DK0987998T3 - Decellulering af væv - Google Patents
Decellulering af vævInfo
- Publication number
- DK0987998T3 DK0987998T3 DK98918067T DK98918067T DK0987998T3 DK 0987998 T3 DK0987998 T3 DK 0987998T3 DK 98918067 T DK98918067 T DK 98918067T DK 98918067 T DK98918067 T DK 98918067T DK 0987998 T3 DK0987998 T3 DK 0987998T3
- Authority
- DK
- Denmark
- Prior art keywords
- tissue
- decellulation
- acellular
- mineralization
- immunoreactivity
- Prior art date
Links
- 230000033558 biomineral tissue development Effects 0.000 abstract 1
- 210000003709 heart valve Anatomy 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 210000003041 ligament Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000002435 tendon Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2415—Manufacturing methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/915—Method or apparatus for preparing biological material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/915—Method or apparatus for preparing biological material
- Y10S623/916—Blood vessel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/915—Method or apparatus for preparing biological material
- Y10S623/918—Heart
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Steroid Compounds (AREA)
- Glass Compositions (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83885297A | 1997-04-11 | 1997-04-11 | |
| PCT/US1998/007072 WO1998046165A1 (en) | 1997-04-11 | 1998-04-10 | Tissue decellularization |
| EP98918067A EP0987998B1 (en) | 1997-04-11 | 1998-04-10 | Tissue decellularization |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0987998T3 true DK0987998T3 (da) | 2005-01-17 |
Family
ID=25278218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98918067T DK0987998T3 (da) | 1997-04-11 | 1998-04-10 | Decellulering af væv |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20010000804A1 (da) |
| EP (1) | EP0987998B1 (da) |
| JP (1) | JP2001520542A (da) |
| AT (1) | ATE279163T1 (da) |
| AU (1) | AU746318B2 (da) |
| CA (1) | CA2286655C (da) |
| DE (1) | DE69827001T2 (da) |
| DK (1) | DK0987998T3 (da) |
| ES (1) | ES2231980T3 (da) |
| PT (1) | PT987998E (da) |
| WO (1) | WO1998046165A1 (da) |
Families Citing this family (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1032435B1 (en) | 1997-10-31 | 2003-09-03 | Children's Medical Center Corporation | Bladder reconstruction |
| US6630001B2 (en) * | 1998-06-24 | 2003-10-07 | International Heart Institute Of Montana Foundation | Compliant dehyrated tissue for implantation and process of making the same |
| US6254564B1 (en) | 1998-09-10 | 2001-07-03 | Percardia, Inc. | Left ventricular conduit with blood vessel graft |
| US6214054B1 (en) * | 1998-09-21 | 2001-04-10 | Edwards Lifesciences Corporation | Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby |
| US6576265B1 (en) | 1999-12-22 | 2003-06-10 | Acell, Inc. | Tissue regenerative composition, method of making, and method of use thereof |
| US6479064B1 (en) * | 1999-12-29 | 2002-11-12 | Children's Medical Center Corporation | Culturing different cell populations on a decellularized natural biostructure for organ reconstruction |
| US6866686B2 (en) * | 2000-01-28 | 2005-03-15 | Cryolife, Inc. | Tissue graft |
| DE10010073B4 (de) | 2000-02-28 | 2005-12-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verankerung für implantierbare Herzklappenprothesen |
| DE10010074B4 (de) | 2000-02-28 | 2005-04-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vorrichtung zur Befestigung und Verankerung von Herzklappenprothesen |
| AU2001255741B2 (en) | 2000-04-28 | 2005-08-04 | Baylor College Of Medicine | Decellularized vascular prostheses |
| ATE332964T1 (de) | 2000-08-16 | 2006-08-15 | Univ Duke | Mittels gewebetechnologie hergestellte dezellularisierte gegenstände und gewebe |
| FR2828263B1 (fr) | 2001-08-03 | 2007-05-11 | Philipp Bonhoeffer | Dispositif d'implantation d'un implant et procede d'implantation du dispositif |
| US6878168B2 (en) | 2002-01-03 | 2005-04-12 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
| US8308797B2 (en) | 2002-01-04 | 2012-11-13 | Colibri Heart Valve, LLC | Percutaneously implantable replacement heart valve device and method of making same |
| US7402319B2 (en) | 2002-09-27 | 2008-07-22 | Board Of Regents, The University Of Texas System | Cell-free tissue replacement for tissue engineering |
| AU2003302898A1 (en) * | 2002-12-11 | 2004-06-30 | Cryolife, Inc. | Radical retardant cryopreservation solutions |
| US20040176855A1 (en) * | 2003-03-07 | 2004-09-09 | Acell, Inc. | Decellularized liver for repair of tissue and treatment of organ deficiency |
| EP1644011A1 (en) | 2003-06-25 | 2006-04-12 | Stephen F. Badylak | Conditioned matrix compositions for tissue restoration |
| DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
| US20100112543A1 (en) * | 2005-03-16 | 2010-05-06 | Manh-Dan Ngo | Processing soft tissue, methods and compositions related thereto |
| CA2602100A1 (en) * | 2005-03-16 | 2006-09-28 | Musculoskeletal Transplant Foundation | Soft tissue processing |
| EP2431063B1 (en) | 2005-08-26 | 2015-06-17 | Regents of the University of Minnesota | Decellularization and recellularization of organs and tissues |
| DE102005051849B4 (de) | 2005-10-28 | 2010-01-21 | JenaValve Technology Inc., Wilmington | Vorrichtung zur Implantation und Befestigung von Herzklappenprothesen |
| DE102005052628B4 (de) | 2005-11-04 | 2014-06-05 | Jenavalve Technology Inc. | Selbstexpandierendes, flexibles Drahtgeflecht mit integrierter Klappenprothese für den transvaskulären Herzklappenersatz und ein System mit einer solchen Vorrichtung und einem Einführkatheter |
| US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
| US20070162119A1 (en) * | 2006-01-07 | 2007-07-12 | Medical College Of Georgia Research Institute, Inc. | Tympanic membrane prosthesis and a tool for manufacturing the prosthesis |
| CN101626682B (zh) | 2006-10-27 | 2014-04-16 | 爱德华兹生命科学公司 | 用于外科植入的生物组织 |
| US9138315B2 (en) | 2007-04-13 | 2015-09-22 | Jenavalve Technology Gmbh | Medical device for treating a heart valve insufficiency or stenosis |
| US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
| CN101720211B (zh) | 2007-05-15 | 2013-06-05 | 耶拿阀门科技公司 | 用于操纵导管尖端的手柄、导管系统和用于插入自扩式心脏瓣膜支架的医疗插入系统 |
| JP2010528613A (ja) | 2007-05-29 | 2010-08-26 | クリストファー ビー． リード， | 多能細胞集団を産生する方法およびその使用 |
| KR101804287B1 (ko) | 2007-06-08 | 2017-12-04 | 웨이크 포리스트 유니버시티 헬스 사이언시즈 | 신부전 치료를 위한 선택적 세포 치료법 |
| US9580688B2 (en) | 2007-06-08 | 2017-02-28 | Wake Forest University Health Sciences | Kidney structures and methods of forming the same |
| US9101691B2 (en) * | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
| US8357387B2 (en) | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
| WO2011104269A1 (en) | 2008-02-26 | 2011-09-01 | Jenavalve Technology Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US8465540B2 (en) | 2008-02-26 | 2013-06-18 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis |
| US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
| US9168130B2 (en) | 2008-02-26 | 2015-10-27 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US8398704B2 (en) | 2008-02-26 | 2013-03-19 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US8317858B2 (en) | 2008-02-26 | 2012-11-27 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US9044305B2 (en) * | 2008-04-03 | 2015-06-02 | Cook Medical Technologies Llc | Self cleaning devices, systems and methods of use |
| EP2113261B1 (en) * | 2008-04-29 | 2013-11-06 | Proxy Biomedical Limited | A Tissue Repair Implant |
| AU2009293001B2 (en) * | 2008-09-18 | 2014-12-04 | The Curators Of The University Of Missouri | Bionanocomposite for tissue regeneration and soft tissue repair |
| WO2010057013A1 (en) | 2008-11-14 | 2010-05-20 | Wake Forest University Health Sciences | Selective cell therapy for the treatment of renal failure |
| US9150318B1 (en) | 2009-01-02 | 2015-10-06 | Lifecell Corporation | Method for sterilizing an acellular tissue matrix |
| EP2405742A2 (en) * | 2009-03-11 | 2012-01-18 | CryoLife, Inc. | Bioburden-reducing antibiotic composition and method of use |
| US20100292779A1 (en) | 2009-05-15 | 2010-11-18 | Helmut Straubinger | Device for compressing a stent and a system as well as a method for loading a stent into a medical delivery system |
| US8652500B2 (en) | 2009-07-22 | 2014-02-18 | Acell, Inc. | Particulate tissue graft with components of differing density and methods of making and using the same |
| US8298586B2 (en) | 2009-07-22 | 2012-10-30 | Acell Inc | Variable density tissue graft composition |
| FR2951549B1 (fr) | 2009-10-15 | 2013-08-23 | Olivier Schussler | Procede d'obtention de bioprotheses medicales implantables |
| US9566369B2 (en) | 2010-02-26 | 2017-02-14 | Decell Technologies Inc. | Methods for tissue decellularization |
| US8361144B2 (en) | 2010-03-01 | 2013-01-29 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve and methods associated therewith |
| EP2549957B1 (en) | 2010-03-23 | 2019-01-30 | Edwards Lifesciences Corporation | Methods of conditioning sheet bioprosthetic tissue |
| US11278406B2 (en) | 2010-05-20 | 2022-03-22 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect |
| US10856978B2 (en) | 2010-05-20 | 2020-12-08 | Jenavalve Technology, Inc. | Catheter system |
| BR112012029896A2 (pt) | 2010-05-25 | 2017-06-20 | Jenavalve Tech Inc | válcula cardíaca protética para endoprótese e endoprótese |
| US8906601B2 (en) | 2010-06-17 | 2014-12-09 | Edwardss Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
| EP2582411B1 (en) | 2010-06-17 | 2019-05-01 | Edwards Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
| JP5936610B2 (ja) | 2010-06-28 | 2016-06-22 | コリブリ ハート バルブ エルエルシーＣｏｌｉｂｒｉ Ｈｅａｒｔ Ｖａｌｖｅ Ｌｌｃ | 血管内注入装置の腔内搬送のための装置 |
| US8475827B2 (en) | 2010-07-06 | 2013-07-02 | Cryolife, Inc. | Tissue implants for implantation and methods for preparing the same |
| US8377143B2 (en) | 2010-07-06 | 2013-02-19 | Cryolife, Inc. | Tissue implants for implantation and methods for preparing the same |
| US8435305B2 (en) | 2010-08-31 | 2013-05-07 | Zimmer, Inc. | Osteochondral graft delivery device and uses thereof |
| ES2562707T3 (es) | 2010-09-01 | 2016-03-07 | Regents Of The University Of Minnesota | Métodos de recelularización de un tejido u órgano para una mejor capacidad de trasplante |
| US9351829B2 (en) | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
| SG10201601962WA (en) | 2010-12-14 | 2016-04-28 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets |
| AU2012262538B2 (en) * | 2011-05-27 | 2015-09-17 | Cormatrix Cardiovascular, Inc. | Sterilized, acellular extracellular matrix compositions and methods of making thereof |
| CA2852369A1 (en) | 2011-10-21 | 2013-04-25 | Jenavalve Technology Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect |
| CN102350008A (zh) | 2011-10-25 | 2012-02-15 | 微创医疗器械(上海)有限公司 | 一种处理动物源性胶原纤维材料的方法 |
| WO2013120082A1 (en) * | 2012-02-10 | 2013-08-15 | Kassab Ghassan S | Methods and uses of biological tissues for various stent and other medical applications |
| US9670457B2 (en) | 2012-05-08 | 2017-06-06 | Stem Cell Reserve Lp | Stem cells and matrix from cord tissue |
| US9878127B2 (en) | 2012-05-16 | 2018-01-30 | Jenavalve Technology, Inc. | Catheter delivery system for heart valve prosthesis |
| GB201215725D0 (en) | 2012-09-04 | 2012-10-17 | Univ Leeds | Composite connective tissue and bone implants |
| US10238771B2 (en) | 2012-11-08 | 2019-03-26 | Edwards Lifesciences Corporation | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system |
| EP2953580A2 (en) | 2013-02-11 | 2015-12-16 | Cook Medical Technologies LLC | Expandable support frame and medical device |
| CN105164250A (zh) | 2013-03-15 | 2015-12-16 | 米罗马特里克斯医疗公司 | 灌注脱细胞化的肝脏在胰岛细胞再细胞化中的用途 |
| US9795638B1 (en) * | 2013-03-16 | 2017-10-24 | BioDlogics, LLC | Cardiothoracic construct and methods of use |
| US9867694B2 (en) | 2013-08-30 | 2018-01-16 | Jenavalve Technology Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
| US9615922B2 (en) | 2013-09-30 | 2017-04-11 | Edwards Lifesciences Corporation | Method and apparatus for preparing a contoured biological tissue |
| US10959839B2 (en) | 2013-10-08 | 2021-03-30 | Edwards Lifesciences Corporation | Method for directing cellular migration patterns on a biological tissue |
| JP6524597B2 (ja) | 2013-11-04 | 2019-06-05 | ライフセル コーポレーションＬｉｆｅＣｅｌｌ Ｃｏｒｐｏｒａｔｉｏｎ | α−ガラクトースを除去する方法 |
| WO2015134618A1 (en) | 2014-03-04 | 2015-09-11 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Method and apparatus for decellularization of tissue |
| JP6829692B2 (ja) | 2015-03-20 | 2021-02-10 | イェーナヴァルヴ テクノロジー インコーポレイテッド | 心臓弁プロテーゼ送出システム及び導入体シースにより心臓弁プロテーゼを送出するための方法 |
| JP6767388B2 (ja) | 2015-05-01 | 2020-10-14 | イェーナヴァルヴ テクノロジー インコーポレイテッド | 心臓弁置換におけるペースメーカー割合を低減させるデバイス及び方法 |
| CN109475419B (zh) | 2016-05-13 | 2021-11-09 | 耶拿阀门科技股份有限公司 | 用于通过引导鞘和装载系统来递送心脏瓣膜假体的心脏瓣膜假体递送系统和方法 |
| WO2018048899A1 (en) | 2016-09-06 | 2018-03-15 | Micromatrix Medical Inc. | Use of resected liver serum for whole liver engineering |
| WO2018102826A1 (en) * | 2016-12-02 | 2018-06-07 | Vascudyne, Llc | Engineered tissue prosthesis |
| WO2018138658A1 (en) | 2017-01-27 | 2018-08-02 | Jenavalve Technology, Inc. | Heart valve mimicry |
| WO2018222434A1 (en) | 2017-05-31 | 2018-12-06 | Edwards Lifesciences Corporation | Collagen fibers and articles formed therefrom |
| WO2019051476A1 (en) | 2017-09-11 | 2019-03-14 | Incubar, LLC | SEALING DEVICE FOR USE AS A VASCULAR DUCT IMPLANT FOR REDUCING ENDOFUCTION |
| US12070530B2 (en) | 2017-11-09 | 2024-08-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Decellularization and functionalization of extracellular matrix biomaterials |
| AU2019212059A1 (en) | 2018-01-23 | 2020-05-21 | Edwards Lifesciences Corporation | Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby |
| US12263275B2 (en) | 2018-06-13 | 2025-04-01 | Miromatrix Medical Inc. | Fistula filler and deployment system |
| CN109260517B (zh) * | 2018-09-19 | 2020-10-30 | 杭州启明医疗器械股份有限公司 | 一种可预装干燥生物心脏瓣膜及其制备方法 |
| WO2020092205A1 (en) | 2018-11-01 | 2020-05-07 | Edwards Lifesciences Corporation | Transcatheter pulmonic regenerative valve |
| US12171658B2 (en) | 2022-11-09 | 2024-12-24 | Jenavalve Technology, Inc. | Catheter system for sequential deployment of an expandable implant |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8618374D0 (en) * | 1986-07-28 | 1986-09-03 | Hsc Res Dev Corp | Biological vascular prostheses |
| WO1995024873A1 (en) * | 1994-03-14 | 1995-09-21 | Cryolife, Inc. | Treated tissue for implantation and preparation methods |
| US5595571A (en) * | 1994-04-18 | 1997-01-21 | Hancock Jaffe Laboratories | Biological material pre-fixation treatment |
| AU5564996A (en) * | 1995-04-19 | 1996-11-07 | St. Jude Medical Inc. | Matrix substrate for a viable body tissue-derived prosthesis and method for making the same |
-
1998
- 1998-04-10 JP JP54403798A patent/JP2001520542A/ja active Pending
- 1998-04-10 EP EP98918067A patent/EP0987998B1/en not_active Expired - Lifetime
- 1998-04-10 DE DE69827001T patent/DE69827001T2/de not_active Expired - Lifetime
- 1998-04-10 CA CA002286655A patent/CA2286655C/en not_active Expired - Lifetime
- 1998-04-10 AT AT98918067T patent/ATE279163T1/de active
- 1998-04-10 DK DK98918067T patent/DK0987998T3/da active
- 1998-04-10 WO PCT/US1998/007072 patent/WO1998046165A1/en not_active Ceased
- 1998-04-10 ES ES98918067T patent/ES2231980T3/es not_active Expired - Lifetime
- 1998-04-10 AU AU71058/98A patent/AU746318B2/en not_active Ceased
- 1998-04-10 PT PT98918067T patent/PT987998E/pt unknown
-
2000
- 2000-12-14 US US09/735,522 patent/US20010000804A1/en not_active Abandoned
-
2003
- 2003-03-24 US US10/394,576 patent/US7318998B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2231980T3 (es) | 2005-05-16 |
| ATE279163T1 (de) | 2004-10-15 |
| US20030228692A1 (en) | 2003-12-11 |
| PT987998E (pt) | 2005-02-28 |
| WO1998046165A1 (en) | 1998-10-22 |
| JP2001520542A (ja) | 2001-10-30 |
| US7318998B2 (en) | 2008-01-15 |
| EP0987998A1 (en) | 2000-03-29 |
| AU746318B2 (en) | 2002-04-18 |
| AU7105898A (en) | 1998-11-11 |
| EP0987998B1 (en) | 2004-10-13 |
| CA2286655C (en) | 2009-02-24 |
| US20010000804A1 (en) | 2001-05-03 |
| DE69827001T2 (de) | 2005-09-08 |
| DE69827001D1 (de) | 2004-11-18 |
| EP0987998A4 (en) | 2002-05-22 |
| CA2286655A1 (en) | 1998-10-22 |
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