NO20060475L - Rekombinant lubricinmolekyler og anvendelser derav - Google Patents
Rekombinant lubricinmolekyler og anvendelser deravInfo
- Publication number
- NO20060475L NO20060475L NO20060475A NO20060475A NO20060475L NO 20060475 L NO20060475 L NO 20060475L NO 20060475 A NO20060475 A NO 20060475A NO 20060475 A NO20060475 A NO 20060475A NO 20060475 L NO20060475 L NO 20060475L
- Authority
- NO
- Norway
- Prior art keywords
- applications
- recombinant lubricin
- lubricin molecules
- molecules
- recombinant
- Prior art date
Links
- 102100028965 Proteoglycan 4 Human genes 0.000 title abstract 3
- 108010009030 lubricin Proteins 0.000 title abstract 3
- 210000001503 joint Anatomy 0.000 abstract 2
- 230000000181 anti-adherent effect Effects 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 230000005499 meniscus Effects 0.000 abstract 1
- 210000003516 pericardium Anatomy 0.000 abstract 1
- 210000004303 peritoneum Anatomy 0.000 abstract 1
- 210000004224 pleura Anatomy 0.000 abstract 1
- 239000013589 supplement Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Physical Education & Sports Medicine (AREA)
- Marine Sciences & Fisheries (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Rekombinant lubricinmolekyler og anvendelser derav. Nye rekombinante lubricinmolekyler og anvendelser derav som smøremidler, antiadhesive midler og eller intraartikulære supplementer for, f. eks., synovialledd, menisk, ledd, peritoneum, perikardium og pleura tilveiebringes.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49574103P | 2003-08-14 | 2003-08-14 | |
| PCT/US2004/026508 WO2005016130A2 (en) | 2003-08-14 | 2004-08-13 | Recombinant lubricin molecules and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20060475L true NO20060475L (no) | 2006-03-13 |
Family
ID=34193342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20060475A NO20060475L (no) | 2003-08-14 | 2006-01-30 | Rekombinant lubricinmolekyler og anvendelser derav |
Country Status (20)
| Country | Link |
|---|---|
| US (6) | US7642236B2 (no) |
| EP (1) | EP1663291B1 (no) |
| JP (1) | JP2007502122A (no) |
| KR (1) | KR101078202B1 (no) |
| CN (2) | CN102924584A (no) |
| AU (2) | AU2004264970B2 (no) |
| BR (1) | BRPI0413553A (no) |
| CR (1) | CR8204A (no) |
| DK (1) | DK1663291T3 (no) |
| EC (1) | ECSP066364A (no) |
| ES (1) | ES2388970T3 (no) |
| IL (2) | IL173258A (no) |
| MX (1) | MXPA06001658A (no) |
| NO (1) | NO20060475L (no) |
| NZ (1) | NZ545021A (no) |
| RU (2) | RU2376313C2 (no) |
| SG (1) | SG145724A1 (no) |
| UA (1) | UA91818C2 (no) |
| WO (1) | WO2005016130A2 (no) |
| ZA (1) | ZA200601291B (no) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6743774B1 (en) | 1999-04-23 | 2004-06-01 | Rhode Island Hospital | Tribonectins |
| JP2008507553A (ja) * | 2004-07-23 | 2008-03-13 | ミューコサル セラピューティクス リミテッド ライアビリディ カンパニー | 粘性補給のための組成物および方法 |
| US20090068247A1 (en) * | 2007-09-12 | 2009-03-12 | Mucosal Therapeutics | Biocompatible devices coated with a tribonectin and methods for their production |
| US20090104148A1 (en) * | 2007-09-18 | 2009-04-23 | Jay Gregory D | Treatment and prevention of joint disease |
| US8506944B2 (en) * | 2008-05-07 | 2013-08-13 | The Regents Of The University Of California | Replenishment and enrichment of ocular surface lubrication |
| SI2285364T1 (sl) * | 2008-05-07 | 2015-03-31 | The Regents Of The University Of California | Terapevtska regeneracija in obogatitev lubrikacije okularne površine |
| ES2534082T3 (es) * | 2009-01-13 | 2015-04-17 | Lubris Llc | Modulación terapéutica de la lubricación del límite del epitelio vaginal |
| ES2532526T3 (es) * | 2009-05-22 | 2015-03-27 | Lubris, Llc | Aplicación y usos de PRG4 y modulación terapéutica de la misma |
| EP2525805B1 (en) * | 2010-01-19 | 2017-03-15 | Lubris LLC | Oral care compositions and methods |
| US8716204B2 (en) | 2010-07-27 | 2014-05-06 | Zimmer, Inc. | Synthetic synovial fluid compositions and methods for making the same |
| US20130116186A1 (en) * | 2011-10-04 | 2013-05-09 | Rhode Island Hospital, A Lifespan Partner | Lubricin injections to maintain cartilage health |
| DK2948553T3 (da) * | 2013-01-25 | 2020-06-29 | Baylor College Medicine | Hjælper-afhængigt afgivelses- og ekspressionssystem til adenoviral genterapi |
| US20150010606A1 (en) * | 2013-07-08 | 2015-01-08 | Arthrex, Inc. | Intra-articular injection and implant attachment of molecule consisting of lubricin and extracellular superoxide dismutase or hyaluronic acid and extracellular superoxide dismutase |
| US20160263217A1 (en) * | 2013-10-16 | 2016-09-15 | Ensisheim Partners Llc | Protein-specific formulations |
| US9982027B2 (en) * | 2013-10-22 | 2018-05-29 | Lubris Llc | Control of rheological properties of mixed hyaluronate/lubricin solutions |
| US10500250B2 (en) | 2013-11-26 | 2019-12-10 | Lubris Llc | Compositions and methods for inhibiting intercellular interactions |
| TN2017000270A1 (en) * | 2015-01-26 | 2018-10-19 | Lubris Llc | Use of prg4 as an anti-inflammatory agent |
| CN118048321A (zh) * | 2016-01-13 | 2024-05-17 | 建新公司 | 用于治疗哺乳动物内骨关节炎和相关关节病症的表达骨保护性基因、包括has2和润滑素的重组aav载体 |
| ES2823173T3 (es) | 2016-01-27 | 2021-05-06 | Just Biotherapeutics Inc | Promotor híbrido y usos del mismo |
| EP3810181A4 (en) * | 2018-06-21 | 2022-03-30 | Lubris LLC | Lubricin for use in wound healing |
| CN113905753A (zh) * | 2019-01-15 | 2022-01-07 | 康奈尔大学 | 重组粘蛋白和组合物以及其使用方法 |
| US20230127949A1 (en) * | 2020-02-24 | 2023-04-27 | Novartis Ag | Purification of recombinantly produced polypeptides |
| IT202000022636A1 (it) | 2020-09-25 | 2022-03-25 | Ente Ospedaliero Specializzato In Gastroenterologia Istituto Nazionale Di Ricovero E Cura A Caratter | “terapia di combinazione di sorafenib e/o regorafenib con la proteina ricombinante umana proteoglicano-4 per il trattamento dell'epatocarcinoma” |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2734862A (en) * | 1956-02-14 | Synthetic casein fiber elastic grease | ||
| US2487377A (en) * | 1948-04-17 | 1949-11-08 | Socony Vacuum Oil Co Inc | Lubricant |
| US2878184A (en) * | 1953-12-29 | 1959-03-17 | Rockwell Mfg Co | Hydrocarbon resistant glycerol base lubricant |
| AR207237A1 (es) * | 1974-02-25 | 1976-09-22 | Thomas A | Procedimiento para obtener extractos biologicos estables liofilizados solubles constituidos por complejos proteicos termorresistentes |
| EP0050644B1 (en) * | 1980-04-25 | 1985-09-18 | A/S Orthana Kemisk Fabrik | Sterilized, preserved, stable mucine-containing solutions and sterilization method |
| US5403592A (en) * | 1987-08-25 | 1995-04-04 | Macnaught Pty Limited | Lubricant composition for rheumatism |
| GB8803697D0 (en) * | 1988-02-17 | 1988-03-16 | Deltanine Research Ltd | Clinical developments using amniotic membrane cells |
| US5510418A (en) * | 1988-11-21 | 1996-04-23 | Collagen Corporation | Glycosaminoglycan-synthetic polymer conjugates |
| US5260417A (en) * | 1989-04-03 | 1993-11-09 | Genetics Institute, Inc. | Megakaryocyte growth promoting activity protein |
| US6433142B1 (en) * | 1989-08-08 | 2002-08-13 | Genetics Institute, Llc | Megakaryocyte stimulating factors |
| US5326558A (en) * | 1989-08-08 | 1994-07-05 | Genetics Institute, Inc. | Megakaryocytopoietic factor |
| CA2060223C (en) * | 1991-02-12 | 1999-07-20 | Clarence C. Lee | Injectable medical lubricating fluid composition and method of use |
| US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
| CN1107891A (zh) | 1994-03-04 | 1995-09-06 | 上海贝特生物技术有限公司 | 人促巨核细胞生成素及其分离纯化和基因克隆方法及应用 |
| US5709020A (en) * | 1994-07-19 | 1998-01-20 | University Of Kentucky Research Foundation | Method for reducing the generation of wear particulates from an implant |
| US5515590A (en) * | 1994-07-19 | 1996-05-14 | University Of Kentucky Research Foundation | Method for reducing the generation of wear particulates from an implant |
| US5510122A (en) * | 1994-09-28 | 1996-04-23 | The Research Foundation Of State University Of New York | Preparation and use of whole saliva |
| US6743774B1 (en) * | 1999-04-23 | 2004-06-01 | Rhode Island Hospital | Tribonectins |
| US7001881B1 (en) * | 1999-04-23 | 2006-02-21 | Rhode Island Hospital | Tribonectins |
| US6960562B2 (en) * | 1999-04-23 | 2005-11-01 | Rhode Island Hospital, A Lifespan Partner | Tribonectin polypeptides and uses thereof |
| WO2001007068A1 (en) * | 1999-07-23 | 2001-02-01 | Case Western Reserve University | Novel methods and reagents for the treatment of osteoarthritis |
| EP1347993A2 (en) * | 2000-12-29 | 2003-10-01 | Glaxo Group Limited | Superficial zone protein and methods of making and using same |
| EP1440981A3 (en) * | 2003-01-21 | 2005-11-23 | Research Association for Biotechnology | Full-length human cdna |
-
2004
- 2004-08-13 DK DK04781229.2T patent/DK1663291T3/da active
- 2004-08-13 CN CN2012104146501A patent/CN102924584A/zh active Pending
- 2004-08-13 MX MXPA06001658A patent/MXPA06001658A/es active IP Right Grant
- 2004-08-13 BR BRPI0413553-9A patent/BRPI0413553A/pt not_active IP Right Cessation
- 2004-08-13 RU RU2006107925/13A patent/RU2376313C2/ru not_active IP Right Cessation
- 2004-08-13 UA UAA200602706A patent/UA91818C2/ru unknown
- 2004-08-13 EP EP04781229A patent/EP1663291B1/en not_active Expired - Lifetime
- 2004-08-13 WO PCT/US2004/026508 patent/WO2005016130A2/en not_active Ceased
- 2004-08-13 CN CNA2004800299041A patent/CN1867350A/zh active Pending
- 2004-08-13 NZ NZ545021A patent/NZ545021A/en not_active IP Right Cessation
- 2004-08-13 AU AU2004264970A patent/AU2004264970B2/en not_active Ceased
- 2004-08-13 ES ES04781229T patent/ES2388970T3/es not_active Expired - Lifetime
- 2004-08-13 SG SG200805896-8A patent/SG145724A1/en unknown
- 2004-08-13 KR KR1020067003110A patent/KR101078202B1/ko not_active Expired - Fee Related
- 2004-08-13 JP JP2006523436A patent/JP2007502122A/ja active Pending
- 2004-08-13 US US10/567,764 patent/US7642236B2/en not_active Expired - Fee Related
-
2006
- 2006-01-19 CR CR8204A patent/CR8204A/es unknown
- 2006-01-19 IL IL173258A patent/IL173258A/en not_active IP Right Cessation
- 2006-01-30 NO NO20060475A patent/NO20060475L/no not_active Application Discontinuation
- 2006-02-13 ZA ZA200601291A patent/ZA200601291B/xx unknown
- 2006-02-14 EC EC2006006364A patent/ECSP066364A/es unknown
-
2009
- 2009-06-24 IL IL199528A patent/IL199528A/en not_active IP Right Cessation
- 2009-08-07 RU RU2009130434/10A patent/RU2009130434A/ru not_active Application Discontinuation
- 2009-11-19 US US12/622,141 patent/US7893029B2/en not_active Expired - Fee Related
- 2009-11-23 US US12/624,112 patent/US7897571B2/en not_active Expired - Fee Related
-
2010
- 2010-04-16 AU AU2010201537A patent/AU2010201537B2/en not_active Ceased
-
2011
- 2011-02-25 US US13/035,529 patent/US8420793B2/en not_active Expired - Fee Related
-
2013
- 2013-03-08 US US13/791,346 patent/US8987205B2/en not_active Expired - Fee Related
-
2015
- 2015-02-05 US US14/614,809 patent/US20150343019A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |