DK149790D0 - 0-(3amino-2-hydroxypropyl)-hydroximsyrehalogenider og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende en eller flere af halogeniderne og disses anvendelse - Google Patents

0-(3amino-2-hydroxypropyl)-hydroximsyrehalogenider og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende en eller flere af halogeniderne og disses anvendelse

Info

Publication number: DK149790D0
Authority: DK; Denmark
Prior art keywords: halogenides; hydroxypropyl; procedures; amino; preparing
Prior art date: 1988-10-20

Application number

DK149790A

Other languages

English (en)

Other versions

DK149790A (da

DK175584B1 (da

Inventor

Nagy Peter Literati

Bela Balazs

Maria Boross

Jenoe Szilbereky

Gizella Zsila

Lajos Abraham

Gyoergy Blasko

Bela Gachalyi

Attila Almasi

Gabor Nemeth

Original Assignee

Biorex Kutato Fejlesztoe Kft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-20

Filing date

1990-06-19

Publication date

1990-06-19

1990-06-19 Application filed by Biorex Kutato Fejlesztoe Kft filed Critical Biorex Kutato Fejlesztoe Kft

1990-06-19 Publication of DK149790A publication Critical patent/DK149790A/da

1990-06-19 Publication of DK149790D0 publication Critical patent/DK149790D0/da

2004-12-13 Application granted granted Critical

2004-12-13 Publication of DK175584B1 publication Critical patent/DK175584B1/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/08—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyridine Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

DK199001497A 1988-10-20 1990-06-19 0-(3-amino-2-hydroxypropyl)-hydroximsyrehalogenider og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende en eller flere af halogeniderne og disses anvendelse DK175584B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
HU885405A HU207988B (en)	1988-10-20	1988-10-20	Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components
HU540588		1988-10-20
HU8900048		1989-10-19
PCT/HU1989/000048 WO1990004584A1 (en)	1988-10-20	1989-10-19	Novel o-(3-amino-2-hydroxypropyl)-hydroximic acid halides and process for preparing the same

Publications (3)

Publication Number	Publication Date
DK149790A DK149790A (da)	1990-06-19
DK149790D0 true DK149790D0 (da)	1990-06-19
DK175584B1 DK175584B1 (da)	2004-12-13

Family

ID=10970243

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK199001497A DK175584B1 (da)	1988-10-20	1990-06-19	0-(3-amino-2-hydroxypropyl)-hydroximsyrehalogenider og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende en eller flere af halogeniderne og disses anvendelse

Country Status (20)

Country	Link
US (3)	US5147879A (da)
EP (1)	EP0417210B1 (da)
JP (1)	JPH0819078B2 (da)
KR (1)	KR0154117B1 (da)
AU (1)	AU620460B2 (da)
CA (1)	CA2000830C (da)
DE (1)	DE68913737T2 (da)
DK (1)	DK175584B1 (da)
ES (1)	ES2020030A6 (da)
FI (1)	FI93214C (da)
GR (1)	GR1002253B (da)
HU (1)	HU207988B (da)
IE (1)	IE65113B1 (da)
IL (1)	IL92000A (da)
NO (1)	NO178148C (da)
PL (1)	PL164547B1 (da)
PT (1)	PT92041B (da)
RU (1)	RU2093508C1 (da)
UA (1)	UA34412C2 (da)
WO (1)	WO1990004584A1 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE170170T1 (de) *	1994-05-06	1998-09-15	Biorex Kutato Fejlesztoe Kft	Hydroximsäurederivate, diese enthaltende pharmazeutische zubereitungen und verfahren zu deren herstellung
US5665756A (en) *	1994-08-03	1997-09-09	Hoechst Marion Roussel, Inc.	Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders
HU9502843D0 (en) *	1995-09-29	1995-11-28	Livigene Ltd	Pharmaceutical composition
HU222994B1 (hu)	1995-11-02	2004-01-28	BIOREX Kutató és Fejlesztő Rt.	Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására
US6884424B2 (en)	1995-12-22	2005-04-26	N-Gene Research Laboratories Inc.	Method for treating the pathological lesions of the skin that develop by ultraviolet radiation of the sunlight
HUT78138A (hu) *	1995-12-22	2000-09-28	BIOREX Kutató és Fejlesztő Rt	Hidroximsavszármazékot tartalmazó készítmény a növénytermesztés elősegítésére és alkalmazása
AU745987B2 (en) *	1995-12-22	2002-04-11	N-Gene Research Laboratories Inc.	A cosmetic composition and a method for reducing the ageing processes of skin
US6458371B1 (en)	1995-12-22	2002-10-01	Medgene, Limited	Cosmetic composition and a method for the prevention and/or reduction of the photoaging processes of the skin
HUT78139A (hu) *	1995-12-22	2000-11-28	BIOREX Kutató és Fejlesztő Rt.	Készítmény, különösen a bőr öregedési folyamatainak mérséklésére
DE19607960A1 (de) *	1996-03-01	1997-09-04	Hoechst Schering Agrevo Gmbh	Verfahren zur Herstellung von Ketonoximether durch Boronsäurekupplung
GB9613339D0 (en) *	1996-06-26	1996-08-28	Kritzinger Ann C	Limp bookbinding assembly technique for two books in one pass
UA64716C2 (en) *	1996-08-09	2004-03-15		Pharmaceuticals for therapy or prevention of illnesses connected with dysfunction of vascular endothelial cells
HU220971B1 (hu) *	1997-04-03	2002-07-29	BIOREX Kutató és Fejlesztő Rt.	Eljárás 0-(3-amino-2-hidroxi-propil)-hidroximsav-halogenidek előállítására
HU9701081D0 (en)	1997-06-23	1997-08-28	Gene Research Lab Inc N	Pharmaceutical composition of antitumoral activity
WO2000007580A2 (en) *	1998-08-03	2000-02-17	N-Gene Kutató Kft.	Pharmaceutical compositions against autoimmune diseases
HUP9900475D0 (en) *	1999-02-26	1999-04-28	Biorex Kutato Fejlesztoe Kft	O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component
US6933104B1 (en)	1999-04-23	2005-08-23	Shiva Biomedical, Llc	Diagnosis and treatment of human kidney diseases
HUP0001583A2 (hu) *	2000-04-18	2002-11-28	BIOREX Kutató és Fejlesztő Rt.	Egy piridin-1-oxid-származék és eljárás annak átalakítására gyógyászati hatású vegyületekké
DK1408966T3 (da) *	2001-07-17	2008-06-16	N Gene Res Lab Inc	Synergistiske farmaceutiske kombinationer til forebyggelse eller behandling af diabetes
HUP0105205A2 (hu) *	2001-11-29	2003-08-28	BIOREX Kutató és Fejlesztő Rt.	Metformint és egy hidroxilaminszármazékot tartalmazó, gyógyászati készítmény
CN1279889C (zh) *	2001-12-21	2006-10-18	罗迪亚公司	稳定混合的阳离子和阴离子表面活性剂组合物
AU2003202104B8 (en) *	2002-01-11	2008-10-02	Cytrx Corporation	Carboxamidine derivatives and their use in the treatment of vascular diseases
HUP0303584A3 (en) *	2003-10-30	2009-12-28	Cytrx Corp	Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases
DE10351448A1 (de) *	2003-11-04	2005-06-09	Bayer Healthcare Ag	Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
US20080227813A1 (en) *	2006-09-26	2008-09-18	Jack Raymond Barber	Pharmaceutical compositions and methods for treating diseases associated with neurodegeneration
US7763601B2 (en) *	2006-11-02	2010-07-27	N-Gene Research Laboratories, Inc.	Prevention and treatment of obesity
EA201100805A1 (ru)	2008-11-18	2011-10-31	Сантен Фармасьютикал Ко., Лтд.	Терапевтический агент при хориоретинальном дегенеративном заболевании, содержащий в качестве активного ингредиента производное пиридин-3-карбальдегид-o-(пиперидин-1-илпропил)оксима
HUP1100535A2 (en)	2011-09-26	2013-04-29	Bracelia Invest Ltd	Pharmaceutical composition for enhancement of stem cell treatment
HUP1100534A2 (en)	2011-09-26	2013-04-29	Balazs Dr Hazay	Pharmaceutical composition for the treatment of muscle atrophy
BR112020005732A2 (pt)	2017-09-22	2020-10-27	The University Of Adelaide	métodos e produtos para melhorar a qualidade de espermatozoides
KR101995300B1 (ko)	2018-03-30	2019-10-17	주식회사 아세아텍	다목적 관리기용 작업기 탈부착장치
HUP1800298A1 (hu)	2018-08-30	2020-05-28	N Gene Res Laboratories Inc	Gyógyszerkombináció béta-receptor blokkolók hatásának módosítására és a mellékhatások csökkentésére
CN112174853B (zh) *	2020-11-03	2023-07-25	湖南经世新材料有限责任公司	一种氨解法制备（z）-n-羟基苯脒的方法
KR20230128462A (ko)	2020-11-19	2023-09-05	제브라 덴마크 에이/에스	아리모클로몰 시트레이트 및 이의 중간체를 제조하기 위한 공정
KR20240070616A (ko) *	2021-09-28	2024-05-21	제브라 덴마크 에이/에스	옥심 및 gba 관련 질환의 치료에서의 이의 용도
AU2023454616A1 (en)	2023-07-10	2026-01-22	N-Gene Research Laboratories, Inc.	Increasing telomere length and/or suppressing telomere shortening

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1670497C3 (de) *	1967-06-06	1973-12-20	Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt, Budapest	Isochinohnderivate und Verfahren zu deren Herstellung
HU177578B (en) *	1976-08-27	1981-11-28	Chinoin Gyogyszer Es Vegyeszet	Process for preparing new 0-/3-amino-2-hydroxy-propyl/-amidoxime derivatives
US4187220A (en) *	1977-08-30	1980-02-05	Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T.	New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same
US4308399A (en) *	1977-08-30	1981-12-29	Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.	O-(3-Amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same
EP0369944A1 (de) *	1988-11-18	1990-05-23	Ciba-Geigy Ag	Substituierte Oxadiaminobutane
FR2639942B1 (fr) *	1988-12-02	1991-03-29	Sanofi Sa	Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant
HUT54347A (en) *	1989-01-10	1991-02-28	Chinoin Gyogyszer Es Vegyeszet	Improved process for producing amidoximes

1988
- 1988-10-20 HU HU885405A patent/HU207988B/hu unknown
1989
- 1989-10-16 IL IL9200089A patent/IL92000A/en not_active IP Right Cessation
- 1989-10-17 CA CA002000830A patent/CA2000830C/en not_active Expired - Lifetime
- 1989-10-19 WO PCT/HU1989/000048 patent/WO1990004584A1/en not_active Ceased
- 1989-10-19 PL PL89281898A patent/PL164547B1/pl unknown
- 1989-10-19 RU SU894830570A patent/RU2093508C1/ru active
- 1989-10-19 JP JP1510821A patent/JPH0819078B2/ja not_active Expired - Fee Related
- 1989-10-19 IE IE336489A patent/IE65113B1/en not_active IP Right Cessation
- 1989-10-19 US US07/499,318 patent/US5147879A/en not_active Expired - Lifetime
- 1989-10-19 EP EP89911590A patent/EP0417210B1/en not_active Expired - Lifetime
- 1989-10-19 PT PT92041A patent/PT92041B/pt not_active IP Right Cessation
- 1989-10-19 AU AU44186/89A patent/AU620460B2/en not_active Expired
- 1989-10-19 DE DE68913737T patent/DE68913737T2/de not_active Expired - Lifetime
- 1989-10-19 KR KR1019900701346A patent/KR0154117B1/ko not_active Expired - Fee Related
- 1989-10-19 GR GR890100669A patent/GR1002253B/el not_active IP Right Cessation
- 1989-10-19 UA UA4830570A patent/UA34412C2/uk unknown
- 1989-10-20 ES ES8903542A patent/ES2020030A6/es not_active Expired - Fee Related
1990
- 1990-06-18 NO NO902703A patent/NO178148C/no unknown
- 1990-06-19 DK DK199001497A patent/DK175584B1/da not_active IP Right Cessation
- 1990-06-19 FI FI903075A patent/FI93214C/fi active IP Right Grant
1992
- 1992-07-01 US US07/906,402 patent/US5296606A/en not_active Expired - Lifetime
1993
- 1993-06-07 US US08/072,765 patent/US5328906A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
HUT54110A (en)	1991-01-28
US5328906A (en)	1994-07-12
NO178148C (no)	1996-01-31
WO1990004584A1 (en)	1990-05-03
DK149790A (da)	1990-06-19
IL92000A (en)	1994-06-24
US5147879A (en)	1992-09-15
HU207988B (en)	1993-07-28
PT92041B (pt)	1995-07-18
PL164547B1 (pl)	1994-08-31
EP0417210B1 (en)	1994-03-09
US5296606A (en)	1994-03-22
PT92041A (pt)	1990-04-30
ES2020030A6 (es)	1991-07-16
AU4418689A (en)	1990-05-14
UA34412C2 (uk)	2001-03-15
NO178148B (no)	1995-10-23
JPH03502931A (ja)	1991-07-04
CA2000830A1 (en)	1990-04-20
KR900701741A (ko)	1990-12-04
FI93214B (fi)	1994-11-30
FI903075A0 (fi)	1990-06-19
KR0154117B1 (ko)	1998-12-01
NO902703D0 (no)	1990-06-18
IE65113B1 (en)	1995-10-04
IE893364L (en)	1990-04-20
CA2000830C (en)	1997-09-16
GR1002253B (en)	1996-04-23
RU2093508C1 (ru)	1997-10-20
NO902703L (no)	1990-06-18
GR890100669A (el)	1990-11-29
AU620460B2 (en)	1992-02-20
DE68913737D1 (de)	1994-04-14
FI93214C (fi)	1995-03-10
DK175584B1 (da)	2004-12-13
JPH0819078B2 (ja)	1996-02-28
IL92000A0 (en)	1990-07-12
DE68913737T2 (de)	1994-07-28
EP0417210A1 (en)	1991-03-20

Publication	Publication Date	Title
DK149790D0 (da)	1990-06-19	0-(3amino-2-hydroxypropyl)-hydroximsyrehalogenider og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende en eller flere af halogeniderne og disses anvendelse
NZ222977A (en)	1990-07-26	Aminotetralins and pharmaceutical compositions; 8-substituted-2-aminotetralins and pharmaceutical compositions thereof
MX9254A (es)	1993-06-01	Hidroxialquilxantinas terciarias, procedimiento para su preparacion, agentes que las contienen y empleo
IT1238873B (it)	1993-09-04	"dispositivi e metodi per la manipolazione di strisce".
DK51493D0 (da)	1993-05-05	Laegemiddel indeholdende humant interleukin-1alfa og anvendelse af interleukin-1alfa til fremstilling af et saadant laegemiddel
DK159848C (da)	1991-05-13	7-hydroxy-1,2,3,4,4a,5,6,10b-oktahydrobenzo(f)-quinoliner eller farmaceutisk acceptable syreadditionssalte deraf samt farmaceutiske praeparater indeholdende saadanne forbindelser
DK298789A (da)	1989-12-18	Blaesestoebt flaske i et stykke og fremgangsmaade til fremstilling af samme
DK40986D0 (da)	1986-01-28	4h-1-benzopyran-4-oner og deres svovlholdige analoge, og farmaceutiske kompositioner indeholdende forbindelserne
IT8919876A0 (it)	1989-03-23	Composizioni farmaceutiche agenti in particolare sul cuore e sul cuore e sul sistema cardiovascolare e procedimento per la loro preparazione.
TR23167A (tr)	1989-06-02	Afokal huzme genisletme cihazi ve usulue
IT8767994A0 (it)	1987-11-19	Procedimento e impianto per la denaturazione di vernici
NO903844L (no)	1991-03-06	Medikamentavgivelsesblandinger basert paa biologiske celler eller komponenter derav og fremgangsmaater.
DE68902300D1 (de)	1992-09-03	Pharmazeutische loesung enthaltend salbutamol und cromoglycinsaeure.
DK567188A (da)	1989-04-13	2,2-dimethylchromenderivater og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne
DK477685D0 (da)	1985-10-18	Peptidsubstituerede heterocycliske forbindelser og anvendelse deraf som immunostimulerende eller antiinfektive forbindelser samt farmaceutiske praeparater
DK310685D0 (da)	1985-07-08	5,6-dihydro-4h-cyklopenta(b)-tiofen-6-karboxylsyrer, fremgangsmaadetil fremstilling af dem og laegemiddelpraeparat indeholdende dem
IT1199821B (it)	1989-01-05	2-cloro-12-(-3-dimetilammino-2-metilpropil)-12h-dibenzo-/d,g//1,3,6/d iossazocine otticamente attive e procedimento per la loro preparazione
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