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DE69303032D1 - Als süsstoffe brauchbare verbindungen und hir herstellungsverfahren - Google Patents

Als süsstoffe brauchbare verbindungen und hir herstellungsverfahren

Info

Publication number
DE69303032D1
DE69303032D1 DE69303032T DE69303032T DE69303032D1 DE 69303032 D1 DE69303032 D1 DE 69303032D1 DE 69303032 T DE69303032 T DE 69303032T DE 69303032 T DE69303032 T DE 69303032T DE 69303032 D1 DE69303032 D1 DE 69303032D1
Authority
DE
Germany
Prior art keywords
connectives
hir
sweetener
production method
hydroxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69303032T
Other languages
English (en)
Other versions
DE69303032T2 (de
Inventor
Claude Nofre
Jean-Marie Tinti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69303032D1 publication Critical patent/DE69303032D1/de
Publication of DE69303032T2 publication Critical patent/DE69303032T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
DE69303032T 1992-11-12 1993-11-10 Als süsstoffe brauchbare verbindungen und hir herstellungsverfahren Expired - Lifetime DE69303032T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9213615A FR2697844B1 (fr) 1992-11-12 1992-11-12 Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
PCT/FR1993/001103 WO1994011391A1 (fr) 1992-11-12 1993-11-10 Composes utiles comme agents edulcorants, leur procede de preparation

Publications (2)

Publication Number Publication Date
DE69303032D1 true DE69303032D1 (de) 1996-07-11
DE69303032T2 DE69303032T2 (de) 1996-10-02

Family

ID=9435473

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69303032T Expired - Lifetime DE69303032T2 (de) 1992-11-12 1993-11-10 Als süsstoffe brauchbare verbindungen und hir herstellungsverfahren

Country Status (32)

Country Link
US (1) US5480668A (de)
EP (1) EP0669935B1 (de)
JP (1) JP2818032B2 (de)
KR (1) KR100254297B1 (de)
CN (1) CN1038747C (de)
AT (1) ATE138935T1 (de)
AU (1) AU664663B2 (de)
BG (1) BG61609B1 (de)
CA (1) CA2139233C (de)
CZ (1) CZ285018B6 (de)
DE (1) DE69303032T2 (de)
DK (1) DK0669935T3 (de)
EC (1) ECSP930999A (de)
EE (1) EE03194B1 (de)
ES (1) ES2091114T3 (de)
FI (1) FI114314B (de)
FR (1) FR2697844B1 (de)
GR (1) GR3020164T3 (de)
HU (1) HU218158B (de)
IL (1) IL107551A (de)
LT (1) LT3142B (de)
MD (1) MD1450G2 (de)
NO (1) NO309862B1 (de)
NZ (1) NZ257870A (de)
PL (1) PL177090B1 (de)
RO (1) RO112621B1 (de)
RU (1) RU2107071C1 (de)
SK (1) SK280180B6 (de)
TW (1) TW260673B (de)
UA (1) UA39869C2 (de)
WO (1) WO1994011391A1 (de)
ZA (1) ZA938430B (de)

Families Citing this family (136)

* Cited by examiner, † Cited by third party
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FR2719590B1 (fr) * 1994-05-09 1996-07-26 Claude Nofre Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
JPH09323966A (ja) 1996-01-12 1997-12-16 Ajinomoto Co Inc 新規アスパルチルアミド誘導体及び甘味剤
FR2744454B1 (fr) * 1996-02-07 1998-04-24 Nofre Claude Acide n-(3,3-dimethylbutyl)-l-aspartyl-d-alpha- aminoalcanoique n-(s)-1-phenyl-1-alcanamide utile comme agent edulcorant
US5728862A (en) * 1997-01-29 1998-03-17 The Nutrasweet Company Method for preparing and purifying an N-alkylated aspartame derivative
US5770775A (en) * 1997-02-10 1998-06-23 The Nutrasweet Company Method for preparing 3,3-dimethylbutyraldehyde
DE69739895D1 (de) * 1997-03-10 2010-07-08 Ajinomoto Kk Süßstoffzusammensetzung mit verbessertem Geschmack, ihre Verwendung und Herstellungsverfahren
JPH10259194A (ja) * 1997-03-18 1998-09-29 Ajinomoto Co Inc 新規ジペプチド誘導体及び甘味剤
US5973209A (en) * 1997-07-11 1999-10-26 The Nutrasweet Company Method for preparing 3, 3-dimethybutyraldehyde
US6146680A (en) * 1997-09-11 2000-11-14 The Nutrasweet Company Metal complexes of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US6129942A (en) * 1997-09-11 2000-10-10 The Nutrasweet Company Sweetener salts of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US6180156B1 (en) * 1997-09-11 2001-01-30 The Nutrasweet Company Acid salts of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US6291004B1 (en) * 1997-09-11 2001-09-18 The Nutrasweet Company Basic salts of n-[n-(3,3-dimethylbutyl)-l-α-aspartyl]-l-phenylalanine 1-methyl ester
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JPH11130794A (ja) * 1997-10-23 1999-05-18 Ajinomoto Co Inc アスパルテーム誘導体の精製方法
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JPH11169133A (ja) 1997-12-15 1999-06-29 Ajinomoto Co Inc アスパルテーム及びアスパルテーム誘導体を含有する甘味料組成物
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AR014129A1 (es) * 1997-12-17 2001-02-07 Nutrasweet Co Bebida que comprende fundamentalmente un ester n-[n-(3,3-dimetilbutil)-l- alfa-aspartil]-l-fenilamina 1 - metilico, bebida sin alcohol carbonatada,bebida de jugo, bebida envasada caliente y bebida deportiva de bajas calorias.
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JP3643921B2 (ja) * 1998-05-08 2005-04-27 味の素株式会社 新規甘味料組成物
JP3643922B2 (ja) * 1998-05-08 2005-04-27 味の素株式会社 甘味料組成物
US5905175A (en) * 1998-05-20 1999-05-18 The Nutrasweet Company Synthesis and purification of 3,3-dimethylbutyraldehyde via oxidation of 1-chloro-3,3-dimethylbutane with dimethyl sulfoxide
US6692778B2 (en) 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
WO1999062354A1 (en) * 1998-06-05 1999-12-09 Wm. Wrigley Jr. Company Method of controlling release of n-substituted derivatives of aspartame in chewing gum and gum produced thereby
AU2003213469B2 (en) * 1998-06-05 2005-12-22 Wm. Wrigley Jr. Company Method of Controlling Release of N-substituted Derivatives of Aspartame in Chewing Gum and Gum Produced Thereby
RU2225139C2 (ru) * 1998-06-05 2004-03-10 Вм. Ригли Дж. Компани Способ получения жевательной резинки, содержащей n-замещенное производное аспартама (варианты), и жевательная резинка, полученная по этому способу (варианты)
AU2006203624B2 (en) * 1998-06-05 2008-07-10 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum and gum produced thereby
CN1192036C (zh) * 1998-06-26 2005-03-09 味之素株式会社 天冬氨酰二肽酯衍生物以及甜味剂
US5977415A (en) * 1998-08-20 1999-11-02 The Nutrasweet Company Preparation of 3, 3-dimethylbutyraldehyde from a tert-butyl cation precursor, vinyl chloride and an acidic catalyst
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US5994593A (en) * 1998-09-17 1999-11-30 The Nutrasweet Company Synthesis and purification of 3,3-dimethylbutyraldehyde via hydrolysis of 1,1-dichloro-3,3-dimethylbutane or 1-bromo-1-chloro-3,3-dimethylbutane
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NO945090L (no) 1994-12-30
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MD960256A (en) 1998-03-31
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ECSP930999A (es) 1994-09-16
AU5468194A (en) 1994-06-08
LTIP1457A (en) 1994-06-15
CA2139233A1 (fr) 1994-05-26
MD1450G2 (ro) 2001-07-31
DE69303032T2 (de) 1996-10-02
CZ285018B6 (cs) 1999-05-12
CZ331994A3 (en) 1995-10-18
DK0669935T3 (da) 1996-07-01
HU9403842D0 (en) 1995-02-28
SK158694A3 (en) 1995-05-10
US5480668A (en) 1996-01-02
NO309862B1 (no) 2001-04-09
FI945451L (fi) 1994-12-22
BG99299A (bg) 1995-09-29
AU664663B2 (en) 1995-11-23
FR2697844A1 (fr) 1994-05-13
RU94046457A (ru) 1996-09-27
CA2139233C (fr) 2003-09-16
CN1038747C (zh) 1998-06-17
ATE138935T1 (de) 1996-06-15
MD1450F2 (en) 2000-04-30
JPH08503206A (ja) 1996-04-09
PL177090B1 (pl) 1999-09-30
TW260673B (de) 1995-10-21
FR2697844B1 (fr) 1995-01-27
RU2107071C1 (ru) 1998-03-20
JP2818032B2 (ja) 1998-10-30
IL107551A0 (en) 1994-02-27
NO945090D0 (no) 1994-12-30
ES2091114T3 (es) 1996-10-16
CN1090571A (zh) 1994-08-10
EP0669935A1 (de) 1995-09-06
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HU218158B (hu) 2000-06-28
KR100254297B1 (ko) 2000-05-01
FI114314B (fi) 2004-09-30
WO1994011391A1 (fr) 1994-05-26
PL306841A1 (en) 1995-04-18
EP0669935B1 (de) 1996-06-05
IL107551A (en) 1998-08-16
LT3142B (en) 1995-01-31
UA39869C2 (uk) 2001-07-16
RO112621B1 (ro) 1997-11-28
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SK280180B6 (sk) 1999-09-10
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