DK111188D0 - INTERMEDIATES FOR USE IN THE PRODUCTION OF VITAMIN-D DERIVATIVES - Google Patents

INTERMEDIATES FOR USE IN THE PRODUCTION OF VITAMIN-D DERIVATIVES

Info

Publication number: DK111188D0
Authority: DK; Denmark
Prior art keywords: intermediates; vitamin; derivatives; production
Prior art date: 1984-10-04

Application number

DK111188A

Other languages

Danish (da)

Other versions

DK159389B (en

DK111188A (en

DK159389C (en

Inventor

Hector F Deluca

Nobuo Ikekawa

Yoko Tanaka

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-04

Filing date

1988-03-02

Publication date

1988-03-02

1988-03-02 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

1988-03-02 Publication of DK111188A publication Critical patent/DK111188A/en

1988-03-02 Publication of DK111188D0 publication Critical patent/DK111188D0/en

1990-10-08 Publication of DK159389B publication Critical patent/DK159389B/en

1991-03-11 Application granted granted Critical

1991-03-11 Publication of DK159389C publication Critical patent/DK159389C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK111188A 1984-10-04 1988-03-02 CHOLESTAGE STAGE OR TRIEND DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF 24-HOMOVITAMIN-D3 DERIVATIVES DK159389C (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US65754984A	1984-10-04	1984-10-04
US65754984		1984-10-04
PCT/US1985/001571 WO1986002078A1 (en)	1984-10-04	1985-08-19	Vitamin d derivatives and methods for preparing same
US8501571		1985-08-19

Publications (4)

Publication Number	Publication Date
DK111188A DK111188A (en)	1988-03-02
DK111188D0 true DK111188D0 (en)	1988-03-02
DK159389B DK159389B (en)	1990-10-08
DK159389C DK159389C (en)	1991-03-11

Family

ID=24637652

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
DK260086A DK154290C (en)	1984-10-04	1986-06-03	VITAMIN-D DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE
DK111188A DK159389C (en)	1984-10-04	1988-03-02	CHOLESTAGE STAGE OR TRIEND DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF 24-HOMOVITAMIN-D3 DERIVATIVES
DK177489A DK158989C (en)	1984-10-04	1989-04-13	CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015390A DK158991C (en)	1984-10-04	1990-01-19	CHOLE STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015290A DK158990C (en)	1984-10-04	1990-01-19	CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK260086A DK154290C (en)	1984-10-04	1986-06-03	VITAMIN-D DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
DK177489A DK158989C (en)	1984-10-04	1989-04-13	CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015390A DK158991C (en)	1984-10-04	1990-01-19	CHOLE STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015290A DK158990C (en)	1984-10-04	1990-01-19	CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES

Country Status (13)

Country	Link
EP (1)	EP0197949A1 (en)
JP (3)	JPS62500301A (en)
AU (2)	AU582789B2 (en)
BE (1)	BE903376A (en)
CH (1)	CH672920A5 (en)
DE (2)	DE3590488C2 (en)
DK (5)	DK154290C (en)
FR (1)	FR2571369B1 (en)
GB (2)	GB2167070B (en)
IE (1)	IE58104B1 (en)
IT (1)	IT1190401B (en)
NL (1)	NL8520265A (en)
WO (1)	WO1986002078A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5206229A (en) *	1988-04-21	1993-04-27	Leo Pharmaceutical Products Ltd	Vitamin d analogues
US4927815A (en) *	1988-04-29	1990-05-22	Wisconsin Alumni Research Foundation	Compounds effective in inducing cell differentiation and process for preparing same
AU629831B2 (en) *	1988-04-29	1992-10-15	Wisconsin Alumni Research Foundation	Side chain unsaturated 1 alpha-hydroxyvitamin d homologs for the treatment of leukemia
GB2229921B (en) *	1989-04-05	1992-12-16	Chugai Pharmaceutical Co Ltd	Treatment for hyperparathyroidism with use of vitamin d derivatives
DE3933034A1 (en) *	1989-10-02	1991-04-11	Schering Ag	24-HOMO-VITAMIN-D DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF
US5260290A (en) *	1990-02-14	1993-11-09	Wisconsin Alumni Research Foundation	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) *	1990-02-14	1991-07-09	Deluca Hector F	Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5891865A (en) *	1996-10-04	1999-04-06	Wisconsin Alumni Research Foundation	Treatment of arthritic disease induced by infectious agents
JP2008519808A (en)	2004-11-12	2008-06-12	ビオエクセルエスピーエー	Combination of vitamin D derivatives and antiproliferative drugs for the treatment of bladder cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3833622A (en) *	1969-03-17	1974-09-03	Upjohn Co	Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3880894A (en) *	1974-05-24	1975-04-29	Wisconsin Alumni Res Found	1,25-Dihydroxyergocalciferol
US4226770A (en)	1978-02-10	1980-10-07	Kaiser Emil T	Synthesis of steroids
US4163744A (en)	1978-02-10	1979-08-07	Kaiser Emil T	Synthesis of steroids
AU527805B2 (en) *	1978-07-27	1983-03-24	Research Institute For Medicine And Chemistry Inc.	1alpha, 1beta dihydroxy steroid-5-enes
US4225596A (en) *	1978-10-13	1980-09-30	Wisconsin Alumni Research Foundation	Method for treating calcium imbalance and improving calcium absorption in mammals
US4448721A (en) *	1982-09-20	1984-05-15	Wisconsin Alumni Research Foundation	Hydroxyvitamin D2 compounds and process for preparing same
US4508651A (en) *	1983-03-21	1985-04-02	Hoffmann-La Roche Inc.	Synthesis of 1α,25-dihydroxyergocalciferol
WO1984004527A1 (en) *	1983-05-09	1984-11-22	Wisconsin Alumni Res Found	PROCESS FOR THE PREPARATION OF 1alpha,25-DIHYDROXYLATED VITAMIN D2 AND RELATED COMPOUNDS

1985
- 1985-08-19 CH CH2351/86A patent/CH672920A5/de not_active IP Right Cessation
- 1985-08-19 AU AU47761/85A patent/AU582789B2/en not_active Ceased
- 1985-08-19 JP JP60503924A patent/JPS62500301A/en active Granted
- 1985-08-19 EP EP85904336A patent/EP0197949A1/en not_active Withdrawn
- 1985-08-19 DE DE3590488A patent/DE3590488C2/de not_active Expired - Lifetime
- 1985-08-19 DE DE19853590488 patent/DE3590488T/en active Pending
- 1985-08-19 WO PCT/US1985/001571 patent/WO1986002078A1/en not_active Ceased
- 1985-08-19 NL NL8520265A patent/NL8520265A/en unknown
- 1985-10-04 BE BE0/215682A patent/BE903376A/en not_active IP Right Cessation
- 1985-10-04 GB GB08524479A patent/GB2167070B/en not_active Expired
- 1985-10-04 IT IT22359/85A patent/IT1190401B/en active
- 1985-10-04 FR FR8514758A patent/FR2571369B1/en not_active Expired
- 1985-10-04 IE IE244385A patent/IE58104B1/en not_active IP Right Cessation
1986
- 1986-06-03 DK DK260086A patent/DK154290C/en active
1987
- 1987-04-23 GB GB08709579A patent/GB2188932B/en not_active Expired
1988
- 1988-03-02 DK DK111188A patent/DK159389C/en active
- 1988-12-29 AU AU27614/88A patent/AU605007B2/en not_active Ceased
1989
- 1989-04-13 DK DK177489A patent/DK158989C/en active
1990
- 1990-01-19 DK DK015390A patent/DK158991C/en active
- 1990-01-19 DK DK015290A patent/DK158990C/en active
1992
- 1992-05-19 JP JP4150044A patent/JPH0635475B2/en not_active Expired - Lifetime
- 1992-05-19 JP JP4150045A patent/JPH0689022B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DK260086D0 (en)	1986-06-03
CH672920A5 (en)	1990-01-15
JPH0635475B2 (en)	1994-05-11
GB8709579D0 (en)	1987-05-28
DE3590488C2 (en)	1992-10-01
NL8520265A (en)	1986-09-01
IE58104B1 (en)	1993-06-30
BE903376A (en)	1986-02-03
IT1190401B (en)	1988-02-16
DK158990C (en)	1991-01-21
DK15290A (en)	1990-01-19
AU605007B2 (en)	1991-01-03
DK158991C (en)	1991-01-21
DK158989B (en)	1990-08-13
DK159389B (en)	1990-10-08
GB2167070A (en)	1986-05-21
DK177489A (en)	1989-04-13
JPS62500301A (en)	1987-02-05
WO1986002078A1 (en)	1986-04-10
DK154290B (en)	1988-10-31
FR2571369B1 (en)	1987-12-04
DK158990B (en)	1990-08-13
DK111188A (en)	1988-03-02
JPH0689022B2 (en)	1994-11-09
DE3590488T (en)	1986-10-09
AU4776185A (en)	1986-04-17
AU582789B2 (en)	1989-04-13
DK158991B (en)	1990-08-13
JPH0569103B2 (en)	1993-09-30
JPH05222089A (en)	1993-08-31
DK15390A (en)	1990-01-19
DK154290C (en)	1989-03-28
IT8522359A0 (en)	1985-10-04
GB2167070B (en)	1988-09-01
DK15390D0 (en)	1990-01-19
EP0197949A1 (en)	1986-10-22
AU2761488A (en)	1989-06-08
GB8524479D0 (en)	1985-11-06
GB2188932B (en)	1988-09-01
DK159389C (en)	1991-03-11
DK260086A (en)	1986-06-03
DK158989C (en)	1991-01-21
IE852443L (en)	1986-04-04
DK177489D0 (en)	1989-04-13
JPH05178887A (en)	1993-07-20
DK15290D0 (en)	1990-01-19
GB2188932A (en)	1987-10-14
FR2571369A1 (en)	1986-04-11

Publication	Publication Date	Title
DK168985D0 (en)	1985-04-15	PROCEDURE FOR THE PRODUCTION OF ZEOLITE-BETA
DK38385D0 (en)	1985-01-28	PROCEDURE FOR THE PRODUCTION OF SYNTHESIC GAS
FR2562812B1 (en)	1987-07-17	SHOWER
DK184588D0 (en)	1988-04-06	INTERMEDIATES FOR USE IN THE PREPARATION OF 1ALFA, 25-DIHYDROXYLERED VITAMIN D2 DERIVATIVES
DK129085A (en)	1985-09-23	PROCEDURE FOR THE PRODUCTION OF PROTEINS
DK621589A (en)	1989-12-08	INTERMEDIATES FOR THE SYNTHESIS OF THE UNKNOWN UNKNOWN 4-CYANOPYRIDAZINES
LV10436A (en)	1995-02-20	Azole derivatives and intermediates for their production
DK111188A (en)	1988-03-02	INTERMEDIATES FOR USE IN THE PRODUCTION OF VITAMIN-D DERIVATIVES
DK416888A (en)	1988-07-25	CEPHALOSPORINE COMPOUNDS, CRYSTALLINIC DERIVATIVES THEREOF, INTERMEDIATES FOR USE IN THE PRODUCTION OF CEPHALOSPORINE COMPOUNDS AND PROCEDURES FOR THE PRODUCTION OF CEPHALOSPORINE COMPOUNDS
FI854603A7 (en)	1986-05-25	Process and intermediates for the preparation of 5-alkyl-1-phenyl-2-piperazino-alkylpyrazolin-3-one compounds.
IT1185514B (en)	1987-11-12	PROMEDICINALS OF ANTI-INFLAMMATORY OSSICAM
DK56490D0 (en)	1990-03-05	HOMOCHOL STANDARD DERIVATIVES AS INTERMEDIATES FOR USE IN THE PREPARATION OF 26-HOMOVITAMIN D3 DERIVATIVES
IT1186758B (en)	1987-12-16	PROCEDURE FOR THE PRODUCTION OF EXPANDABLE POLYSTYRENE
IT1145214B (en)	1986-11-05	SFIBRATORE FOR THE PRODUCTION OF PASTALEGNO
DK382886D0 (en)	1986-08-11	PROCEDURE FOR THE PRODUCTION OF HORMONFACTOR DERIVATIVES
DK40485A (en)	1985-09-03	Prostaglandin intermediates
DK312988A (en)	1988-12-11	PROCEDURE FOR THE PRODUCTION OF ZIDOVUDIN AND INTERMEDIATES OF THE PROCEDURE
IT1162485B (en)	1987-04-01	PROCEDURE FOR THE PRODUCTION OF REPLACED PYRIDINS
FI855066A7 (en)	1986-06-27	Production of phosphorus-containing intermediates for use in herbicides.
DK559786A (en)	1987-05-22	INTERMEDIATES FOR THE PREPARATION OF BETA-LACTAMANTIBIOTICS
DK145685A (en)	1985-10-03	PROCEDURE FOR THE PREPARATION OF 4-ACETYLIMIDAZOLD DERIVATIVES AND INTERMEDIATES FOR USING THE PROCEDURE
DK212285D0 (en)	1985-05-14	PROCEDURE FOR THE PRODUCTION OF RIBOFLAVIN AND INTERMEDIATES FOR USE IN THE PROCEDURE
ATA88386A (en)	1987-04-15	SHOWER
ATA380184A (en)	1986-05-15	SHOWER HEAD
NO166081C (en)	1991-05-29	INTERMEDIATES FOR USE IN THE PREPARATION OF IMIDAZOKINOLIN DERIVATIVES