DE60335111D1 - Pegyliertes t20-polypeptid - Google Patents

Pegyliertes t20-polypeptid

Info

Publication number: DE60335111D1
Authority: DE; Germany
Prior art keywords: pegylated; polypeptide
Prior art date: 2002-07-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60335111T

Other languages

English (en)

Inventor

Pascal Sebastian Bailon

Chee-Youb Won

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-24

Filing date

2003-07-16

Publication date

2011-01-05

2003-07-16 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

2011-01-05 Application granted granted Critical

2011-01-05 Publication of DE60335111D1 publication Critical patent/DE60335111D1/de

2023-07-17 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
- C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
- C07K14/16—HIV-1 ; HIV-2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
AIDS & HIV (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Toxicology (AREA)
Zoology (AREA)
Hematology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE60335111T 2002-07-24 2003-07-16 Pegyliertes t20-polypeptid Expired - Lifetime DE60335111D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US39819502P	2002-07-24	2002-07-24
PCT/EP2003/007710 WO2004013164A1 (en)	2002-07-24	2003-07-16	Pegylated t20 polypeptide

Publications (1)

Publication Number	Publication Date
DE60335111D1 true DE60335111D1 (de)	2011-01-05

Family

ID=31495720

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60335111T Expired - Lifetime DE60335111D1 (de)	2002-07-24	2003-07-16	Pegyliertes t20-polypeptid

Country Status (24)

Country	Link
US (1)	US7049415B2 (de)
EP (1)	EP1527088B1 (de)
JP (1)	JP4381301B2 (de)
KR (1)	KR100637981B1 (de)
CN (1)	CN100357317C (de)
AR (1)	AR040651A1 (de)
AT (1)	ATE489401T1 (de)
AU (1)	AU2003257467B2 (de)
BR (1)	BR0312889A (de)
CA (1)	CA2493534C (de)
DE (1)	DE60335111D1 (de)
ES (1)	ES2354609T3 (de)
GT (1)	GT200300155A (de)
HR (1)	HRP20050024A2 (de)
IL (2)	IL166038A0 (de)
MX (1)	MXPA05000797A (de)
NO (1)	NO20050066L (de)
PA (1)	PA8577701A1 (de)
PE (1)	PE20040705A1 (de)
PL (1)	PL375254A1 (de)
RU (1)	RU2296769C2 (de)
TW (1)	TW200416225A (de)
WO (1)	WO2004013164A1 (de)
ZA (1)	ZA200500258B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6057287A (en)	1994-01-11	2000-05-02	Dyax Corp.	Kallikrein-binding "Kunitz domain" proteins and analogues thereof
ES2348230T3 (es)	2002-06-07	2010-12-01	Dyax Corp.	Prevención y reducción de la isquemia.
US7153829B2 (en)	2002-06-07	2006-12-26	Dyax Corp.	Kallikrein-inhibitor therapies
US20050089515A1 (en) *	2003-08-29	2005-04-28	Dyax Corp.	Poly-pegylated protease inhibitors
US20070020252A1 (en) *	2003-08-29	2007-01-25	Ladner Robert C	Modified protease inhibitors
AU2005222641B2 (en) *	2004-03-15	2011-04-07	Nektar Therapeutics	Polymer-based compositions and conjugates of HIV entry inhibitors
US7235530B2 (en)	2004-09-27	2007-06-26	Dyax Corporation	Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
WO2006108594A1 (en) *	2005-04-08	2006-10-19	Lonza Ag	Peptide synthesis of alpha-helixes on peg resin
JP2010536870A (ja) *	2007-08-21	2010-12-02	ジェンザイム・コーポレーション	カリクレイン阻害剤を用いた治療
US8637454B2 (en)	2009-01-06	2014-01-28	Dyax Corp.	Treatment of mucositis with kallikrein inhibitors
RS62853B1 (sr)	2010-01-06	2022-02-28	Takeda Pharmaceuticals Co	Proteini koji vezuju kalikrein plazme
CN103635489B (zh)	2011-01-06	2016-04-13	戴埃克斯有限公司	血浆前激肽释放酶结合蛋白
KR102555955B1 (ko)	2014-03-27	2023-07-18	다케다 파머수티컬 컴패니 리미티드	당뇨병성 황반 부종의 치료를 위한 조성물 및 방법
US10046058B2 (en)	2014-12-02	2018-08-14	Rezolute, Inc.	Use of hydrophobic organic acids to increase hydrophobicity of proteins and protein conjugates
CN108602893A (zh)	2015-12-11	2018-09-28	戴埃克斯有限公司	血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途
JP2023510854A (ja)	2020-01-13	2023-03-15	武田薬品工業株式会社	小児遺伝性血管性浮腫発作を治療するための血漿カリクレイン阻害剤及びその使用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US153694A (en) *		1874-08-04		Improvement in clothes-pounders
KR850004274A (ko) *	1983-12-13	1985-07-11	원본미기재	에리트로포이에틴의 제조방법
US5252714A (en) *	1990-11-28	1993-10-12	The University Of Alabama In Huntsville	Preparation and use of polyethylene glycol propionaldehyde
US5464933A (en) *	1993-06-07	1995-11-07	Duke University	Synthetic peptide inhibitors of HIV transmission
US5795569A (en) *	1994-03-31	1998-08-18	Amgen Inc.	Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
CH690143A5 (de) *	1995-01-27	2000-05-15	Rieter Automotive Int Ag	Lambda/4-Schallabsorber.
US5672662A (en) *	1995-07-07	1997-09-30	Shearwater Polymers, Inc.	Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US5990237A (en) *	1997-05-21	1999-11-23	Shearwater Polymers, Inc.	Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
ES2245505T3 (es) *	1998-03-23	2006-01-01	Trimeris Inc.	Metodos y composiciones para la sintesis de peptidos (t-20).
US6281331B1 (en) *	1998-03-23	2001-08-28	Trimeris, Inc.	Methods and compositions for peptide synthesis
AU1325400A (en)	1998-10-26	2000-05-15	University Of Utah Research Foundation	Method for preparation of polyethylene glycol aldehyde derivatives
WO2000032772A2 (en) *	1998-11-30	2000-06-08	Eli Lilly And Company	Erythropoietic compounds
JO2291B1 (en) *	1999-07-02	2005-09-12	اف . هوفمان لاروش ايه جي	Erythropoietin derivatives
RU2179980C2 (ru) *	2000-03-20	2002-02-27	Государственный научный центр вирусологии и биотехнологии "Вектор"	Пептид-имитатор консервативного эпитопа белка gp41 вируса иммунодефицита человека типа 1, узнаваемого вируснейтрализующими моноклональными антителами 2f5 (варианты)
KR100488351B1 (ko) *	2001-12-11	2005-05-11	선바이오(주)	신규한 폴리에틸렌글리콜-프로피온알데히드 유도체

2003
- 2003-07-16 KR KR1020057001217A patent/KR100637981B1/ko not_active Expired - Fee Related
- 2003-07-16 AT AT03766190T patent/ATE489401T1/de active
- 2003-07-16 MX MXPA05000797A patent/MXPA05000797A/es active IP Right Grant
- 2003-07-16 CN CNB038176807A patent/CN100357317C/zh not_active Expired - Fee Related
- 2003-07-16 AU AU2003257467A patent/AU2003257467B2/en not_active Ceased
- 2003-07-16 EP EP03766190A patent/EP1527088B1/de not_active Expired - Lifetime
- 2003-07-16 HR HR20050024A patent/HRP20050024A2/xx not_active Application Discontinuation
- 2003-07-16 IL IL16603803A patent/IL166038A0/xx unknown
- 2003-07-16 ES ES03766190T patent/ES2354609T3/es not_active Expired - Lifetime
- 2003-07-16 CA CA2493534A patent/CA2493534C/en not_active Expired - Fee Related
- 2003-07-16 PL PL03375254A patent/PL375254A1/xx not_active Application Discontinuation
- 2003-07-16 DE DE60335111T patent/DE60335111D1/de not_active Expired - Lifetime
- 2003-07-16 BR BR0312889-0A patent/BR0312889A/pt not_active IP Right Cessation
- 2003-07-16 RU RU2005105577/04A patent/RU2296769C2/ru not_active IP Right Cessation
- 2003-07-16 JP JP2004525219A patent/JP4381301B2/ja not_active Expired - Fee Related
- 2003-07-16 WO PCT/EP2003/007710 patent/WO2004013164A1/en not_active Ceased
- 2003-07-18 TW TW092119716A patent/TW200416225A/zh unknown
- 2003-07-21 US US10/623,873 patent/US7049415B2/en not_active Expired - Fee Related
- 2003-07-21 PA PA20038577701A patent/PA8577701A1/es unknown
- 2003-07-22 AR AR20030102621A patent/AR040651A1/es unknown
- 2003-07-22 PE PE2003000729A patent/PE20040705A1/es not_active Application Discontinuation
- 2003-07-23 GT GT200300155A patent/GT200300155A/es unknown
2004
- 2004-12-29 IL IL166038A patent/IL166038A/en not_active IP Right Cessation
2005
- 2005-01-06 NO NO20050066A patent/NO20050066L/no not_active Application Discontinuation
- 2005-01-11 ZA ZA2005/00258A patent/ZA200500258B/en unknown

Also Published As

Publication number	Publication date
ATE489401T1 (de)	2010-12-15
NO20050066L (no)	2005-04-22
RU2005105577A (ru)	2005-10-27
CN1671736A (zh)	2005-09-21
BR0312889A (pt)	2005-06-14
WO2004013164A1 (en)	2004-02-12
CA2493534C (en)	2010-01-26
ES2354609T3 (es)	2011-03-16
TW200416225A (en)	2004-09-01
GT200300155A (es)	2004-03-15
PL375254A1 (en)	2005-11-28
HRP20050024A2 (en)	2006-02-28
KR100637981B1 (ko)	2006-10-23
AU2003257467A1 (en)	2004-02-23
IL166038A0 (en)	2006-01-15
US7049415B2 (en)	2006-05-23
RU2296769C2 (ru)	2007-04-10
JP2006511455A (ja)	2006-04-06
KR20050027257A (ko)	2005-03-18
EP1527088A1 (de)	2005-05-04
US20040049018A1 (en)	2004-03-11
MXPA05000797A (es)	2005-04-19
CN100357317C (zh)	2007-12-26
IL166038A (en)	2010-11-30
JP4381301B2 (ja)	2009-12-09
PA8577701A1 (es)	2004-02-07
CA2493534A1 (en)	2004-02-12
AR040651A1 (es)	2005-04-13
ZA200500258B (en)	2006-01-25
PE20040705A1 (es)	2004-10-14
AU2003257467B2 (en)	2008-02-28
EP1527088B1 (de)	2010-11-24

Publication	Publication Date	Title
EP1732581A4 (de)	2008-06-04	Polypeptidtransduktion und fusogene peptide
EP1499352A4 (de)	2006-10-11	Rekombinante anti-interleukin-9-antikörper
DK1543038T4 (da)	2020-11-09	Proteinoprensning
DK1504108T3 (da)	2013-06-10	Lentivirusvektor
ATE327696T1 (de)	2006-06-15	Kippschirm
ATE489401T1 (de)	2010-12-15	Pegyliertes t20-polypeptid
DE60327407D1 (de)	2009-06-10	Immunmodulierende peptide
DK1490404T3 (da)	2013-09-16	Laktoferrin
NO20034432D0 (no)	2003-10-03	Interferon gamma polypeptidvarianter
PL375218A1 (en)	2005-11-28	Recombinant protein variants
GB0201679D0 (en)	2002-03-13	Polypeptide variants
EP1359932A4 (de)	2004-06-30	Tip39 polypeptide
EP1614695A4 (de)	2006-10-04	Polypeptid
NO20032963D0 (no)	2003-06-27	Peptidforbindelser
GB0218977D0 (en)	2002-09-25	Polypeptide
IL166037A0 (en)	2006-01-15	Pegylated t1249 polypeptide
GB0223193D0 (en)	2002-11-13	Polypeptide
NO20050436D0 (no)	2005-01-26	Beta-lagnedbrytende peptider
NO20053512D0 (no)	2005-07-18	IL-8-liknende proteiner
GB0208925D0 (en)	2002-05-29	Polypeptide
GB0206684D0 (en)	2002-05-01	Novel proteins
NO20052608D0 (no)	2005-05-31	Midkinlignende protein
EP1477559A4 (de)	2005-12-07	Neues polypeptid
GB0207652D0 (en)	2002-05-15	Protein structure
ATA522002A (de)	2003-07-15	Vmp-bindungsprotein