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DK1541674T3 - Primære dyrkede adipocyter til genterapi - Google Patents

Primære dyrkede adipocyter til genterapi

Info

Publication number
DK1541674T3
DK1541674T3 DK03736235.7T DK03736235T DK1541674T3 DK 1541674 T3 DK1541674 T3 DK 1541674T3 DK 03736235 T DK03736235 T DK 03736235T DK 1541674 T3 DK1541674 T3 DK 1541674T3
Authority
DK
Denmark
Prior art keywords
gene therapy
primary cultured
adipocytes
cells
present
Prior art date
Application number
DK03736235.7T
Other languages
English (en)
Inventor
Masashi Ito
Yasushi Saito
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Application granted granted Critical
Publication of DK1541674T3 publication Critical patent/DK1541674T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK03736235.7T 2002-06-18 2003-06-18 Primære dyrkede adipocyter til genterapi DK1541674T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002177648 2002-06-18
JP2002237974 2002-08-19
PCT/JP2003/007721 WO2003106663A1 (ja) 2002-06-18 2003-06-18 遺伝子治療用初代培養脂肪細胞

Publications (1)

Publication Number Publication Date
DK1541674T3 true DK1541674T3 (da) 2011-03-14

Family

ID=29738440

Family Applications (2)

Application Number Title Priority Date Filing Date
DK10161291.9T DK2213730T3 (da) 2002-06-18 2003-06-18 Primære dyrkede adipocytter til genterapi
DK03736235.7T DK1541674T3 (da) 2002-06-18 2003-06-18 Primære dyrkede adipocyter til genterapi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK10161291.9T DK2213730T3 (da) 2002-06-18 2003-06-18 Primære dyrkede adipocytter til genterapi

Country Status (20)

Country Link
US (2) US7820438B2 (da)
EP (2) EP1541674B9 (da)
JP (1) JPWO2003106663A1 (da)
KR (1) KR101004086B1 (da)
CN (1) CN1671836B (da)
AT (1) ATE492630T1 (da)
AU (1) AU2003242459B2 (da)
BR (1) BRPI0312441B8 (da)
CA (1) CA2488414C (da)
DE (1) DE60335473D1 (da)
DK (2) DK2213730T3 (da)
ES (1) ES2559430T3 (da)
HU (1) HUE025872T2 (da)
MA (1) MA27324A1 (da)
MX (1) MXPA04012859A (da)
NZ (1) NZ537072A (da)
PT (2) PT1541674E (da)
SI (1) SI1541674T1 (da)
WO (1) WO2003106663A1 (da)
ZA (1) ZA200500464B (da)

Families Citing this family (15)

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Publication number Priority date Publication date Assignee Title
JP4879867B2 (ja) * 2002-06-18 2012-02-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 遺伝子治療用初代培養脂肪細胞
EP1892294A4 (en) * 2005-06-15 2010-04-14 Takara Bio Inc METHOD OF TRANSFERRING GENES IN FAT CELLS OR PRECURSOR FAT CELLS
WO2008108344A1 (ja) * 2007-03-02 2008-09-12 Cellgentech, Inc. Ｌｃａｔ欠損症の遺伝子治療用細胞並びにこれを産生するのに用いられる複製欠損性レトロウイルスベクター及びプラスミド
TW200927074A (en) * 2007-12-25 2009-07-01 Univ Nat Taiwan Colloidal frame used in tissue engineering
JP2009165403A (ja) * 2008-01-16 2009-07-30 Hokkaido Univ ハニカム状多孔質体を用いた脂肪細胞の長期培養方法
CN102245765B (zh) * 2008-10-21 2015-01-07 通用医院公司 细胞移植
WO2011090091A1 (ja) * 2010-01-21 2011-07-28 セルジェンテック株式会社 遺伝子治療用脂肪細胞の調製のための外来遺伝子の導入に適した細胞集団かどうかを判定する方法
EP3530741B1 (en) 2010-08-06 2021-04-07 The General Hospital Corporation D/B/A Massachusetts General Hospital System and apparatus for cell treatment
KR20200021108A (ko) * 2011-03-16 2020-02-27 주식회사 쿠라레 배양 방법, 성숙 지방 세포군 및 약물 스크리닝 방법
JP2023002772A (ja) * 2011-09-23 2023-01-10 レジニアス リミテッド 脂肪細胞および細胞分泌物を使用する治療
KR102560970B1 (ko) 2016-03-31 2023-07-31 엘지전자 주식회사 청소기
WO2021241659A1 (ja) 2020-05-29 2021-12-02 株式会社 Numt Ｆｆａｒ４を高発現させた脂肪細胞及びその使用
EP4213863A4 (en) * 2020-09-15 2025-02-26 The Brigham and Women's Hospital, Inc. In vivo adipose bioreactor and kits for the production and delivery of biologic agents
WO2023249904A1 (en) * 2022-06-20 2023-12-28 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for treating diabetes
CN117138053B (zh) * 2023-08-10 2025-02-14 吉林化工学院 一种脂肪细胞载体药物及其应用

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US4956455A (en) 1984-03-05 1990-09-11 The Salk Institute For Biological Studies Bovine fibroblast growth factor
US4829000A (en) * 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
DE3689845T3 (de) 1985-09-12 2001-11-15 Scios Inc., Sunnyvale Rekombinanter fibroblast-wachstumsfaktor.
EP0226181B1 (en) 1985-12-17 1994-06-15 Synergen, Inc. Human placenta angiogenic factor capable of stimulating capillary endothelial cell protease synthesis, DNA synthesis and migration
IL81839A0 (en) 1986-03-14 1987-10-20 Takeda Chemical Industries Ltd Polypeptide,dna and its use
JP2526965B2 (ja) 1987-02-24 1996-08-21 武田薬品工業株式会社 ムテイン，ｄｎａおよびその用途
FI893530A0 (fi) 1987-11-24 1989-07-21 Amgen Inc Analoger av fibroblast -tillvaextfaktorn.
EP0326907A1 (en) 1988-01-26 1989-08-09 Takeda Chemical Industries, Ltd. Polypeptide, DNA and its use
CA2015313A1 (en) 1989-04-26 1990-10-26 Masaharu Senoo Glycosylated fgf and production thereof
JP3135138B2 (ja) 1990-12-19 2001-02-13 科研製薬株式会社 骨疾患治療剤
AU7568094A (en) * 1993-08-12 1995-03-14 Cytotherapeutics, Inc. Improved compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
FR2731014B1 (fr) 1995-02-23 1997-03-28 Rhone Poulenc Rorer Sa Molecules d'adn, preparation et utilisation en therapie genique
FR2731710B1 (fr) 1995-03-14 1997-04-30 Rhone Poulenc Rorer Sa Virus recombinants exprimant la lecithine cholesterol acyltransferase et utilisations en therapie genique
US5869037A (en) 1996-06-26 1999-02-09 Cornell Research Foundation, Inc. Adenoviral-mediated gene transfer to adipocytes
GB2327224A (en) 1997-07-09 1999-01-20 Mayo Foundation Gene transfer to adipocytes
WO1999011786A1 (fr) 1997-09-01 1999-03-11 Otsuka Pharmaceutical Co., Ltd. GENE pancpin ET COMPOSITION DE THERAPIE GENIQUE
CA2308575A1 (en) 1997-11-03 1999-05-14 Tom Tsang Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
US6797505B2 (en) 1998-05-27 2004-09-28 Cell Genesys, Inc. Recombinant AAV vectors for gene therapy of hemophilia A
WO2000031267A1 (en) * 1998-11-20 2000-06-02 The Autonomous University Of Barcelona Insulin production by engineered muscle cells
US6153432A (en) 1999-01-29 2000-11-28 Zen-Bio, Inc Methods for the differentiation of human preadipocytes into adipocytes
HK1049350B (en) * 1999-08-05 2012-01-27 Abt Holding Company Multipotent adult stem cells and methods for isolation
US7015037B1 (en) * 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US20020177551A1 (en) 2000-05-31 2002-11-28 Terman David S. Compositions and methods for treatment of neoplastic disease
CN100595274C (zh) * 2000-07-18 2010-03-24 雀巢制品公司 前脂肪细胞系
AU2002332028A1 (en) * 2001-10-06 2003-04-22 Boston Medical Center Corporation Preadipocyte cell strains and uses therefore
EP1496978A4 (en) 2002-04-03 2006-11-29 Artecel Sciences Inc IMPROVEMENTS IN DIFFERENTIATED ADULT DIFFERENTIATED STEM CELLS DERIVED FROM ADIPOSE TISSUE AND USES THEREOF
WO2008108344A1 (ja) 2007-03-02 2008-09-12 Cellgentech, Inc. Ｌｃａｔ欠損症の遺伝子治療用細胞並びにこれを産生するのに用いられる複製欠損性レトロウイルスベクター及びプラスミド

Also Published As

Publication number Publication date
BRPI0312441B8 (pt) 2021-05-25
EP1541674A1 (en) 2005-06-15
BRPI0312441B1 (pt) 2018-03-20
CA2488414C (en) 2011-04-26
KR101004086B1 (ko) 2010-12-27
ATE492630T1 (de) 2011-01-15
BR0312441A (pt) 2005-04-19
PT1541674E (pt) 2011-03-21
ES2559430T3 (es) 2016-02-12
EP2213730B1 (en) 2015-12-02
NZ537072A (en) 2006-12-22
JPWO2003106663A1 (ja) 2005-10-13
MA27324A1 (fr) 2005-05-02
US20090010901A1 (en) 2009-01-08
US8071085B2 (en) 2011-12-06
AU2003242459B2 (en) 2007-05-17
ZA200500464B (en) 2005-12-28
CN1671836B (zh) 2012-02-08
HUE025872T2 (en) 2016-05-30
EP2213730A1 (en) 2010-08-04
PT2213730E (pt) 2016-02-26
SI1541674T1 (sl) 2011-04-29
EP1541674A4 (en) 2007-01-10
AU2003242459A1 (en) 2003-12-31
EP2213730A8 (en) 2010-11-10
DE60335473D1 (de) 2011-02-03
EP1541674B9 (en) 2011-09-14
US20060121008A1 (en) 2006-06-08
CA2488414A1 (en) 2003-12-24
US7820438B2 (en) 2010-10-26
KR20070087062A (ko) 2007-08-27
CN1671836A (zh) 2005-09-21
EP1541674B1 (en) 2010-12-22
DK2213730T3 (da) 2016-01-25
WO2003106663A1 (ja) 2003-12-24
MXPA04012859A (es) 2005-03-31

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