DK157730C - Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden - Google Patents

Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden

Info

Publication number: DK157730C
Authority: DK; Denmark
Prior art keywords: preparation; procedure; microcasple; pharmaceutical; prepared
Prior art date: 1985-05-08

Application number

DK007487A

Other languages

English (en)

Other versions

DK157730B (da

DK7487D0 (da

DK7487A (da

Inventor

Massimo Calanchi

Leonardo Gentilini

Marco Marconi

Original Assignee

Eurand Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-08

Filing date

1987-01-07

Publication date

1990-07-16

1987-01-07 Application filed by Eurand Spa filed Critical Eurand Spa

1987-01-07 Publication of DK7487D0 publication Critical patent/DK7487D0/da

1987-01-07 Publication of DK7487A publication Critical patent/DK7487A/da

1990-02-12 Publication of DK157730B publication Critical patent/DK157730B/da

1990-07-16 Application granted granted Critical

1990-07-16 Publication of DK157730C publication Critical patent/DK157730C/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5052—Proteins, e.g. albumin
- A61K9/5057—Gelatin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Manufacturing Of Micro-Capsules (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK007487A 1985-05-08 1987-01-07 Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden DK157730C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
IT2061785		1985-05-08
IT20617/85A IT1183574B (it)	1985-05-08	1985-05-08	Metodo per ottenere una sospensione estemporanea omogenea di microcapsule
EP8600280		1986-05-02
PCT/EP1986/000280 WO1986006626A1 (en)	1985-05-08	1986-05-02	Method of preparing an extemporaneous homogeneous microcapsule suspension

Publications (4)

Publication Number	Publication Date
DK7487D0 DK7487D0 (da)	1987-01-07
DK7487A DK7487A (da)	1987-01-07
DK157730B DK157730B (da)	1990-02-12
DK157730C true DK157730C (da)	1990-07-16

Family

ID=11169617

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK007487A DK157730C (da)	1985-05-08	1987-01-07	Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden

Country Status (19)

Country	Link
US (1)	US5008117A (da)
EP (1)	EP0222856B1 (da)
JP (1)	JP2609597B2 (da)
KR (1)	KR900000212B1 (da)
AT (1)	ATE59287T1 (da)
AU (1)	AU589644B2 (da)
CA (1)	CA1274144A (da)
DE (1)	DE3676642D1 (da)
DK (1)	DK157730C (da)
ES (1)	ES8707103A1 (da)
FI (1)	FI86596C (da)
HU (1)	HUT44168A (da)
IT (1)	IT1183574B (da)
NO (1)	NO171949C (da)
NZ (1)	NZ216062A (da)
PT (1)	PT82541B (da)
RU (1)	RU2059409C1 (da)
WO (1)	WO1986006626A1 (da)
ZA (1)	ZA863399B (da)

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GB8628359D0 (en) *	1986-11-27	1986-12-31	Zyma Sa	Galenical formulation
GB8702411D0 (en) *	1987-02-03	1987-03-11	Zyma Sa	Swellable pellets
WO1989010117A1 (en) *	1988-04-19	1989-11-02	Southwest Research Institute	Controlled release of active ingredients from capsules having a salt sensitive shell material
US5064650A (en) *	1988-04-19	1991-11-12	Southwest Research Institute	Controlled-release salt sensitive capsule for oral use and adhesive system
FR2634376B1 (fr)	1988-07-21	1992-04-17	Farmalyoc	Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
NZ234143A (en) *	1989-06-28	1991-10-25	Mcneil Ppc Inc	Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US5112604A (en) *	1989-09-01	1992-05-12	Riker Laboratories, Inc.	Oral suspension formulation
IT1246350B (it) *	1990-07-11	1994-11-17	Eurand Int	Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
US5300302A (en) *	1990-10-04	1994-04-05	Nestec S.A.	Pharmaceutical composition in gel form in a dispensing package
US5252337A (en) *	1991-06-25	1993-10-12	Eurand America, Inc.	Controlled release calcium channel blocker microcapsules
US5599556A (en) *	1991-12-31	1997-02-04	Abbott Laboratories	Prolamine coatings for taste masking
US5272137A (en) *	1992-02-14	1993-12-21	Mcneil-Pfc, Inc.	Aqueous pharmaceutical suspension for pharmaceutical actives
AU3941493A (en) *	1992-03-30	1993-11-08	Alza Corporation	Viscous suspensions of controlled-release drug particles
ZA932273B (en) *	1992-03-30	1993-11-26	Alza Corp	Additives for bioerodible polymers to regulate degradation
NZ252433A (en) *	1992-04-30	1996-07-26	Schering Corp	Preparation of a dry hydrated cephalosporin powder formulation which is resistant to air oxidation and dehydration by mixing the drug with dry excipients and filling into a sealable storage container
US5422122A (en) *	1992-08-04	1995-06-06	Eurand America, Incorporated	Controlled release potassium chloride tablet
US5981719A (en)	1993-03-09	1999-11-09	Epic Therapeutics, Inc.	Macromolecular microparticles and methods of production and use
US6090925A (en)	1993-03-09	2000-07-18	Epic Therapeutics, Inc.	Macromolecular microparticles and methods of production and use
CA2121435C (en) *	1993-04-16	2002-01-22	Sheila M. Ratnaraj	Aqueous pharmaceutical suspension and process for preparation thereof
GB2318511A (en) *	1996-10-23	1998-04-29	Eurand Int	Process for the preparation of a pharmaceutical composition for rapid suspension in water
RU2147923C1 (ru) *	1997-12-02	2000-04-27	Ивановский государственный университет	Способ получения микрокапсул
UA65607C2 (uk) *	1998-03-04	2004-04-15	Орто-Макнейл Фармацевтикал, Інк.	Фармацевтична композиція (варіанти) та спосіб її приготування
GB9822170D0 (en) *	1998-10-13	1998-12-02	Danbioyst Uk Ltd	Novel formulations of fexofenadine
US6723342B1 (en)	1999-02-08	2004-04-20	Fmc Corporation	Edible coating composition
US6432448B1 (en)	1999-02-08	2002-08-13	Fmc Corporation	Edible coating composition
US6159491A (en) *	1999-02-12	2000-12-12	Biovector Technologies, Inc.	Prolonged release bioadhesive vaginal gel dosage form
US6500462B1 (en)	1999-10-29	2002-12-31	Fmc Corporation	Edible MCC/PGA coating composition
US6932861B2 (en)	2000-11-28	2005-08-23	Fmc Corporation	Edible PGA coating composition
JP2004531467A (ja)	2000-11-28	2004-10-14	エフ　エム　シー　コーポレーション	可食性ｐｇａ被覆組成物
AU2002221096A1 (en) *	2000-12-11	2002-06-24	Takeda Chemical Industries Ltd.	Medicinal compositions improved in solublity in water
JP2004168703A (ja) *	2002-11-20	2004-06-17	Shin Etsu Chem Co Ltd	マイクロカプセル及びその製造方法
US20040170686A1 (en) *	2003-01-31	2004-09-02	Fredrickson Jennifer K.	Suspension vehicle for coated drug particles
US20040191326A1 (en) *	2003-03-31	2004-09-30	Reo Joseph P.	Taste-masking vehicle for coated oxazolidinone particles
US7632521B2 (en) *	2003-07-15	2009-12-15	Eurand, Inc.	Controlled release potassium chloride tablets
US20050118194A1 (en) *	2003-12-01	2005-06-02	Sin Yoke M.	Oral vaccine, method for its preparation and use thereof
US20060134210A1 (en) *	2004-12-22	2006-06-22	Astrazeneca Ab	Solid dosage form comprising proton pump inhibitor and suspension made thereof
WO2018130876A1 (en) *	2017-01-10	2018-07-19	Dukebox Sp. Z O. O.	A method of manufacturing a suspension of nanoparticles of potassium salt or magnesium salt
ES2964108T3 (es)	2019-02-22	2024-04-04	Catalent Uk Swindon Zydis Ltd	Minimización de la aglomeración de material de recubrimiento de partículas farmacológicas durante el almacenamiento para estabilizar los tiempos de disgregación de los productos farmacéuticos
WO2020169988A1 (en) *	2019-02-22	2020-08-27	Catalent U.K. Swindon Zydis Limited	Minimizing aeration of suspensions during in-line mixing
CN113438942A (zh)	2019-02-22	2021-09-24	康特伦英国斯温顿捷迪斯有限公司	在水性混悬液中保持通过无溶剂混合方法生产的功能性包衣api颗粒
TW202045153A (zh)	2019-02-22	2020-12-16	英商康泰倫特英國斯文敦載迪斯有限公司	含伊布洛芬之醫藥組合物之塗層之黏聚最小化、通氣及保存
RU2731599C1 (ru) *	2019-07-17	2020-09-04	Общество с ограниченной ответственностью "РУСИНТЕХ"	Способ получения микрокапсулированного термоактивируемого огнегасящего агента
CN115968281A (zh)	2020-07-31	2023-04-14	康特伦英国斯温顿捷迪斯有限公司	包含经包衣api的药物组合物

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GB844772A (en) *	1956-04-19	1960-08-17	Pfizer & Co C	Granular pharmaceutical compositions and process for preparing same
FR2077696B1 (da) *	1970-02-06	1973-03-16	Synthelabo
DE2211019C3 (de) *	1972-03-08	1980-08-28	Bayer Ag, 5090 Leverkusen	Geschmacksverbessernde Formulierungen oraler Penicilline
US4155741A (en) *	1974-05-01	1979-05-22	Stauffer Chemical Company	Stable suspension system for microencapsulated flowable formulations, and method of preparing stable suspension of microcapsules
US4126672A (en) *	1976-02-04	1978-11-21	Hoffmann-La Roche Inc.	Sustained release pharmaceutical capsules
US4189499A (en) *	1977-03-16	1980-02-19	Biochefarm S.A.	Lysine 4-allyloxy-3-chlorophenylacetate and method of its preparation
IT1148784B (it) *	1980-04-09	1986-12-03	Eurand Spa	Procedimento per la preparazione di microcapsule in un veicolo liquido
IT1209276B (it) *	1980-11-05	1989-07-16	Magis Farmaceutici	Composizione farmaceutica per la somministrazione orale del metilestere dell'acido 13a-etil-2,3,5,6,12,13,13a,13b-ottaidro-12-idrossi1h-indolo-[3,2,1-de] pirido [3,2,1-ij] [1,5] naftiridina -12-carbossilico

1985
- 1985-05-08 IT IT20617/85A patent/IT1183574B/it active
1986
- 1986-05-02 RU SU874028804A patent/RU2059409C1/ru active
- 1986-05-02 AU AU59031/86A patent/AU589644B2/en not_active Ceased
- 1986-05-02 JP JP61503027A patent/JP2609597B2/ja not_active Expired - Fee Related
- 1986-05-02 HU HU863345A patent/HUT44168A/hu unknown
- 1986-05-02 KR KR1019860700872A patent/KR900000212B1/ko not_active Expired
- 1986-05-02 DE DE8686903323T patent/DE3676642D1/de not_active Expired - Lifetime
- 1986-05-02 EP EP86903323A patent/EP0222856B1/en not_active Expired - Lifetime
- 1986-05-02 AT AT86903323T patent/ATE59287T1/de not_active IP Right Cessation
- 1986-05-02 WO PCT/EP1986/000280 patent/WO1986006626A1/en not_active Ceased
- 1986-05-05 NZ NZ216062A patent/NZ216062A/xx unknown
- 1986-05-07 CA CA000508635A patent/CA1274144A/en not_active Expired - Lifetime
- 1986-05-07 ZA ZA863399A patent/ZA863399B/xx unknown
- 1986-05-08 PT PT82541A patent/PT82541B/pt not_active IP Right Cessation
- 1986-05-08 ES ES554777A patent/ES8707103A1/es not_active Expired
- 1986-12-18 NO NO865162A patent/NO171949C/no not_active IP Right Cessation
- 1986-12-30 FI FI865336A patent/FI86596C/fi not_active IP Right Cessation
1987
- 1987-01-07 DK DK007487A patent/DK157730C/da not_active IP Right Cessation
1988
- 1988-12-20 US US07/287,401 patent/US5008117A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES8707103A1 (es)	1987-07-16
RU2059409C1 (ru)	1996-05-10
ATE59287T1 (de)	1991-01-15
DK157730B (da)	1990-02-12
KR870700209A (ko)	1987-05-30
IT1183574B (it)	1987-10-22
NO171949B (no)	1993-02-15
DE3676642D1 (de)	1991-02-07
ZA863399B (en)	1987-01-28
US5008117A (en)	1991-04-16
DK7487D0 (da)	1987-01-07
DK7487A (da)	1987-01-07
EP0222856A1 (en)	1987-05-27
EP0222856B1 (en)	1990-12-27
NO865162L (no)	1986-12-18
PT82541A (en)	1986-06-01
IT8520617A0 (it)	1985-05-08
AU589644B2 (en)	1989-10-19
NZ216062A (en)	1989-07-27
ES554777A0 (es)	1987-07-16
NO171949C (no)	1993-05-26
KR900000212B1 (ko)	1990-01-23
FI86596C (fi)	1992-09-25
PT82541B (pt)	1988-03-03
FI86596B (fi)	1992-06-15
JPS62502859A (ja)	1987-11-12
JP2609597B2 (ja)	1997-05-14
HUT44168A (en)	1988-02-29
FI865336A0 (fi)	1986-12-30
CA1274144A (en)	1990-09-18
AU5903186A (en)	1986-12-04
WO1986006626A1 (en)	1986-11-20
FI865336L (fi)	1986-12-30

Publication	Publication Date	Title
DK157730C (da)	1990-07-16	Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden
DK158718C (da)	1990-12-03	Fremgangsmaade til flokkulation af suspenderede faste stoffer i en vandig suspension
ES2060107T3 (es)	1994-11-16	Nuevo procedimiento de preparacion de microparticulas lipidicas.
ATE47715T1 (de)	1989-11-15	Stabile salze von sam mit polyanionen.
NZ504017A (en)	2001-09-28	Preparation of gatifloxacin and disodium edetate
DK280789A (da)	1989-12-12	Komplekser af beta-cyclodextrin med salte af ibuprofen, fremgangsmaade til fremstilling af saadanne komplekser og farmaceutiske midler indeholdende disse
IT8767610A0 (it)	1987-07-14	Particelle polimeriche prodotte per via sequenziale dispersioni acquose che le comprendono loro preparazione e impiego
BR9609614A (pt)	1999-05-25	Composição e processos para prover pelo menos uma dentre a coagulação e a despegajosidade de partículas sólidas em suspensão em um sistema aquoso para desemulsificar um emulsão oleo-em-água
NO881625L (no)	1988-10-17	Fremgangsmaate for fremstilling av stabile sucralfatsuspensjoner.
DE69014040D1 (de)	1994-12-15	Verfahren zur Herstellung von Alkylglykoside oder wässriger Lösung davon.
DE68921371D1 (de)	1995-04-06	Verfahren zur Herstellung einer an Faktor-VIIa angereicherten Fraktion und ihre Verwendung als Arzneimittel.
FI854178A7 (fi)	1986-04-28	1,2,4-triatsolo-karbamaatti ja sen happoadditiosuolat, näiden valmistusmenetelmät ja lääkeaineet.
EA200200294A1 (ru)	2002-08-29	Сферические агломераты телитромицина, способ их получения и их применение для приготовления лекарственных форм
BR9904286A (pt)	2000-09-26	Suspensões antiácidas e antigás termoestáveis
DK565486D0 (da)	1986-11-25	Carboxylgruppeholdige polyamider, fremgangsmaader til fremstilling heraf samt deres anvendelse til fremstilling af vandige bronzedispersioner
DK319384A (da)	1985-01-03	1-0-alkyl-3-amino-propan-1,2-diol-2-0-phospholipider, fremgangsmaade til deres fremstilling samt farmaceutiske praeparater indeholdende disse
ES2018562B3 (es)	1991-04-16	Copolimero acrilato acrilamida de bajo peso molecular y procedimiento para impedir, al menos en parte, la formacion de depositos de sales disueltas en medios acuosos
Swislocki et al.	1989	Effects of pentoxifylline on Ca2+‐dependent transglutaminase in rat erythrocytes
GR890100737A (el)	1990-12-31	Μέ?οδος παρασκευής μιας φαρμακευτικής συν?έσεως δι'οφ?αλμική χρήσιν η οποία περιλαμβάνει ένα υδατοδιαλυτό άλας δια προσ?ήκης οξέος ιμποπαμίνης.
IT8620295A0 (it)	1986-05-02	Sospensione acquosa di carbone e relativi procedimenti di preparazione.
NO863735L (no)	1987-03-30	Fremgangsmaate for fremstilling av ranitidin eller syreaddisjonssalter derav.
DK86488A (da)	1988-08-25	Monobasisk phosphatsalt af dobutamin, fremgangsmaade til fremstilling af et saadant salt samt farmaceutisk praeparat indeholdende saltet
FI880370A7 (fi)	1988-08-17	Niukkaliukoisten hiukkasmaisten aineiden vesidispersio.
FI904973A7 (fi)	1991-06-05	Menetelmä ja seos vesipitoisen kiintoaineen sulattamiseksi
DK42986A (da)	1986-07-30	Fremgangsmaade til fremstilling af 3,5-diamino-1,2,4-triazolderivater eller syreadditionssalte deraf

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2004-02-02	PBP	Patent lapsed	Country of ref document: DK