DE60332656D1 - Topische stabilisierte dosierungsformen für prostaglandin e-verbindungen - Google Patents
Topische stabilisierte dosierungsformen für prostaglandin e-verbindungenInfo
- Publication number
- DE60332656D1 DE60332656D1 DE60332656T DE60332656T DE60332656D1 DE 60332656 D1 DE60332656 D1 DE 60332656D1 DE 60332656 T DE60332656 T DE 60332656T DE 60332656 T DE60332656 T DE 60332656T DE 60332656 D1 DE60332656 D1 DE 60332656D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- prostaglandin
- dosage forms
- aqueous
- film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical class CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 title abstract 2
- 239000002552 dosage form Substances 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- -1 PGE compounds Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000004067 bulking agent Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000007909 solid dosage form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pregnancy & Childbirth (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/336,481 US6841574B2 (en) | 2003-01-03 | 2003-01-03 | Topical stabilized prostaglandin E compound dosage forms |
| PCT/US2003/041658 WO2004062632A1 (en) | 2003-01-03 | 2003-12-31 | Topical stabilized prostaglandin e compound dosage forms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60332656D1 true DE60332656D1 (de) | 2010-07-01 |
Family
ID=32681022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60332656T Expired - Lifetime DE60332656D1 (de) | 2003-01-03 | 2003-12-31 | Topische stabilisierte dosierungsformen für prostaglandin e-verbindungen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6841574B2 (de) |
| EP (1) | EP1585483B1 (de) |
| JP (2) | JP2006514068A (de) |
| KR (2) | KR101174788B1 (de) |
| CN (1) | CN100574763C (de) |
| AT (1) | ATE468098T1 (de) |
| AU (1) | AU2003300113B2 (de) |
| BR (1) | BR0317924A (de) |
| CA (1) | CA2512015C (de) |
| DE (1) | DE60332656D1 (de) |
| DK (1) | DK1585483T3 (de) |
| ES (1) | ES2343246T3 (de) |
| IL (1) | IL169425A (de) |
| PT (1) | PT1585483E (de) |
| WO (1) | WO2004062632A1 (de) |
| ZA (1) | ZA200505321B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050004226A1 (en) * | 1998-12-10 | 2005-01-06 | Nexmed (Holdings), Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
| GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
| US20050181030A1 (en) * | 2003-01-03 | 2005-08-18 | Mo Y. J. | Topical stabilized prostaglandin E compound dosage forms |
| JP4667369B2 (ja) | 2003-03-21 | 2011-04-13 | ネックスメド ホールディングス インコーポレイテッド | 早漏を治療するための組成物および方法 |
| WO2005051960A2 (en) * | 2003-11-22 | 2005-06-09 | Midwest Research Laboratories, Llc | Hydrocarbyl aminohydrocarbonoates and aminohydrocarbonol hydrocarbonoates as antimicrobial and antiviral agents |
| GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
| CA2610465A1 (en) * | 2005-06-03 | 2006-12-14 | Duramed Pharmaceuticals, Inc. | Pharmaceutical compositions comprising prostanoid-receptor agonists and methods of making and using the same |
| ITMI20051417A1 (it) * | 2005-07-22 | 2007-01-23 | Mipharm S P A | Formulazione topica in forma di gel contenente come ingredienti attivi ciclovit e lidocaina |
| CN101321511A (zh) * | 2005-12-06 | 2008-12-10 | 莫诺索尔克斯有限公司 | 递送活性剂的局部用薄膜组合物 |
| GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
| GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
| US7560489B2 (en) * | 2006-10-11 | 2009-07-14 | Nexmed Holdings, Inc. | Stabilized prostaglandin E composition |
| GB0620685D0 (en) * | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
| CN104887388B (zh) | 2009-06-03 | 2018-01-09 | 弗赛特影像5股份有限公司 | 前段药物输送 |
| JP2014510156A (ja) | 2011-04-07 | 2014-04-24 | ネクスメッド ホールディングス，インコーポレイテッド | レイノー病を治療する方法および組成物 |
| CA2848397C (en) | 2011-09-14 | 2022-04-26 | Forsight Vision5, Inc. | Ocular insert apparatus and methods |
| JP6298068B2 (ja) | 2012-10-26 | 2018-03-20 | フォーサイト・ビジョン５・インコーポレイテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ５，Ｉｎｃ． | 眼に対する薬物徐放用眼科システム |
| US8900625B2 (en) * | 2012-12-15 | 2014-12-02 | Nexmed Holdings, Inc. | Antimicrobial compounds and methods of use |
| WO2016168141A1 (en) | 2015-04-13 | 2016-10-20 | Forsight Vision5, Inc. | Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent |
| WO2019142015A1 (es) * | 2018-01-18 | 2019-07-25 | Caicedo Pinto, David Felipe | Composicion farmaceutica para la disfuncion erectil de administracion transdermica via uretral en gotas |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3883576A (en) * | 1971-02-02 | 1975-05-13 | Upjohn Co | Prostaglandin E{HD 3 {B analogs |
| US3826823A (en) * | 1972-09-25 | 1974-07-30 | Syntex Inc | Stabilized prostaglandin preparations |
| US3875300A (en) * | 1972-12-18 | 1975-04-01 | Ortho Pharma Corp | Composition for sustained release of a medicament and method of using same |
| US4136162A (en) * | 1974-07-05 | 1979-01-23 | Schering Aktiengesellschaft | Medicament carriers in the form of film having active substance incorporated therein |
| US5017382A (en) * | 1979-03-21 | 1991-05-21 | National Research Development Corporation | Controlled release compositions (II) |
| JPS5770816A (en) * | 1980-10-17 | 1982-05-01 | Ono Pharmaceut Co Ltd | Multilayered film preparation of prostagladin of prolonged action |
| JPS58134019A (ja) * | 1982-02-05 | 1983-08-10 | Ono Pharmaceut Co Ltd | プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法 |
| JPS5948409A (ja) * | 1982-09-10 | 1984-03-19 | Teikoku Seiyaku Kk | 矯正的歯牙移動促進剤 |
| JPS6185315A (ja) * | 1984-10-04 | 1986-04-30 | Teikoku Seiyaku Kk | シ−ト状製剤 |
| IE59361B1 (en) * | 1986-01-24 | 1994-02-09 | Akzo Nv | Pharmaceutical preparation for obtaining a highly viscous hydrogel or suspension |
| US5219885A (en) * | 1987-02-16 | 1993-06-15 | Froelich Juergen | Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration |
| BR9203277A (pt) * | 1992-08-21 | 1994-03-01 | Cesar Roberto Dias Nahoum | Utilizaccao de drogas eretogenicas e respectivas metodologias de aplicacao |
| US5380760A (en) * | 1993-11-19 | 1995-01-10 | Minnesota Mining And Manufacturing Company | Transdermal prostaglandin composition |
| SE9501670L (sv) * | 1995-05-05 | 1996-06-10 | Perstorp Ab | Omläggningsset |
| US6593369B2 (en) * | 1997-10-20 | 2003-07-15 | Vivus, Inc. | Methods, compositions, and kits for enhancing female sexual desire and responsiveness |
| US20020004529A1 (en) * | 1997-10-20 | 2002-01-10 | Gary W. Neal | Methods, compositions, and kits for enhancing female sexual desire and responsiveness |
| US6414028B1 (en) * | 1997-11-05 | 2002-07-02 | Nexmed Holdings, Inc. | Topical compositions containing prostaglandin E1 |
| US6046244A (en) * | 1997-11-05 | 2000-04-04 | Nexmed Holdings, Inc. | Topical compositions for prostaglandin E1 delivery |
| US5942545A (en) * | 1998-06-15 | 1999-08-24 | Macrochem Corporation | Composition and method for treating penile erectile dysfunction |
| CA2335736A1 (en) * | 1998-06-25 | 1999-12-29 | Lavipharm Laboratories, Inc. | A device and method for the treatment of erectile dysfunction |
| US6323241B1 (en) * | 2000-01-10 | 2001-11-27 | Nexmed (Holdings) Inc. | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
| KR100402334B1 (ko) * | 2000-06-23 | 2003-10-22 | 환인제약 주식회사 | 알프로스타딜 외용제 |
-
2003
- 2003-01-03 US US10/336,481 patent/US6841574B2/en not_active Expired - Lifetime
- 2003-12-31 EP EP03800371A patent/EP1585483B1/de not_active Expired - Lifetime
- 2003-12-31 PT PT03800371T patent/PT1585483E/pt unknown
- 2003-12-31 CA CA2512015A patent/CA2512015C/en not_active Expired - Lifetime
- 2003-12-31 WO PCT/US2003/041658 patent/WO2004062632A1/en not_active Ceased
- 2003-12-31 CN CN200380110112A patent/CN100574763C/zh not_active Expired - Fee Related
- 2003-12-31 BR BR0317924-9A patent/BR0317924A/pt not_active Application Discontinuation
- 2003-12-31 DE DE60332656T patent/DE60332656D1/de not_active Expired - Lifetime
- 2003-12-31 JP JP2004566647A patent/JP2006514068A/ja active Pending
- 2003-12-31 DK DK03800371.1T patent/DK1585483T3/da active
- 2003-12-31 KR KR1020117008180A patent/KR101174788B1/ko not_active Expired - Fee Related
- 2003-12-31 AT AT03800371T patent/ATE468098T1/de active
- 2003-12-31 AU AU2003300113A patent/AU2003300113B2/en not_active Expired
- 2003-12-31 KR KR1020057012502A patent/KR20050098853A/ko not_active Withdrawn
- 2003-12-31 ES ES03800371T patent/ES2343246T3/es not_active Expired - Lifetime
-
2005
- 2005-06-27 IL IL169425A patent/IL169425A/en unknown
- 2005-06-30 ZA ZA200505321A patent/ZA200505321B/en unknown
-
2011
- 2011-09-14 JP JP2011200752A patent/JP5395138B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2512015C (en) | 2011-11-08 |
| KR101174788B1 (ko) | 2012-08-20 |
| WO2004062632A1 (en) | 2004-07-29 |
| ES2343246T3 (es) | 2010-07-27 |
| PT1585483E (pt) | 2010-06-17 |
| EP1585483A4 (de) | 2006-04-19 |
| ZA200505321B (en) | 2006-04-26 |
| KR20050098853A (ko) | 2005-10-12 |
| EP1585483B1 (de) | 2010-05-19 |
| CN1756532A (zh) | 2006-04-05 |
| HK1090293A1 (zh) | 2006-12-22 |
| CN100574763C (zh) | 2009-12-30 |
| AU2003300113B2 (en) | 2010-03-11 |
| CA2512015A1 (en) | 2004-07-29 |
| DK1585483T3 (da) | 2010-07-19 |
| EP1585483A1 (de) | 2005-10-19 |
| KR20110042138A (ko) | 2011-04-22 |
| IL169425A (en) | 2010-11-30 |
| ATE468098T1 (de) | 2010-06-15 |
| JP5395138B2 (ja) | 2014-01-22 |
| US20040131664A1 (en) | 2004-07-08 |
| BR0317924A (pt) | 2005-11-29 |
| JP2012036196A (ja) | 2012-02-23 |
| US6841574B2 (en) | 2005-01-11 |
| JP2006514068A (ja) | 2006-04-27 |
| AU2003300113A1 (en) | 2004-08-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE468098T1 (de) | Topische stabilisierte dosierungsformen für prostaglandin e-verbindungen | |
| RU2370485C2 (ru) | Амидоацетонитрильные производные | |
| BRPI0606318A2 (pt) | composto, composição, e, uso de um composto | |
| EA201000089A1 (ru) | Применение гомо- и сополимеров для стабилизации составов активных ингредиентов | |
| MX2007013065A (es) | Derivados de dihidrobenzofurano y usos de los mismos. | |
| CL2012000374A1 (es) | Metodo para la preparacion de una composicion saborizante activa que comprende una primera reaccion entre un compuesto amino y un carbonilo, resultando una primera mezcla de intermediarios, una segunda reaccion con un segundo compuesto amino solo o en combinacion con un compuesto carbinilo, resultando una segunda mezcla de intermediarios, reacciones serparadas adicionales con compuestos de otras clases quimicas, ultima reaccion que comprende una mezcla de todas las mezclas de intermediarios anteriores. | |
| TR200602857T1 (tr) | Bitki zararlılarının kontrol edilmesi için bileşimler. | |
| BRPI0607455A2 (pt) | composto, processo para a preparação do mesmo, uso de um composto, e composição farmacêutica | |
| BRPI0920355B8 (pt) | composições farmacêuticas tópicas estáveis de ozenoxacina e uso de ozenoxacina | |
| EA201000436A1 (ru) | Стероидные [3,2-с]пиразольные соединения, обладающие глюкокортикоидной активностью | |
| SV2009003221A (es) | Composiciones de fenilalquilamino carbamato ref. prd2743svpct | |
| EA200900267A1 (ru) | КОМПОЗИЦИЯ ДЛЯ АЭРОЗОЛЬНОЙ ИНГАЛЯЦИИ β-АГОНИСТОВ И СТЕРОИДОВ | |
| DK1297013T3 (da) | Anvendelse af TACI som antitumormiddel | |
| NO20081207L (no) | Isoquinolines as IGF-1R inhibitors | |
| ATE420918T1 (de) | Sauerstoffbarriereformulierungen | |
| TW200640532A (en) | Oral compositions containing biphenol antibacterial compounds | |
| PE20080949A1 (es) | Azolilmetiloxiranos, su uso para combatir hongos fitopatogenos, asi como productos que los contienen | |
| RU2008112676A (ru) | Противоопухолевое средство | |
| CY1109430T1 (el) | Υγρη συνθεση περιλαμβανουσα αργινινη και α-λιποϊκο οξυ και χρηση αυτης για βελτιωση της σεξουαλικης λειτουργιας | |
| DK1885187T3 (da) | Fremgangsmåde til behandling af lægemiddelresistent cancer | |
| UY29069A1 (es) | Uso de compuestos tpo miméticos y composiciones farmacéuticas para el tratamiento de la anemia | |
| TR200801031T2 (tr) | Bitki zararlılarının kontrol edilmesi için bileşimler. | |
| TW200531693A (en) | Prolonged-release diuretic compositions | |
| EA200601818A1 (ru) | Фармацевтический препарат, содержащий дроспиренон, для нанесения на поверхность кожи | |
| DE60309926D1 (de) | Steroid-verbindungen mit anti-tumoraler wirkung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |