DK1216036T3 - Transdermal administration af N-(2,5-disubstitueret phenyl)-N'-(3-substitueret phenyl)-N'-methylguanidin - Google Patents
Transdermal administration af N-(2,5-disubstitueret phenyl)-N'-(3-substitueret phenyl)-N'-methylguanidinInfo
- Publication number
- DK1216036T3 DK1216036T3 DK00964953T DK00964953T DK1216036T3 DK 1216036 T3 DK1216036 T3 DK 1216036T3 DK 00964953 T DK00964953 T DK 00964953T DK 00964953 T DK00964953 T DK 00964953T DK 1216036 T3 DK1216036 T3 DK 1216036T3
- Authority
- DK
- Denmark
- Prior art keywords
- phenyl
- transdermal administration
- methylguanidine
- guanidine
- substituted phenyl
- Prior art date
Links
- -1 N- (2,5-disubstituted phenyl) -N '- (3-substituted phenyl) -N'-methylguanidine Chemical class 0.000 title abstract 3
- ZRALSGWEFCBTJO-UHFFFAOYSA-N anhydrous guanidine Natural products NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 2
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 238000007675 cardiac surgery Methods 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 230000003557 neuropsychological effect Effects 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15399699P | 1999-09-15 | 1999-09-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1216036T3 true DK1216036T3 (da) | 2006-03-27 |
Family
ID=22549595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00964953T DK1216036T3 (da) | 1999-09-15 | 2000-09-08 | Transdermal administration af N-(2,5-disubstitueret phenyl)-N'-(3-substitueret phenyl)-N'-methylguanidin |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20030198662A1 (da) |
| EP (1) | EP1216036B1 (da) |
| AT (1) | ATE309791T1 (da) |
| AU (1) | AU7576000A (da) |
| CA (1) | CA2384986A1 (da) |
| DE (1) | DE60024111T2 (da) |
| DK (1) | DK1216036T3 (da) |
| ES (1) | ES2249296T3 (da) |
| WO (1) | WO2001019352A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004062614B4 (de) * | 2004-12-24 | 2011-12-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung |
| CA2916183C (en) * | 2013-07-03 | 2022-03-29 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system with electronic component |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1076799A (en) * | 1997-10-10 | 1999-05-03 | Cambridge Neuroscience, Inc. | Pharmaceutically active compound and methods of use |
-
2000
- 2000-09-08 AT AT00964953T patent/ATE309791T1/de not_active IP Right Cessation
- 2000-09-08 DE DE60024111T patent/DE60024111T2/de not_active Expired - Lifetime
- 2000-09-08 EP EP00964953A patent/EP1216036B1/en not_active Expired - Lifetime
- 2000-09-08 ES ES00964953T patent/ES2249296T3/es not_active Expired - Lifetime
- 2000-09-08 AU AU75760/00A patent/AU7576000A/en not_active Abandoned
- 2000-09-08 DK DK00964953T patent/DK1216036T3/da active
- 2000-09-08 CA CA002384986A patent/CA2384986A1/en not_active Abandoned
- 2000-09-08 WO PCT/US2000/024682 patent/WO2001019352A1/en not_active Ceased
-
2003
- 2003-04-11 US US10/412,104 patent/US20030198662A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60024111D1 (de) | 2005-12-22 |
| ES2249296T3 (es) | 2006-04-01 |
| ATE309791T1 (de) | 2005-12-15 |
| AU7576000A (en) | 2001-04-17 |
| DE60024111T2 (de) | 2006-03-30 |
| US20030198662A1 (en) | 2003-10-23 |
| EP1216036A1 (en) | 2002-06-26 |
| WO2001019352A1 (en) | 2001-03-22 |
| EP1216036B1 (en) | 2005-11-16 |
| CA2384986A1 (en) | 2001-03-22 |
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