[go: up one dir, main page]

DK1078001T3 - IL-6 antagonost peptider - Google Patents

IL-6 antagonost peptider

Info

Publication number
DK1078001T3
DK1078001T3 DK99926326T DK99926326T DK1078001T3 DK 1078001 T3 DK1078001 T3 DK 1078001T3 DK 99926326 T DK99926326 T DK 99926326T DK 99926326 T DK99926326 T DK 99926326T DK 1078001 T3 DK1078001 T3 DK 1078001T3
Authority
DK
Denmark
Prior art keywords
seq
present
antagonist peptides
peptide
peptides
Prior art date
Application number
DK99926326T
Other languages
Danish (da)
English (en)
Inventor
Ottaviano Serlupi-Crescenzi
Pietra Linda Della
Alessandro Bressan
Anna Rita Pezzotti
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of DK1078001T3 publication Critical patent/DK1078001T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99926326T 1998-05-18 1999-05-18 IL-6 antagonost peptider DK1078001T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98108997A EP0972780A1 (en) 1998-05-18 1998-05-18 Il-6 antagonist peptides
PCT/EP1999/003421 WO1999060013A2 (en) 1998-05-18 1999-05-18 Il-6 antagonist peptides

Publications (1)

Publication Number Publication Date
DK1078001T3 true DK1078001T3 (da) 2007-02-19

Family

ID=8231951

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99926326T DK1078001T3 (da) 1998-05-18 1999-05-18 IL-6 antagonost peptider

Country Status (14)

Country Link
US (2) US6599875B1 (sl)
EP (2) EP0972780A1 (sl)
JP (1) JP4468578B2 (sl)
AT (1) ATE347563T1 (sl)
AU (1) AU749616B2 (sl)
CA (2) CA2332817C (sl)
CY (1) CY1105865T1 (sl)
DE (1) DE69934308T2 (sl)
DK (1) DK1078001T3 (sl)
ES (1) ES2273492T3 (sl)
IL (2) IL139575A0 (sl)
PT (1) PT1078001E (sl)
SI (1) SI1078001T1 (sl)
WO (1) WO1999060013A2 (sl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0972780A1 (en) * 1998-05-18 2000-01-19 Applied Research Systems ARS Holding N.V. Il-6 antagonist peptides
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
ATE348163T1 (de) 1998-10-23 2007-01-15 Amgen Inc Thrombopoietin substitute
EP1773400A2 (en) 2004-07-08 2007-04-18 Amgen Inc. Therapeutic peptides
US20070036788A1 (en) * 2004-09-22 2007-02-15 Ahmed Sheriff Use of a compound for reducing the biological effectiveness of il-6
WO2006036834A2 (en) 2004-09-24 2006-04-06 Amgen Inc. MODIFIED Fc MOLECULES
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
JP5754875B2 (ja) 2006-04-07 2015-07-29 国立大学法人大阪大学 筋再生促進剤
US9283260B2 (en) 2006-04-21 2016-03-15 Amgen Inc. Lyophilized therapeutic peptibody formulations
KR101508019B1 (ko) 2007-01-23 2015-04-06 고쿠리츠 다이가쿠 호우징 신슈 다이가쿠 만성 거부반응 억제제
CN104906581A (zh) 2008-06-05 2015-09-16 国立研究开发法人国立癌症研究中心 神经浸润抑制剂
JP5898496B2 (ja) 2008-11-25 2016-04-06 アルダーバイオ ホールディングス エルエルシー Ｉｌ−６に対する抗体およびその使用
JP6051049B2 (ja) 2010-05-28 2016-12-21 中外製薬株式会社 抗腫瘍ｔ細胞応答増強剤
DK2643018T3 (da) 2010-11-23 2021-01-18 Vitaeris Inc Anti-il-6-antistoffer til behandling af oral mucositis
PL3636274T3 (pl) 2011-01-18 2025-01-20 Bioniz Therapeutics, Inc. Kompozycje do modulowania aktywności gamma-c-cytokiny
WO2013063229A1 (en) 2011-10-25 2013-05-02 The Regents Of The University Of Michigan Her2 targeting agent treatment in non-her2-amplified cancers having her2 expressing cancer stem cells
US9959384B2 (en) 2013-12-10 2018-05-01 Bioniz, Llc Methods of developing selective peptide antagonists
CN103923182A (zh) * 2014-01-17 2014-07-16 南通诚信氨基酸有限公司 白介素-6多肽抑制剂及其应用
US10030058B2 (en) 2015-10-09 2018-07-24 Bioniz, Llc Modulating gamma-C-cytokine activity
EP3620531A4 (en) 2017-05-02 2021-03-17 National Center of Neurology and Psychiatry METHOD OF PREDICTION AND EVALUATION OF THERAPEUTIC EFFECT IN DISEASES RELATING TO IL-6 AND NEUTROPHILS
WO2019078344A1 (ja) 2017-10-20 2019-04-25 学校法人兵庫医科大学 抗ｉｌ－６受容体抗体を含有する術後の癒着を抑制するための医薬組成物
WO2020201362A2 (en) 2019-04-02 2020-10-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of predicting and preventing cancer in patients having premalignant lesions
EP3976182A4 (en) 2019-05-03 2023-01-18 Bioniz, LLC MODULATION OF THE EFFECTS OF GAMMA CYTOKINE SIGNALING FOR THE TREATMENT OF ALOPECIA AND ALOPECIA-ASSOCIATED DISORDERS
CN116003530B (zh) * 2022-12-27 2023-12-15 西湖大学 一种针对白细胞介素-6的d-蛋白抑制剂及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4420782C1 (de) * 1994-06-15 1995-08-17 Fluegge Ulf Ingo Prof Dr DNA-Sequenz, kodierend einen 2-Oxoglutarat/Malat-Translokator, Plasmide, Bakterien, Hefen und Pflanzen enthaltend diesen Transporter
ATE217344T1 (de) * 1994-09-21 2002-05-15 Cytogen Corp Antigen bindende peptide (abtides) aus peptidbibliotheken
AU3204895A (en) * 1995-02-01 1996-08-21 University Of Massachusetts Medical Center Methods of selecting a random peptide that binds to a target protein
CA2220433C (en) * 1995-05-11 2010-02-16 Applied Research Systems Ars Holding N.V. Il-6 activity inhibitor
DE19628873A1 (de) * 1995-07-17 1997-01-23 Fraunhofer Ges Forschung Cyclitol
JP3913273B2 (ja) * 1995-09-28 2007-05-09 イエダ リサーチ アンド ディベロップメント カンパニー リミテッド Ｉｌ−６活性を阻害する合成ペプチド
AU3193097A (en) * 1996-06-20 1998-01-07 Koster, Henk W. Il-6 and il-6-receptor derived peptides having il-6 antagonistic or agonistic activity
EP0972780A1 (en) * 1998-05-18 2000-01-19 Applied Research Systems ARS Holding N.V. Il-6 antagonist peptides

Also Published As

Publication number Publication date
IL139575A (en) 2008-03-20
AU4362799A (en) 1999-12-06
EP1078001B1 (en) 2006-12-06
IL139575A0 (en) 2002-02-10
US6599875B1 (en) 2003-07-29
US6838433B2 (en) 2005-01-04
SI1078001T1 (sl) 2007-04-30
JP4468578B2 (ja) 2010-05-26
CY1105865T1 (el) 2011-02-02
PT1078001E (pt) 2007-01-31
WO1999060013A3 (en) 2000-03-09
US20030186876A1 (en) 2003-10-02
JP2002527354A (ja) 2002-08-27
CA2332817C (en) 2010-08-31
ATE347563T1 (de) 2006-12-15
EP1078001A2 (en) 2001-02-28
CA2332817A1 (en) 1999-11-25
DE69934308D1 (de) 2007-01-18
CA2690399C (en) 2015-01-20
DE69934308T2 (de) 2007-03-29
ES2273492T3 (es) 2007-05-01
EP0972780A1 (en) 2000-01-19
CA2690399A1 (en) 1999-11-25
AU749616B2 (en) 2002-06-27
WO1999060013A2 (en) 1999-11-25

Similar Documents

Publication Publication Date Title
DK1078001T3 (da) IL-6 antagonost peptider
BG98793A (bg) Нови производни на аминокиселините,методи за тяхното получаване и фармацевтични състави,съдържащи тези съединения
DK0894084T3 (da) Kanelsyrederivater og deres anvendelse som integrinantagonister
FI954609A0 (fi) 1-amidinofenyyli-pyrrolidoneja, -piperidinoneja ja -atsetinoneja verihiutaleiden kasaantumisen inhibiittoreina
IL123164A (en) Meta-guanidine urea thiourea or azacyclic amino benzoic acid derivatives and pharmaceutical compositions containing them
DK1086124T3 (da) Nye cyclosporiner
EP1093372A4 (en) CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND METHODS OF INHIBITING PEPTIDE RELEASE $ g (b) -AMYLOID AND / OR ITS SYNTHESIS USING THE SAME
IL104716A (en) 7-1-oxo-2- (substituted mercapto)-3- phenylpropyl) amino| octahydro-6-pyrido £2, 1-a| benzazepine- 4-carboxylic acid derivatives and analogs, their preparation and pharmaceutical compositions containing them for inhibiting enkephalinase and ace
TR200100889T2 (tr) Disfosfonik asit içeren terkipler
NO20000231L (no) Dolastatin-15-derivater
ES2120728T3 (es) Inhibidores de la agregacion de plaquetas.
ATE50693T1 (de) Peptidverbindungen.
DE69635996D1 (de) Pharmazeutische zusammensetzungen mit hydroximsäurederivaten
PT1079849E (pt) Utilizacao de proteinas hmg para a preparacao de medicamentos com actividade citotoxica
ES2110115T3 (es) Inhibidores de la agregacion de plaquetas.
DK1165544T3 (da) Substituerede 1,4-dihydroindeno[1,2-c]pyrazoler som inhibitorer af tyrosinkinase
ATE48001T1 (de) Cephemverbindungen, verfahren zu ihrer herstellung und ihre pharmazeutischen praeparate.
DK0804418T3 (da) Platelataggregationshæmmere
TNSN97092A1 (ar) مثبطات انزيم بروتيني فلزي وتركيبات صيدلانية تحتوي على تلك المثبتطات واستخدامها الصيدلاني وطرق ومركبات وسيطة مفيدة لتحضير التركيبات المذكورة.
HU9800970D0 (en) Process for producing pharmaceutical compositions containing heptapeptide somatostatin derivatives of neurogene- and non-neurogene-antiflogistic and analgesic activity and peptidomimetica
EA199900551A1 (ru) Фармацевтическая композиция, содержащая ингибитор иммуноглобулин-рецепторного взаимодействия
DE69433999D1 (de) Entzündungshemmende peptide
NO974537L (no) Plateaggregeringsinhibitorer inneholdende C-terminale aminergiske sidekjedeaminosyrerester
EP0817643A4 (en) SUBSTANCES AND COMPOSITIONS FOR THE ADMINISTRATION OF ACTIVE SUBSTANCES