DE69916593D1 - Verfahren zur cis-selektiven katalytischen hydrierung von cyclohexylidenaminen - Google Patents
Verfahren zur cis-selektiven katalytischen hydrierung von cyclohexylidenaminenInfo
- Publication number
- DE69916593D1 DE69916593D1 DE69916593T DE69916593T DE69916593D1 DE 69916593 D1 DE69916593 D1 DE 69916593D1 DE 69916593 T DE69916593 T DE 69916593T DE 69916593 T DE69916593 T DE 69916593T DE 69916593 D1 DE69916593 D1 DE 69916593D1
- Authority
- DE
- Germany
- Prior art keywords
- cyclohexylidenamines
- selective catalytic
- catalytic hydration
- cis
- cis selective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003197 catalytic effect Effects 0.000 title 1
- 230000036571 hydration Effects 0.000 title 1
- 238000006703 hydration reaction Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/52—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH64598 | 1998-03-18 | ||
| CH64598 | 1998-03-18 | ||
| PCT/EP1999/001696 WO1999047486A1 (en) | 1998-03-18 | 1999-03-16 | Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69916593D1 true DE69916593D1 (de) | 2004-05-27 |
| DE69916593T2 DE69916593T2 (de) | 2005-05-25 |
Family
ID=4191841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69916593T Expired - Lifetime DE69916593T2 (de) | 1998-03-18 | 1999-03-16 | Verfahren zur cis-selektiven katalytischen hydrierung von cyclohexylidenaminen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6232501B1 (de) |
| EP (1) | EP1064250B1 (de) |
| JP (1) | JP2002506844A (de) |
| CN (1) | CN1216033C (de) |
| AR (1) | AR018164A1 (de) |
| AU (1) | AU759530B2 (de) |
| CA (1) | CA2323629A1 (de) |
| DE (1) | DE69916593T2 (de) |
| ES (1) | ES2217748T3 (de) |
| HU (1) | HUP0101322A3 (de) |
| IL (2) | IL138172A0 (de) |
| PT (1) | PT1064250E (de) |
| TR (1) | TR200002673T2 (de) |
| TW (1) | TWI220427B (de) |
| WO (1) | WO1999047486A1 (de) |
| ZA (1) | ZA200004624B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6500987B1 (en) | 1998-11-27 | 2002-12-31 | Teva Pharmaceutical Industries Ltd. | Sertraline hydrochloride polymorphs |
| ATE264831T1 (de) * | 1999-07-29 | 2004-05-15 | Ciba Sc Holding Ag | Verfahren zur cis-selektiven katalytischen hydrierung von cyclohexylidenaminen |
| US6495721B1 (en) | 1999-08-09 | 2002-12-17 | Teva Pharmaceutical Industries Ltd. | Sertraline hydrochloride Form II and methods for the preparation thereof |
| TWI260315B (en) | 1999-10-29 | 2006-08-21 | Ciba Sc Holding Ag | Polymorphic forms of sertraline hydrochloride |
| US7442838B2 (en) | 1999-10-29 | 2008-10-28 | Ciba Specialty Chemicals Corp. | Polymorphic forms of sertraline hydrochloride |
| IL149526A0 (en) * | 1999-11-16 | 2002-11-10 | Ciba Sc Holding Ag | Process for the preparation of ketimines |
| ES2241680T3 (es) | 1999-11-16 | 2005-11-01 | Ciba Specialty Chemicals Holding Inc. | Procedimiento para la preparacion de cetiminas. |
| IL150332A0 (en) | 1999-12-21 | 2002-12-01 | Teva Pharma | Novel sertraline hydrochloride polymorphs, processes for preparing them, compositions containing them and methods of using them |
| EP1268369A4 (de) * | 2000-03-14 | 2005-09-21 | Teva Pharma | Neues verfahren zur herstellung von (+)-cis-sertralin |
| US6723878B2 (en) | 2001-06-15 | 2004-04-20 | Orion Corporation Fermion | Method for preparing sertraline |
| WO2003093217A1 (en) | 2002-04-29 | 2003-11-13 | Teva Pharmaceutical Industries Ltd. | Process for preparation of polymorphic form ii of sertraline hydrochloride, pharmaceutical formulations and methods of administration thereof |
| ES2242555T1 (es) * | 2003-04-14 | 2005-11-16 | Teva Pharmaceutical Industries Limited | Hidrogenacion de intermediarios de imina de sertralina con catalizadores. |
| US20070260090A1 (en) | 2005-06-03 | 2007-11-08 | Hetero Drugs Limited | Highly Steroselective Synthesis of Sertraline |
| KR20100108393A (ko) * | 2007-12-21 | 2010-10-06 | 바스프 에스이 | 키랄 이민의 부분입체 선택적 전환 방법 |
| JP5502750B2 (ja) * | 2007-12-21 | 2014-05-28 | ビーエーエスエフ ソシエタス・ヨーロピア | 一段階還元的アミノ化 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536518A (en) | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
| US5290806A (en) * | 1990-03-06 | 1994-03-01 | Basf Aktiengesellschaft | 4-(4-tert-butylphenyl) cyclohexylamines, and fungicides containing same |
| GB9114948D0 (en) | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline intermediates |
| IL112569A (en) * | 1994-02-10 | 1999-12-22 | Wyeth John & Brother Ltd | Pharmaceutical compositions comprising cyclohexylamine derivatives certain such novel compounds and their preparation |
| HU222341B1 (hu) | 1996-12-18 | 2003-06-28 | Richter Gedeon Vegyészeti Gyár Rt. | Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier |
| DE19812054A1 (de) * | 1998-03-19 | 1999-09-23 | Hoechst Schering Agrevo Gmbh | Verfahren zur Herstellung 4-substituierter cis-Cyclohexylamine |
-
1999
- 1999-03-16 ES ES99915616T patent/ES2217748T3/es not_active Expired - Lifetime
- 1999-03-16 TR TR2000/02673T patent/TR200002673T2/xx unknown
- 1999-03-16 US US09/646,211 patent/US6232501B1/en not_active Expired - Lifetime
- 1999-03-16 EP EP99915616A patent/EP1064250B1/de not_active Expired - Lifetime
- 1999-03-16 CA CA002323629A patent/CA2323629A1/en not_active Abandoned
- 1999-03-16 AR ARP990101137A patent/AR018164A1/es active IP Right Grant
- 1999-03-16 WO PCT/EP1999/001696 patent/WO1999047486A1/en not_active Ceased
- 1999-03-16 IL IL13817299A patent/IL138172A0/xx not_active IP Right Cessation
- 1999-03-16 JP JP2000536684A patent/JP2002506844A/ja active Pending
- 1999-03-16 HU HU0101322A patent/HUP0101322A3/hu unknown
- 1999-03-16 CN CN998041378A patent/CN1216033C/zh not_active Expired - Fee Related
- 1999-03-16 AU AU34128/99A patent/AU759530B2/en not_active Ceased
- 1999-03-16 DE DE69916593T patent/DE69916593T2/de not_active Expired - Lifetime
- 1999-03-16 PT PT99915616T patent/PT1064250E/pt unknown
- 1999-03-17 TW TW088104122A patent/TWI220427B/zh not_active IP Right Cessation
-
2000
- 2000-08-30 IL IL138172A patent/IL138172A/en unknown
- 2000-09-04 ZA ZA200004624A patent/ZA200004624B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1293653A (zh) | 2001-05-02 |
| IL138172A (en) | 2007-09-20 |
| AU759530B2 (en) | 2003-04-17 |
| CN1216033C (zh) | 2005-08-24 |
| IL138172A0 (en) | 2001-10-31 |
| HUP0101322A2 (hu) | 2002-05-29 |
| PT1064250E (pt) | 2004-09-30 |
| DE69916593T2 (de) | 2005-05-25 |
| EP1064250B1 (de) | 2004-04-21 |
| US6232501B1 (en) | 2001-05-15 |
| JP2002506844A (ja) | 2002-03-05 |
| AR018164A1 (es) | 2001-10-31 |
| ZA200004624B (en) | 2001-11-29 |
| EP1064250A1 (de) | 2001-01-03 |
| ES2217748T3 (es) | 2004-11-01 |
| TWI220427B (en) | 2004-08-21 |
| AU3412899A (en) | 1999-10-11 |
| CA2323629A1 (en) | 1999-09-23 |
| TR200002673T2 (tr) | 2000-11-21 |
| WO1999047486A1 (en) | 1999-09-23 |
| HUP0101322A3 (en) | 2002-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: CIBA HOLDING INC., BASEL, CH |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: TEVA PHARMACEUTICAL INDUSTRIES LTD., PETAH TIQ, IL |