DE69906684D1 - Aromatische amide, ihrer verfahren zur herstellung ung verwendung als arzneimitteln - Google Patents

Aromatische amide, ihrer verfahren zur herstellung ung verwendung als arzneimitteln

Info

Publication number: DE69906684D1
Authority: DE; Germany
Prior art keywords: drugs; preparing; aromatic amides; amides; aromatic
Prior art date: 1998-01-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69906684T

Other languages

English (en)

Other versions

DE69906684T2 (de

Inventor

Jean-Luc Haesslein

Michel Klich

Patrick Laurin

Branislav Musicki

Anne-Marie Periers

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novexel SA

Original Assignee

Aventis Pharma SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-08

Filing date

1999-01-07

Publication date

2003-05-15

1998-01-08 Priority claimed from FR9800116A external-priority patent/FR2773369B1/fr

1998-10-15 Priority claimed from FR9812936A external-priority patent/FR2784681B1/fr

1999-01-07 Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA

2003-05-15 Publication of DE69906684D1 publication Critical patent/DE69906684D1/de

2003-11-06 Application granted granted Critical

2003-11-06 Publication of DE69906684T2 publication Critical patent/DE69906684T2/de

2019-01-08 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/075—Benzo[b]pyran-2-ones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Obesity (AREA)
Child & Adolescent Psychology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

DE69906684T 1998-01-08 1999-01-07 Aromatische amide, ihrer verfahren zur herstellung ung verwendung als arzneimitteln Expired - Fee Related DE69906684T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR9800116A FR2773369B1 (fr)	1998-01-08	1998-01-08	Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments
FR9812936A FR2784681B1 (fr)	1998-10-15	1998-10-15	Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments
PCT/FR1999/000014 WO1999035155A1 (fr)	1998-01-08	1999-01-07	Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number	Publication Date
DE69906684D1 true DE69906684D1 (de)	2003-05-15
DE69906684T2 DE69906684T2 (de)	2003-11-06

Family

ID=26234055

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69906684T Expired - Fee Related DE69906684T2 (de)	1998-01-08	1999-01-07	Aromatische amide, ihrer verfahren zur herstellung ung verwendung als arzneimitteln

Country Status (36)

Country	Link
US (2)	US6420538B1 (de)
EP (1)	EP1045856B1 (de)
JP (1)	JP2002500229A (de)
KR (1)	KR100604290B1 (de)
CN (2)	CN1257164C (de)
AP (1)	AP2000001857A0 (de)
AR (1)	AR015211A1 (de)
AT (1)	ATE236918T1 (de)
AU (1)	AU750742B2 (de)
BR (1)	BR9906819A (de)
CA (1)	CA2317951A1 (de)
CO (1)	CO4810298A1 (de)
CZ (1)	CZ299840B6 (de)
DE (1)	DE69906684T2 (de)
DK (1)	DK1045856T3 (de)
DZ (1)	DZ2702A1 (de)
EA (1)	EA003275B1 (de)
ES (1)	ES2192031T3 (de)
HU (1)	HUP0100847A3 (de)
ID (1)	ID27558A (de)
IL (1)	IL137201A0 (de)
MA (1)	MA26593A1 (de)
NO (1)	NO20003496L (de)
NZ (1)	NZ505523A (de)
PA (1)	PA8466601A1 (de)
PE (1)	PE20000175A1 (de)
PL (1)	PL193130B1 (de)
PT (1)	PT1045856E (de)
RS (1)	RS50047B (de)
SA (1)	SA99191247B1 (de)
SI (1)	SI1045856T1 (de)
SK (1)	SK284734B6 (de)
TN (1)	TNSN99003A1 (de)
TR (1)	TR200002009T2 (de)
TW (1)	TW538046B (de)
WO (1)	WO1999035155A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2749585B1 (fr) *	1996-06-11	1998-08-14	Hoechst Marion Roussel Inc	Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
TW538046B (en) *	1998-01-08	2003-06-21	Hoechst Marion Roussel Inc	Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof
US6916846B2 (en)	2000-05-12	2005-07-12	Merck & Co. Inc.	Coumermycin analogs as chemical dimerizers of chimeric proteins
DE60139964D1 (de) *	2000-12-15	2009-10-29	Vertex Pharma	Bakterielle Gyrase-Hemmer sowie deren Verwendung
FR2844273B1 (fr) *	2002-09-05	2008-04-04	Aventis Pharma Sa	Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) *	2002-12-06	2008-10-21	Novexel	Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
US7569591B2 (en)	2003-01-31	2009-08-04	Vertex Pharmaceuticals Incorporated	Gyrase inhibitors and uses thereof
US7618974B2 (en)	2003-01-31	2009-11-17	Vertex Pharmaceuticals Incorporated	Gyrase inhibitors and uses thereof
US8404852B2 (en)	2003-01-31	2013-03-26	Vertex Pharmaceuticals Incorporated	Gyrase inhibitors and uses thereof
US7582641B2 (en)	2003-01-31	2009-09-01	Vertex Pharmaceuticals Incorporated	Gyrase inhibitors and uses thereof
AR042956A1 (es)	2003-01-31	2005-07-13	Vertex Pharma	Inhibidores de girasa y usos de los mismos
US8193352B2 (en)	2003-01-31	2012-06-05	Vertex Pharmaceuticals Incorporated	Gyrase inhibitors and uses thereof
TW201026695A (en)	2008-12-12	2010-07-16	Astrazeneca Ab	Piperidine compounds and uses thereof-596
TW201026694A (en)	2008-12-12	2010-07-16	Astrazeneca Ab	Compound 468
TW201102065A (en)	2009-05-29	2011-01-16	Astrazeneca Ab	Heterocyclic urea derivatives and methods of use thereof
AR077971A1 (es)	2009-08-26	2011-10-05	Astrazeneca Ab	Derivados heterociclicos de urea y metodos de uso de los mismos
US8859620B2 (en)	2009-08-31	2014-10-14	University Of Notre Dame Du Lac	Phthalanilate compounds and methods of use
TWI546298B (zh)	2011-01-14	2016-08-21	維泰克斯製藥公司	旋轉酶及拓樸異構酶ｉｖ抑制劑
SG191927A1 (en)	2011-01-14	2013-08-30	Vertex Pharma	Solid forms of gyrase inhibitor (r)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl) pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1h-benzimidazol-2-yl]urea
CN103384665B (zh)	2011-01-14	2018-01-09	斯派罗吹耐姆公司	制备促旋酶和拓扑异构酶抑制剂的方法
CA2824401A1 (en)	2011-01-14	2012-07-19	Vertex Pharmaceuticals Incorporated	Solid forms of gyrase inhibitor (r)-1-ethyl-3-[5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1h-benzimidazol-2-yl]urea
EP2721026B1 (de)	2011-06-20	2016-03-02	Vertex Pharmaceuticals Incorporated	Phosphatester von gyrase und topoisomeraseinhibitoren
WO2014015105A1 (en)	2012-07-18	2014-01-23	Vertex Pharmaceuticals Incorporated	Solid forms of (r)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1h-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof
US9572809B2 (en)	2012-07-18	2017-02-21	Spero Trinem, Inc.	Combination therapy to treat Mycobacterium diseases
WO2020048949A1 (en)	2018-09-03	2020-03-12	Univerza V Ljubljani	New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria
US20250002455A1 (en)	2020-12-17	2025-01-02	Univerza V Ljubljani	New n-phenylpyrrolamide inhibitors of dna gyrase and topoisomerase iv with antibacterial activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4226978A (en) *	1978-03-13	1980-10-07	Miles Laboratories, Inc.	β-Galactosyl-umbelliferone-labeled aminoglycoside antibiotics and intermediates in their preparation
CA2249471A1 (fr)	1996-03-20	1997-09-25	Hoechst Marion Roussel	Composes tricycliques ayant une activite vis-a-vis des integrines notamment vis-a-vis de l'integrine alphavbeta3, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
FR2749585B1 (fr) *	1996-06-11	1998-08-14	Hoechst Marion Roussel Inc	Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
TW538046B (en) *	1998-01-08	2003-06-21	Hoechst Marion Roussel Inc	Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof

1998
- 1998-12-18 TW TW087121194A patent/TW538046B/zh not_active IP Right Cessation
1999
- 1999-01-06 MA MA25418A patent/MA26593A1/fr unknown
- 1999-01-06 DZ DZ990003A patent/DZ2702A1/xx active
- 1999-01-07 HU HU0100847A patent/HUP0100847A3/hu unknown
- 1999-01-07 PT PT99900500T patent/PT1045856E/pt unknown
- 1999-01-07 DE DE69906684T patent/DE69906684T2/de not_active Expired - Fee Related
- 1999-01-07 CA CA002317951A patent/CA2317951A1/fr not_active Abandoned
- 1999-01-07 SI SI9930174T patent/SI1045856T1/xx unknown
- 1999-01-07 IL IL13720199A patent/IL137201A0/xx unknown
- 1999-01-07 WO PCT/FR1999/000014 patent/WO1999035155A1/fr not_active Ceased
- 1999-01-07 DK DK99900500T patent/DK1045856T3/da active
- 1999-01-07 AP APAP/P/2000/001857A patent/AP2000001857A0/en unknown
- 1999-01-07 RS YUP-427/00A patent/RS50047B/sr unknown
- 1999-01-07 CN CNB2003101141348A patent/CN1257164C/zh not_active Expired - Fee Related
- 1999-01-07 SK SK1015-2000A patent/SK284734B6/sk not_active IP Right Cessation
- 1999-01-07 CZ CZ20002523A patent/CZ299840B6/cs not_active IP Right Cessation
- 1999-01-07 US US09/600,053 patent/US6420538B1/en not_active Expired - Fee Related
- 1999-01-07 AU AU19736/99A patent/AU750742B2/en not_active Revoked
- 1999-01-07 EA EA200000749A patent/EA003275B1/ru not_active IP Right Cessation
- 1999-01-07 BR BR9906819-2A patent/BR9906819A/pt not_active Application Discontinuation
- 1999-01-07 TR TR2000/02009T patent/TR200002009T2/xx unknown
- 1999-01-07 NZ NZ505523A patent/NZ505523A/xx unknown
- 1999-01-07 CN CNB998035033A patent/CN1269833C/zh not_active Expired - Fee Related
- 1999-01-07 EP EP99900500A patent/EP1045856B1/de not_active Expired - Lifetime
- 1999-01-07 AT AT99900500T patent/ATE236918T1/de not_active IP Right Cessation
- 1999-01-07 ES ES99900500T patent/ES2192031T3/es not_active Expired - Lifetime
- 1999-01-07 JP JP2000527551A patent/JP2002500229A/ja active Pending
- 1999-01-07 PA PA19998466601A patent/PA8466601A1/es unknown
- 1999-01-07 ID IDW20001325A patent/ID27558A/id unknown
- 1999-01-07 KR KR1020007007523A patent/KR100604290B1/ko not_active Expired - Fee Related
- 1999-01-08 PE PE1999000017A patent/PE20000175A1/es not_active Application Discontinuation
- 1999-01-08 TN TNTNSN99003A patent/TNSN99003A1/fr unknown
- 1999-01-08 AR ARP990100061A patent/AR015211A1/es not_active Application Discontinuation
- 1999-01-08 CO CO99001031A patent/CO4810298A1/es unknown
- 1999-04-05 SA SA99191247A patent/SA99191247B1/ar unknown
2000
- 2000-07-07 NO NO20003496A patent/NO20003496L/no not_active Application Discontinuation
- 2000-08-31 PL PL341590A patent/PL193130B1/pl not_active IP Right Cessation
2002
- 2002-06-05 US US10/162,852 patent/US6583119B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US6420538B1 (en)	2002-07-16
TR200002009T2 (tr)	2001-05-21
CZ299840B6 (cs)	2008-12-10
EP1045856A1 (de)	2000-10-25
ES2192031T3 (es)	2003-09-16
AR015211A1 (es)	2001-04-18
US6583119B2 (en)	2003-06-24
MA26593A1 (fr)	2004-12-20
SI1045856T1 (en)	2003-08-31
CN1257164C (zh)	2006-05-24
US20030060609A1 (en)	2003-03-27
AU1973699A (en)	1999-07-26
SK284734B6 (sk)	2005-10-06
CN1291988A (zh)	2001-04-18
TNSN99003A1 (fr)	2005-11-10
EA200000749A1 (ru)	2000-12-25
KR20010033939A (ko)	2001-04-25
NO20003496L (no)	2000-09-08
YU42700A (sh)	2002-12-10
BR9906819A (pt)	2000-10-17
PL193130B1 (pl)	2007-01-31
NZ505523A (en)	2003-01-31
HUP0100847A1 (hu)	2001-07-30
HUP0100847A3 (en)	2003-07-28
WO1999035155A1 (fr)	1999-07-15
IL137201A0 (en)	2001-07-24
EA003275B1 (ru)	2003-04-24
DZ2702A1 (fr)	2003-09-01
PT1045856E (pt)	2003-08-29
EP1045856B1 (de)	2003-04-09
TW538046B (en)	2003-06-21
AU750742B2 (en)	2002-07-25
CZ20002523A3 (cs)	2000-11-15
PA8466601A1 (es)	2000-05-24
CN1269833C (zh)	2006-08-16
SA99191247B1 (ar)	2006-09-20
NO20003496D0 (no)	2000-07-07
AP2000001857A0 (en)	2000-09-30
KR100604290B1 (ko)	2006-07-28
CA2317951A1 (fr)	1999-07-15
JP2002500229A (ja)	2002-01-08
PL341590A1 (en)	2001-04-23
ID27558A (id)	2001-04-12
CO4810298A1 (es)	1999-06-30
DE69906684T2 (de)	2003-11-06
RS50047B (sr)	2008-11-28
DK1045856T3 (da)	2003-07-21
SK10152000A3 (sk)	2001-07-10
ATE236918T1 (de)	2003-04-15
PE20000175A1 (es)	2000-03-09
CN1502617A (zh)	2004-06-09

Publication	Publication Date	Title
DE69906684D1 (de)	2003-05-15	Aromatische amide, ihrer verfahren zur herstellung ung verwendung als arzneimitteln
DE69838982D1 (de)	2008-02-21	Wegwerfunterhose und verfahren zu ihrer kontinuierlichen herstellung
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DE60007280D1 (de)	2004-01-29	Bildempfangsmaterial und verfahren zu ihrer herstellung und verwendung
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ATE236871T1 (de)	2003-04-15	Verfahren zur herstellung von aromatischen aminen
DE69909743D1 (de)	2003-08-28	Fluorierte oxyvinylverbindungen und verfahren zu ihrer herstellung und verwendung
DE69925896D1 (de)	2005-07-28	Verfahren zur herstellung von schwach-löslichen aromatischen aminen
DE69816295D1 (de)	2003-08-14	Verfahren zur herstellung von aromatischem poycarbonat
DE69819457D1 (de)	2003-12-11	Phosphorsäureester, Verfahren zu seiner Herstellung und Verwendung davon
DE69715616D1 (de)	2002-10-24	Verfahren zur herstellung von 5-amino-2,4,6-triiod-benzoldicarbonsäurederivate
ATE516267T1 (de)	2011-07-15	Vefahren zur herstellung von lactamen
DE69825880D1 (de)	2004-09-30	Verfahren zur herstellung von eprosartan
ATE280765T1 (de)	2004-11-15	Verfahren zur herstellung von eprosartan
ATE296850T1 (de)	2005-06-15	Verfahren zur herstellung von polyamiden
DE60011021D1 (de)	2004-07-01	Verfahren zur Herstellung von aromatischen Diaminen/aromatischen Dicarboxylaten
DE59900796D1 (de)	2002-03-14	Verfahren zur herstellung von polyamiden
DE59802898D1 (de)	2002-03-14	Verfahren zur herstellung von aromatischen nitrilen
DE69841956D1 (de)	2010-12-02	Aromatische amide, verfahren zu ihrer herstellung und ihre verwendung als pestizide
DE60025096D1 (de)	2006-02-02	Verfahren zur herstellung von n,n'-dialkylalkandiaminen
ATE272611T1 (de)	2004-08-15	Verfahren zur herstellung von ketiminen
ATE216873T1 (de)	2002-05-15	Verfahren zur herstellung von schweisshemmenden pulvern

Legal Events

Date	Code	Title	Description
2004-05-06	8364	No opposition during term of opposition
2006-10-26	8328	Change in the person/name/address of the agent	Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN
2007-06-28	8327	Change in the person/name/address of the patent owner	Owner name: NOVEXEL, ROMAINVILLE, FR
2009-07-30	8328	Change in the person/name/address of the agent	Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC
2010-11-18	8339	Ceased/non-payment of the annual fee