DE69431187D1 - 14-substituierte marcfortine und derivate als antiparasitäre mittel - Google Patents

14-substituierte marcfortine und derivate als antiparasitäre mittel

Info

Publication number: DE69431187D1
Authority: DE; Germany
Prior art keywords: derivatives; antiparasitarian; marcfortine; substituted; substituted marcfortine
Prior art date: 1993-06-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69431187T

Other languages

English (en)

Other versions

DE69431187T2 (de

Inventor

H Lee

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pharmacia and Upjohn Co

Original Assignee

Pharmacia and Upjohn Co

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-16

Filing date

1994-06-07

Publication date

2002-09-19

1994-06-07 Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co

2002-09-19 Application granted granted Critical

2002-09-19 Publication of DE69431187D1 publication Critical patent/DE69431187D1/de

2003-04-10 Publication of DE69431187T2 publication Critical patent/DE69431187T2/de

2014-06-08 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Agronomy & Crop Science (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Pest Control & Pesticides (AREA)
Plant Pathology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Dentistry (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Curing Cements, Concrete, And Artificial Stone (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Enzymes And Modification Thereof (AREA)

DE69431187T 1993-06-16 1994-06-07 14-substituierte marcfortine und derivate als antiparasitäre mittel Expired - Fee Related DE69431187T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7807693A	1993-06-16	1993-06-16
PCT/US1994/006037 WO1994029319A1 (en)	1993-06-16	1994-06-07	14-substituted marcfortines and derivatives useful as antiparasitic agents

Publications (2)

Publication Number	Publication Date
DE69431187D1 true DE69431187D1 (de)	2002-09-19
DE69431187T2 DE69431187T2 (de)	2003-04-10

Family

ID=22141768

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69431187T Expired - Fee Related DE69431187T2 (de)	1993-06-16	1994-06-07	14-substituierte marcfortine und derivate als antiparasitäre mittel

Country Status (25)

Country	Link
US (1)	US5750533A (de)
EP (1)	EP0703916B1 (de)
JP (2)	JP3747059B2 (de)
KR (1)	KR100332192B1 (de)
CN (1)	CN1058266C (de)
AT (1)	ATE222255T1 (de)
AU (1)	AU686188B2 (de)
CA (1)	CA2161960A1 (de)
CZ (1)	CZ289684B6 (de)
DE (1)	DE69431187T2 (de)
DK (1)	DK0703916T3 (de)
ES (1)	ES2181722T3 (de)
FI (1)	FI956045A0 (de)
HU (1)	HU223768B1 (de)
IL (1)	IL109958A0 (de)
MY (1)	MY111601A (de)
NO (1)	NO313803B1 (de)
NZ (1)	NZ268476A (de)
PL (1)	PL180406B1 (de)
PT (1)	PT703916E (de)
RU (1)	RU2131877C1 (de)
SK (1)	SK283594B6 (de)
TW (1)	TW410227B (de)
WO (1)	WO1994029319A1 (de)
ZA (1)	ZA943959B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW334436B (en) *	1995-07-21	1998-06-21	Upjohn Co	Antiparasitic marcfortines and paraherquamides
ZA976761B (en) *	1996-09-09	1999-01-29	Upjohn Co	25 Methylene and 24,25-epoxy marcfortines and paraherquamides
WO1998021211A1 (en) *	1996-11-15	1998-05-22	Pharmacia & Upjohn Company	1- and 2-substituted marcfortines and paraherquamides as antiparasitic agents

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US390532A (en) *		1888-10-02		titscher
US5075307A (en) *	1987-07-28	1991-12-24	Merck & Co., Inc.	Paraherquamide and dihydroparaherquamide as antihelminthic agents
US4873247A (en) *	1987-11-27	1989-10-10	Goegelman Robert T	Derivatives of paraherquamide isolated from a fermentation broth active as antiparasitic agents
US4978656A (en) *	1988-08-12	1990-12-18	Merck & Co., Inc.	Synthetic derivatives of paraherquamide
US4923867A (en) *	1988-08-24	1990-05-08	Merck & Co., Inc.	Synthetic marcfortine derivatives useful as antiparasitic agents
DE3831839A1 (de) *	1988-09-20	1990-03-29	Standard Elektrik Lorenz Ag	Optischer sende- und/oder empfangsbaustein
NZ233043A (en) *	1989-03-30	1992-09-25	Merck & Co Inc	Anthelmintic heterocyclic compounds prepared by action of cunninghamella blakesleeana on (dihydro)paraherquamide
US5032595A (en) *	1989-11-24	1991-07-16	Fidia-Georgetown Institute For The Neurosciences	Method of stimulating steroidogenesis with alpidem
IE904606A1 (en) *	1989-12-21	1991-07-03	Beecham Group Plc	Novel products
GB9014194D0 (en) *	1990-06-26	1990-08-15	Pfizer Ltd	Antiparasitic agents
GB2247026B (en) *	1990-06-26	1994-09-28	Amoco Corp	Purification of a dialkylated transalkylation product
WO1992022555A1 (en) *	1991-06-17	1992-12-23	Beecham Group Plc	Paraherquamide derivatives, precursor thereof, processes for their preparation, microorganism used and their use as antiparasitic agents
JPH07501693A (ja) *	1991-11-22	1995-02-23	ジ・アップジョン・カンパニー	抗寄生虫病剤として有用なマークフォルティン／パラハークアミド誘導体

1994
- 1994-06-04 TW TW083105101A patent/TW410227B/zh active
- 1994-06-06 ZA ZA943959A patent/ZA943959B/xx unknown
- 1994-06-06 MY MYPI94001431A patent/MY111601A/en unknown
- 1994-06-07 HU HU9503594A patent/HU223768B1/hu not_active IP Right Cessation
- 1994-06-07 ES ES94920689T patent/ES2181722T3/es not_active Expired - Lifetime
- 1994-06-07 CZ CZ19953164A patent/CZ289684B6/cs not_active IP Right Cessation
- 1994-06-07 CA CA002161960A patent/CA2161960A1/en not_active Abandoned
- 1994-06-07 DK DK94920689T patent/DK0703916T3/da active
- 1994-06-07 SK SK1525-95A patent/SK283594B6/sk unknown
- 1994-06-07 KR KR1019950705698A patent/KR100332192B1/ko not_active Expired - Fee Related
- 1994-06-07 NZ NZ268476A patent/NZ268476A/xx unknown
- 1994-06-07 CN CN94192450A patent/CN1058266C/zh not_active Expired - Fee Related
- 1994-06-07 RU RU95122770A patent/RU2131877C1/ru not_active IP Right Cessation
- 1994-06-07 AT AT94920689T patent/ATE222255T1/de not_active IP Right Cessation
- 1994-06-07 FI FI956045A patent/FI956045A0/fi unknown
- 1994-06-07 PL PL94312258A patent/PL180406B1/pl not_active IP Right Cessation
- 1994-06-07 US US08/557,033 patent/US5750533A/en not_active Expired - Fee Related
- 1994-06-07 JP JP50188095A patent/JP3747059B2/ja not_active Expired - Fee Related
- 1994-06-07 WO PCT/US1994/006037 patent/WO1994029319A1/en not_active Ceased
- 1994-06-07 EP EP94920689A patent/EP0703916B1/de not_active Expired - Lifetime
- 1994-06-07 DE DE69431187T patent/DE69431187T2/de not_active Expired - Fee Related
- 1994-06-07 AU AU71389/94A patent/AU686188B2/en not_active Ceased
- 1994-06-07 PT PT94920689T patent/PT703916E/pt unknown
- 1994-06-09 IL IL10995894A patent/IL109958A0/xx unknown
1995
- 1995-12-15 NO NO19955093A patent/NO313803B1/no unknown
2005
- 2005-02-22 JP JP2005045797A patent/JP2005162766A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
WO1994029319A1 (en)	1994-12-22
ZA943959B (en)	1995-12-06
AU686188B2 (en)	1998-02-05
CZ289684B6 (cs)	2002-03-13
ATE222255T1 (de)	2002-08-15
FI956045L (fi)	1995-12-15
KR960703127A (ko)	1996-06-19
FI956045A7 (fi)	1995-12-15
ES2181722T3 (es)	2003-03-01
CZ316495A3 (en)	1996-03-13
HU9503594D0 (en)	1996-02-28
PL180406B1 (pl)	2001-01-31
PT703916E (pt)	2002-12-31
CA2161960A1 (en)	1994-12-22
RU2131877C1 (ru)	1999-06-20
JP3747059B2 (ja)	2006-02-22
DK0703916T3 (da)	2002-12-02
HU223768B1 (hu)	2005-01-28
JPH08511529A (ja)	1996-12-03
HUT74680A (en)	1997-01-28
SK152595A3 (en)	1997-06-04
JP2005162766A (ja)	2005-06-23
KR100332192B1 (ko)	2002-11-27
DE69431187T2 (de)	2003-04-10
TW410227B (en)	2000-11-01
EP0703916A1 (de)	1996-04-03
NO955093L (no)	1996-02-15
NO955093D0 (no)	1995-12-15
EP0703916B1 (de)	2002-08-14
SK283594B6 (sk)	2003-10-07
US5750533A (en)	1998-05-12
PL312258A1 (en)	1996-04-15
IL109958A0 (en)	1994-10-07
CN1125448A (zh)	1996-06-26
MY111601A (en)	2000-09-27
CN1058266C (zh)	2000-11-08
FI956045A0 (fi)	1995-12-15
NO313803B1 (no)	2002-12-02
NZ268476A (en)	1997-11-24
AU7138994A (en)	1995-01-03

Publication	Publication Date	Title
ATE215530T1 (de)	2002-04-15	7-substituierte-8-substituierte-9-substituierte amino-7-demethyl-6-deoxy-tetracycline als antibiotische mittel
ATE115134T1 (de)	1994-12-15	3-difluoromethylpyrazolcarboxamidfungizide.
DK0960107T3 (da)	2003-02-10	6-Thiosubstituerede paclitaxeler
MX9302932A (es)	1995-01-31	Nuevas 4-aza-5&-androstan-3-onas 7b-substituidas como inhibidores de la5&-reductasa.
TR200200068T2 (tr)	2002-05-21	Nematisital triflüorobütenler
DE69623899D1 (de)	2002-10-31	Behandlung von Tinnitus mit neuroprotektiven Wirkstoffen
BG101105A (bg)	1998-04-30	Заместени бензамидини, тяхното получаване и използването им като лекарствени средства
FI945957L (fi)	1994-12-19	N-substituoidut 3-atsabisyklo/3.2.0/heptaanijohdannaiset neurolepteinä jne.
ATE169637T1 (de)	1998-08-15	Derivate des dolastatin
NO890046L (no)	1989-07-21	Disubstituerte pyridiner.
FI970448A7 (fi)	1997-04-03	N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat k äyttökelpoisia neuroleptisina aineina
NO20010940D0 (no)	2001-02-23	TAN-1057 derivater
NO20001758L (no)	2000-06-05	FremgangsmÕter og blandinger for behandling av leddgikt
ATE91415T1 (de)	1993-07-15	Phenoxy- und phenylthio-, amino-substituierte benzocyclo-alkan-derivate bei der behandlung und verhuetung von arzneimittelresistenten protozoen- infektionen.
DK0595458T3 (da)	1999-06-23	Thiomarinolderivater og fremgangsmåder til fremstilling deraf
DE69431187D1 (de)	2002-09-19	14-substituierte marcfortine und derivate als antiparasitäre mittel
DK0579939T3 (da)	1999-09-20	Phospholipidderivater
ES2155476T3 (es)	2001-05-16	Aril-tio-alquil-tio-piridinas sustituidas.
DE59903977D1 (de)	2003-02-13	Imidazotriazolopyrimidine als arzneimittel mit adenosinantagonistischer wirkung
BR9611904A (pt)	1999-04-06	Dioxidos de ditiazol
CY1115806T1 (el)	2017-01-25	Παραγωγα του κυκλικου eστερα uk-2a χρησιμα στην προληψη ή την αντιμετωπιση μυκητολογικων ασθενειων
RU93053043A (ru)	1996-04-20	Новые производные тиомаринола, способ их получения, фармацевтическая композиция и способ лечения

Legal Events

Date	Code	Title	Description
2003-09-11	8364	No opposition during term of opposition
2010-04-22	8339	Ceased/non-payment of the annual fee