DK1597391T3 - Anvendelse af intron-RNA til måling af genekspression - Google Patents
Anvendelse af intron-RNA til måling af genekspressionInfo
- Publication number
- DK1597391T3 DK1597391T3 DK04712947T DK04712947T DK1597391T3 DK 1597391 T3 DK1597391 T3 DK 1597391T3 DK 04712947 T DK04712947 T DK 04712947T DK 04712947 T DK04712947 T DK 04712947T DK 1597391 T3 DK1597391 T3 DK 1597391T3
- Authority
- DK
- Denmark
- Prior art keywords
- gene expression
- measure gene
- intron rna
- rna
- expression
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 5
- 238000000034 method Methods 0.000 abstract 2
- 238000011223 gene expression profiling Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44899103P | 2003-02-20 | 2003-02-20 | |
| PCT/US2004/005287 WO2004074518A1 (en) | 2003-02-20 | 2004-02-19 | Use of intronic rna to measure gene expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1597391T3 true DK1597391T3 (da) | 2009-01-12 |
Family
ID=32908682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04712947T DK1597391T3 (da) | 2003-02-20 | 2004-02-19 | Anvendelse af intron-RNA til måling af genekspression |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7767391B2 (da) |
| EP (1) | EP1597391B1 (da) |
| JP (2) | JP4568716B2 (da) |
| AT (1) | ATE412779T1 (da) |
| AU (1) | AU2004213871B9 (da) |
| CA (1) | CA2516553C (da) |
| DE (1) | DE602004017426D1 (da) |
| DK (1) | DK1597391T3 (da) |
| ES (1) | ES2314378T3 (da) |
| PT (1) | PT1597391E (da) |
| WO (1) | WO2004074518A1 (da) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1918386T3 (da) * | 2002-03-13 | 2012-01-02 | Genomic Health Inc | Genekspressionsprofiler i biopsier af tumorvæv |
| AU2003295598B2 (en) | 2002-11-15 | 2009-12-24 | Genomic Health, Inc. | Gene expression profiling of EGFR positive cancer |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| DE602004017426D1 (de) * | 2003-02-20 | 2008-12-11 | Genomic Health Inc | Benutzung von intronischen rna sequenzen zur quantifizierung der genexpression |
| CA2527285A1 (en) * | 2003-05-28 | 2004-12-23 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| ES2690168T3 (es) | 2003-06-24 | 2018-11-19 | Genomic Health, Inc. | Predicción de la probabilidad de recidiva de cáncer |
| ES2636470T3 (es) | 2004-04-09 | 2017-10-05 | Genomic Health, Inc. | Marcadores de expresión génica para predecir la respuesta a la quimioterapia |
| AU2012200431B2 (en) * | 2004-04-09 | 2013-06-27 | Fondazione Irccs Istituto Nazionale Dei Tumori | Gene expression markers for predicting response to chemotherapy |
| JP2009501531A (ja) * | 2005-07-15 | 2009-01-22 | アプレラ コーポレイション | Ｒｎａプロファイリングのための方法 |
| JP2009505658A (ja) * | 2005-08-24 | 2009-02-12 | ブリストル−マイヤーズ スクイブ カンパニー | 上皮増殖因子受容体モデュレーターに対する感受性を決定するためのバイオマーカーおよび方法 |
| EP2412823B1 (en) | 2006-01-11 | 2014-09-03 | Genomic Health, Inc. | Gene expression markers for colorectal cancer prognosis |
| WO2007123772A2 (en) | 2006-03-31 | 2007-11-01 | Genomic Health, Inc. | Genes involved in estrogen metabolism |
| CA2651995C (en) | 2006-05-18 | 2017-04-25 | Molecular Profiling Institute, Inc. | System and method for determining individualized medical intervention for a disease state |
| US8768629B2 (en) * | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| US8338109B2 (en) | 2006-11-02 | 2012-12-25 | Mayo Foundation For Medical Education And Research | Predicting cancer outcome |
| US20090125247A1 (en) * | 2007-08-16 | 2009-05-14 | Joffre Baker | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
| AU2009246398A1 (en) * | 2008-05-14 | 2009-11-19 | Bristol-Myers Squibb Company | Predictors of patient response to treatment with EGF receptor inhibitors |
| AU2009253675A1 (en) | 2008-05-28 | 2009-12-03 | Genomedx Biosciences, Inc. | Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer |
| US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
| WO2012006632A2 (en) | 2010-07-09 | 2012-01-12 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US20100221752A2 (en) * | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
| WO2010045318A2 (en) * | 2008-10-14 | 2010-04-22 | Caris Mpi, Inc. | Gene and gene expressed protein targets depicting biomarker patterns and signature sets by tumor type |
| WO2011109440A1 (en) | 2010-03-01 | 2011-09-09 | Caris Life Sciences Luxembourg Holdings | Biomarkers for theranostics |
| CN107254538A (zh) | 2008-11-12 | 2017-10-17 | 卡里斯生命科学瑞士控股有限责任公司 | 使用外来体来确定表现型的方法和系统 |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US9495515B1 (en) | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| US9074258B2 (en) | 2009-03-04 | 2015-07-07 | Genomedx Biosciences Inc. | Compositions and methods for classifying thyroid nodule disease |
| SG10201401722XA (en) * | 2009-05-01 | 2014-08-28 | Genomic Health Inc | Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer andresponse to chemotherapy |
| EP2427575B1 (en) | 2009-05-07 | 2018-01-24 | Veracyte, Inc. | Methods for diagnosis of thyroid conditions |
| US10446272B2 (en) | 2009-12-09 | 2019-10-15 | Veracyte, Inc. | Methods and compositions for classification of samples |
| US9469876B2 (en) | 2010-04-06 | 2016-10-18 | Caris Life Sciences Switzerland Holdings Gmbh | Circulating biomarkers for metastatic prostate cancer |
| EP3812469A1 (en) | 2010-07-07 | 2021-04-28 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| DE102010033575B4 (de) * | 2010-08-02 | 2016-01-14 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | ASPP2-Splicevariante |
| BR112013003391B8 (pt) | 2010-08-13 | 2022-10-25 | Somalogic Inc | Método para diagnosticar câncer pancreático em um indivíduo |
| WO2012030840A2 (en) | 2010-08-30 | 2012-03-08 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| US20130267443A1 (en) | 2010-11-19 | 2013-10-10 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| WO2012174203A2 (en) * | 2011-06-14 | 2012-12-20 | Anthony Albino | Methods and kits for the detection and treatment of recurring prostate cancer |
| EP2744916A4 (en) | 2011-07-13 | 2015-06-17 | Primeradx Inc | MULTIMODAL PROCEDURE FOR THE SIMULTANEOUS DETECTION AND QUANTIFICATION OF MULTIPLE NUCLEIC ACIDS IN ONE SAMPLE |
| GB201114919D0 (en) * | 2011-08-30 | 2011-10-12 | Glaxosmithkline Biolog Sa | Method |
| US10513737B2 (en) | 2011-12-13 | 2019-12-24 | Decipher Biosciences, Inc. | Cancer diagnostics using non-coding transcripts |
| EP3435084B1 (en) | 2012-08-16 | 2023-02-22 | Decipher Biosciences, Inc. | Prostate cancer prognostics using biomarkers |
| WO2014078700A1 (en) | 2012-11-16 | 2014-05-22 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| EP2968988A4 (en) | 2013-03-14 | 2016-11-16 | Allegro Diagnostics Corp | METHOD FOR EVALUATING A COPD STATUS |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| CA2947624A1 (en) | 2014-05-13 | 2015-11-19 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| JP7356788B2 (ja) | 2014-11-05 | 2023-10-05 | ベラサイト インコーポレイテッド | 機械学習および高次元転写データを使用して経気管支生検における特発性肺線維症を診断するシステムおよび方法 |
| EP3504348B1 (en) | 2016-08-24 | 2022-12-14 | Decipher Biosciences, Inc. | Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy |
| WO2018132916A1 (en) | 2017-01-20 | 2018-07-26 | Genomedx Biosciences, Inc. | Molecular subtyping, prognosis, and treatment of bladder cancer |
| EP3593140A4 (en) | 2017-03-09 | 2021-01-06 | Decipher Biosciences, Inc. | SUBTYPING PROSTATE CANCER TO PREDICT RESPONSE TO HORMONE THERAPY |
| WO2018205035A1 (en) | 2017-05-12 | 2018-11-15 | Genomedx Biosciences, Inc | Genetic signatures to predict prostate cancer metastasis and identify tumor agressiveness |
| US11217329B1 (en) | 2017-06-23 | 2022-01-04 | Veracyte, Inc. | Methods and systems for determining biological sample integrity |
| CA3072061A1 (en) | 2017-08-04 | 2019-02-07 | The Regents Of The University Of Michigan | Use of immune cell-specific gene expression for prognosis of prostate cancer and prediction of responsiveness to radiation therapy |
Family Cites Families (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1252046A (en) | 1982-11-04 | 1989-04-04 | Martin J. Cline | Methods for oncogenic detection |
| US4699877A (en) * | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| USRE35491E (en) * | 1982-11-04 | 1997-04-08 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| US7838216B1 (en) * | 1986-03-05 | 2010-11-23 | The United States Of America, As Represented By The Department Of Health And Human Services | Human gene related to but distinct from EGF receptor gene |
| US5015568A (en) * | 1986-07-09 | 1991-05-14 | The Wistar Institute | Diagnostic methods for detecting lymphomas in humans |
| US5202429A (en) * | 1986-07-09 | 1993-04-13 | The Wistar Institute | DNA molecules having human BCL-2 gene sequences |
| US4968603A (en) * | 1986-12-31 | 1990-11-06 | The Regents Of The University Of California | Determination of status in neoplastic disease |
| US5831066A (en) * | 1988-12-22 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Regulation of bcl-2 gene expression |
| US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| US5858678A (en) * | 1994-08-02 | 1999-01-12 | St. Louis University | Apoptosis-regulating proteins |
| US5830753A (en) * | 1994-09-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof. |
| US6416635B1 (en) * | 1995-07-24 | 2002-07-09 | Tokyo Electron Limited | Method and apparatus for sputter coating with variable target to substrate spacing |
| US6716575B2 (en) * | 1995-12-18 | 2004-04-06 | Sugen, Inc. | Diagnosis and treatment of AUR1 and/or AUR2 related disorders |
| PT868519E (pt) * | 1995-12-18 | 2006-05-31 | Sugen Inc | Diagnostico e tratamento de disturbios relacionados com aur-1 e/ou aur-2 |
| US5670325A (en) * | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
| US5741650A (en) * | 1996-01-30 | 1998-04-21 | Exact Laboratories, Inc. | Methods for detecting colon cancer from stool samples |
| US5821082A (en) * | 1996-05-23 | 1998-10-13 | St. Louis University Health Sciences Center | Anti-proliferation domain of a human Bcl-2 and DNA encoding the same |
| US6020137A (en) * | 1996-08-14 | 2000-02-01 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US6203993B1 (en) * | 1996-08-14 | 2001-03-20 | Exact Science Corp. | Methods for the detection of nucleic acids |
| US5928870A (en) * | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US5952178A (en) * | 1996-08-14 | 1999-09-14 | Exact Laboratories | Methods for disease diagnosis from stool samples |
| US6100029A (en) * | 1996-08-14 | 2000-08-08 | Exact Laboratories, Inc. | Methods for the detection of chromosomal aberrations |
| US6143529A (en) * | 1996-08-14 | 2000-11-07 | Exact Laboratories, Inc. | Methods for improving sensitivity and specificity of screening assays |
| US6146828A (en) | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
| US5861278A (en) * | 1996-11-01 | 1999-01-19 | Genetics Institute, Inc. | HNF3δ compositions |
| JP4672092B2 (ja) * | 1996-11-20 | 2011-04-20 | イェール ユニバーシティ | 細胞アポトーシスを阻害するタンパク質であるサービビン（Ｓｕｒｖｉｖｉｎ）、およびその調節 |
| US5830665A (en) * | 1997-03-03 | 1998-11-03 | Exact Laboratories, Inc. | Contiguous genomic sequence scanning |
| US6033893A (en) | 1997-06-26 | 2000-03-07 | Incyte Pharmaceuticals, Inc. | Human cathepsin |
| WO1999002714A1 (en) | 1997-07-07 | 1999-01-21 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the breast |
| US6020135A (en) * | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
| GB2339200B (en) * | 1998-06-06 | 2001-09-12 | Genostic Pharma Ltd | Genostics |
| US6696558B2 (en) * | 1998-09-09 | 2004-02-24 | The Burnham Institute | Bag proteins and nucleic acid molecules encoding them |
| WO2000050595A2 (en) | 1999-02-25 | 2000-08-31 | Ivan Gout | Nucleic acid molecules associated with melanoma and thyroid tumors |
| US20020039764A1 (en) * | 1999-03-12 | 2002-04-04 | Rosen Craig A. | Nucleic, acids, proteins, and antibodies |
| AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| US6692916B2 (en) * | 1999-06-28 | 2004-02-17 | Source Precision Medicine, Inc. | Systems and methods for characterizing a biological condition or agent using precision gene expression profiles |
| US6960439B2 (en) * | 1999-06-28 | 2005-11-01 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| US6326148B1 (en) | 1999-07-12 | 2001-12-04 | The Regents Of The University Of California | Detection of copy number changes in colon cancer |
| US6710170B2 (en) * | 1999-09-10 | 2004-03-23 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
| US6271002B1 (en) * | 1999-10-04 | 2001-08-07 | Rosetta Inpharmatics, Inc. | RNA amplification method |
| WO2001025250A1 (en) | 1999-10-06 | 2001-04-12 | The Regents Of The University Of California | Differentially expressed genes associated with her-2/neu overexpression |
| EP1690872A3 (en) | 1999-12-01 | 2006-08-23 | Genentech, Inc. | Composition and methods for the diagnosis of tumours |
| US6750013B2 (en) * | 1999-12-02 | 2004-06-15 | Protein Design Labs, Inc. | Methods for detection and diagnosing of breast cancer |
| US6248535B1 (en) * | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
| EP1276901A2 (en) * | 2000-01-13 | 2003-01-22 | Amsterdam Support Diagnostics B.V. | A universal nucleic acid amplification system for nucleic acids in a sample |
| US6322986B1 (en) * | 2000-01-18 | 2001-11-27 | Albany Medical College | Method for colorectal cancer prognosis and treatment selection |
| WO2001055454A1 (en) * | 2000-01-28 | 2001-08-02 | Althea Technologies, Inc. | Methods for analysis of gene expression |
| AU2001241408A1 (en) | 2000-01-31 | 2001-08-07 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| US20030165831A1 (en) | 2000-03-21 | 2003-09-04 | John Lee | Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of ovarian cancer |
| AU2001249600A1 (en) * | 2000-03-31 | 2001-10-15 | University Of Louisville Research Foundation, Inc. | Microarrays to screen regulatory genes |
| WO2002000677A1 (en) | 2000-06-07 | 2002-01-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| JP2004504059A (ja) * | 2000-07-21 | 2004-02-12 | グローバル ジェノミクス アクティエボラーグ | 転写された遺伝子を分析、及び同定するための方法、及びフインガープリント法 |
| US7118853B2 (en) | 2000-07-26 | 2006-10-10 | Applied Genomics, Inc. | Methods of classifying, diagnosing, stratifying and treating cancer patients and their tumors |
| WO2002008260A2 (en) | 2000-07-26 | 2002-01-31 | Stanford University | Bstp-ecg1 protein and related reagents and methods of use thereof |
| AU2001277202A1 (en) | 2000-07-26 | 2002-02-05 | Applied Genomics, Inc. | Bstp-ras/rerg protein and related reagents and methods of use thereof |
| US7795232B1 (en) | 2000-08-25 | 2010-09-14 | Genta Incorporated | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
| US6582919B2 (en) * | 2001-06-11 | 2003-06-24 | Response Genetics, Inc. | Method of determining epidermal growth factor receptor and HER2-neu gene expression and correlation of levels thereof with survival rates |
| US6602670B2 (en) * | 2000-12-01 | 2003-08-05 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 expression |
| AU2002234799A1 (en) | 2000-12-08 | 2002-06-18 | Ipsogen | Gene expression profiling of primary breast carcinomas using arrays of candidate genes |
| AU2002255478A1 (en) | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| AU2002246970B2 (en) * | 2001-01-12 | 2007-06-14 | Yale University | Detection of survivin in the biological fluids of cancer patients |
| US7776518B2 (en) * | 2001-01-12 | 2010-08-17 | Yale University | Detection of survivin in the biological fluids of cancer patients |
| AU2002245317A1 (en) | 2001-01-24 | 2002-08-06 | Protein Design Labs | Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer |
| US20030199685A1 (en) * | 2001-03-12 | 2003-10-23 | Monogen, Inc. | Cell-based detection and differentiation of disease states |
| JP2005500832A (ja) | 2001-06-18 | 2005-01-13 | ロゼッタ・インファーマティクス・インコーポレーテッド | 乳癌患者の診断および予後 |
| WO2003011897A1 (en) | 2001-07-27 | 2003-02-13 | The Regents Of The University Of California | Modulation of heregulin and her3 interaction |
| US7026123B1 (en) * | 2001-08-29 | 2006-04-11 | Pioneer Hi-Bred International, Inc. | UTR tag assay for gene function discovery |
| US20040009489A1 (en) * | 2001-09-28 | 2004-01-15 | Golub Todd R. | Classification of lung carcinomas using gene expression analysis |
| CN102402650A (zh) * | 2001-11-09 | 2012-04-04 | 生命技术公司 | 利用基因表达分布图识别、监控和治疗疾病以及鉴定生物学状态 |
| US20030198972A1 (en) * | 2001-12-21 | 2003-10-23 | Erlander Mark G. | Grading of breast cancer |
| CA2480635A1 (en) | 2002-03-28 | 2003-10-09 | Allen D. Delaney | Cancer associated protein kinases and their uses |
| EP1900827A3 (en) | 2002-05-21 | 2008-04-16 | Bayer HealthCare AG | Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia |
| DE602004017426D1 (de) * | 2003-02-20 | 2008-12-11 | Genomic Health Inc | Benutzung von intronischen rna sequenzen zur quantifizierung der genexpression |
-
2004
- 2004-02-19 DE DE602004017426T patent/DE602004017426D1/de not_active Expired - Lifetime
- 2004-02-19 JP JP2006503799A patent/JP4568716B2/ja not_active Expired - Lifetime
- 2004-02-19 AU AU2004213871A patent/AU2004213871B9/en not_active Expired
- 2004-02-19 AT AT04712947T patent/ATE412779T1/de active
- 2004-02-19 EP EP04712947A patent/EP1597391B1/en not_active Expired - Lifetime
- 2004-02-19 DK DK04712947T patent/DK1597391T3/da active
- 2004-02-19 PT PT04712947T patent/PT1597391E/pt unknown
- 2004-02-19 ES ES04712947T patent/ES2314378T3/es not_active Expired - Lifetime
- 2004-02-19 US US10/783,884 patent/US7767391B2/en not_active Expired - Lifetime
- 2004-02-19 CA CA2516553A patent/CA2516553C/en not_active Expired - Lifetime
- 2004-02-19 WO PCT/US2004/005287 patent/WO2004074518A1/en not_active Ceased
-
2006
- 2006-12-25 JP JP2006348657A patent/JP2007075127A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE602004017426D1 (de) | 2008-12-11 |
| US20040191817A1 (en) | 2004-09-30 |
| US7767391B2 (en) | 2010-08-03 |
| CA2516553A1 (en) | 2004-09-02 |
| AU2004213871B9 (en) | 2009-09-03 |
| ATE412779T1 (de) | 2008-11-15 |
| AU2004213871A1 (en) | 2004-09-02 |
| CA2516553C (en) | 2013-04-16 |
| AU2004213871B2 (en) | 2009-01-29 |
| ES2314378T3 (es) | 2009-03-16 |
| WO2004074518A1 (en) | 2004-09-02 |
| PT1597391E (pt) | 2008-12-19 |
| EP1597391A1 (en) | 2005-11-23 |
| JP4568716B2 (ja) | 2010-10-27 |
| JP2007075127A (ja) | 2007-03-29 |
| EP1597391B1 (en) | 2008-10-29 |
| JP2006518602A (ja) | 2006-08-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1597391T3 (da) | Anvendelse af intron-RNA til måling af genekspression | |
| DK1735459T3 (da) | Fremgangsmåder til kvantificering af microRNA'er og små interfererende RNA'er | |
| ATE527385T1 (de) | Mit tumoren assoziierte genetische variationen | |
| WO2006137941A3 (en) | Methods and compositions involving mirna and mirna inhibitor molecules | |
| ATE444377T1 (de) | Nukleinsäurecharakterisierung | |
| EP2037737A4 (en) | PROTEINS, NUCLEIC ACIDS FOR THEIR CODING AND CORRESPONDING USES. | |
| EP2253713A4 (en) | METHOD FOR MEASURING COPY COUNTS OF CHROMOSOMES, GENES OR SPECIFIC NUCLEOTIDE SEQUENCES WITH THE AID OF AN SNP ARRAY | |
| ATE515488T1 (de) | Click-chemie zur herstellung von reportermolekülen | |
| EP1750771A4 (en) | PANCREAS MICRO RNA AND METHOD OF SUPPRESSING IT | |
| WO2004066941A3 (en) | Expression profiles for colon cancer and methods of use | |
| GB2467704A (en) | Methods of monitoring conditions by sequence analysis | |
| TW200722753A (en) | Meter having multi-level user interface | |
| DE602007013223D1 (de) | Chemisch modifizierte oligonukleotidprimer zur nukleinsäureamplifikation | |
| NO20074421L (no) | Nukleinsyrekonstrukter | |
| WO2005059108A3 (en) | Gene expression profiles and methods of use | |
| WO2008040355A3 (en) | Novel methods for quantification of micrornas and small interfering rnas | |
| DE602008006254D1 (de) | Doppel-oligonukleotid-nukleinsäurenachweisverfahren | |
| WO2007047408A3 (en) | Promac signature application | |
| EP2004824A4 (en) | NUCLEOTIDE SEQUENCES ENCODING ENZYMES IN BIOSYNTHESIS OF DIHYDROARTEMISINIC ACID | |
| DK1730315T3 (da) | Polymorphismer i NOD2/Card15 gen | |
| ATE513929T1 (de) | Gene mit einfluss auf die menschliche gedächtnisleistung | |
| WO2009076651A3 (en) | Methods for identifying compounds that modulate lisch-like protein or c1orf32 protein activity and methods of use | |
| BRPI0512745A (pt) | métodos de genotipagem e de caracterizar um agente e kit | |
| DK1664102T3 (da) | Isoleret photoprotein mtclytin, samt dets anvendelse | |
| WO2008025968A3 (en) | Method of prognosis |