DK1354054T3 - Polypeptider der kan binde til CD64, og som omfatter en eller flere heterologe T-celle-epitoper, samt anvendelser deraf - Google Patents
Polypeptider der kan binde til CD64, og som omfatter en eller flere heterologe T-celle-epitoper, samt anvendelser derafInfo
- Publication number
- DK1354054T3 DK1354054T3 DK02715584T DK02715584T DK1354054T3 DK 1354054 T3 DK1354054 T3 DK 1354054T3 DK 02715584 T DK02715584 T DK 02715584T DK 02715584 T DK02715584 T DK 02715584T DK 1354054 T3 DK1354054 T3 DK 1354054T3
- Authority
- DK
- Denmark
- Prior art keywords
- heterologous
- cell epitopes
- binding
- polypeptides capable
- cytotoxic
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 102100026122 High affinity immunoglobulin gamma Fc receptor I Human genes 0.000 title abstract 2
- 101000913074 Homo sapiens High affinity immunoglobulin gamma Fc receptor I Proteins 0.000 title abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 2
- 230000005867 T cell response Effects 0.000 abstract 2
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 2
- 244000052769 pathogen Species 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
- C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
- C07K16/4266—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Jellies, Jams, And Syrups (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0102145.0A GB0102145D0 (en) | 2001-01-26 | 2001-01-26 | Substances |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1354054T3 true DK1354054T3 (da) | 2006-02-13 |
Family
ID=9907631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02715584T DK1354054T3 (da) | 2001-01-26 | 2002-01-28 | Polypeptider der kan binde til CD64, og som omfatter en eller flere heterologe T-celle-epitoper, samt anvendelser deraf |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20040146505A1 (da) |
| EP (1) | EP1354054B1 (da) |
| JP (1) | JP5198715B2 (da) |
| KR (1) | KR20030083698A (da) |
| AT (1) | ATE307209T1 (da) |
| AU (1) | AU2002225230B2 (da) |
| CA (1) | CA2435672C (da) |
| DE (1) | DE60206731T2 (da) |
| DK (1) | DK1354054T3 (da) |
| ES (1) | ES2254663T3 (da) |
| GB (1) | GB0102145D0 (da) |
| WO (1) | WO2002058728A2 (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL371202A1 (en) * | 2002-04-09 | 2005-06-13 | Merck Patent Gmbh | Anti-idiotype anti-cea antibody molecules and its use as cancer vaccine |
| AT502293B1 (de) * | 2002-05-15 | 2008-03-15 | Igeneon Krebs Immuntherapie | Immunogener, monoklonaler antikörper |
| PT1694709E (pt) * | 2003-11-26 | 2011-03-17 | Fraunhofer Ges Forschung | Imunotoxinas anti-cd64-eta¿ recombinantes |
| JP4855163B2 (ja) | 2006-01-18 | 2012-01-18 | 新日本製鐵株式会社 | ほうろう加工品 |
| GB0605735D0 (en) * | 2006-03-22 | 2006-05-03 | Immunobiology Ltd | Composition and method for mediating an immune response |
| GB0706070D0 (en) * | 2007-03-28 | 2007-05-09 | Scancell Ltd | Nucleic acids |
| GB201214007D0 (en) | 2012-08-07 | 2012-09-19 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
| JP2018508481A (ja) | 2015-02-02 | 2018-03-29 | ザ ユニバーシティ オブ バーミンガム | 複数のｔ細胞エピトープを有する標的化部分ペプチドエピトープ複合体 |
| GB201815041D0 (en) | 2018-09-14 | 2018-10-31 | Scancell Ltd | Epitopes |
| US12016885B2 (en) | 2018-11-06 | 2024-06-25 | Alsatech, Inc. | Method of solubilizing TDP-43 protein aggregates in amyotrophic lateral sclerosis using a microvascular endothelial cell expressing an anti-TDP-43 Fab |
| GB202005779D0 (en) | 2020-04-21 | 2020-06-03 | Scancell Ltd | Anti-tumour immune responses |
| US20230310584A1 (en) | 2020-08-26 | 2023-10-05 | Scancell Limited | Nucleic acids encoding a polypeptide comprising a modified fc region of a human igg1 and at least one heterologous antigen |
| GB202018395D0 (en) | 2020-11-23 | 2021-01-06 | Scancell Ltd | Immunotherapy |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69023900T4 (de) * | 1989-02-24 | 1996-10-02 | The Regents Of The University Of California, Berkeley, Calif. | Gentechnologisch veränderte immunglobuline. |
| US5969109A (en) * | 1990-02-28 | 1999-10-19 | Bona; Constantin | Chimeric antibodies comprising antigen binding sites and B and T cell epitopes |
| WO1992018540A1 (en) * | 1991-04-18 | 1992-10-29 | Mount Sinai School Of Medicine Of The City University Of New York | Anti-human immunodeficiency virus recombinant antibodies |
| JPH10500670A (ja) | 1994-05-13 | 1998-01-20 | エクラゲン リミテッド | ペプチド送達の改良またはペプチド送達との関連 |
| US20080318254A9 (en) * | 1997-03-10 | 2008-12-25 | The Regents Of The University Of California | PSCA antibodies and hybridomas producing them |
| ATE501175T1 (de) * | 1999-04-27 | 2011-03-15 | Nevagen Llc | Somatische transgene immunisierung und darauf bezogene verfahren |
| SK782002A3 (en) | 1999-07-21 | 2003-08-05 | Lexigen Pharm Corp | FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
| US7067110B1 (en) * | 1999-07-21 | 2006-06-27 | Emd Lexigen Research Center Corp. | Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
| US20040248113A1 (en) * | 1999-12-28 | 2004-12-09 | Alessandro Sette | Method and system for optimizing multi-epitope nucleic acid constructs and peptides encoded thereby |
-
2001
- 2001-01-26 GB GBGB0102145.0A patent/GB0102145D0/en not_active Ceased
-
2002
- 2002-01-28 WO PCT/GB2002/000354 patent/WO2002058728A2/en not_active Ceased
- 2002-01-28 AU AU2002225230A patent/AU2002225230B2/en not_active Expired
- 2002-01-28 ES ES02715584T patent/ES2254663T3/es not_active Expired - Lifetime
- 2002-01-28 US US10/470,045 patent/US20040146505A1/en not_active Abandoned
- 2002-01-28 DK DK02715584T patent/DK1354054T3/da active
- 2002-01-28 DE DE60206731T patent/DE60206731T2/de not_active Expired - Lifetime
- 2002-01-28 JP JP2002559062A patent/JP5198715B2/ja not_active Expired - Lifetime
- 2002-01-28 KR KR10-2003-7009871A patent/KR20030083698A/ko not_active Withdrawn
- 2002-01-28 CA CA2435672A patent/CA2435672C/en not_active Expired - Lifetime
- 2002-01-28 AT AT02715584T patent/ATE307209T1/de active
- 2002-01-28 EP EP02715584A patent/EP1354054B1/en not_active Expired - Lifetime
-
2010
- 2010-08-18 US US12/805,752 patent/US8187600B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20040146505A1 (en) | 2004-07-29 |
| DE60206731T2 (de) | 2006-07-20 |
| WO2002058728A2 (en) | 2002-08-01 |
| AU2002225230B2 (en) | 2007-08-16 |
| EP1354054A2 (en) | 2003-10-22 |
| CA2435672A1 (en) | 2002-08-01 |
| ES2254663T3 (es) | 2006-06-16 |
| US8187600B2 (en) | 2012-05-29 |
| DE60206731D1 (de) | 2006-03-02 |
| JP5198715B2 (ja) | 2013-05-15 |
| KR20030083698A (ko) | 2003-10-30 |
| WO2002058728A3 (en) | 2002-10-03 |
| GB0102145D0 (en) | 2001-03-14 |
| EP1354054B1 (en) | 2005-10-19 |
| JP2004520376A (ja) | 2004-07-08 |
| ATE307209T1 (de) | 2005-11-15 |
| CA2435672C (en) | 2013-10-29 |
| US20110165180A1 (en) | 2011-07-07 |
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