DK157580A - Fremgangsmaade til fremstilling af 7-(2-(2-amino4-thiazolyl)-2-( (1-carboxy-1,1-dialkyl) alkoxyimino) acetamido) cephemsulfoxider - Google Patents

Fremgangsmaade til fremstilling af 7-(2-(2-amino4-thiazolyl)-2-( (1-carboxy-1,1-dialkyl) alkoxyimino) acetamido) cephemsulfoxider

Info

Publication number: DK157580A
Authority: DK; Denmark
Prior art keywords: alcoxyimino; amino4; sulphoxides; cephem; acetamido
Prior art date: 1979-04-12

Application number

DK157580A

Other languages

English (en)

Inventor

C M Cimarusti

W H Koster

R B Sykes

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-04-12

Filing date

1980-04-11

Publication date

1980-10-13

1980-04-11 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1980-10-13 Publication of DK157580A publication Critical patent/DK157580A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK157580A 1979-04-12 1980-04-11 Fremgangsmaade til fremstilling af 7-(2-(2-amino4-thiazolyl)-2-( (1-carboxy-1,1-dialkyl) alkoxyimino) acetamido) cephemsulfoxider DK157580A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/029,417 US4237128A (en)	1979-04-12	1979-04-12	7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides

Publications (1)

Publication Number	Publication Date
DK157580A true DK157580A (da)	1980-10-13

Family

ID=21848908

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK157580A DK157580A (da)	1979-04-12	1980-04-11	Fremgangsmaade til fremstilling af 7-(2-(2-amino4-thiazolyl)-2-( (1-carboxy-1,1-dialkyl) alkoxyimino) acetamido) cephemsulfoxider

Country Status (20)

Country	Link
US (1)	US4237128A (da)
JP (1)	JPS55141489A (da)
AU (1)	AU538177B2 (da)
BE (1)	BE882758A (da)
CA (1)	CA1147323A (da)
CH (1)	CH653035A5 (da)
DE (1)	DE3013966A1 (da)
DK (1)	DK157580A (da)
FR (1)	FR2465737A1 (da)
GB (1)	GB2049675B (da)
HU (1)	HU182686B (da)
IE (1)	IE49657B1 (da)
IT (1)	IT1149833B (da)
LU (1)	LU82352A1 (da)
NL (1)	NL8002126A (da)
NO (1)	NO801052L (da)
NZ (1)	NZ193317A (da)
PH (4)	PH15386A (da)
SE (1)	SE8002769L (da)
ZA (1)	ZA801787B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE878514A (fr) *	1978-09-04	1980-02-29	Fujisawa Pharmaceutical Co	Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
DE2716677C2 (de) *	1977-04-15	1985-10-10	Hoechst Ag, 6230 Frankfurt	Cephemderivate und Verfahren zu ihrer Herstellung
AR228726A1 (es) *	1978-05-26	1983-04-15	Glaxo Group Ltd	Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
AR229882A1 (es) *	1978-05-26	1983-12-30	Glaxo Group Ltd	Procedimiento para preparar antibioticos de cefalosporina
BE880068A (fr) *	1978-11-17	1980-05-16	Glaxo Group Ltd	Nouvelles cephalosporines et leur preparation
US4275062A (en) *	1979-09-19	1981-06-23	E. R. Squibb & Sons, Inc.	Aminothiazolyl ureido sulfoxide cephalosporins
GR75706B (da) *	1980-06-30	1984-08-02	Sanofi Sa
FR2501209B1 (fr) *	1981-03-03	1986-07-04	Sanofi Sa	Nouveaux derives des cephalosporines et medicaments antibiotiques contenant lesdits derives
DE3045805A1 (de)	1980-12-05	1982-07-08	Basf Ag, 6700 Ludwigshafen	Diphenylether, verfahren zu ihrer herstellung und ihre verwendung als herbizide
US4336253A (en) *	1981-03-11	1982-06-22	Eli Lilly And Company	Cephalosporin antibiotics
JPS5859991A (ja) *	1981-09-14	1983-04-09	Fujisawa Pharmaceut Co Ltd	新規セフェム化合物
FR2516515A1 (fr) *	1981-11-16	1983-05-20	Sanofi Sa	Nouveaux derives de pyridinium thiomethyl cephalosporines, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2517309A1 (fr) *	1981-12-01	1983-06-03	Sanofi Sa	Nouveaux derives de cephalosporines substitues en position 3 par un groupe heterocycle thiomethyl; procede de preparation desdits composes et compositions pharmaceutiques en contenant
US4474954A (en) *	1981-12-07	1984-10-02	Bristol-Myers Company	Intermediates for cephalosporin derivatives
US4394503A (en) *	1981-12-07	1983-07-19	Bristol-Myers Company	Cephalosporin derivatives
US4704457A (en) *	1982-06-21	1987-11-03	E. R. Squibb & Sons, Inc.	Process for the preparation of (3S)-3-[[[2-(protected amino)-4-thiazolyl]-oxoacetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof
US4783443A (en) *	1986-03-03	1988-11-08	The University Of Chicago	Amino acyl cephalosporin derivatives
CA2536910A1 (en) *	2003-08-25	2005-03-10	Revaax Pharmaceuticals, Llc	Oral neurotherapeutic cefazolin compositions

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3641014A (en) *	1968-10-03	1972-02-08	Lilly Co Eli	Reduction of delta**3-cephalosporin sulfoxides
US4138555A (en) *	1971-05-14	1979-02-06	Glaxo Laboratories, Limited	(6R,7R)-7-[2-aryl-2-(etherified oximino)acetamido]-3-carbamoyloxymethylceph-3-em-4-carboxylic acid 1-oxides
US4091209A (en) *	1971-05-14	1978-05-23	Glaxo Laboratories Limited	7β-[2-Etherified oximino-2-(phenyl or naphthylacetamido)]cephalosporins having a 2-haloalkylcarbamoyloxymethyl group at the 3-position
US3971778A (en) *	1972-05-12	1976-07-27	Glaxo Laboratories Limited	Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position
US4075337A (en) *	1972-07-18	1978-02-21	Gist-Brocades N.V.	Methods of combatting bacterial infections in warm-blooded animal with cephalsporin R-sulfoxide
US4084049A (en) *	1972-10-20	1978-04-11	Fujisawa Pharmaceutical Co., Ltd.	Cepham derivatives
US4144393A (en) *	1973-12-21	1979-03-13	Glaxo Laboratories Limited	3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group
DK154939C (da) *	1974-12-19	1989-06-12	Takeda Chemical Industries Ltd	Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
SE439312B (sv)	1977-03-25	1985-06-10	Roussel Uclaf	Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
DE2716677C2 (de)	1977-04-15	1985-10-10	Hoechst Ag, 6230 Frankfurt	Cephemderivate und Verfahren zu ihrer Herstellung
AT365597B (de) *	1978-05-26	1982-01-25	Glaxo Group Ltd	Verfahren zur herstellung von neuen cephalosporin-antibiotika
AR229882A1 (es) *	1978-05-26	1983-12-30	Glaxo Group Ltd	Procedimiento para preparar antibioticos de cefalosporina
AR228726A1 (es) *	1978-05-26	1983-04-15	Glaxo Group Ltd	Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
SE438859B (sv) *	1978-05-26	1985-05-13	Glaxo Group Ltd	7-acylamido-3-karbamoyloximetyl-3-cefem-4-karboxylsyraderivat och forfarande for framstellning derav

1979
- 1979-04-12 US US06/029,417 patent/US4237128A/en not_active Expired - Lifetime
1980
- 1980-03-25 CA CA000348408A patent/CA1147323A/en not_active Expired
- 1980-03-26 ZA ZA00801787A patent/ZA801787B/xx unknown
- 1980-03-28 PH PH23827A patent/PH15386A/en unknown
- 1980-03-28 AU AU56953/80A patent/AU538177B2/en not_active Ceased
- 1980-03-31 NZ NZ193317A patent/NZ193317A/en unknown
- 1980-04-02 IE IE669/80A patent/IE49657B1/en unknown
- 1980-04-08 FR FR8007857A patent/FR2465737A1/fr active Granted
- 1980-04-09 LU LU82352A patent/LU82352A1/fr unknown
- 1980-04-11 DK DK157580A patent/DK157580A/da not_active IP Right Cessation
- 1980-04-11 IT IT21343/80A patent/IT1149833B/it active
- 1980-04-11 NO NO801052A patent/NO801052L/no unknown
- 1980-04-11 SE SE8002769A patent/SE8002769L/xx not_active Application Discontinuation
- 1980-04-11 BE BE0/200202A patent/BE882758A/fr not_active IP Right Cessation
- 1980-04-11 CH CH2824/80A patent/CH653035A5/de not_active IP Right Cessation
- 1980-04-11 DE DE19803013966 patent/DE3013966A1/de not_active Withdrawn
- 1980-04-11 NL NL8002126A patent/NL8002126A/xx not_active Application Discontinuation
- 1980-04-11 HU HU80892A patent/HU182686B/hu unknown
- 1980-04-12 JP JP4854780A patent/JPS55141489A/ja active Pending
- 1980-04-14 GB GB8012257A patent/GB2049675B/en not_active Expired
1981
- 1981-10-12 PH PH26339A patent/PH19111A/en unknown
1982
- 1982-01-25 PH PH26789A patent/PH17514A/en unknown
1983
- 1983-09-08 PH PH29511A patent/PH18939A/en unknown

Also Published As

Publication number	Publication date
FR2465737A1 (fr)	1981-03-27
NZ193317A (en)	1984-04-27
NL8002126A (nl)	1980-10-14
IT8021343A0 (it)	1980-04-11
SE8002769L (sv)	1980-12-12
PH15386A (en)	1982-12-23
PH19111A (en)	1986-01-06
LU82352A1 (fr)	1980-12-16
NO801052L (no)	1980-10-13
CA1147323A (en)	1983-05-31
DE3013966A1 (de)	1980-11-20
BE882758A (fr)	1980-10-13
ZA801787B (en)	1981-03-25
HU182686B (en)	1984-02-28
FR2465737B1 (da)	1984-04-27
JPS55141489A (en)	1980-11-05
CH653035A5 (de)	1985-12-13
IT1149833B (it)	1986-12-10
AU538177B2 (en)	1984-08-02
IE800669L (en)	1980-10-12
PH17514A (en)	1984-09-07
AU5695380A (en)	1980-10-16
GB2049675A (en)	1980-12-31
PH18939A (en)	1985-11-14
GB2049675B (en)	1983-05-18
US4237128A (en)	1980-12-02
IE49657B1 (en)	1985-11-13

Publication	Publication Date	Title
DK157580A (da)	1980-10-13	Fremgangsmaade til fremstilling af 7-(2-(2-amino4-thiazolyl)-2-( (1-carboxy-1,1-dialkyl) alkoxyimino) acetamido) cephemsulfoxider
DK554279A (da)	1980-06-30	Fremgangsmaade til fremstilling af cepham- og cephemderivater
DK155525C (da)	1989-09-04	Fremgangsmaade til fremstilling af (6r,7r)-7-oe(z)-2-(2-aminotiazol-4-yl)-2-(2-karboxyprop-2-oxyimino)-acetamidoaa-3-(1-pyridiniummetyl)-ceph-3-em-4-karboxylat-pentahydrat
ES500792A0 (es)	1982-06-01	Procedimiento para preparar derivados de cefalosporina
FI830704A7 (fi)	1983-09-05	Kefalosporiinijohdannaiset ja menetelmä niiden valmistamiseksi.
DK151024C (da)	1988-02-29	Fremgangsmaade til fremstilling af 6-(d-alfa-amino-(p-hydroxyphenyl)acetamido)-penicillansyre
FI801642A7 (fi)	1981-01-01	Menetelmä uusien vinyyli-3 kefalosporiinien valmistamiseksi.
DK154180A (da)	1980-10-12	Fremgangsmaade til fremstilling af penem-3-carboxylsyrederivatier
DK158669C (da)	1991-01-21	Fremgangsmaade til fremstilling af 6beta-halogensubstituerede penicillansyrederivater.
FI811879A7 (fi)	1981-12-19	Uusia kefemyhdisteitä ja niiden valmistusmenetelmiä.
DK99980A (da)	1980-09-09	Fremgangsmaade til fremstilling af mercaptoacyldihydropyrazolcarboxylsyrederivater
DK554481A (da)	1982-06-16	Fremgangsmaade til fremstilling af cephalosporansyrederivater
FI831253A7 (fi)	1983-10-20	Menetelmä uusien oksatsolijohdosten valmistamiseksi.
NL7901242A (nl)	1979-08-21	Nieuwe gesubstitueerde 2-fenylimino-imidazolidinen, de zuuradditiezouten daarvan, de deze verbindingen bevat- tende preparaten en werkwijzen ter bereiding daarvan.
ES508280A0 (es)	1983-02-16	Procedimiento para preparar derivados de cefalosporina.
DK457983D0 (da)	1983-10-04	Fremgangsmade til fremstilling af beta-lactam
ES513256A0 (es)	1983-07-01	Procedimiento para preparar derivados de cefalosporina.
FI800602A7 (fi)	1981-01-01	Menetelmä penisilliinijohdannaisten valmistamiseksi.
FI812778A7 (fi)	1982-03-18	Menetelmä kefalosporiini-yhdisteiden valmistamiseksi.
FI841766A7 (fi)	1984-11-08	Menetelmä kefeemiyhdisteiden valmistamiseksi.
FI792322A7 (fi)	1981-01-01	Kefeemiyhdisteiden valmistusmenetelmä.
DK20782A (da)	1982-07-20	Fremgangsmaade til fremstilling af cephalosporansyrederivater
FI803015A7 (fi)	1981-01-01	Menetelmä penisilliinien valmistamiseksi.
DK358381A (da)	1982-02-14	Fremgangsmaade til fremstilling af 3-amino-1,2-propandiolderivater
FI802501A7 (fi)	1981-01-01	Menetelmä klavulaanihappojohdannaisien valmistmiseksi.

Legal Events

Date	Code	Title	Description
1986-05-12	ATS	Application withdrawn
1993-02-22	PBP	Patent lapsed