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DE69839264D1 - Zusammensetzungen mit verzoegerter freisetzung und verfahren zu deren herstellung - Google Patents

Zusammensetzungen mit verzoegerter freisetzung und verfahren zu deren herstellung

Info

Publication number
DE69839264D1
DE69839264D1 DE69839264T DE69839264T DE69839264D1 DE 69839264 D1 DE69839264 D1 DE 69839264D1 DE 69839264 T DE69839264 T DE 69839264T DE 69839264 T DE69839264 T DE 69839264T DE 69839264 D1 DE69839264 D1 DE 69839264D1
Authority
DE
Germany
Prior art keywords
compositions
production
delayed release
delayed
release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69839264T
Other languages
English (en)
Other versions
DE69839264T2 (de
Inventor
Marc Pellet
Chantal Roume
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma Biotech SAS
Original Assignee
Ipsen Pharma Biotech SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26233477&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69839264(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR9704837A external-priority patent/FR2762318B1/fr
Priority claimed from FR9803666A external-priority patent/FR2776516B1/fr
Application filed by Ipsen Pharma Biotech SAS filed Critical Ipsen Pharma Biotech SAS
Publication of DE69839264D1 publication Critical patent/DE69839264D1/de
Application granted granted Critical
Publication of DE69839264T2 publication Critical patent/DE69839264T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/23Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984Microcapsule with fluid core [includes liposome]
    • Y10T428/2985Solid-walled microcapsule from synthetic polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Peptides Or Proteins (AREA)
DE69839264T 1997-04-18 1998-04-17 Zusammensetzungen mit verzoegerter freisetzung und verfahren zu deren herstellung Expired - Lifetime DE69839264T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR9704837 1997-04-18
FR9704837A FR2762318B1 (fr) 1997-04-18 1997-04-18 Compositions presentant une liberation prolongee et leur procede de preparation
FR9803666 1998-03-25
FR9803666A FR2776516B1 (fr) 1998-03-25 1998-03-25 Compositions presentant une liberation prolongee et leur procede de preparation
PCT/FR1998/000773 WO1998047489A1 (fr) 1997-04-18 1998-04-17 Compositions presentant une liberation prolongee et leur procede de preparation

Publications (2)

Publication Number Publication Date
DE69839264D1 true DE69839264D1 (de) 2008-04-30
DE69839264T2 DE69839264T2 (de) 2009-05-14

Family

ID=26233477

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69839264T Expired - Lifetime DE69839264T2 (de) 1997-04-18 1998-04-17 Zusammensetzungen mit verzoegerter freisetzung und verfahren zu deren herstellung

Country Status (22)

Country Link
US (2) US6217893B1 (de)
EP (1) EP0980240B1 (de)
JP (1) JP4557312B2 (de)
CN (2) CN1313082C (de)
AR (2) AR012448A1 (de)
AT (1) ATE389388T1 (de)
AU (1) AU741964B2 (de)
BR (1) BR9808933A (de)
CA (1) CA2286575C (de)
CZ (1) CZ297078B6 (de)
DE (1) DE69839264T2 (de)
DK (1) DK0980240T3 (de)
ES (1) ES2303353T3 (de)
HU (1) HUP0004297A2 (de)
IL (1) IL132217A (de)
MY (1) MY118835A (de)
NO (2) NO327999B1 (de)
PL (1) PL196771B1 (de)
PT (1) PT980240E (de)
RU (1) RU2198678C2 (de)
TW (1) TW577759B (de)
WO (1) WO1998047489A1 (de)

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NO995063L (no) 1999-11-15
RU2198678C2 (ru) 2003-02-20
AU7436398A (en) 1998-11-13
HUP0004297A2 (hu) 2001-08-28
BR9808933A (pt) 2000-08-01
AR012448A1 (es) 2000-10-18
TW577759B (en) 2004-03-01
EP0980240B1 (de) 2008-03-19
DK0980240T3 (da) 2008-07-28
ES2303353T3 (es) 2008-08-01
AU741964B2 (en) 2001-12-13
NO20080803L (no) 1999-11-15
NO327999B1 (no) 2009-11-09
CZ297078B6 (cs) 2006-09-13
CN1313082C (zh) 2007-05-02
DE69839264T2 (de) 2009-05-14
CN1256628A (zh) 2000-06-14
ATE389388T1 (de) 2008-04-15
CN1494900A (zh) 2004-05-12
NO995063D0 (no) 1999-10-15
US6475507B1 (en) 2002-11-05
CN1144584C (zh) 2004-04-07
WO1998047489A1 (fr) 1998-10-29
JP4557312B2 (ja) 2010-10-06
EP0980240A1 (de) 2000-02-23
PL336296A1 (en) 2000-06-19
CA2286575A1 (fr) 1998-10-29
IL132217A (en) 2004-08-31
MY118835A (en) 2005-01-31
CA2286575C (fr) 2012-06-05
CZ362699A3 (cs) 2000-04-12
HK1027983A1 (en) 2001-02-02
AR061828A2 (es) 2008-09-24
JP2002500631A (ja) 2002-01-08
PT980240E (pt) 2008-06-06
US6217893B1 (en) 2001-04-17
PL196771B1 (pl) 2008-01-31
IL132217A0 (en) 2001-03-19

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