DE69902606D1 - Spiro(piperidin-4,1'-pyrrolo(3,4-c)pyrrole) - Google Patents

Spiro(piperidin-4,1'-pyrrolo(3,4-c)pyrrole)

Info

Publication number: DE69902606D1
Authority: DE; Germany
Prior art keywords: pyrrolo; spiro; pyrrole; piperidine
Prior art date: 1998-06-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69902606T

Other languages

English (en)

Other versions

DE69902606T2 (de

Inventor

Geo Adam

Frank Dautzenberg

Sabine Kolczewski

Stephan Roever

Juergen Wichmann

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-12

Filing date

1999-06-07

Publication date

2002-10-02

1999-06-07 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

2002-10-02 Publication of DE69902606D1 publication Critical patent/DE69902606D1/de

2003-04-24 Application granted granted Critical

2003-04-24 Publication of DE69902606T2 publication Critical patent/DE69902606T2/de

2019-06-08 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Addiction (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

DE69902606T 1998-06-12 1999-06-07 Spiro(piperidin-4,1'-pyrrolo(3,4-c)pyrrole) Expired - Lifetime DE69902606T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98110803		1998-06-12
EP98124119		1998-12-18

Publications (2)

Publication Number	Publication Date
DE69902606D1 true DE69902606D1 (de)	2002-10-02
DE69902606T2 DE69902606T2 (de)	2003-04-24

Family

ID=26149342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69902606T Expired - Lifetime DE69902606T2 (de)	1998-06-12	1999-06-07	Spiro(piperidin-4,1'-pyrrolo(3,4-c)pyrrole)

Country Status (27)

Country	Link
US (1)	US6075034A (de)
EP (1)	EP0963987B1 (de)
JP (1)	JP3308507B2 (de)
KR (1)	KR100346607B1 (de)
AR (1)	AR018650A1 (de)
AT (1)	ATE222908T1 (de)
AU (1)	AU749995B2 (de)
BR (1)	BR9902245A (de)
CA (1)	CA2274204C (de)
CO (1)	CO5060459A1 (de)
DE (1)	DE69902606T2 (de)
DK (1)	DK0963987T3 (de)
ES (1)	ES2181336T3 (de)
HR (1)	HRP990189A2 (de)
HU (1)	HUP9901909A3 (de)
ID (1)	ID23283A (de)
IL (1)	IL130376A0 (de)
MA (1)	MA26643A1 (de)
NO (1)	NO312069B1 (de)
NZ (1)	NZ336186A (de)
PE (1)	PE20000549A1 (de)
PL (1)	PL333694A1 (de)
PT (1)	PT963987E (de)
SG (1)	SG76623A1 (de)
TR (1)	TR199901304A2 (de)
TW (1)	TW523516B (de)
YU (1)	YU26599A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6969712B2 (en)	2000-11-15	2005-11-29	Banyu Pharmaceutical Co., Ltd.	Benzimidazole derivatives
US20030040479A1 (en) *	2001-07-02	2003-02-27	Omeros Corporation	Rotational intrathecal analgesia method and device
EP1406629A1 (de) *	2001-07-02	2004-04-14	Omeros Corporation	Verfahren zur induzierung von analgesie beinhaltend die verabreichung alternativ eines opiat-rezeptoragonists und eines opiat-rezeptor ähnlichen-1 rezeptoragonists und eine implantierbare infusionspumpe
JP2005289816A (ja)	2002-05-14	2005-10-20	Banyu Pharmaceut Co Ltd	ベンズイミダゾール誘導体
ZA200510329B (en) *	2003-05-23	2007-04-25	Zealand Pharma As	Triaza-spiro compounds as nociceptin analogues and uses thereof
WO2005060947A2 (en) *	2003-12-19	2005-07-07	Sri International	Agonist and antagonist ligands of the nociceptin receptor
JP4446978B2 (ja) *	2006-04-28	2010-04-07	トヨタ自動車株式会社	車両用駆動力制御装置
US8877779B2 (en) *	2007-03-01	2014-11-04	Mitsubishi Tanabe Pharma Corporation	Benzimidazole compound and pharmaceutical use thereof
KR101561666B1 (ko)	2014-08-12	2015-10-20	최인석	골프 퍼팅 교정장치

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5534520A (en) *	1990-04-10	1996-07-09	Fisher; Abraham	Spiro compounds containing five-membered rings
CA2226058C (en) *	1997-01-30	2008-01-29	F. Hoffmann-La Roche Ag	8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives

1999
- 1999-06-07 DE DE69902606T patent/DE69902606T2/de not_active Expired - Lifetime
- 1999-06-07 DK DK99110944T patent/DK0963987T3/da active
- 1999-06-07 ES ES99110944T patent/ES2181336T3/es not_active Expired - Lifetime
- 1999-06-07 PT PT99110944T patent/PT963987E/pt unknown
- 1999-06-07 EP EP99110944A patent/EP0963987B1/de not_active Expired - Lifetime
- 1999-06-07 AT AT99110944T patent/ATE222908T1/de active
- 1999-06-08 PE PE1999000485A patent/PE20000549A1/es not_active Application Discontinuation
- 1999-06-09 SG SG1999002779A patent/SG76623A1/en unknown
- 1999-06-09 NZ NZ336186A patent/NZ336186A/xx unknown
- 1999-06-09 CA CA002274204A patent/CA2274204C/en not_active Expired - Fee Related
- 1999-06-09 CO CO99036175A patent/CO5060459A1/es unknown
- 1999-06-09 HU HU9901909A patent/HUP9901909A3/hu unknown
- 1999-06-09 IL IL13037699A patent/IL130376A0/xx unknown
- 1999-06-10 KR KR1019990021570A patent/KR100346607B1/ko not_active Expired - Fee Related
- 1999-06-10 TR TR1999/01304A patent/TR199901304A2/xx unknown
- 1999-06-10 YU YU26599A patent/YU26599A/sh unknown
- 1999-06-10 MA MA25615A patent/MA26643A1/fr unknown
- 1999-06-10 JP JP16397599A patent/JP3308507B2/ja not_active Expired - Fee Related
- 1999-06-10 AR ARP990102765A patent/AR018650A1/es active IP Right Grant
- 1999-06-11 PL PL99333694A patent/PL333694A1/xx unknown
- 1999-06-11 BR BR9902245A patent/BR9902245A/pt not_active Application Discontinuation
- 1999-06-11 NO NO19992872A patent/NO312069B1/no unknown
- 1999-06-11 AU AU35003/99A patent/AU749995B2/en not_active Ceased
- 1999-06-11 US US09/330,857 patent/US6075034A/en not_active Expired - Fee Related
- 1999-06-11 HR HR98124119.3A patent/HRP990189A2/hr not_active Application Discontinuation
- 1999-06-14 ID IDP990577A patent/ID23283A/id unknown
- 1999-06-21 TW TW088110336A patent/TW523516B/zh active

Also Published As

Publication number	Publication date
EP0963987A3 (de)	2001-01-17
NO992872D0 (no)	1999-06-11
HU9901909D0 (en)	1999-08-30
TR199901304A3 (tr)	2000-01-21
ATE222908T1 (de)	2002-09-15
HUP9901909A3 (en)	2001-11-28
EP0963987B1 (de)	2002-08-28
ID23283A (id)	2000-04-05
TR199901304A2 (xx)	2000-01-21
PL333694A1 (en)	1999-12-20
HUP9901909A2 (hu)	2000-04-28
NO312069B1 (no)	2002-03-11
PT963987E (pt)	2003-01-31
ES2181336T3 (es)	2003-02-16
DK0963987T3 (da)	2002-12-30
MA26643A1 (fr)	2004-12-20
KR100346607B1 (ko)	2002-08-07
US6075034A (en)	2000-06-13
YU26599A (sh)	2002-09-19
SG76623A1 (en)	2000-11-21
HRP990189A2 (en)	2000-02-29
AR018650A1 (es)	2001-11-28
AU749995B2 (en)	2002-07-04
CO5060459A1 (es)	2001-07-30
TW523516B (en)	2003-03-11
JP2000053680A (ja)	2000-02-22
EP0963987A2 (de)	1999-12-15
AU3500399A (en)	1999-12-23
NO992872L (no)	1999-12-13
PE20000549A1 (es)	2000-07-24
BR9902245A (pt)	2000-03-21
DE69902606T2 (de)	2003-04-24
IL130376A0 (en)	2000-06-01
CA2274204A1 (en)	1999-12-12
CA2274204C (en)	2009-09-15
NZ336186A (en)	2000-10-27
KR20000006079A (ko)	2000-01-25
JP3308507B2 (ja)	2002-07-29

Publication	Publication Date	Title
DE59409351D1 (de)	2000-06-21	Pyrrolo[3,4-c]pyrrole
IL123835A0 (en)	1998-10-30	Pyrazolopyrimidines as CRF receptor antagonists
DE60039247D1 (de)	2008-07-31	Spiro(2h-1-benzopyran-2,4'-piperidin)derivate als glycintransporthemmer
DK0921125T3 (da)	2002-05-13	1,3,8-triazaspiro[4.5]decan-4-on-derivater
DK0837860T3 (da)	2002-05-27	Tricykliske 5,6-dihydro-9H-pyrazolo[3,4-c]-1,2,4-triazolo-[4,3-alfa]pyridiner
PL349341A1 (en)	2002-07-15	Imidazo[4,5-c]-pyridine-4-on-derivatives
DK0970957T3 (da)	2001-12-03	Diaza-spiro[3.5]nonan-derivativer
DE69902606D1 (de)	2002-10-02	Spiro(piperidin-4,1'-pyrrolo(3,4-c)pyrrole)
ZA972829B (en)	1997-10-31	Novel pyrimido [1,2-a]indoles.
ZA993853B (en)	1999-12-13	Spiro[piperidine-4,1'-pyrolo(3,4-C)pyrrole].
FI943808A7 (fi)	1994-10-24	Triatsolopyrimidiinijohdannaisia angiotensiini II:n reseptoreiden vast avaikuttajina
ZA972984B (en)	1997-11-03	Spiro[cyclopent[b]indole-piperidines.
DE59510186D1 (de)	2002-06-06	Cyaniminogruppen enthaltende Pyrrolo(3,4-c)pyrrole
FI952724A7 (fi)	1995-06-02	Allergian vastaisia triatsolo(pyrrolo, tieno tai furano)-atsepiinijohd annaisia
EP0745086A4 (de)	1997-08-13	Tricyclische spiropiperidine
EP0424315A3 (en)	1992-03-04	Tetracyclic pyrrole lactam derivatives
DE59500031D1 (de)	1996-11-28	Aminoxidgruppen enthaltende Pyrrolo[3,4-c]pyrrole als Photorezeptoren
GB9807363D0 (en)	1998-06-03	Immunosuppressant tetracyclic triterpenes
SI0880523T1 (sl)	2007-04-30	Pirazolopirimidini kot crf receptorski antagonisti

Legal Events

Date	Code	Title	Description
2003-09-25	8364	No opposition during term of opposition