CU23203A1 - Formulaciones que contienen agentes de accion trombolitica para su administracion por via rectal - Google Patents
Formulaciones que contienen agentes de accion trombolitica para su administracion por via rectalInfo
- Publication number
- CU23203A1 CU23203A1 CU20020336A CU20020336A CU23203A1 CU 23203 A1 CU23203 A1 CU 23203A1 CU 20020336 A CU20020336 A CU 20020336A CU 20020336 A CU20020336 A CU 20020336A CU 23203 A1 CU23203 A1 CU 23203A1
- Authority
- CU
- Cuba
- Prior art keywords
- trombolitic
- administration
- action
- containing agents
- formulations containing
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000014617 hemorrhoid Diseases 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 230000000149 penetrating effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 230000002537 thrombolytic effect Effects 0.000 abstract 1
- 230000001732 thrombotic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- A61K38/166—Streptokinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Formulaciones farmacÉuticas en forma de supositorio que contienen agentes con accion trombolítica capaces de penetrar en la mucosa rectal, para el tratamiento de la enfermedad hemorroidal aguda y/o de origen trombotico.
Priority Applications (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20020336A CU23203A1 (es) | 2002-12-27 | 2002-12-27 | Formulaciones que contienen agentes de accion trombolitica para su administracion por via rectal |
| CNB2003801088471A CN100335128C (zh) | 2002-12-27 | 2003-12-22 | 血栓溶解活性剂的直肠给药制剂 |
| JP2004562479A JP2006512374A (ja) | 2002-12-27 | 2003-12-22 | 血栓溶解剤を含む直腸投与用製剤 |
| BRPI0317780A BRPI0317780B8 (pt) | 2002-12-27 | 2003-12-22 | uso de supositório de estreptoquinase com ação trombolítica |
| DE60323874T DE60323874D1 (de) | 2002-12-27 | 2003-12-22 | Formulierung zur rektalen verabreichung thrombolytischer wirkstoffe |
| US10/540,296 US10213379B2 (en) | 2002-12-27 | 2003-12-22 | Formulations for the rectal administration of thrombolytically-active agents |
| AT03767381T ATE409460T1 (de) | 2002-12-27 | 2003-12-22 | Formulierung zur rektalen verabreichung thrombolytischer wirkstoffe |
| CA2527572A CA2527572C (en) | 2002-12-27 | 2003-12-22 | Formulations containing thrombolytic agents for rectal administration |
| ARP030104771A AR042646A1 (es) | 2002-12-27 | 2003-12-22 | Formulaciones que contienen agentes de accion trombolitica para su administracion por via rectal |
| AU2003291916A AU2003291916B2 (en) | 2002-12-27 | 2003-12-22 | Formulations for the rectal administration of thrombolytically-active agents |
| KR1020057011945A KR100804013B1 (ko) | 2002-12-27 | 2003-12-22 | 혈전용해 활성제의 직장 투여용 제제 |
| DK03767381T DK1576951T3 (da) | 2002-12-27 | 2003-12-22 | Sammensætninger til rektal indgivelse af trombolytisk aktive midler |
| MXPA05007006A MXPA05007006A (es) | 2002-12-27 | 2003-12-22 | Formulaciones que contienen agentes de accion trombolitica para su administracion por via rectal. |
| PCT/CU2003/000020 WO2004058219A1 (es) | 2002-12-27 | 2003-12-22 | Formulaciones para administrar por vía rectal agentes con acción trombolítica |
| EP03767381A EP1576951B1 (en) | 2002-12-27 | 2003-12-22 | Formulations for the rectal administration of thrombolytically-active agents |
| PT03767381T PT1576951E (pt) | 2002-12-27 | 2003-12-22 | Formulações para administração rectal de agentes com acção trombolitica |
| ES03767381T ES2315537T3 (es) | 2002-12-27 | 2003-12-22 | Formulaciones para la administracion rectal de agentes tromboliticamente activos. |
| MYPI20035014A MY142241A (en) | 2002-12-27 | 2003-12-26 | Formulations containing thrombolytic agents for rectal administration |
| ZA200505399A ZA200505399B (en) | 2002-12-27 | 2005-07-04 | Formulations for the rectal administration of thrombolytically-active agents |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20020336A CU23203A1 (es) | 2002-12-27 | 2002-12-27 | Formulaciones que contienen agentes de accion trombolitica para su administracion por via rectal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU23203A1 true CU23203A1 (es) | 2007-05-18 |
Family
ID=40091670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20020336A CU23203A1 (es) | 2002-12-27 | 2002-12-27 | Formulaciones que contienen agentes de accion trombolitica para su administracion por via rectal |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US10213379B2 (es) |
| EP (1) | EP1576951B1 (es) |
| JP (1) | JP2006512374A (es) |
| KR (1) | KR100804013B1 (es) |
| CN (1) | CN100335128C (es) |
| AR (1) | AR042646A1 (es) |
| AT (1) | ATE409460T1 (es) |
| AU (1) | AU2003291916B2 (es) |
| BR (1) | BRPI0317780B8 (es) |
| CA (1) | CA2527572C (es) |
| CU (1) | CU23203A1 (es) |
| DE (1) | DE60323874D1 (es) |
| DK (1) | DK1576951T3 (es) |
| ES (1) | ES2315537T3 (es) |
| MX (1) | MXPA05007006A (es) |
| MY (1) | MY142241A (es) |
| PT (1) | PT1576951E (es) |
| WO (1) | WO2004058219A1 (es) |
| ZA (1) | ZA200505399B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660429B (zh) * | 2005-01-10 | 2011-09-07 | 王振军 | 基质金属蛋白酶(mmp)抑制剂用于治疗痔的新用途 |
| CN100364610C (zh) * | 2005-12-12 | 2008-01-30 | 北京大学 | 提高蚓激酶口服吸收生物利用度的方法 |
| CN102091326B (zh) * | 2009-12-15 | 2013-04-03 | 上海凯茂生物医药有限公司 | 治疗因肛门皮下的静脉丛发生扩大或曲张所引发的痔类疾病的经皮给药制剂及制备方法 |
| CN102552916B (zh) * | 2010-12-09 | 2014-04-23 | 上海凯茂生物医药有限公司 | 水杨酸钠的新用途 |
| ES2688119T3 (es) * | 2015-07-08 | 2018-10-31 | Dr. Falk Pharma Gmbh | Formulación farmacéutica para el tratamiento de cambios inflamatorios del recto |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3804600A1 (de) * | 1988-02-13 | 1989-08-24 | Basf Ag | Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz |
| GB8808810D0 (en) | 1988-04-14 | 1988-05-18 | Biopharm Clinical Research Ltd | Heparin-containing formulations |
| US5098707A (en) * | 1989-07-31 | 1992-03-24 | Merck & Co., Inc. | Imidazole compounds and their use as transglutaminase inhibitors |
| US5885967A (en) | 1994-03-04 | 1999-03-23 | Eli Lilly And Company | Antithrombotic agents |
| US5720962A (en) * | 1995-10-04 | 1998-02-24 | Au Pharmaceuticals, Inc. | Analgesic lotion for hemorrhoids and method of making such lotion |
| US5837688A (en) * | 1996-11-27 | 1998-11-17 | Gelfand; Mathew I. | Use of thrombolytic reagents for prevention of vascular disease |
| CA2305726A1 (en) * | 1997-10-07 | 1999-04-15 | Regents Of The University Of California | Treating occlusive peripheral vascular disease and coronary disease with combinations of heparin and an adenoside a2 agonist, or with adenosine |
| AU7965000A (en) * | 1999-09-27 | 2001-04-30 | Jun-Suk Oh | Use of analgesics as digestive and medicines for expectorating and transdermal therapeutic system using the same |
-
2002
- 2002-12-27 CU CU20020336A patent/CU23203A1/es unknown
-
2003
- 2003-12-22 MX MXPA05007006A patent/MXPA05007006A/es active IP Right Grant
- 2003-12-22 BR BRPI0317780A patent/BRPI0317780B8/pt not_active IP Right Cessation
- 2003-12-22 DK DK03767381T patent/DK1576951T3/da active
- 2003-12-22 CN CNB2003801088471A patent/CN100335128C/zh not_active Expired - Lifetime
- 2003-12-22 DE DE60323874T patent/DE60323874D1/de not_active Expired - Lifetime
- 2003-12-22 JP JP2004562479A patent/JP2006512374A/ja not_active Ceased
- 2003-12-22 ES ES03767381T patent/ES2315537T3/es not_active Expired - Lifetime
- 2003-12-22 EP EP03767381A patent/EP1576951B1/en not_active Expired - Lifetime
- 2003-12-22 CA CA2527572A patent/CA2527572C/en not_active Expired - Lifetime
- 2003-12-22 AR ARP030104771A patent/AR042646A1/es not_active Application Discontinuation
- 2003-12-22 US US10/540,296 patent/US10213379B2/en active Active
- 2003-12-22 WO PCT/CU2003/000020 patent/WO2004058219A1/es not_active Ceased
- 2003-12-22 AT AT03767381T patent/ATE409460T1/de active
- 2003-12-22 PT PT03767381T patent/PT1576951E/pt unknown
- 2003-12-22 AU AU2003291916A patent/AU2003291916B2/en not_active Ceased
- 2003-12-22 KR KR1020057011945A patent/KR100804013B1/ko not_active Expired - Lifetime
- 2003-12-26 MY MYPI20035014A patent/MY142241A/en unknown
-
2005
- 2005-07-04 ZA ZA200505399A patent/ZA200505399B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004058219A1 (es) | 2004-07-15 |
| CA2527572A1 (en) | 2004-07-15 |
| EP1576951A1 (en) | 2005-09-21 |
| KR20050088219A (ko) | 2005-09-02 |
| JP2006512374A (ja) | 2006-04-13 |
| MXPA05007006A (es) | 2005-08-18 |
| AU2003291916A1 (en) | 2004-07-22 |
| ES2315537T3 (es) | 2009-04-01 |
| AU2003291916B2 (en) | 2007-03-08 |
| CA2527572C (en) | 2010-03-30 |
| PT1576951E (pt) | 2009-01-09 |
| CN100335128C (zh) | 2007-09-05 |
| CN1738602A (zh) | 2006-02-22 |
| DK1576951T3 (da) | 2009-02-02 |
| ZA200505399B (en) | 2006-04-26 |
| BRPI0317780B8 (pt) | 2021-05-25 |
| ATE409460T1 (de) | 2008-10-15 |
| BR0317780A (pt) | 2005-11-22 |
| BRPI0317780B1 (pt) | 2018-11-21 |
| KR100804013B1 (ko) | 2008-02-18 |
| US20070166298A1 (en) | 2007-07-19 |
| DE60323874D1 (de) | 2008-11-13 |
| AR042646A1 (es) | 2005-06-29 |
| US10213379B2 (en) | 2019-02-26 |
| MY142241A (en) | 2010-11-15 |
| EP1576951B1 (en) | 2008-10-01 |
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