AU2761488A - Steroidal compounds and process for lengthening the side-chain of certain steroids - Google Patents

Steroidal compounds and process for lengthening the side-chain of certain steroids

Info

Publication number: AU2761488A
Authority: AU; Australia
Prior art keywords: lengthening; chain; steroidal compounds; certain steroids; steroids
Prior art date: 1984-10-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU27614/88A

Other versions

AU605007B2 (en

Inventor

Hector F. Deluca

Nobuo Ikekawa

Yoko Tanaka

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wisconsin Alumni Research Foundation

Original Assignee

Wisconsin Alumni Research Foundation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-04

Filing date

1988-12-29

Publication date

1989-06-08

1988-12-29 Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation

1989-06-08 Publication of AU2761488A publication Critical patent/AU2761488A/en

1991-01-03 Application granted granted Critical

1991-01-03 Publication of AU605007B2 publication Critical patent/AU605007B2/en

2005-08-19 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AU27614/88A 1984-10-04 1988-12-29 Steroidal compounds and process for lengthening the side-chain of certain steroids Ceased AU605007B2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US65754984A	1984-10-04	1984-10-04
US657549		1984-10-04

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
AU47761/85A Division AU582789B2 (en)	1984-10-04	1985-08-19	Vitamin d derivatives and methods for preparing same

Publications (2)

Publication Number	Publication Date
AU2761488A true AU2761488A (en)	1989-06-08
AU605007B2 AU605007B2 (en)	1991-01-03

Family

ID=24637652

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AU47761/85A Ceased AU582789B2 (en)	1984-10-04	1985-08-19	Vitamin d derivatives and methods for preparing same
AU27614/88A Ceased AU605007B2 (en)	1984-10-04	1988-12-29	Steroidal compounds and process for lengthening the side-chain of certain steroids

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AU47761/85A Ceased AU582789B2 (en)	1984-10-04	1985-08-19	Vitamin d derivatives and methods for preparing same

Country Status (13)

Country	Link
EP (1)	EP0197949A1 (en)
JP (3)	JPS62500301A (en)
AU (2)	AU582789B2 (en)
BE (1)	BE903376A (en)
CH (1)	CH672920A5 (en)
DE (2)	DE3590488C2 (en)
DK (5)	DK154290C (en)
FR (1)	FR2571369B1 (en)
GB (2)	GB2167070B (en)
IE (1)	IE58104B1 (en)
IT (1)	IT1190401B (en)
NL (1)	NL8520265A (en)
WO (1)	WO1986002078A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5206229A (en) *	1988-04-21	1993-04-27	Leo Pharmaceutical Products Ltd	Vitamin d analogues
US4927815A (en) *	1988-04-29	1990-05-22	Wisconsin Alumni Research Foundation	Compounds effective in inducing cell differentiation and process for preparing same
AU629831B2 (en) *	1988-04-29	1992-10-15	Wisconsin Alumni Research Foundation	Side chain unsaturated 1 alpha-hydroxyvitamin d homologs for the treatment of leukemia
GB2229921B (en) *	1989-04-05	1992-12-16	Chugai Pharmaceutical Co Ltd	Treatment for hyperparathyroidism with use of vitamin d derivatives
DE3933034A1 (en) *	1989-10-02	1991-04-11	Schering Ag	24-HOMO-VITAMIN-D DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF
US5260290A (en) *	1990-02-14	1993-11-09	Wisconsin Alumni Research Foundation	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) *	1990-02-14	1991-07-09	Deluca Hector F	Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5891865A (en) *	1996-10-04	1999-04-06	Wisconsin Alumni Research Foundation	Treatment of arthritic disease induced by infectious agents
JP2008519808A (en)	2004-11-12	2008-06-12	ビオエクセルエスピーエー	Combination of vitamin D derivatives and antiproliferative drugs for the treatment of bladder cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3833622A (en) *	1969-03-17	1974-09-03	Upjohn Co	Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3880894A (en) *	1974-05-24	1975-04-29	Wisconsin Alumni Res Found	1,25-Dihydroxyergocalciferol
US4226770A (en)	1978-02-10	1980-10-07	Kaiser Emil T	Synthesis of steroids
US4163744A (en)	1978-02-10	1979-08-07	Kaiser Emil T	Synthesis of steroids
AU527805B2 (en) *	1978-07-27	1983-03-24	Research Institute For Medicine And Chemistry Inc.	1alpha, 1beta dihydroxy steroid-5-enes
US4225596A (en) *	1978-10-13	1980-09-30	Wisconsin Alumni Research Foundation	Method for treating calcium imbalance and improving calcium absorption in mammals
US4448721A (en) *	1982-09-20	1984-05-15	Wisconsin Alumni Research Foundation	Hydroxyvitamin D2 compounds and process for preparing same
US4508651A (en) *	1983-03-21	1985-04-02	Hoffmann-La Roche Inc.	Synthesis of 1α,25-dihydroxyergocalciferol
WO1984004527A1 (en) *	1983-05-09	1984-11-22	Wisconsin Alumni Res Found	PROCESS FOR THE PREPARATION OF 1alpha,25-DIHYDROXYLATED VITAMIN D2 AND RELATED COMPOUNDS

1985
- 1985-08-19 CH CH2351/86A patent/CH672920A5/de not_active IP Right Cessation
- 1985-08-19 AU AU47761/85A patent/AU582789B2/en not_active Ceased
- 1985-08-19 JP JP60503924A patent/JPS62500301A/en active Granted
- 1985-08-19 EP EP85904336A patent/EP0197949A1/en not_active Withdrawn
- 1985-08-19 DE DE3590488A patent/DE3590488C2/de not_active Expired - Lifetime
- 1985-08-19 DE DE19853590488 patent/DE3590488T/en active Pending
- 1985-08-19 WO PCT/US1985/001571 patent/WO1986002078A1/en not_active Ceased
- 1985-08-19 NL NL8520265A patent/NL8520265A/en unknown
- 1985-10-04 BE BE0/215682A patent/BE903376A/en not_active IP Right Cessation
- 1985-10-04 GB GB08524479A patent/GB2167070B/en not_active Expired
- 1985-10-04 IT IT22359/85A patent/IT1190401B/en active
- 1985-10-04 FR FR8514758A patent/FR2571369B1/en not_active Expired
- 1985-10-04 IE IE244385A patent/IE58104B1/en not_active IP Right Cessation
1986
- 1986-06-03 DK DK260086A patent/DK154290C/en active
1987
- 1987-04-23 GB GB08709579A patent/GB2188932B/en not_active Expired
1988
- 1988-03-02 DK DK111188A patent/DK159389C/en active
- 1988-12-29 AU AU27614/88A patent/AU605007B2/en not_active Ceased
1989
- 1989-04-13 DK DK177489A patent/DK158989C/en active
1990
- 1990-01-19 DK DK015390A patent/DK158991C/en active
- 1990-01-19 DK DK015290A patent/DK158990C/en active
1992
- 1992-05-19 JP JP4150044A patent/JPH0635475B2/en not_active Expired - Lifetime
- 1992-05-19 JP JP4150045A patent/JPH0689022B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DK260086D0 (en)	1986-06-03
CH672920A5 (en)	1990-01-15
JPH0635475B2 (en)	1994-05-11
GB8709579D0 (en)	1987-05-28
DE3590488C2 (en)	1992-10-01
NL8520265A (en)	1986-09-01
IE58104B1 (en)	1993-06-30
BE903376A (en)	1986-02-03
IT1190401B (en)	1988-02-16
DK158990C (en)	1991-01-21
DK15290A (en)	1990-01-19
AU605007B2 (en)	1991-01-03
DK158991C (en)	1991-01-21
DK158989B (en)	1990-08-13
DK159389B (en)	1990-10-08
GB2167070A (en)	1986-05-21
DK177489A (en)	1989-04-13
JPS62500301A (en)	1987-02-05
WO1986002078A1 (en)	1986-04-10
DK154290B (en)	1988-10-31
FR2571369B1 (en)	1987-12-04
DK158990B (en)	1990-08-13
DK111188A (en)	1988-03-02
JPH0689022B2 (en)	1994-11-09
DE3590488T (en)	1986-10-09
AU4776185A (en)	1986-04-17
AU582789B2 (en)	1989-04-13
DK158991B (en)	1990-08-13
JPH0569103B2 (en)	1993-09-30
JPH05222089A (en)	1993-08-31
DK15390A (en)	1990-01-19
DK111188D0 (en)	1988-03-02
DK154290C (en)	1989-03-28
IT8522359A0 (en)	1985-10-04
GB2167070B (en)	1988-09-01
DK15390D0 (en)	1990-01-19
EP0197949A1 (en)	1986-10-22
GB8524479D0 (en)	1985-11-06
GB2188932B (en)	1988-09-01
DK159389C (en)	1991-03-11
DK260086A (en)	1986-06-03
DK158989C (en)	1991-01-21
IE852443L (en)	1986-04-04
DK177489D0 (en)	1989-04-13
JPH05178887A (en)	1993-07-20
DK15290D0 (en)	1990-01-19
GB2188932A (en)	1987-10-14
FR2571369A1 (en)	1986-04-11

Publication	Publication Date	Title
AU578840B2 (en)	1988-11-03	Substituted androsta-1, 4-diene-3,17-diones and process for their preparation
AU3256189A (en)	1989-08-03	Admixtures of steroids and drugs
AU551471B2 (en)	1986-05-01	9lamda-chloro-11beba-hydroxy-16beta-methyl-17lamda,21- dipropionyl-oxypregna-1,4-diene-3,20-dione
AU550264B2 (en)	1986-03-13	Plasma pyrolsis of waste
AU2902784A (en)	1984-12-13	X-ray dispersive structures and method of manufacture
AU1152588A (en)	1988-09-14	Fixing device and method for the manufacture of same
AU5234986A (en)	1986-07-01	Method and device for reducing the risk of disturbing noise from small children
AU6847894A (en)	1995-01-17	Method for the improvement of wound healing and compositions therefor
AU5040585A (en)	1986-06-12	Processes and apparatus for the smelting reduction of smeltable materials
AU8653091A (en)	1992-03-30	Crystallizing enamel composition and method of using the same
AU4787285A (en)	1986-04-10	Set delayed cement compositions and methods of using the same
AU3406893A (en)	1993-09-16	Method and composition for the treatment of osteoporosis
DE3567876D1 (en)	1989-03-02	Process and intermediates for the preparation of 17alpha-hydroxyprogesterones and corticoids from an enol steroid
AU7602781A (en)	1982-04-22	Compositions of anti-inflammatory steroids
AU584158B2 (en)	1989-05-18	New process for the preparation of certain steroids, especially intermediates for the preparation of proligestone and related compounds, and new intermediates formed in this process
AU7161187A (en)	1987-07-28	Aminoglycoside steroids
AU2761488A (en)	1989-06-08	Steroidal compounds and process for lengthening the side-chain of certain steroids
DE3565122D1 (en)	1988-10-27	Method for the determination of cholesterol
ZA884167B (en)	1989-03-29	Process for the preparation of 9(11)-dehydro steroids
AU3507495A (en)	1996-03-27	Process for the stereoselective reduction of steroid enelactams
AU587031B2 (en)	1989-08-03	11-B substituted steroids and process for their preparation
AU575783B2 (en)	1988-08-11	14-amino steroid derivatives
AU2369988A (en)	1989-04-20	Masking compositions for chemical milling and method for applying the same
AU5657494A (en)	1994-07-04	New steroids
DE3360856D1 (en)	1985-10-31	Pregnane derivatives and method of producing the same