DK1458447T3 - Kombination af cytokrom-p450-beroende proteasinhibitorer - Google Patents

Kombination af cytokrom-p450-beroende proteasinhibitorer

Info

Publication number: DK1458447T3
Authority: DK; Denmark
Prior art keywords: cytochrome; combination; protease inhibitors; dependent protease; dependent
Prior art date: 2001-12-12

Application number

DK02793018.9T

Other languages

English (en)

Inventor

Der Geest Ronald Van

Paul Stoffels

Cornelis Groen

Dirk Edward Desire Jochmans

Original Assignee

Tibotec Pharm Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-12

Filing date

2002-12-12

Publication date

2010-01-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8181408&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1458447(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-12-12 Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd

2010-01-18 Application granted granted Critical

2010-01-18 Publication of DK1458447T3 publication Critical patent/DK1458447T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Ultra Sonic Daignosis Equipment (AREA)

DK02793018.9T 2001-12-12 2002-12-12 Kombination af cytokrom-p450-beroende proteasinhibitorer DK1458447T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01204841		2001-12-12
PCT/EP2002/014277 WO2003049746A2 (en)	2001-12-12	2002-12-12	Combination of cytochome p450 dependent protease inhibitors

Publications (1)

Publication Number	Publication Date
DK1458447T3 true DK1458447T3 (da)	2010-01-18

Family

ID=8181408

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02793018.9T DK1458447T3 (da)	2001-12-12	2002-12-12	Kombination af cytokrom-p450-beroende proteasinhibitorer

Country Status (27)

Country	Link
US (1)	US20050119338A1 (da)
EP (1)	EP1458447B1 (da)
JP (1)	JP2005511723A (da)
KR (1)	KR100974921B1 (da)
CN (1)	CN100335060C (da)
AR (1)	AR037797A1 (da)
AT (1)	ATE442189T1 (da)
AU (1)	AU2002358713B2 (da)
BR (1)	BR0215043A (da)
CA (1)	CA2469343C (da)
CY (1)	CY1110604T1 (da)
DE (1)	DE60233677D1 (da)
DK (1)	DK1458447T3 (da)
ES (1)	ES2333206T3 (da)
HR (1)	HRP20040619A2 (da)
HU (1)	HUP0402644A3 (da)
IL (1)	IL162353A0 (da)
MX (1)	MXPA04005755A (da)
NO (1)	NO20042666L (da)
NZ (1)	NZ533826A (da)
PL (1)	PL373072A1 (da)
PT (1)	PT1458447E (da)
RU (1)	RU2329050C2 (da)
SI (1)	SI1458447T1 (da)
TW (1)	TWI286476B (da)
WO (1)	WO2003049746A2 (da)
ZA (1)	ZA200404633B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE353323T1 (de) *	2003-09-30	2007-02-15	Tibotec Pharm Ltd	Verfahren zur herstellung von benzoxazolsulfonamidverbindungen und zwischenprodukten davon
AU2004308712A1 (en) *	2003-12-23	2005-07-14	Tibotec Pharmaceuticals Ltd.	Self-microemulsifying drug delivery systems of a HIV protease inhibitor
CA2566340C (en) *	2004-05-07	2014-05-06	Sequoia Pharmaceuticals, Inc.	Resistance-repellent retroviral protease inhibitors
DK1765337T3 (da) *	2004-07-08	2009-01-05	Tibotec Pharm Ltd	Kombination af tenofovir, ritonavir og TMC114
DE602006008751D1 (de)	2005-02-25	2009-10-08	Tibotec Pharm Ltd	Synthese von proteaseinhibitorvorstufen
JP2008538354A (ja) *	2005-04-08	2008-10-23	キメリクス，インコーポレイテッド	ウイルス感染症およびその他の内科疾患を治療するための化合物、組成物および方法
AR053845A1 (es)	2005-04-15	2007-05-23	Tibotec Pharm Ltd	5-tiazolilmetil[(1s,2r)-3-[[(2-amino-6-benzoxazolil)sulfonil)](2-metilpropil)amino]-2-hidroxi-1-(fenilmetil)propil]carbamato como mejorador de farmacos metabolizados por el citocromo p450
AR057182A1 (es) *	2005-11-28	2007-11-21	Tibotec Pharm Ltd	Compuestos de aminofenilsulfonamida sustituida como inhibidores de proteasa del vih
AR058238A1 (es)	2005-11-28	2008-01-23	Tibotec Pharm Ltd	Compuestos y derivados de aminofenilsulfonamida sustituida como inhibidores de proteasa del vih
SG170795A1 (en) *	2005-12-30	2011-05-30	Gilead Sciences Inc	Methods for improving the pharmacokinetics of hiv integrase inhibitors
JO2841B1 (en) *	2006-06-23	2014-09-15	تيبوتيك فارماسيوتيكالز ليمتد	2-(substituted-amino) -benzothiazole sulfonamide as protease inhibitors HIV (HIV)
CN101674822A (zh) *	2006-08-18	2010-03-17	塞阔伊亚药品公司	抑制细胞色素p450的组合物和方法
CA2681718A1 (en) *	2007-03-23	2008-10-02	University Of Massachusetts	Hiv-1 protease inhibitors
UA103013C2 (uk)	2007-12-06	2013-09-10	Тиботек Фармасьютикелз	Амідні сполуки як активатори противірусних препаратів
PA8809601A1 (es)	2007-12-24	2009-07-23	Cipla Ltd	Combinación anti-retroviral
AU2009206673B2 (en)	2008-01-25	2015-04-23	Chimerix, Inc.	Methods of treating viral infections
EP2346842A1 (en)	2008-10-07	2011-07-27	Tibotec Pharmaceuticals	New amide compounds as boosters of antivirals
US8921349B2 (en)	2009-05-11	2014-12-30	Purdue Research Foundation	Compounds and methods for treating AIDS and HIV infections
JO3090B1 (ar) *	2009-12-11	2017-03-15	Janssen Sciences Ireland Uc	5- امينو-4- هيدروكسي-بنتويل اميدات
HUE032860T2 (en)	2010-02-12	2017-11-28	Chimerix Inc	A method for treating a virus infection
CA2797601A1 (en)	2010-04-26	2011-11-10	Chimerix, Inc.	Methods of treating retroviral infections and related dosage regimes
AU2011261586B2 (en) *	2010-06-01	2015-08-27	Angion Biomedica Corp.	Cytochrome P450 inhibitors and uses thereof
PL2729128T3 (pl)	2011-07-07	2017-05-31	Janssen Sciences Ireland Uc	Preparat darunawiru
PT2729130T (pt)	2011-07-07	2017-12-13	Gilead Sciences Inc	Formulações de combinação de darunavir

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU7973994A (en) *	1993-10-13	1995-05-04	Merck & Co., Inc.	Combination therapy for hiv infection
US6037157A (en) *	1995-06-29	2000-03-14	Abbott Laboratories	Method for improving pharmacokinetics
EP0915700B1 (en) *	1996-08-05	2006-03-22	Myriad Genetics, Inc.	Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors
US6180634B1 (en) *	1997-11-13	2001-01-30	Merck & Co., Inc.	Combination therapy for the treatment of AIDS
US6436989B1 (en) *	1997-12-24	2002-08-20	Vertex Pharmaceuticals, Incorporated	Prodrugs of aspartyl protease inhibitors
AU4828199A (en) *	1998-06-23	2000-01-10	Board Of Trustees Of The University Of Illinois, The	Multi-drug resistant retroviral protease inhibitors and associated methods
US7470506B1 (en) *	1998-06-23	2008-12-30	The United States Of America As Represented By The Department Of Health And Human Services	Fitness assay and associated methods
MY145265A (en) *	1998-07-20	2012-01-13	Abbott Lab	Amorphous ritonavir
TNSN00027A1 (fr) *	1999-02-12	2005-11-10	Vertex Pharma	Inhibiteurs de l'aspartyle protease
DK1159278T3 (da) *	1999-02-12	2006-04-10	Vertex Pharma	Inhibitorer af aspartylprotease

2002
- 2002-12-11 AR ARP020104805A patent/AR037797A1/es unknown
- 2002-12-11 TW TW091135882A patent/TWI286476B/zh not_active IP Right Cessation
- 2002-12-12 JP JP2003550795A patent/JP2005511723A/ja active Pending
- 2002-12-12 WO PCT/EP2002/014277 patent/WO2003049746A2/en not_active Ceased
- 2002-12-12 ES ES02793018T patent/ES2333206T3/es not_active Expired - Lifetime
- 2002-12-12 PL PL02373072A patent/PL373072A1/xx not_active IP Right Cessation
- 2002-12-12 CN CNB028249119A patent/CN100335060C/zh not_active Expired - Fee Related
- 2002-12-12 SI SI200230865T patent/SI1458447T1/sl unknown
- 2002-12-12 AU AU2002358713A patent/AU2002358713B2/en not_active Revoked
- 2002-12-12 BR BR0215043-3A patent/BR0215043A/pt not_active Application Discontinuation
- 2002-12-12 DK DK02793018.9T patent/DK1458447T3/da active
- 2002-12-12 EP EP02793018A patent/EP1458447B1/en not_active Revoked
- 2002-12-12 AT AT02793018T patent/ATE442189T1/de not_active IP Right Cessation
- 2002-12-12 DE DE60233677T patent/DE60233677D1/de not_active Expired - Lifetime
- 2002-12-12 NZ NZ533826A patent/NZ533826A/en not_active IP Right Cessation
- 2002-12-12 US US10/498,024 patent/US20050119338A1/en not_active Abandoned
- 2002-12-12 CA CA002469343A patent/CA2469343C/en not_active Expired - Fee Related
- 2002-12-12 HU HU0402644A patent/HUP0402644A3/hu unknown
- 2002-12-12 KR KR1020047008830A patent/KR100974921B1/ko not_active Ceased
- 2002-12-12 HR HR20040619A patent/HRP20040619A2/hr not_active Application Discontinuation
- 2002-12-12 IL IL16235302A patent/IL162353A0/xx unknown
- 2002-12-12 RU RU2004121144/15A patent/RU2329050C2/ru not_active IP Right Cessation
- 2002-12-12 PT PT02793018T patent/PT1458447E/pt unknown
2004
- 2004-06-10 ZA ZA200404633A patent/ZA200404633B/en unknown
- 2004-06-14 MX MXPA04005755A patent/MXPA04005755A/es active IP Right Grant
- 2004-06-24 NO NO20042666A patent/NO20042666L/no not_active Application Discontinuation
2009
- 2009-12-09 CY CY20091101283T patent/CY1110604T1/el unknown

Also Published As

Publication number	Publication date
RU2329050C2 (ru)	2008-07-20
PT1458447E (pt)	2009-12-16
KR100974921B1 (ko)	2010-08-09
TW200409624A (en)	2004-06-16
HUP0402644A3 (en)	2008-04-28
CA2469343C (en)	2008-05-13
CN100335060C (zh)	2007-09-05
RU2004121144A (ru)	2005-04-20
CA2469343A1 (en)	2003-06-19
BR0215043A (pt)	2004-11-03
AU2002358713A1 (en)	2003-06-23
SI1458447T1 (sl)	2010-01-29
AR037797A1 (es)	2004-12-01
DE60233677D1 (de)	2009-10-22
HRP20040619A2 (en)	2005-08-31
CN1604803A (zh)	2005-04-06
CY1110604T1 (el)	2015-04-29
KR20040071182A (ko)	2004-08-11
JP2005511723A (ja)	2005-04-28
HUP0402644A2 (en)	2007-02-28
WO2003049746A3 (en)	2003-12-31
PL373072A1 (en)	2005-08-08
NZ533826A (en)	2006-04-28
EP1458447B1 (en)	2009-09-09
MXPA04005755A (es)	2004-09-10
US20050119338A1 (en)	2005-06-02
ATE442189T1 (de)	2009-09-15
NO20042666L (no)	2004-09-09
AU2002358713B2 (en)	2009-01-29
EP1458447A2 (en)	2004-09-22
IL162353A0 (en)	2005-11-20
HK1070008A1 (en)	2005-06-10
WO2003049746A2 (en)	2003-06-19
TWI286476B (en)	2007-09-11
ES2333206T3 (es)	2010-02-18
ZA200404633B (en)	2005-09-01

Publication	Publication Date	Title
DK1458447T3 (da)	2010-01-18	Kombination af cytokrom-p450-beroende proteasinhibitorer
NO20034045D0 (no)	2003-09-12	Metallproteinase-inhibitorer
DE60234125D1 (de)	2009-12-03	E inhibitoren
CY2015028I1 (el)	2016-07-27	Ενας αναστολεας ν-ακυλοσφιγγοσινο γλυκοζυλοτρανσφερασης
EE200300439A (et)	2003-12-15	Metalloproteinaasi inhibiitorid
DK1438306T3 (da)	2014-06-23	Derivater af UK-2A
CY2012007I2 (el)	2014-07-02	Πεπτιδομιμητικοι αναστολεις πρωτεασης
DK1567529T4 (da)	2021-05-10	Pseudopolymorfe former af en hiv-proteaseinhibitor
PT1370553E (pt)	2006-09-29	Inibidores de rhoquinase
ATE286049T1 (de)	2005-01-15	Pyridazinonaldose reductase inhibitoren
NO20034032L (no)	2003-11-10	Metallproteinase-inhibitorer
EP1499336A4 (en)	2005-06-01	PROTEASE INHIBITORS
DK1686113T3 (da)	2012-02-20	Inhibitorer af aspartylprotease
NO20042719L (no)	2004-06-28	Substituerte 2-amino-cykloalkankarboksamider og deres anvendelse som protease-inhibitorer
FI20010558L (fi)	2002-09-20	Kappaleiden paikannus
DK1451154T3 (da)	2008-05-19	Inhibitorer af cytosolisk phospholipase A2
DK1536796T3 (da)	2008-06-09	N-arylpiperidinsubstituerede biphenylcarboxamider som inhibitorer af apolipoprotein B-sektion
ATE429431T1 (de)	2009-05-15	2-amino-benzoxazol-suphonamide als breitspektrum- hiv-protease-inhibitoren
NO20025786L (no)	2003-02-12	Protaseinhibitorer
NO20025005D0 (no)	2002-10-17	Proteaseinhibitorer
EP1463521A4 (en)	2009-06-24	INHIBITOR OF GP41
NO20032328D0 (no)	2003-05-22	Proteaseinhibitorer
DK1373898T3 (da)	2006-10-30	Påvisning af inflammationer
SE0100694D0 (sv)	2001-02-28	DHFR inhibitors
DK1319049T3 (da)	2005-03-21	Grunding af stål