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DK0389282T3 - Xanthinderivater, fremgangsmåde til deres fremstilling og deres farmaceutiske anvendelse - Google Patents

Xanthinderivater, fremgangsmåde til deres fremstilling og deres farmaceutiske anvendelse

Info

Publication number
DK0389282T3
DK0389282T3 DK90303093T DK90303093T DK0389282T3 DK 0389282 T3 DK0389282 T3 DK 0389282T3 DK 90303093 T DK90303093 T DK 90303093T DK 90303093 T DK90303093 T DK 90303093T DK 0389282 T3 DK0389282 T3 DK 0389282T3
Authority
DK
Denmark
Prior art keywords
formula
disorders
processes
preparation
group
Prior art date
Application number
DK90303093T
Other languages
English (en)
Inventor
Harald Maschler
Barbara Ann Spicer
Harry Beecham Pharmaceut Smith
Original Assignee
Beecham Group Plc
Smithkline Beecham Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc, Smithkline Beecham Pharma Gmbh filed Critical Beecham Group Plc
Application granted granted Critical
Publication of DK0389282T3 publication Critical patent/DK0389282T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK90303093T 1989-03-23 1990-03-22 Xanthinderivater, fremgangsmåde til deres fremstilling og deres farmaceutiske anvendelse DK0389282T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898906792A GB8906792D0 (en) 1989-03-23 1989-03-23 Treatment and compounds

Publications (1)

Publication Number Publication Date
DK0389282T3 true DK0389282T3 (da) 2002-06-03

Family

ID=10653940

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90303093T DK0389282T3 (da) 1989-03-23 1990-03-22 Xanthinderivater, fremgangsmåde til deres fremstilling og deres farmaceutiske anvendelse

Country Status (27)

Country Link
US (4) US5981535A (da)
EP (2) EP1120417A3 (da)
JP (1) JP2510889B2 (da)
KR (1) KR0160768B1 (da)
CN (1) CN1031641C (da)
AT (1) ATE213498T1 (da)
AU (1) AU629315B2 (da)
CA (1) CA2012686C (da)
CZ (1) CZ391891A3 (da)
DE (1) DE69033915T2 (da)
DK (1) DK0389282T3 (da)
ES (1) ES2173074T3 (da)
FI (1) FI95033C (da)
GB (1) GB8906792D0 (da)
HK (1) HK1040392A1 (da)
HU (1) HU207081B (da)
IL (1) IL93832A (da)
MA (1) MA21800A1 (da)
MY (1) MY109737A (da)
NO (1) NO175592C (da)
NZ (1) NZ233021A (da)
PL (1) PL164811B1 (da)
PT (1) PT93527B (da)
SA (1) SA90100215B1 (da)
SK (1) SK391891A3 (da)
ZA (1) ZA902170B (da)
ZW (1) ZW3690A1 (da)

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US5981535A (en) 1999-11-09
GB8906792D0 (en) 1989-05-10
CN1031641C (zh) 1996-04-24
US6180791B1 (en) 2001-01-30
JP2510889B2 (ja) 1996-06-26
ZA902170B (en) 1991-03-27
PL164811B1 (pl) 1994-10-31
FI95033B (fi) 1995-08-31
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EP1120417A2 (en) 2001-08-01
IL93832A (en) 1994-07-31
NO901300D0 (no) 1990-03-21
KR0160768B1 (ko) 1998-12-01
CZ391891A3 (en) 1993-11-17
EP0389282A3 (en) 1992-07-01
ATE213498T1 (de) 2002-03-15
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CA2012686C (en) 1999-12-07
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PT93527B (pt) 1996-08-30
HU901792D0 (en) 1990-06-28
EP0389282A2 (en) 1990-09-26
DE69033915D1 (de) 2002-03-28
FI95033C (fi) 1995-12-11
HUT54155A (en) 1991-01-28
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PT93527A (pt) 1990-11-07
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CN1047502A (zh) 1990-12-05
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