DE60323874D1 - Formulierung zur rektalen verabreichung thrombolytischer wirkstoffe - Google Patents
Formulierung zur rektalen verabreichung thrombolytischer wirkstoffeInfo
- Publication number
- DE60323874D1 DE60323874D1 DE60323874T DE60323874T DE60323874D1 DE 60323874 D1 DE60323874 D1 DE 60323874D1 DE 60323874 T DE60323874 T DE 60323874T DE 60323874 T DE60323874 T DE 60323874T DE 60323874 D1 DE60323874 D1 DE 60323874D1
- Authority
- DE
- Germany
- Prior art keywords
- formulation
- active substances
- rectal administration
- thrombolytic active
- thrombolytic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000013543 active substance Substances 0.000 title 1
- 239000003146 anticoagulant agent Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000002537 thrombolytic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- A61K38/166—Streptokinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20020336A CU23203A1 (es) | 2002-12-27 | 2002-12-27 | Formulaciones que contienen agentes de accion trombolitica para su administracion por via rectal |
| PCT/CU2003/000020 WO2004058219A1 (es) | 2002-12-27 | 2003-12-22 | Formulaciones para administrar por vía rectal agentes con acción trombolítica |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60323874D1 true DE60323874D1 (de) | 2008-11-13 |
Family
ID=40091670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60323874T Expired - Lifetime DE60323874D1 (de) | 2002-12-27 | 2003-12-22 | Formulierung zur rektalen verabreichung thrombolytischer wirkstoffe |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US10213379B2 (de) |
| EP (1) | EP1576951B1 (de) |
| JP (1) | JP2006512374A (de) |
| KR (1) | KR100804013B1 (de) |
| CN (1) | CN100335128C (de) |
| AR (1) | AR042646A1 (de) |
| AT (1) | ATE409460T1 (de) |
| AU (1) | AU2003291916B2 (de) |
| BR (1) | BRPI0317780B8 (de) |
| CA (1) | CA2527572C (de) |
| CU (1) | CU23203A1 (de) |
| DE (1) | DE60323874D1 (de) |
| DK (1) | DK1576951T3 (de) |
| ES (1) | ES2315537T3 (de) |
| MX (1) | MXPA05007006A (de) |
| MY (1) | MY142241A (de) |
| PT (1) | PT1576951E (de) |
| WO (1) | WO2004058219A1 (de) |
| ZA (1) | ZA200505399B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660429B (zh) * | 2005-01-10 | 2011-09-07 | 王振军 | 基质金属蛋白酶（mmp）抑制剂用于治疗痔的新用途 |
| CN100364610C (zh) * | 2005-12-12 | 2008-01-30 | 北京大学 | 提高蚓激酶口服吸收生物利用度的方法 |
| CN102091326B (zh) * | 2009-12-15 | 2013-04-03 | 上海凯茂生物医药有限公司 | 治疗因肛门皮下的静脉丛发生扩大或曲张所引发的痔类疾病的经皮给药制剂及制备方法 |
| CN102552916B (zh) * | 2010-12-09 | 2014-04-23 | 上海凯茂生物医药有限公司 | 水杨酸钠的新用途 |
| ES2688119T3 (es) * | 2015-07-08 | 2018-10-31 | Dr. Falk Pharma Gmbh | Formulación farmacéutica para el tratamiento de cambios inflamatorios del recto |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3804600A1 (de) * | 1988-02-13 | 1989-08-24 | Basf Ag | Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz |
| GB8808810D0 (en) | 1988-04-14 | 1988-05-18 | Biopharm Clinical Research Ltd | Heparin-containing formulations |
| US5098707A (en) * | 1989-07-31 | 1992-03-24 | Merck & Co., Inc. | Imidazole compounds and their use as transglutaminase inhibitors |
| US5885967A (en) | 1994-03-04 | 1999-03-23 | Eli Lilly And Company | Antithrombotic agents |
| US5720962A (en) * | 1995-10-04 | 1998-02-24 | Au Pharmaceuticals, Inc. | Analgesic lotion for hemorrhoids and method of making such lotion |
| US5837688A (en) * | 1996-11-27 | 1998-11-17 | Gelfand; Mathew I. | Use of thrombolytic reagents for prevention of vascular disease |
| CA2305726A1 (en) * | 1997-10-07 | 1999-04-15 | Regents Of The University Of California | Treating occlusive peripheral vascular disease and coronary disease with combinations of heparin and an adenoside a2 agonist, or with adenosine |
| AU7965000A (en) * | 1999-09-27 | 2001-04-30 | Jun-Suk Oh | Use of analgesics as digestive and medicines for expectorating and transdermal therapeutic system using the same |
-
2002
- 2002-12-27 CU CU20020336A patent/CU23203A1/es unknown
-
2003
- 2003-12-22 MX MXPA05007006A patent/MXPA05007006A/es active IP Right Grant
- 2003-12-22 BR BRPI0317780A patent/BRPI0317780B8/pt not_active IP Right Cessation
- 2003-12-22 DK DK03767381T patent/DK1576951T3/da active
- 2003-12-22 CN CNB2003801088471A patent/CN100335128C/zh not_active Expired - Lifetime
- 2003-12-22 DE DE60323874T patent/DE60323874D1/de not_active Expired - Lifetime
- 2003-12-22 JP JP2004562479A patent/JP2006512374A/ja not_active Ceased
- 2003-12-22 ES ES03767381T patent/ES2315537T3/es not_active Expired - Lifetime
- 2003-12-22 EP EP03767381A patent/EP1576951B1/de not_active Expired - Lifetime
- 2003-12-22 CA CA2527572A patent/CA2527572C/en not_active Expired - Lifetime
- 2003-12-22 AR ARP030104771A patent/AR042646A1/es not_active Application Discontinuation
- 2003-12-22 US US10/540,296 patent/US10213379B2/en active Active
- 2003-12-22 WO PCT/CU2003/000020 patent/WO2004058219A1/es not_active Ceased
- 2003-12-22 AT AT03767381T patent/ATE409460T1/de active
- 2003-12-22 PT PT03767381T patent/PT1576951E/pt unknown
- 2003-12-22 AU AU2003291916A patent/AU2003291916B2/en not_active Ceased
- 2003-12-22 KR KR1020057011945A patent/KR100804013B1/ko not_active Expired - Lifetime
- 2003-12-26 MY MYPI20035014A patent/MY142241A/en unknown
-
2005
- 2005-07-04 ZA ZA200505399A patent/ZA200505399B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004058219A1 (es) | 2004-07-15 |
| CA2527572A1 (en) | 2004-07-15 |
| EP1576951A1 (de) | 2005-09-21 |
| CU23203A1 (es) | 2007-05-18 |
| KR20050088219A (ko) | 2005-09-02 |
| JP2006512374A (ja) | 2006-04-13 |
| MXPA05007006A (es) | 2005-08-18 |
| AU2003291916A1 (en) | 2004-07-22 |
| ES2315537T3 (es) | 2009-04-01 |
| AU2003291916B2 (en) | 2007-03-08 |
| CA2527572C (en) | 2010-03-30 |
| PT1576951E (pt) | 2009-01-09 |
| CN100335128C (zh) | 2007-09-05 |
| CN1738602A (zh) | 2006-02-22 |
| DK1576951T3 (da) | 2009-02-02 |
| ZA200505399B (en) | 2006-04-26 |
| BRPI0317780B8 (pt) | 2021-05-25 |
| ATE409460T1 (de) | 2008-10-15 |
| BR0317780A (pt) | 2005-11-22 |
| BRPI0317780B1 (pt) | 2018-11-21 |
| KR100804013B1 (ko) | 2008-02-18 |
| US20070166298A1 (en) | 2007-07-19 |
| AR042646A1 (es) | 2005-06-29 |
| US10213379B2 (en) | 2019-02-26 |
| MY142241A (en) | 2010-11-15 |
| EP1576951B1 (de) | 2008-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |