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DE69403084D1 - Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen - Google Patents

Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen

Info

Publication number
DE69403084D1
DE69403084D1 DE69403084T DE69403084T DE69403084D1 DE 69403084 D1 DE69403084 D1 DE 69403084D1 DE 69403084 T DE69403084 T DE 69403084T DE 69403084 T DE69403084 T DE 69403084T DE 69403084 D1 DE69403084 D1 DE 69403084D1
Authority
DE
Germany
Prior art keywords
compositions containing
benzopyrans
pharmaceutical compositions
disease
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69403084T
Other languages
English (en)
Other versions
DE69403084T2 (de
Inventor
Alexandra Mackenzie
Sandra MONAGHAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ireland Pharmaceuticals
Original Assignee
Pfizer Research and Development Co NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Research and Development Co NV SA filed Critical Pfizer Research and Development Co NV SA
Publication of DE69403084D1 publication Critical patent/DE69403084D1/de
Application granted granted Critical
Publication of DE69403084T2 publication Critical patent/DE69403084T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69403084T 1993-08-04 1994-07-18 Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen Expired - Fee Related DE69403084T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939316111A GB9316111D0 (en) 1993-08-04 1993-08-04 Benzopyrans
PCT/EP1994/002387 WO1995004730A1 (en) 1993-08-04 1994-07-18 Benzopyrans and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DE69403084D1 true DE69403084D1 (de) 1997-06-12
DE69403084T2 DE69403084T2 (de) 1997-08-14

Family

ID=10739921

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69403084T Expired - Fee Related DE69403084T2 (de) 1993-08-04 1994-07-18 Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen

Country Status (28)

Country Link
US (2) US5912244A (de)
EP (1) EP0712398B1 (de)
JP (1) JP2871098B2 (de)
KR (1) KR0175532B1 (de)
CN (1) CN1128536A (de)
AT (1) ATE152716T1 (de)
AU (1) AU684817B2 (de)
CA (1) CA2168563C (de)
CO (1) CO4230234A1 (de)
CZ (1) CZ281853B6 (de)
DE (1) DE69403084T2 (de)
DK (1) DK0712398T3 (de)
EC (1) ECSP941140A (de)
EG (1) EG20525A (de)
ES (1) ES2102870T3 (de)
FI (1) FI960487L (de)
GB (1) GB9316111D0 (de)
GR (1) GR3023521T3 (de)
HU (1) HUT75120A (de)
IL (1) IL110488A (de)
NO (1) NO960441L (de)
NZ (1) NZ271344A (de)
PE (1) PE56894A1 (de)
PL (1) PL312788A1 (de)
SG (1) SG42817A1 (de)
TW (1) TW333532B (de)
WO (1) WO1995004730A1 (de)
ZA (1) ZA945774B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573758A (en) * 1995-04-28 1996-11-12 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
HUP0101131A3 (en) * 1996-06-07 2002-04-29 Procter & Gamble Anti-inflammatory dihydrobenzopyran derivatives, medicaments containing the same, and their use
US6333352B1 (en) * 2000-04-05 2001-12-25 Mimicking Man Manually, Inc. Method of treating benign positional vertigo
RU2344123C9 (ru) * 2001-04-16 2009-05-20 Шеринг Корпорейшн 3,4-дизамещенные циклобутен-1,2-дионы как лиганды схс-хемокинового рецептора
JP2005505586A (ja) * 2001-10-04 2005-02-24 ワイス ５−ヒドロキシトリプタミン−６リガンドとしてのクロマン誘導体
PL376835A1 (pl) * 2002-11-12 2006-01-09 Warner-Lambert Company Llc Sposób pobudzania wzrostu włosów z użyciem benzopiranów
CN1917878A (zh) * 2004-02-12 2007-02-21 沃尼尔·朗伯有限责任公司 刺激毛发生长的方法
US20090110892A1 (en) * 2004-06-30 2009-04-30 General Electric Company System and method for making a graded barrier coating
US7655656B2 (en) * 2004-07-16 2010-02-02 Pfizer Inc. Hair growth promoting agents
JP2008506767A (ja) * 2004-07-19 2008-03-06 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 発毛を刺激する製剤
EP1831203A1 (de) * 2004-12-21 2007-09-12 F. Hoffmann-Roche AG Chromanderivate und deren anwendungen bei der behandlung von zns-erkrankungen

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3835011A1 (de) * 1988-10-14 1990-04-19 Merck Patent Gmbh Chromanderivate
DE3703227A1 (de) * 1987-02-04 1988-08-18 Hoechst Ag Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
DE3881714D1 (de) * 1987-02-04 1993-07-22 Hoechst Ag Alkylsubstituierte n-benzopyranyllactame, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen.
DE3811017A1 (de) * 1988-03-31 1989-10-19 Hoechst Ag Ungesaettigte n-benzopyranyllactame
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
EP0346724A1 (de) * 1988-06-16 1989-12-20 MERCK PATENT GmbH Chromanderivate
DE3824446A1 (de) * 1988-07-19 1990-01-25 Hoechst Ag, 6230 Frankfurt Verwendung substituierter 3,4-dihydro-2h-benzopyrane als heilmittel gegen obstruktive funktionsstoerungen der lunge und/oder stoerungen der ableitenden harnwege
DE3827532A1 (de) * 1988-08-13 1990-03-01 Hoechst Ag 6-aroyl-substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
DE3918041A1 (de) * 1989-06-02 1990-12-06 Merck Patent Gmbh Chromanderivate
US5061813A (en) * 1990-04-02 1991-10-29 E. R. Squibb & Sons, Inc. Substituted cyanoimino benzopyranes
GB2242628A (en) * 1990-04-06 1991-10-09 Sandoz Ltd Asthma prophylactic use of K+ channel activators
TW244350B (de) * 1991-12-14 1995-04-01 Hoechst Ag
FI930148A7 (fi) * 1992-01-18 1993-07-19 Hoechst Ag Menetelmä 6-asemassa substituoitujen kromeenien epoksidoimiseksi enantioselektiivisesti

Also Published As

Publication number Publication date
JP2871098B2 (ja) 1999-03-17
NO960441D0 (no) 1996-02-02
ES2102870T3 (es) 1997-08-01
EP0712398A1 (de) 1996-05-22
US5912244A (en) 1999-06-15
WO1995004730A1 (en) 1995-02-16
JPH08508042A (ja) 1996-08-27
SG42817A1 (en) 1997-10-17
NO960441L (no) 1996-02-02
GB9316111D0 (en) 1993-09-22
AU7494894A (en) 1995-02-28
CO4230234A1 (es) 1995-10-19
PE56894A1 (es) 1995-02-07
PL312788A1 (en) 1996-05-13
CN1128536A (zh) 1996-08-07
FI960487A7 (fi) 1996-02-02
CZ281853B6 (cs) 1997-02-12
CA2168563C (en) 1999-09-07
FI960487A0 (fi) 1996-02-02
EP0712398B1 (de) 1997-05-07
EG20525A (en) 1999-06-30
IL110488A0 (en) 1994-10-21
ZA945774B (en) 1996-02-05
CA2168563A1 (en) 1995-02-16
ATE152716T1 (de) 1997-05-15
DK0712398T3 (da) 1997-10-27
IL110488A (en) 1999-08-17
AU684817B2 (en) 1998-01-08
DE69403084T2 (de) 1997-08-14
KR0175532B1 (ko) 1999-02-18
TW333532B (en) 1998-06-11
FI960487L (fi) 1996-02-02
US6071938A (en) 2000-06-06
ECSP941140A (es) 1995-01-16
CZ33196A3 (en) 1996-05-15
NZ271344A (en) 1997-10-24
HUT75120A (en) 1997-04-28
GR3023521T3 (en) 1997-08-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PFIZER IRELAND PHARMACEUTICALS, DUBLIN, IE

8339 Ceased/non-payment of the annual fee