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DE69224124D1 - Verfahren zur Herstellung von Dihomo-Gamma-Linolensäure und das in dieser enthaltende Lipid - Google Patents

Verfahren zur Herstellung von Dihomo-Gamma-Linolensäure und das in dieser enthaltende Lipid

Info

Publication number
DE69224124D1
DE69224124D1 DE69224124T DE69224124T DE69224124D1 DE 69224124 D1 DE69224124 D1 DE 69224124D1 DE 69224124 T DE69224124 T DE 69224124T DE 69224124 T DE69224124 T DE 69224124T DE 69224124 D1 DE69224124 D1 DE 69224124D1
Authority
DE
Germany
Prior art keywords
dihomo
linolenic acid
gamma
preparation
lipid contained
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69224124T
Other languages
English (en)
Other versions
DE69224124T2 (de
Inventor
Hiroshi Kawashima
Kengo Akimoto
Hideaki Yamada
Sakayu Shimizu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Holdings Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Publication of DE69224124D1 publication Critical patent/DE69224124D1/de
Application granted granted Critical
Publication of DE69224124T2 publication Critical patent/DE69224124T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
DE69224124T 1991-09-30 1992-09-30 Verfahren zur Herstellung von Dihomo-Gamma-Linolensäure und das in dieser enthaltende Lipid Expired - Lifetime DE69224124T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP25196491A JP3354581B2 (ja) 1991-09-30 1991-09-30 ジホモ−γ−リノレン酸及びこれを含有する脂質の製造方法

Publications (2)

Publication Number Publication Date
DE69224124D1 true DE69224124D1 (de) 1998-02-26
DE69224124T2 DE69224124T2 (de) 1998-05-07

Family

ID=17230612

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69224124T Expired - Lifetime DE69224124T2 (de) 1991-09-30 1992-09-30 Verfahren zur Herstellung von Dihomo-Gamma-Linolensäure und das in dieser enthaltende Lipid

Country Status (9)

Country Link
US (2) US6280982B1 (de)
EP (1) EP0535940B1 (de)
JP (1) JP3354581B2 (de)
AT (1) ATE162551T1 (de)
CA (1) CA2079364C (de)
DE (1) DE69224124T2 (de)
DK (1) DK0535940T3 (de)
ES (1) ES2111052T3 (de)
HK (1) HK1007052A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3792309B2 (ja) 1996-08-30 2006-07-05 サントリー株式会社 不飽和脂肪酸含有油脂の製造方法
DK0960943T3 (en) 1996-12-27 2014-02-24 Suntory Holdings Ltd MEDIA FOR CULTIVATION OF MICRO-ORGANISMS AND METHOD FOR PRODUCING unsaturated fatty acids or lipids containing DEM
EP2175031A3 (de) 1997-03-04 2010-07-07 Suntory Holdings Limited Verfahren zur Herstellung hoch ungesättigter Fettsäuren und Fette mit hoch ungesättigten Fettsäuren
JP2000069987A (ja) 1998-08-28 2000-03-07 Suntory Ltd アラキドン酸含有脂質並びにジホモ−γ−リノレン酸含有脂質の製造方法
JP4748907B2 (ja) 1999-08-13 2011-08-17 サントリーホールディングス株式会社 脂質を菌体外に分泌する微生物ならびに当該微生物を用いた脂質および脂質を内包する油滴小胞の製造方法
JP4088097B2 (ja) 2002-04-26 2008-05-21 サントリー株式会社 高度不飽和脂肪酸含有脂質の製造方法
CA2501880C (en) 2002-10-11 2012-12-18 Suntory Limited Process for producing microbial fat or oil having lowered unsaponifiable matter content and said fat or oil
US8609397B2 (en) 2004-08-12 2013-12-17 Nippon Suisan Kaisha, Ltd. Method for preserving a microorganism
JPWO2006022356A1 (ja) * 2004-08-24 2008-05-08 サントリー株式会社 ジアシルグリセロールの含量を任意に含んだ微生物油脂の製造法並びに該油脂
JP4624040B2 (ja) 2004-09-06 2011-02-02 日本水産株式会社 菌体培養方法
JP4849806B2 (ja) 2005-02-08 2012-01-11 日本水産株式会社 新規な菌体処理方法を用いた高度不飽和脂肪酸の製造方法
CA2599112C (en) 2005-02-14 2013-10-22 Suntory Limited Composition comprising dihomo-.gamma.-linolenic acid (dgla) as the active ingredient
US8871808B2 (en) 2006-06-22 2014-10-28 Ben-Gurion University Of The Negev Research And Development Authority Et Al. Over-production of dihomo linolenic acid by a mutant strain of Parietochloris incisa
JP5101894B2 (ja) 2007-01-15 2012-12-19 サントリーホールディングス株式会社 高度不飽和脂肪酸及びこれを含有する脂質の製造方法
EP2179046B1 (de) * 2007-08-13 2013-01-02 Ben-Gurion University of the Negev Research and Development Authority Überproduktion von dihomo-gamma-linolensäure durch einen parietochloris incisa-mutantenstamm
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
EP2580229A4 (de) * 2010-06-10 2013-12-25 Univ Ben Gurion D5-desaturase-defektives mutantengen und verwendung davon
EP4461359B1 (de) 2011-05-12 2026-02-11 Nissui Corporation Zusammensetzung zur äusserlichen anwendung auf der haut für entzündliche erkrankungen
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
EP3077489B1 (de) * 2013-12-04 2021-05-12 Nippon Suisan Kaisha, Ltd. Dihomo-gamma-linolensäure-haltiges mikrobielles öl und dihomo-gamma-linolensäure-haltige mikrobielle biomasse
EP3151825B1 (de) 2014-06-04 2020-03-25 DS Biopharma Limited Pharmazeutische zusammensetzungen enthaltend dgla und verwendung derselben
EP3200606B1 (de) 2014-10-02 2021-03-31 Evonik Operations GmbH Verfahren zur herstellung eines pufas enthaltenden futtermittels durch extrusion einer pufas enthaltenden biomasse des typs labyrinthulomycetes
CA2958439C (en) 2014-10-02 2022-09-20 Evonik Industries Ag Feedstuff of high abrasion resistance and good stability in water, containing pufas
US11324234B2 (en) 2014-10-02 2022-05-10 Evonik Operations Gmbh Method for raising animals
CN118813731A (zh) 2014-10-02 2024-10-22 赢创运营有限公司 用于制备具有高细胞稳定性的含pufa生物质的方法
JP7599951B2 (ja) 2018-12-28 2024-12-16 株式会社ニッスイ アラキドン酸含量が低減されたジホモ－γ－リノレン酸含有微生物油
EP4039326A4 (de) 2019-10-01 2023-08-02 Suntory Holdings Limited Zusammensetzung zur verbesserung der darmfunktion durch expressionskontrolle von aquaporin 3 und ihre verwendung
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases
JPWO2024106446A1 (de) 2022-11-15 2024-05-23

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0722513B2 (ja) 1986-07-08 1995-03-15 サントリー株式会社 ビスホモ―γ―リノレン酸及びこれを含有する脂質の製造方法
EP0273708B1 (de) 1986-12-26 1994-03-23 Sagami Chemical Research Center Verfahren zur Herstellung von Eicosapentaensäure
JPS6447385A (en) 1987-08-19 1989-02-21 Idemitsu Petrochemical Co Production of lipid containing bis-homo-gamma-linolenic acid and/or arachidonic acid
US5034321A (en) 1987-08-19 1991-07-23 Idemitsu Petrochemical Co., Ltd. Method for the production of lipids containing bis-homo-γ-linolenic acid
JPS6447384A (en) 1987-08-19 1989-02-21 Idemitsu Petrochemical Co Production of lipid containing bis-homo-gamma-linolenic acid and/or arachidonic acid
JP2746371B2 (ja) * 1987-12-21 1998-05-06 サントリー株式会社 ビスホモ−γ−リノレン酸及びこれを含有する脂質の製造方法
JPH01228486A (ja) 1988-03-09 1989-09-12 Suntory Ltd 奇数鎖高度不飽和脂肪酸及びこれを含有する脂質の製造方法
JPH02268690A (ja) 1989-04-10 1990-11-02 Idemitsu Petrochem Co Ltd ビスホモ―γ―リノレン酸含有脂質の製造法
JP2958361B2 (ja) 1989-05-24 1999-10-06 出光石油化学株式会社 ジホモ―γ―リノレン酸の製造法および脂肪酸の△５位不飽和化反応抑制剤
JP2740854B2 (ja) 1989-07-18 1998-04-15 出光石油化学株式会社 ジホモ―γ―リノレン酸の製造法および脂肪酸の△５位不飽和化反応抑制剤
US5093249A (en) * 1989-05-24 1992-03-03 Idemitsu Petrochemical Co., Ltd. Process for production of dihomo-γ-linolenic acid and inhibitor for unsaturation reaction at Δ5-position of fatty acid
CN1168104A (zh) * 1995-01-18 1997-12-17 大正制药株式会社 皮肤炎治疗剂
US6107334A (en) * 1998-02-23 2000-08-22 Wake Forest University Dietary control of arachidonic acid metabolism

Also Published As

Publication number Publication date
DK0535940T3 (da) 1998-04-27
CA2079364C (en) 2003-04-08
US20010021522A1 (en) 2001-09-13
JP3354581B2 (ja) 2002-12-09
ES2111052T3 (es) 1998-03-01
EP0535940A1 (de) 1993-04-07
JPH0591887A (ja) 1993-04-16
US6280982B1 (en) 2001-08-28
ATE162551T1 (de) 1998-02-15
EP0535940B1 (de) 1998-01-21
US6602690B2 (en) 2003-08-05
CA2079364A1 (en) 1993-03-31
HK1007052A1 (en) 1999-03-26
DE69224124T2 (de) 1998-05-07

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Owner name: SUNTORY HOLDINGS LTD., OSAKA, JP

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