[go: up one dir, main page]

DK0869808T3 - Anvendelse af Glu-Trp-dipeptider til fremstilling af et lægemiddel til behandling af forskellige tilstande, der involverer neovaskularisation - Google Patents

Anvendelse af Glu-Trp-dipeptider til fremstilling af et lægemiddel til behandling af forskellige tilstande, der involverer neovaskularisation

Info

Publication number
DK0869808T3
DK0869808T3 DK96934021T DK96934021T DK0869808T3 DK 0869808 T3 DK0869808 T3 DK 0869808T3 DK 96934021 T DK96934021 T DK 96934021T DK 96934021 T DK96934021 T DK 96934021T DK 0869808 T3 DK0869808 T3 DK 0869808T3
Authority
DK
Denmark
Prior art keywords
glu
drug
preparation
treatment
various conditions
Prior art date
Application number
DK96934021T
Other languages
English (en)
Inventor
Lawrence R Green
John W Blasecki
Original Assignee
Cytran Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytran Ltd filed Critical Cytran Ltd
Application granted granted Critical
Publication of DK0869808T3 publication Critical patent/DK0869808T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
DK96934021T 1995-10-03 1996-10-02 Anvendelse af Glu-Trp-dipeptider til fremstilling af et lægemiddel til behandling af forskellige tilstande, der involverer neovaskularisation DK0869808T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53870195A 1995-10-03 1995-10-03
US08/614,764 US5902790A (en) 1995-10-03 1996-03-13 Pharmaceutical angiostatic dipeptide compositions and method of use thereof

Publications (1)

Publication Number Publication Date
DK0869808T3 true DK0869808T3 (da) 2006-11-13

Family

ID=27065900

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96934021T DK0869808T3 (da) 1995-10-03 1996-10-02 Anvendelse af Glu-Trp-dipeptider til fremstilling af et lægemiddel til behandling af forskellige tilstande, der involverer neovaskularisation

Country Status (23)

Country Link
US (4) US5902790A (da)
EP (1) EP0869808B1 (da)
JP (2) JP3679129B2 (da)
KR (1) KR100483779B1 (da)
CN (1) CN1128636C (da)
AT (1) ATE332702T1 (da)
AU (1) AU714846B2 (da)
BR (1) BR9610838A (da)
CA (1) CA2233457C (da)
CZ (1) CZ298345B6 (da)
DE (1) DE69636343T2 (da)
DK (1) DK0869808T3 (da)
EA (1) EA001146B1 (da)
ES (1) ES2268710T3 (da)
HU (1) HUP9902105A3 (da)
IL (1) IL123889A0 (da)
MX (1) MX9802564A (da)
NO (1) NO326298B1 (da)
NZ (1) NZ319907A (da)
PL (1) PL186123B1 (da)
SK (1) SK283677B6 (da)
TR (1) TR199800653T1 (da)
WO (1) WO1997012625A1 (da)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
US6060452A (en) * 1996-03-13 2000-05-09 Cytran, Inc. Analogs of L-Glu-L-Trp having pharmacological activity
AU3467099A (en) * 1998-04-03 1999-10-25 Cytran Ltd. Methods for production of therapeutic cytokines
PT1311269E (pt) 2000-08-04 2012-05-10 Dmi Biosciences Inc Método de utilização de dicetopiperazinas e composição que contém as mesmas
WO2002053170A2 (de) * 2001-01-02 2002-07-11 Institut Für Medizintechnologie Magdeburg Gmbh (Imtm) Kombinierte verwendung von enzyminhibitoren und pharmazeutischen zubereitungen daraus zur therapie und prophylaxe der arteriosklerose, zur therapie und prävention allergischer reaktionen von typ i nach gell und coombs und zur therapie und prävention dermatologischer erkrankungen mit follikulären und epidermalen hyperkeratos
DE10100052A1 (de) * 2001-01-02 2002-07-11 Inst Medizintechnologie Magdeb Kombinierte Verwendung von Enzyminhibitoren und pharmazeutischen Zubereitungen daraus zur Therapie und Prophylaxe der Atheriosklerose
US20030087830A1 (en) * 2001-06-12 2003-05-08 Eric Dupont Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof
RU2213571C2 (ru) * 2001-11-30 2003-10-10 Филиппова Ольга Всеволодовна Антигипоксическое средство
ATE520981T1 (de) 2002-10-02 2011-09-15 Dmi Biosciences Inc Diagnose und überwachung von krankheiten
CA3050734A1 (en) 2003-05-15 2004-12-02 Ampio Pharmaceuticals, Inc. Treatment of t-cell mediated diseases
WO2005016326A2 (en) * 2003-07-11 2005-02-24 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Analogs of thalidomide as potential angiogenesis inhibitors
CA2538864C (en) 2003-09-17 2013-05-07 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Thalidomide analogs as tnf-alpha modulators
US8952895B2 (en) 2011-06-03 2015-02-10 Apple Inc. Motion-based device operations
US20080233053A1 (en) * 2005-02-07 2008-09-25 Pharmalight Inc. Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
CA2569204A1 (en) * 2006-11-28 2008-05-28 Apotex Technologies Inc. Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan
CA2571645A1 (en) * 2006-12-19 2008-06-19 Apotex Technologies Inc. Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
EP2120986A4 (en) * 2007-02-13 2010-04-07 Sciclone Pharmaceuticals Inc METHOD FOR THE TREATMENT OR PREVENTION OF TISSUE WEAR, INJURY OR DAMAGE CAUSED BY SLEWER DISEASES
CA2579119C (en) 2007-02-16 2013-03-05 Apotex Technologies Inc. Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan
MX2010002046A (es) * 2007-08-23 2010-05-03 Sciclone Pharmaceuticals Inc Tratamiento de cancer de pulmon.
WO2009146320A1 (en) 2008-05-27 2009-12-03 Dmi Life Sciences, Inc. Therapeutic methods and compounds
DE102008032828A1 (de) * 2008-07-02 2010-01-07 Technische Universität Dresden Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel
CA2810844C (en) 2010-09-07 2017-03-21 Dmi Acquisition Corp. Diketopiperazine compositions for the treatment of metabolic syndrome and related conditions
JP6203734B2 (ja) 2011-10-10 2017-09-27 アンピオ ファーマシューティカルズ，インコーポレイテッド 変形性関節疾患の治療
PH12014500686A1 (en) 2011-10-10 2020-12-18 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
HK1198812A1 (en) 2011-10-28 2015-06-12 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
US8927725B2 (en) 2011-12-02 2015-01-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thio compounds
CN102631464B (zh) * 2012-05-18 2013-07-31 崔新明 一种治疗婴幼儿血管瘤的中药膏剂及其制备方法
MX2015010937A (es) 2013-03-15 2015-10-29 Ampio Pharmaceuticals Inc Composiciones para la movilizacion, autodireccion, expansion y diferenciacion de celulas madre y metodos para usar las mismas.
EP3183240A4 (en) 2014-08-18 2018-06-27 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9375478B1 (en) 2015-01-30 2016-06-28 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9687526B2 (en) 2015-01-30 2017-06-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9750785B2 (en) 2015-01-30 2017-09-05 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
HK1246669A1 (zh) 2015-06-22 2018-09-14 Ampio Pharmaceuticals, Inc. 人血清白蛋白低分子量组分在疾病治疗中的应用
US11266710B2 (en) 2017-08-31 2022-03-08 Singapore Health Services Pte Ltd. Angio-3 for treatment of retinal angiogenic diseases
CN116874557B (zh) * 2023-08-01 2024-12-20 首都医科大学 2-Trp-AA-四氢咔啉-3-羧酸类化合物及其PAF抑制剂的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997516A (en) * 1974-07-04 1976-12-14 Takeda Chemical Industries, Ltd. Method for protecting guanidino group and restoring the same
US4191753A (en) * 1978-11-06 1980-03-04 University Of Miami Anti-hypertensive peptide analogs
JP2511159B2 (ja) * 1987-12-30 1996-06-26 オブシェストボ エス オグラニチェンノイ オトベツベンノスチュ “ツィトメド―ペプトス” 免疫欠損状態の治療のための医薬製剤
US5728680A (en) * 1987-12-30 1998-03-17 Cytoven J.V. Methods for normalizing numbers of lymphocytes
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
SU1642398A1 (ru) * 1988-12-21 1991-04-15 Ростовский медицинский институт Способ лечени синуитов у детей
US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
US5770576A (en) * 1989-08-30 1998-06-23 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
RU1827255C (ru) * 1990-10-22 1993-07-15 Киевский государственный институт усовершенствования врачей Способ лечени туберкулеза легких
JP3068656B2 (ja) * 1991-03-07 2000-07-24 アピ株式会社 新規なペプチド及びアンジオテンシン変換酵素阻害ペプチド並びにそれらを含有する経口摂食組成物
CA2107460A1 (en) * 1991-04-01 1992-10-02 Vladimir K. Khavinson Pharmaceutical dipeptide compositions and methods of use thereof
RU2014063C1 (ru) * 1991-04-23 1994-06-15 Сочинский научно-исследовательский институт курортологии и физиотерапии Способ лечения подострых воспалительных заболеваний гениталий
DE69230500D1 (de) * 1991-10-28 2000-02-03 Cytran Ltd Pharmazeutische Dipeptid Zusammensetzungen und Verwendungsmethoden.
WO1995003067A1 (en) * 1993-07-21 1995-02-02 Khavinson Vladimir Khatskelevi Pharmaceutical with immunomodulating activity
CA2172494A1 (en) * 1993-09-24 1995-03-30 Kathleen Elizabeth Rodgers Use of angiotensin ii analogs in tissue repair

Also Published As

Publication number Publication date
KR19990063958A (ko) 1999-07-26
PL326149A1 (en) 1998-08-31
SK283677B6 (sk) 2003-11-04
MX9802564A (es) 1998-11-30
EP0869808B1 (en) 2006-07-12
US20060094665A1 (en) 2006-05-04
NO981436D0 (no) 1998-03-30
DE69636343D1 (de) 2006-08-24
BR9610838A (pt) 1999-12-21
KR100483779B1 (ko) 2007-03-02
IL123889A0 (en) 1998-10-30
US6096713A (en) 2000-08-01
JPH11504943A (ja) 1999-05-11
PL186123B1 (pl) 2003-10-31
HUP9902105A3 (en) 2001-02-28
NZ319907A (en) 2000-09-29
AU7254096A (en) 1997-04-28
EA199800357A1 (ru) 1998-10-29
ES2268710T3 (es) 2007-03-16
SK42398A3 (en) 1998-10-07
US5902790A (en) 1999-05-11
JP3679129B2 (ja) 2005-08-03
NO326298B1 (no) 2008-11-03
TR199800653T1 (xx) 1998-06-22
EA001146B1 (ru) 2000-10-30
EP0869808A1 (en) 1998-10-14
CA2233457A1 (en) 1997-04-10
US6911431B1 (en) 2005-06-28
ATE332702T1 (de) 2006-08-15
CN1128636C (zh) 2003-11-26
NO981436L (no) 1998-05-19
WO1997012625A1 (en) 1997-04-10
AU714846B2 (en) 2000-01-13
CZ298345B6 (cs) 2007-09-05
CN1198673A (zh) 1998-11-11
JP2005194287A (ja) 2005-07-21
DE69636343T2 (de) 2007-07-19
CZ91398A3 (cs) 1998-11-11
CA2233457C (en) 2004-08-03
HUP9902105A2 (hu) 1999-09-28

Similar Documents

Publication Publication Date Title
DK0869808T3 (da) Anvendelse af Glu-Trp-dipeptider til fremstilling af et lægemiddel til behandling af forskellige tilstande, der involverer neovaskularisation
DK1346041T3 (da) Terapeutiske midler og fremgangsmåder til anvendelse deraf til behandling af en amyloidogen sygdom
NO20013727L (no) Anvendelse av Botulinumtoksin B for fremstilling av et medikament
TR199801180T2 (xx) Aneljestik etkiye sahip yeni bile�ikler.
IS2537B (is) Lyfjablanda til inngjafar um húð
ATE424810T1 (de) Ein hydrokolloid und einen celluloseether enthaltende tablette mit verzögerter freisetzung
NO20053105D0 (no) Oral, analgesisk doseringsform med forlenget frigivelse for administrering ±n gang pr. dag.
ATE219363T1 (de) Lösliche prodrugs von paclitaxel
DK0932388T3 (da) Doseringsform og fremgangsmåde til indgivelse af lægemidler
ATE240344T1 (de) Nor-pregnane zur induzierung hypothalamischer effekte
PT921787E (pt) Regime de administracao de inibidores de atpase de h',k'
DK1039900T3 (da) Farmaceutisk præparat indeholdende sibutramin og orlistat
ATE319715T1 (de) Antikonvulsive pseudofructopyranose sulfamate
DE60026491D1 (de) Melagatran zur behandlung von entzündungen
IS1910B (is) Notkun á fankínóni til meðhöndlunar á Alzheimers-sjúkdómi
TR199801184T2 (xx) Analjezik tesirli yeni bile�ikler.
MXPA01012936A (es) Composicion farmaceutica que contiene sibutramina y orlistat.
ATE169922T1 (de) Desoxyazaphospholipid-derivate mit inhibierender aktivität auf phospholipase
DK0703781T3 (da) Anvendelse af Efaroxan og derivater deraf til fremstilling af et lægemiddel til behandling af Parkinsons sygdom
RU96104214A (ru) Способ лечения транссудативных форм центральных хориоретинальных дистрофий
FI930097A7 (fi) Annostusmuoto lääkeaineen antamiseksi vuorokausiterapian toteuttamista varten
SE9203296D0 (sv) The use of inositoltrisphate for the preparing of medicaments
RU96124465A (ru) Способ лечения стойких дезадаптационных психовегетативных расстройств