav载体
ES2823173T3 (es)	2016-01-27	2021-05-06	Just Biotherapeutics Inc	Promotor híbrido y usos del mismo
EP3810181A4 (en) *	2018-06-21	2022-03-30	Lubris LLC	Lubricin for use in wound healing
CN113905753A (zh) *	2019-01-15	2022-01-07	康奈尔大学	重组粘蛋白和组合物以及其使用方法
US20230127949A1 (en) *	2020-02-24	2023-04-27	Novartis Ag	Purification of recombinantly produced polypeptides
IT202000022636A1 (it)	2020-09-25	2022-03-25	Ente Ospedaliero Specializzato In Gastroenterologia Istituto Nazionale Di Ricovero E Cura A Caratter	“terapia di combinazione di sorafenib e/o regorafenib con la proteina ricombinante umana proteoglicano-4 per il trattamento dell'epatocarcinoma”

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CN1107891A (zh)	1994-03-04	1995-09-06	上海贝特生物技术有限公司	人促巨核细胞生成素及其分离纯化和基因克隆方法及应用
US5709020A (en) *	1994-07-19	1998-01-20	University Of Kentucky Research Foundation	Method for reducing the generation of wear particulates from an implant
US5515590A (en) *	1994-07-19	1996-05-14	University Of Kentucky Research Foundation	Method for reducing the generation of wear particulates from an implant
US5510122A (en) *	1994-09-28	1996-04-23	The Research Foundation Of State University Of New York	Preparation and use of whole saliva
US6743774B1 (en) *	1999-04-23	2004-06-01	Rhode Island Hospital	Tribonectins
US7001881B1 (en) *	1999-04-23	2006-02-21	Rhode Island Hospital	Tribonectins
US6960562B2 (en) *	1999-04-23	2005-11-01	Rhode Island Hospital, A Lifespan Partner	Tribonectin polypeptides and uses thereof
WO2001007068A1 (en) *	1999-07-23	2001-02-01	Case Western Reserve University	Novel methods and reagents for the treatment of osteoarthritis
EP1347993A2 (en) *	2000-12-29	2003-10-01	Glaxo Group Limited	Superficial zone protein and methods of making and using same
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2004
- 2004-08-13 DK DK04781229.2T patent/DK1663291T3/da active
- 2004-08-13 CN CN2012104146501A patent/CN102924584A/zh active Pending
- 2004-08-13 MX MXPA06001658A patent/MXPA06001658A/es active IP Right Grant
- 2004-08-13 BR BRPI0413553-9A patent/BRPI0413553A/pt not_active IP Right Cessation
- 2004-08-13 RU RU2006107925/13A patent/RU2376313C2/ru not_active IP Right Cessation
- 2004-08-13 UA UAA200602706A patent/UA91818C2/ru unknown
- 2004-08-13 EP EP04781229A patent/EP1663291B1/en not_active Expired - Lifetime
- 2004-08-13 WO PCT/US2004/026508 patent/WO2005016130A2/en not_active Ceased
- 2004-08-13 CN CNA2004800299041A patent/CN1867350A/zh active Pending
- 2004-08-13 NZ NZ545021A patent/NZ545021A/en not_active IP Right Cessation
- 2004-08-13 AU AU2004264970A patent/AU2004264970B2/en not_active Ceased
- 2004-08-13 ES ES04781229T patent/ES2388970T3/es not_active Expired - Lifetime
- 2004-08-13 SG SG200805896-8A patent/SG145724A1/en unknown
- 2004-08-13 KR KR1020067003110A patent/KR101078202B1/ko not_active Expired - Fee Related
- 2004-08-13 JP JP2006523436A patent/JP2007502122A/ja active Pending
- 2004-08-13 US US10/567,764 patent/US7642236B2/en not_active Expired - Fee Related
2006
- 2006-01-19 CR CR8204A patent/CR8204A/es unknown
- 2006-01-19 IL IL173258A patent/IL173258A/en not_active IP Right Cessation
- 2006-01-30 NO NO20060475A patent/NO20060475L/no not_active Application Discontinuation
- 2006-02-13 ZA ZA200601291A patent/ZA200601291B/xx unknown
- 2006-02-14 EC EC2006006364A patent/ECSP066364A/es unknown
2009
- 2009-06-24 IL IL199528A patent/IL199528A/en not_active IP Right Cessation
- 2009-08-07 RU RU2009130434/10A patent/RU2009130434A/ru not_active Application Discontinuation
- 2009-11-19 US US12/622,141 patent/US7893029B2/en not_active Expired - Fee Related
- 2009-11-23 US US12/624,112 patent/US7897571B2/en not_active Expired - Fee Related
2010
- 2010-04-16 AU AU2010201537A patent/AU2010201537B2/en not_active Ceased
2011
- 2011-02-25 US US13/035,529 patent/US8420793B2/en not_active Expired - Fee Related
2013
- 2013-03-08 US US13/791,346 patent/US8987205B2/en not_active Expired - Fee Related
2015
- 2015-02-05 US US14/614,809 patent/US20150343019A1/en not_active Abandoned

Also Published As

Publication number	Publication date
IL173258A (en)	2010-12-30
CR8204A (es)	2007-10-01
IL199528A0 (en)	2011-08-01
HK1089110A1 (en)	2006-11-24
RU2006107925A (ru)	2006-07-27
AU2010201537A1 (en)	2010-05-06
EP1663291A2 (en)	2006-06-07
US20100080848A1 (en)	2010-04-01
US20130196930A1 (en)	2013-08-01
EP1663291A4 (en)	2009-08-05
WO2005016130A3 (en)	2006-02-02
US8420793B2 (en)	2013-04-16
KR101078202B1 (ko)	2011-11-01
ZA200601291B (en)	2010-08-25
WO2005016130A2 (en)	2005-02-24
NZ545021A (en)	2009-03-31
US7893029B2 (en)	2011-02-22
AU2010201537B2 (en)	2012-02-23
CN102924584A (zh)	2013-02-13
CN1867350A (zh)	2006-11-22
ES2388970T3 (es)	2012-10-22
IL199528A (en)	2013-03-24
US8987205B2 (en)	2015-03-24
IL173258A0 (en)	2006-06-11
AU2004264970A1 (en)	2005-02-24
EP1663291B1 (en)	2012-06-06
US7642236B2 (en)	2010-01-05
SG145724A1 (en)	2008-09-29
US20070191268A1 (en)	2007-08-16
NO20060475L (no)	2006-03-13
AU2004264970B2 (en)	2010-02-11
RU2009130434A (ru)	2011-02-20
US7897571B2 (en)	2011-03-01
US20100074935A1 (en)	2010-03-25
BRPI0413553A (pt)	2006-10-17
UA91818C2 (ru)	2010-09-10
ECSP066364A (es)	2006-08-30
RU2376313C2 (ru)	2009-12-20
US20150343019A1 (en)	2015-12-03
KR20060072124A (ko)	2006-06-27
MXPA06001658A (es)	2006-04-28
JP2007502122A (ja)	2007-02-08
US20110189731A1 (en)	2011-08-04

Publication	Publication Date	Title
DK1663291T3 (da)	2012-07-02	Rekombinante lubricinmolekyler og anvendelser deraf
CY2018009I2 (el)	2018-06-27	Παραλλαγες ανοσοσφαιρινων και χρησεις αυτων
DK1641822T3 (da)	2013-07-22	Heterologe il-17-a/f-polypeptider og terapeutiske anvendelser deraf.
DK1680443T3 (da)	2013-12-16	Stabiliserede alfa-helix-peptider og anvendelser heraf
DK1711207T3 (da)	2013-03-11	Interferon-alpha-antistoffer og anvendelse heraf
DK1404809T3 (da)	2014-03-17	Forbedrede hudsubstitutter og anvendelser deraf
DK1513873T3 (da)	2014-11-03	Terapeutiske epitoper og anvendelser deraf
DK1673460T3 (da)	2013-02-04	Rekombinante vacciner og anvendelse af disse
ATE486091T1 (de)	2010-11-15	Vegf-fallen und therapeutische verwendungen dafür
NO20055568D0 (no)	2005-11-24	Substituerte 1,4-diazepiner og anvendelser derav
DE60326145D1 (de)	2009-03-26	Spielermittlungsverfahren
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