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DE69018514D1 - Substituierte Aminoalkylphosphinsäure. - Google Patents

Substituierte Aminoalkylphosphinsäure.

Info

Publication number
DE69018514D1
DE69018514D1 DE69018514T DE69018514T DE69018514D1 DE 69018514 D1 DE69018514 D1 DE 69018514D1 DE 69018514 T DE69018514 T DE 69018514T DE 69018514 T DE69018514 T DE 69018514T DE 69018514 D1 DE69018514 D1 DE 69018514D1
Authority
DE
Germany
Prior art keywords
denotes
hydrogen
halogen
hydroxy
methyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69018514T
Other languages
English (en)
Other versions
DE69018514T2 (de
Inventor
Roger Graham Dr Hall
Ludwig Dr Maier
Wolfgang Dr Froestl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE69018514D1 publication Critical patent/DE69018514D1/de
Application granted granted Critical
Publication of DE69018514T2 publication Critical patent/DE69018514T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/36—Amides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Luminescent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
DE69018514T 1989-05-13 1990-05-08 Substituierte Aminoalkylphosphinsäure. Expired - Fee Related DE69018514T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898911017A GB8911017D0 (en) 1989-05-13 1989-05-13 Substituted aminoalkylphosphinic acids

Publications (2)

Publication Number Publication Date
DE69018514D1 true DE69018514D1 (de) 1995-05-18
DE69018514T2 DE69018514T2 (de) 1995-09-21

Family

ID=10656689

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69018514T Expired - Fee Related DE69018514T2 (de) 1989-05-13 1990-05-08 Substituierte Aminoalkylphosphinsäure.

Country Status (24)

Country Link
EP (1) EP0399949B1 (de)
JP (1) JP2930366B2 (de)
KR (1) KR0159501B1 (de)
AT (1) ATE121095T1 (de)
AU (1) AU629335B2 (de)
CA (1) CA2016631C (de)
DD (1) DD294265A5 (de)
DE (1) DE69018514T2 (de)
DK (1) DK0399949T3 (de)
ES (1) ES2070303T3 (de)
FI (1) FI94416C (de)
GB (1) GB8911017D0 (de)
GR (1) GR3015770T3 (de)
HR (1) HRP940178A2 (de)
HU (1) HU206885B (de)
IE (1) IE66165B1 (de)
IL (1) IL94317A (de)
MX (1) MX20639A (de)
NO (1) NO176761C (de)
NZ (1) NZ233647A (de)
PT (1) PT94014B (de)
SI (1) SI9010917B (de)
YU (1) YU91790A (de)
ZA (1) ZA903611B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0543780A3 (en) * 1991-11-21 1993-09-01 Ciba-Geigy Ag Novel aminoalkanephosphinic acids and their salts
ES2200184T7 (es) 1996-07-24 2015-02-10 Warner-Lambert Company Llc Isobutilgaba y sus derivados para el tratamiento del dolor
WO2000004031A1 (de) 1998-07-15 2000-01-27 Hassan Jomaa Phosphororganische verbindungen und ihre verwendung
GB9906882D0 (en) * 1999-03-25 1999-05-19 Novartis Ag Organic compounds
SE9904508D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
US7319095B2 (en) 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
SE9904507D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
SE0102055D0 (sv) * 2001-06-08 2001-06-08 Astrazeneca Ab New Compounds
AR033779A1 (es) 2001-06-08 2004-01-07 Astrazeneca Ab Compuestos utiles en la enfermedad de reflujo
DK1691811T3 (da) 2003-12-11 2014-10-20 Sunovion Pharmaceuticals Inc Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
WO2007073298A1 (en) 2005-12-23 2007-06-28 Astrazeneca Ab Imidazole derivatives for the treatment of gastrointestinal disorders
JP2009521430A (ja) 2005-12-23 2009-06-04 アストラゼネカ・アクチエボラーグ Ｇａｂａ−ｂ受容体モジュレーター
DE102008056228A1 (de) * 2008-11-06 2010-05-12 Clariant International Limited Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, deren Salze und Ester und ihre Verwendung
DE102008056339A1 (de) * 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
WO2011113904A1 (en) 2010-03-17 2011-09-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration
WO2012050907A2 (en) 2010-09-28 2012-04-19 The Regents Of The University Of California Gaba agonists in the treatment of disorders associated with metabolic syndrome and gaba combinations in treatment or prophylaxis of type i diabetes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3311475C1 (de) * 1983-03-29 1984-08-16 Siemens AG, 1000 Berlin und 8000 München Mikroprogramm-Steuereinrichtung
DE3312165A1 (de) * 1983-04-02 1984-10-04 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von phosphinothricin
GB8728483D0 (en) * 1987-12-04 1988-01-13 Ciba Geigy Ag Chemical compounds
GB8820266D0 (en) * 1988-08-26 1988-09-28 Smith Kline French Lab Compounds

Also Published As

Publication number Publication date
GR3015770T3 (en) 1995-07-31
DD294265A5 (de) 1991-09-26
YU91790A (sh) 1992-07-20
FI902368A0 (fi) 1990-05-11
KR900018124A (ko) 1990-12-20
HRP940178A2 (en) 1996-08-31
AU629335B2 (en) 1992-10-01
CA2016631A1 (en) 1990-11-13
JPH0395195A (ja) 1991-04-19
CA2016631C (en) 2000-08-29
PT94014B (pt) 1996-12-31
NO176761C (no) 1995-05-24
HU206885B (en) 1993-01-28
HU903012D0 (en) 1990-09-28
FI94416B (fi) 1995-05-31
EP0399949A1 (de) 1990-11-28
ZA903611B (en) 1991-02-27
EP0399949B1 (de) 1995-04-12
PT94014A (pt) 1991-01-08
KR0159501B1 (ko) 1999-01-15
IL94317A0 (en) 1991-03-10
AU5480990A (en) 1990-11-15
NO902109D0 (no) 1990-05-11
NO176761B (no) 1995-02-13
DK0399949T3 (da) 1995-07-03
HUT53656A (en) 1990-11-28
IE66165B1 (en) 1995-12-13
GB8911017D0 (en) 1989-06-28
MX20639A (es) 1993-12-01
DE69018514T2 (de) 1995-09-21
FI94416C (fi) 1995-09-11
NZ233647A (en) 1992-08-26
ES2070303T3 (es) 1995-06-01
SI9010917B (sl) 1999-10-31
IE901716L (en) 1990-11-13
IL94317A (en) 1997-07-13
JP2930366B2 (ja) 1999-08-03
ATE121095T1 (de) 1995-04-15
SI9010917A (en) 1997-06-30
NO902109L (no) 1990-11-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS AG, BASEL, CH

8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC

8339 Ceased/non-payment of the annual fee