DK0934278T3 - Bis(acridincarboxamid) og bis(phenazincarboxamid) som antitumormidler - Google Patents

Bis(acridincarboxamid) og bis(phenazincarboxamid) som antitumormidler

Info

Publication number: DK0934278T3
Authority: DK; Denmark
Prior art keywords: bis; carboxamide; pct; alkyl; different
Prior art date: 1996-10-18

Application number

DK97909456T

Other languages

Danish (da)

English (en)

Inventor

William Alexander Denny

Swarnalatha A Gamage

Julie Ann Spicer

Bruce Charles Baguley

Graeme John Finlay

Original Assignee

Xenova Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-18

Filing date

1997-10-17

Publication date

2003-01-06

1997-10-17 Application filed by Xenova Ltd filed Critical Xenova Ltd

2003-01-06 Application granted granted Critical

2003-01-06 Publication of DK0934278T3 publication Critical patent/DK0934278T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Multicomponent Fibers (AREA)
Polishing Bodies And Polishing Tools (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Liquid Crystal (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK97909456T 1996-10-18 1997-10-17 Bis(acridincarboxamid) og bis(phenazincarboxamid) som antitumormidler DK0934278T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9621795.5A GB9621795D0 (en)	1996-10-18	1996-10-18	Pharmaceutical compounds
PCT/GB1997/002886 WO1998017650A1 (en)	1996-10-18	1997-10-17	Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents

Publications (1)

Publication Number	Publication Date
DK0934278T3 true DK0934278T3 (da)	2003-01-06

Family

ID=10801674

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97909456T DK0934278T3 (da)	1996-10-18	1997-10-17	Bis(acridincarboxamid) og bis(phenazincarboxamid) som antitumormidler

Country Status (29)

Country	Link
US (1)	US6114332A (pt)
EP (1)	EP0934278B1 (pt)
JP (1)	JP2001503399A (pt)
KR (1)	KR20000049252A (pt)
CN (1)	CN1116285C (pt)
AT (1)	ATE223381T1 (pt)
AU (1)	AU717724B2 (pt)
BG (1)	BG64555B1 (pt)
BR (1)	BR9711948A (pt)
CA (1)	CA2268411C (pt)
CZ (1)	CZ295302B6 (pt)
DE (1)	DE69715230T2 (pt)
DK (1)	DK0934278T3 (pt)
ES (1)	ES2183142T3 (pt)
GB (2)	GB9621795D0 (pt)
HU (1)	HU221953B1 (pt)
ID (1)	ID22444A (pt)
MY (1)	MY122017A (pt)
NO (1)	NO313381B1 (pt)
NZ (1)	NZ335055A (pt)
PL (1)	PL193669B1 (pt)
PT (1)	PT934278E (pt)
RO (1)	RO120636B1 (pt)
RU (1)	RU2179972C2 (pt)
SK (1)	SK285121B6 (pt)
TW (1)	TW432060B (pt)
UA (1)	UA67729C2 (pt)
WO (1)	WO1998017650A1 (pt)
ZA (2)	ZA979328B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6974878B2 (en)	2001-03-21	2005-12-13	Symyx Technologies, Inc.	Catalyst ligands, catalytic metal complexes and processes using same
EP1131283A1 (en) *	1999-09-10	2001-09-12	Symyx Technologies	Catalyst ligands, catalytic metal complexes and processes using and methods of making same
AU2003300720A1 (en) *	2003-12-31	2005-07-21	Council Of Scientific And Industrial Research	C-8 linked pyrrolo(2,1-c)(1,4)benzodiazepine-acridone/acridine hybrids
WO2015100331A2 (en) *	2013-12-24	2015-07-02	University Of Florida Research Foundation, Inc.	Phenazine derivatives as antimicrobial agents
CN104961801B (zh) *	2015-07-13	2018-01-19	兰州大学	一种具有多靶点的抗菌多肽偶联物及其二聚物的合成和应用
CN106554321B (zh) *	2015-09-25	2019-05-28	陆源	一种吩嗪类物质、其制备方法及其应用
US20240279204A1 (en) *	2021-12-09	2024-08-22	Korea Institute Of Ocean Science & Technology	Novel diphenazine compound, and use thereof for preventing or treating cancer or neuroinflammatory diseases
WO2025043616A1 (zh) *	2023-08-31	2025-03-06	侯明宏	吖啶类衍生物用于抗癌的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ201084A (en) *	1982-06-25	1985-10-11	New Zealand Dev Finance	4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
EP0172744A2 (en) *	1984-08-16	1986-02-26	Development Finance Corporation Of New Zealand	Phenazinecarboxamide compounds
IT1293525B1 (it) *	1997-08-01	1999-03-01	Uni Degli Studi Camerino	Bis-acridincarbossiammidi aventi attivita' antitumorale

1996
- 1996-10-18 GB GBGB9621795.5A patent/GB9621795D0/en active Pending
1997
- 1997-10-17 NZ NZ335055A patent/NZ335055A/xx unknown
- 1997-10-17 PL PL97332877A patent/PL193669B1/pl not_active IP Right Cessation
- 1997-10-17 UA UA99042117A patent/UA67729C2/uk unknown
- 1997-10-17 RO RO99-00433A patent/RO120636B1/ro unknown
- 1997-10-17 JP JP51910998A patent/JP2001503399A/ja not_active Ceased
- 1997-10-17 AU AU47137/97A patent/AU717724B2/en not_active Ceased
- 1997-10-17 ES ES97909456T patent/ES2183142T3/es not_active Expired - Lifetime
- 1997-10-17 CZ CZ19991271A patent/CZ295302B6/cs not_active IP Right Cessation
- 1997-10-17 ID IDW990196A patent/ID22444A/id unknown
- 1997-10-17 BR BR9711948A patent/BR9711948A/pt not_active Application Discontinuation
- 1997-10-17 EP EP97909456A patent/EP0934278B1/en not_active Expired - Lifetime
- 1997-10-17 US US09/284,623 patent/US6114332A/en not_active Expired - Fee Related
- 1997-10-17 RU RU99109978/04A patent/RU2179972C2/ru not_active IP Right Cessation
- 1997-10-17 SK SK504-99A patent/SK285121B6/sk unknown
- 1997-10-17 PT PT97909456T patent/PT934278E/pt unknown
- 1997-10-17 ZA ZA979328A patent/ZA979328B/xx unknown
- 1997-10-17 DE DE69715230T patent/DE69715230T2/de not_active Expired - Fee Related
- 1997-10-17 HU HU9902883A patent/HU221953B1/hu not_active IP Right Cessation
- 1997-10-17 MY MYPI97004914A patent/MY122017A/en unknown
- 1997-10-17 ZA ZA9709331A patent/ZA979331B/xx unknown
- 1997-10-17 CN CN97180614A patent/CN1116285C/zh not_active Expired - Fee Related
- 1997-10-17 KR KR1019990703357A patent/KR20000049252A/ko not_active Ceased
- 1997-10-17 CA CA002268411A patent/CA2268411C/en not_active Expired - Fee Related
- 1997-10-17 GB GB9908192A patent/GB2334032B/en not_active Expired - Lifetime
- 1997-10-17 AT AT97909456T patent/ATE223381T1/de not_active IP Right Cessation
- 1997-10-17 WO PCT/GB1997/002886 patent/WO1998017650A1/en not_active Ceased
- 1997-10-17 DK DK97909456T patent/DK0934278T3/da active
- 1997-10-18 TW TW086115404A patent/TW432060B/zh not_active IP Right Cessation
1999
- 1999-04-13 BG BG103329A patent/BG64555B1/bg unknown
- 1999-04-16 NO NO19991833A patent/NO313381B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU221953B1 (hu)	2003-03-28
DE69715230D1 (de)	2002-10-10
CA2268411A1 (en)	1998-04-30
ZA979328B (en)	1998-07-06
BG103329A (en)	2000-11-30
UA67729C2 (uk)	2004-07-15
BG64555B1 (bg)	2005-07-29
AU4713797A (en)	1998-05-15
PL193669B1 (pl)	2007-03-30
GB2334032A (en)	1999-08-11
NO313381B1 (no)	2002-09-23
HUP9902883A3 (en)	2001-01-29
US6114332A (en)	2000-09-05
NZ335055A (en)	2000-09-29
CN1116285C (zh)	2003-07-30
JP2001503399A (ja)	2001-03-13
DE69715230T2 (de)	2009-09-17
CN1240430A (zh)	2000-01-05
NO991833L (no)	1999-06-03
ATE223381T1 (de)	2002-09-15
TW432060B (en)	2001-05-01
PT934278E (pt)	2003-01-31
ZA979331B (en)	1998-05-21
GB9621795D0 (en)	1996-12-11
NO991833D0 (no)	1999-04-16
ID22444A (id)	1999-10-14
HK1018773A1 (en)	2000-01-07
GB9908192D0 (en)	1999-06-02
CZ127199A3 (cs)	1999-09-15
CZ295302B6 (cs)	2005-07-13
ES2183142T3 (es)	2003-03-16
BR9711948A (pt)	1999-08-24
AU717724B2 (en)	2000-03-30
MY122017A (en)	2006-03-31
SK285121B6 (sk)	2006-06-01
EP0934278A1 (en)	1999-08-11
CA2268411C (en)	2008-07-22
EP0934278B1 (en)	2002-09-04
KR20000049252A (ko)	2000-07-25
PL332877A1 (en)	1999-10-25
RU2179972C2 (ru)	2002-02-27
GB2334032B (en)	2000-11-08
SK50499A3 (en)	2000-05-16
RO120636B1 (ro)	2006-05-30
WO1998017650A1 (en)	1998-04-30

Publication	Publication Date	Title
NZ239425A (en)	1993-10-26	Sulphonamide derivatives and pharmaceutical compositions
RU2000113595A (ru)	2004-02-20	Производные пиридонкарбоновой кислоты или его соль
MXPA02006329A (es)	2004-05-14	8-arilquinolinas sustituidas que son inhibidores de fosfodiesterasa-4.
DE50204780D1 (de)	2005-12-08	Arylsulfonamide als antivirale mittel
DK0934278T3 (da)	2003-01-06	Bis(acridincarboxamid) og bis(phenazincarboxamid) som antitumormidler
CA2045857A1 (en)	1992-01-11	Diaminotrifluoromethylpyridine Derivatives, Process for Their Production and Phospholipase A2 Inhibitor Containing Them
DK1086096T3 (da)	2003-11-10	Benzamider med tetrahydrofuranyloxy-substituenter som inhibitorer af phosphodiesterase 4
GR3029471T3 (en)	1999-05-28	2-substituted quinolines for treating leishmanioses.
MX9701949A (es)	1997-06-28	Derivados de distamicina substituidos con bis-(2-haloetil) aminofenilo como agentes antitumorales y antivirales.
ATE138364T1 (de)	1996-06-15	Hemmungsstoff für aldosereduktase
NO955197L (no)	1996-02-16	Nye carbosykliske nukleoside midler som er anvendbare som selektive inhibitorer av pro-inflammatoriske cytokiner
KR960702463A (ko)	1996-04-27	Dc-89 유도체[dc-89 derivative]
DE60221251D1 (de)	2007-08-30	Bis(2-aryl-5-pyridyl)derivate
PL366894A1 (en)	2005-02-07	Variolin derivatives and their use as antitumor agents
DE60221250D1 (de)	2007-08-30	Bis(5-aryl-2-pyridyl)derivate
CO4940468A1 (es)	2000-07-24	Nuevos derivados de naftilpiperacina
TH18165A (th)	1996-04-19	สารยับยั้งการเกิดคีโมแทกซิของอีโอซีโนฟีล