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DE69841984D1 - Zusammensetzung aus nanokapseln zur behandlung von intraarticulaeren erkrankungen - Google Patents

Zusammensetzung aus nanokapseln zur behandlung von intraarticulaeren erkrankungen

Info

Publication number
DE69841984D1
DE69841984D1 DE69841984T DE69841984T DE69841984D1 DE 69841984 D1 DE69841984 D1 DE 69841984D1 DE 69841984 T DE69841984 T DE 69841984T DE 69841984 T DE69841984 T DE 69841984T DE 69841984 D1 DE69841984 D1 DE 69841984D1
Authority
DE
Germany
Prior art keywords
nanocapsules
intraarticular
diseases
treatment
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69841984T
Other languages
English (en)
Inventor
Yu Imasato
Eiziro Horisawa
Satoko Kawazoe
Tsuyoshi Hirota
Jun Yamada
Yoshiaki Kawashima
Hirofumi Takeuchi
Hiromitsu Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maruho Co Ltd
Original Assignee
Maruho Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maruho Co Ltd filed Critical Maruho Co Ltd
Application granted granted Critical
Publication of DE69841984D1 publication Critical patent/DE69841984D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69841984T 1997-09-05 1998-09-04 Zusammensetzung aus nanokapseln zur behandlung von intraarticulaeren erkrankungen Expired - Lifetime DE69841984D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24159897 1997-09-05
PCT/JP1998/003966 WO1999012571A1 (en) 1997-09-05 1998-09-04 Nanocapsule preparations for treating intraarticular diseases

Publications (1)

Publication Number Publication Date
DE69841984D1 true DE69841984D1 (de) 2010-12-16

Family

ID=17076706

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69841984T Expired - Lifetime DE69841984D1 (de) 1997-09-05 1998-09-04 Zusammensetzung aus nanokapseln zur behandlung von intraarticulaeren erkrankungen

Country Status (6)

Country Link
EP (1) EP1010435B1 (de)
JP (1) JP4272811B2 (de)
CA (1) CA2302569A1 (de)
DE (1) DE69841984D1 (de)
ES (1) ES2355186T3 (de)
WO (1) WO1999012571A1 (de)

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US8293277B2 (en) 1998-10-01 2012-10-23 Alkermes Pharma Ireland Limited Controlled-release nanoparticulate compositions
US8236352B2 (en) 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
US7521068B2 (en) 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
US7198795B2 (en) 2000-09-21 2007-04-03 Elan Pharma International Ltd. In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions
CA2475092C (en) 2002-02-04 2012-05-01 Christian F. Wertz Nanoparticulate compositions having lysozyme as a surface stabilizer
AU2003261167A1 (en) * 2002-07-16 2004-02-02 Elan Pharma International, Ltd Liquid dosage compositions of stable nanoparticulate active agents
JP4851067B2 (ja) * 2004-01-28 2012-01-11 ホソカワミクロン株式会社 ナノ粒子含有組成物およびその製造方法
EP1661559A1 (de) * 2004-11-25 2006-05-31 NanoDel Technologies GmbH Verabreichungssystem hergestellt durch ein Miniemulsionsverfahren
ATE419842T1 (de) * 2004-09-14 2009-01-15 Nanodel Technologies Gmbh Abgabevehikel mit nanoteilchen
WO2006056362A2 (en) * 2004-11-25 2006-06-01 Nanodel Technologies Gmbh Delivery vehicle manufactured by the miniemulsion method
KR101086055B1 (ko) 2009-03-06 2011-11-22 가톨릭대학교 산학협력단 온도 민감성 풀루란-락타이드 공중합체, 이로부터 형성된 나노입자, 및 그 제조방법
JP5733551B2 (ja) * 2010-03-02 2015-06-10 学校法人東京理科大学 ナノコンポジット粒子およびその製造方法
UA111162C2 (uk) 2010-08-04 2016-04-11 Флекшен Терап'Ютікс, Інк. Ін'єкційна композиція ацетоніду триамцинолону для лікування болю
WO2012169518A1 (ja) * 2011-06-07 2012-12-13 ホソカワミクロン株式会社 液状組成物及びそれを用いた化粧料並びに育毛剤
EP2739287B1 (de) * 2011-08-04 2017-07-05 Flexion Therapeutics, Inc. Corticosteroide zur behandlung von gelenkschmerzen
CA2895652C (en) 2012-12-20 2020-10-27 Omrix Biopharmaceuticals Ltd. Viral inactivated biological mixture
RU2627580C2 (ru) * 2015-11-17 2017-08-09 Александр Александрович Кролевец Способ получения нанокапсул антибиотиков тетрациклинового ряда в конжаковой камеди
RU2644726C1 (ru) * 2016-06-21 2018-02-13 Александр Александрович Кролевец Способ получения нанокапсул антисептика-стимулятора Дорогова (АСД) 2 фракция в хитозане
RU2644727C1 (ru) * 2016-06-21 2018-02-13 Александр Александрович Кролевец Способ получения нанокапсул антисептика-стимулятора Дорогова (АСД) 2 фракция
JP6842091B2 (ja) * 2017-02-10 2021-03-17 株式会社ツツミプランニング 水溶性分子複合体含有油剤の製造方法、及び分散液の製造方法
RU2020117897A (ru) * 2017-11-02 2021-12-02 Исихара Сангио Кайся, Лтд. Фармацевтическая композиция замедленного высвобождения

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US4530840A (en) * 1982-07-29 1985-07-23 The Stolle Research And Development Corporation Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents
GB8526096D0 (en) * 1985-10-22 1985-11-27 Robinson E Microcarrier
US4925678A (en) * 1987-04-01 1990-05-15 Ranney David F Endothelial envelopment drug carriers
JPH0421637A (ja) * 1990-05-11 1992-01-24 Soken Kagaku Kk キチン誘導体又はキトサンを表面に修飾した高分子微粒子並びにその製造方法
JPH0558882A (ja) * 1991-09-04 1993-03-09 Yoshiaki Kawashima ナノカプセルの製造法
DE4131562A1 (de) * 1991-09-18 1993-03-25 Medac Klinische Spezialpraep Arzneistofftraeger aus festen lipidteilchen-feste lipidnanosphaeren (sln)
JP3091285B2 (ja) * 1991-10-14 2000-09-25 ライオン株式会社 外用消炎鎮痛剤
JP3215133B2 (ja) * 1991-11-12 2001-10-02 ポーラ化成工業株式会社 消炎鎮痛外用剤
JPH05255077A (ja) * 1992-03-09 1993-10-05 Kanegafuchi Chem Ind Co Ltd 消炎鎮痛用貼付剤
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
ATE502664T1 (de) * 1993-07-19 2011-04-15 Angiotech Pharm Inc Herstellungsmethode eines stents mit anti- angiogener zusammensetzung
ES2068762B1 (es) * 1993-07-21 1995-12-01 Lipotec Sa Un nuevo preparado farmaceutico para mejorar la biodisponibilidad de drogas de dificil absorcion y procedimiento para su obtencion.
GB9412273D0 (en) * 1994-06-18 1994-08-10 Univ Nottingham Administration means
GB9416884D0 (en) * 1994-08-20 1994-10-12 Danbiosyst Uk Drug delivery compositions
DE4440337A1 (de) * 1994-11-11 1996-05-15 Dds Drug Delivery Services Ges Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit
IE75744B1 (en) * 1995-04-03 1997-09-24 Elan Corp Plc Controlled release biodegradable micro- and nanospheres containing cyclosporin
US6143211A (en) * 1995-07-21 2000-11-07 Brown University Foundation Process for preparing microparticles through phase inversion phenomena
EP1009390A4 (de) * 1997-07-02 2004-05-06 Euro Celtique Sa Verlängerte narkose in gelenken und körperzwischenräumen
ATE220564T1 (de) * 1997-08-14 2002-08-15 Sulzer Innotec Ag Zusammensetzung und vorrichtung zur reparatur von knorpelgewebe in vivo bestehend aus nanokapseln mit osteoinduktiven und/oder chondroinduktiven faktoren

Also Published As

Publication number Publication date
EP1010435A4 (de) 2006-06-14
EP1010435A1 (de) 2000-06-21
WO1999012571A1 (en) 1999-03-18
ES2355186T3 (es) 2011-03-23
JP4272811B2 (ja) 2009-06-03
CA2302569A1 (en) 1999-03-18
EP1010435B1 (de) 2010-11-03

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