[go: up one dir, main page]

DE60317225D1 - Minimal nachgiebiger volumen-effizienter kolben für osmotische medikamentenabgabesysteme - Google Patents

Minimal nachgiebiger volumen-effizienter kolben für osmotische medikamentenabgabesysteme

Info

Publication number
DE60317225D1
DE60317225D1 DE60317225T DE60317225T DE60317225D1 DE 60317225 D1 DE60317225 D1 DE 60317225D1 DE 60317225 T DE60317225 T DE 60317225T DE 60317225 T DE60317225 T DE 60317225T DE 60317225 D1 DE60317225 D1 DE 60317225D1
Authority
DE
Germany
Prior art keywords
capsule
piston
agent
osmotic
interior surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60317225T
Other languages
English (en)
Other versions
DE60317225T2 (de
Inventor
Scott D Lautenbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intarcia Therapeutics Inc
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of DE60317225D1 publication Critical patent/DE60317225D1/de
Application granted granted Critical
Publication of DE60317225T2 publication Critical patent/DE60317225T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14513Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60317225T 2002-06-26 2003-06-25 Minimal nachgiebiger volumen-effizienter kolben für osmotische medikamentenabgabesysteme Expired - Lifetime DE60317225T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39200402P 2002-06-26 2002-06-26
US392004P 2002-06-26
PCT/US2003/020130 WO2004002565A1 (en) 2002-06-26 2003-06-25 Minimally compliant, volume efficient piston for osmotic drug delivery systems

Publications (2)

Publication Number Publication Date
DE60317225D1 true DE60317225D1 (de) 2007-12-13
DE60317225T2 DE60317225T2 (de) 2008-05-29

Family

ID=30000792

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60317225T Expired - Lifetime DE60317225T2 (de) 2002-06-26 2003-06-25 Minimal nachgiebiger volumen-effizienter kolben für osmotische medikamentenabgabesysteme

Country Status (19)

Country Link
US (3) US6939556B2 (de)
EP (1) EP1551493B1 (de)
JP (1) JP4485945B2 (de)
KR (1) KR101046903B1 (de)
CN (1) CN100453130C (de)
AT (1) ATE376854T1 (de)
AU (1) AU2003256308B2 (de)
BR (1) BR0312429A (de)
CA (1) CA2490544C (de)
DE (1) DE60317225T2 (de)
EC (1) ECSP055578A (de)
ES (1) ES2295642T3 (de)
IL (1) IL165975A (de)
MX (1) MXPA05000224A (de)
NO (1) NO20050368L (de)
NZ (1) NZ537628A (de)
TW (1) TW200531709A (de)
WO (1) WO2004002565A1 (de)
ZA (1) ZA200500744B (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
US7258869B1 (en) * 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
KR20050088196A (ko) * 2002-12-19 2005-09-02 알자 코포레이션 안정한 비수성 단일 상 겔 및 이식가능한 장치로부터전달하기 위한 이의 제형
BRPI0408862A (pt) * 2003-03-31 2006-04-11 Alza Corp bomba osmótica com dispositivo para dissipar pressão interna
MXPA05010604A (es) * 2003-03-31 2005-11-23 Alza Corp Sistema de administracion osmotica y metodo para disminuir los tiempos de arranque para sistemas de administracion osmotica.
EP1694310A2 (de) * 2003-11-06 2006-08-30 Alza Corporation Modularer imbibitionsratenreduzierer zur verwendung mit einer implantierbaren osmotischen pumpe
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
US8058291B2 (en) 2005-04-06 2011-11-15 Adamas Pharmaceuticals, Inc. Methods and compositions for the treatment of CNS-related conditions
MX2007006120A (es) 2004-11-23 2007-12-07 Adamas Pharmaceuticals Inc Metodo y composicion para administrar a un sujeto un antagonista del receptor de nmda.
US8389578B2 (en) 2004-11-24 2013-03-05 Adamas Pharmaceuticals, Inc Composition and method for treating neurological disease
EP1877077A2 (de) * 2005-02-03 2008-01-16 Intarcia Therapeutics, Inc. Implantierbare interferonhaltige vorrichtung
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US7959938B2 (en) 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
US20070208041A1 (en) * 2005-10-13 2007-09-06 Stamler Jonathan S Compositions for the treatment and prevention of heart disease and methods of using same
WO2007140416A2 (en) 2006-05-30 2007-12-06 Intarcia Therapeutics, Inc. Two-piece, internal-channel osmotic delivery system flow modulator
JP5048773B2 (ja) 2006-08-09 2012-10-17 インターシア セラピューティクス,インコーポレイティド 浸透圧式デリバリーシステム及びピストンアセンブリー
NZ580447A (en) 2007-04-23 2011-06-30 Intarcia Therapeutics Inc Suspension formulations of insulinotropic peptides and uses thereof
US8105261B2 (en) * 2007-07-02 2012-01-31 Cardiac Pacemakers, Inc. Osmotic devices and methods for diuretic therapy
US8394644B2 (en) 2007-11-08 2013-03-12 Honeywell International Inc. Microfluidic osmotic pump
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
CN102281865B (zh) * 2008-10-15 2017-04-05 精达制药公司 高浓缩药物颗粒、制剂、混悬剂及其应用
AU2010265863C1 (en) * 2009-06-26 2012-11-01 Taris Biomedical Llc Implantable drug delivery devices and methods of making the same
RU2753280C2 (ru) 2009-09-28 2021-08-12 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
US20120277180A1 (en) 2009-09-30 2012-11-01 Vitapath Genetics, Inc Cofactors and Methods for Use for Individuals
BR112012013487A2 (pt) 2009-12-02 2017-10-03 Adamas Pharmaceuticals Inc Composições de amantadina e métodos de uso
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
EP2731599B1 (de) 2011-07-15 2018-10-31 NuSirt Sciences, Inc. Zusammensetzungen und verfahren zur modulierung metabolischer signalwege
US9198454B2 (en) 2012-03-08 2015-12-01 Nusirt Sciences, Inc. Compositions, methods, and kits for regulating energy metabolism
EA201892121A1 (ru) * 2012-10-12 2019-02-28 Эли Лилли Энд Компани Химические двигатели и способы их использования, особенно при введении сильно вязких текучих сред
CN108452311A (zh) 2012-11-13 2018-08-28 纽斯尔特科学公司 用于增强能量代谢的组合物和方法
CN105101958B (zh) 2013-01-15 2019-05-17 纽斯尔特科学公司 治疗肺病状
WO2014138214A1 (en) * 2013-03-05 2014-09-12 Taris Biomedical, Inc. Drug delivery devices and methods for controlled drug release through device orifice
CN105228627B (zh) 2013-03-15 2018-07-13 纽斯尔特科学公司 亮氨酸和烟酸降低脂质水平
WO2014204933A1 (en) 2013-06-17 2014-12-24 Adamas Pharmaceuticals, Inc. Amantadine compositions and methods of use
SG11201607075TA (en) 2014-02-27 2016-09-29 Nusirt Sciences Inc Compositions and methods for the reduction or prevention of hepatic steatosis
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
ES2968262T3 (es) 2015-06-03 2024-05-08 I2O Therapeutics Inc Sistemas de colocación de implantes
RU2739384C2 (ru) 2015-11-05 2020-12-23 Дзе Дженерал Хоспитал Корпорейшн Интратекальная доставка последовательностей нуклеиновых кислот, кодирующих abcd1, для лечения адреномиелоневропатии
CN109069480A (zh) 2015-12-30 2018-12-21 阿达玛斯医药公司 用于治疗与癫痫相关的病症的方法和组合物
CN109310743A (zh) 2016-05-16 2019-02-05 因塔西亚制药公司 胰高血糖素受体选择性多肽及其使用方法
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
JP7626362B2 (ja) 2016-10-20 2025-02-07 ペプトロン インコーポレイテッド 中枢神経系に神経保護ポリペプチドを送達する方法
MX2019008006A (es) 2017-01-03 2019-08-29 Intarcia Therapeutics Inc Metodos que comprenden la administracion continua de un agonista del receptor de glp-1 y la co-administracion de un farmaco.
ES3036733T3 (en) 2017-02-17 2025-09-23 Lilly Co Eli Processes and devices for delivery of fluid by chemical reaction
JP2020510028A (ja) 2017-03-08 2020-04-02 インターシア セラピューティクス,インコーポレイティド 薬物送達デバイスから吐き気誘発性化合物の投与のための装置及び方法
WO2018200885A1 (en) 2017-04-26 2018-11-01 Neurocentria, Inc. Magnesium compositions and methods of use
WO2019050791A1 (en) 2017-09-08 2019-03-14 Eli Lilly And Company SYSTEM FOR CONTROLLING GENERATION OF GAS IN A DRUG DELIVERY DEVICE
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
US12128201B2 (en) 2018-08-23 2024-10-29 Baywind Bioventures Capsule device for delivery of active agent to gastrointestinal tract
MX2021004185A (es) 2018-10-11 2021-09-08 Intarcia Therapeutics Inc Polipeptidos analogos de la amilina humana y sus metodos de uso.
JP2022513945A (ja) 2018-12-19 2022-02-09 イーライ リリー アンド カンパニー 治療用流体の送達のためのデバイス
ES2987026T3 (es) 2018-12-19 2024-11-13 Lilly Co Eli Dispositivos y procesos para el suministro de fluidos terapéuticos
WO2025160155A1 (en) 2024-01-22 2025-07-31 The Broad Institute, Inc. Epigenetic targeting of prion diseases

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753651A (en) 1982-08-30 1988-06-28 Alza Corporation Self-driven pump
US4765989A (en) 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US4558888A (en) * 1983-09-19 1985-12-17 Minnesota Mining And Manufacturing Company Strip of binding tape
US4874388A (en) 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US5034229A (en) 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5728088A (en) 1988-12-13 1998-03-17 Alza Corporation Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
US4969884A (en) 1988-12-28 1990-11-13 Alza Corporation Osmotically driven syringe
US5234424A (en) 1988-12-28 1993-08-10 Alza Corporation Osmotically driven syringe
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5030216A (en) * 1989-12-15 1991-07-09 Alza Corporation Osmotically driven syringe
US5324280A (en) 1990-04-02 1994-06-28 Alza Corporation Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
US5234692A (en) 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5180591A (en) 1990-07-11 1993-01-19 Alza Corporation Delivery device with a protective sleeve
US5443459A (en) 1991-01-30 1995-08-22 Alza Corporation Osmotic device for delayed delivery of agent
US5861166A (en) 1991-03-12 1999-01-19 Alza Corporation Delivery device providing beneficial agent stability
CN2085662U (zh) * 1991-03-29 1991-10-02 毕勇 药物″渗透泵″的生产装置
US5137727A (en) 1991-06-12 1992-08-11 Alza Corporation Delivery device providing beneficial agent stability
EP0664118B1 (de) 1991-10-04 1999-08-25 Yoshitomi Pharmaceutical Industries, Ltd. Tablette mit verzögerter freisetzung
EP0607321A1 (de) 1991-10-10 1994-07-27 Alza Corporation Osmotische wirkstoffabgabevorrichtung mit hydrophabem wandmaterial
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5308348A (en) 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5209746A (en) 1992-02-18 1993-05-11 Alza Corporation Osmotically driven delivery devices with pulsatile effect
US5456679A (en) 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5221278A (en) 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect
US5260069A (en) * 1992-11-27 1993-11-09 Anda Sr Pharmaceuticals Inc. Pulsatile particles drug delivery system
US5540665A (en) 1994-01-31 1996-07-30 Alza Corporation Gas driven dispensing device and gas generating engine therefor
US5458888A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
US5690952A (en) 1995-06-07 1997-11-25 Judy A. Magruder et al. Implantable system for delivery of fluid-sensitive agents to animals
US6132420A (en) 1996-02-02 2000-10-17 Alza Corporation Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems
US6395292B2 (en) 1996-02-02 2002-05-28 Alza Corporation Sustained delivery of an active agent using an implantable system
US6156331A (en) 1996-02-02 2000-12-05 Alza Corporation Sustained delivery of an active agent using an implantable system
US6261584B1 (en) 1996-02-02 2001-07-17 Alza Corporation Sustained delivery of an active agent using an implantable system
PL189137B1 (pl) * 1996-02-02 2005-06-30 Alza Corp Implantowane urządzenie do dostarczania substancji aktywnej
ZA981610B (en) 1997-03-24 1999-08-26 Alza Corp Self adjustable exit port.
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
MY125849A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
WO1999033446A1 (en) 1997-12-29 1999-07-08 Alza Corporation Osmotic delivery system with membrane plug retention mechanism
JP2002532406A (ja) 1998-12-17 2002-10-02 アルザ・コーポレーション 複合コーティングによる液体充填ゼラチンカプセルの放出制御システムへの変換
AU2002225870B2 (en) * 2000-11-03 2006-09-21 Intarcia Therapeutics, Inc. Method for short-term and long-term drug dosimetry

Also Published As

Publication number Publication date
EP1551493A1 (de) 2005-07-13
CA2490544C (en) 2011-04-19
MXPA05000224A (es) 2005-06-03
JP4485945B2 (ja) 2010-06-23
KR101046903B1 (ko) 2011-07-06
ZA200500744B (en) 2006-03-29
AU2003256308B2 (en) 2008-07-03
CN1671439A (zh) 2005-09-21
US7112335B2 (en) 2006-09-26
ATE376854T1 (de) 2007-11-15
IL165975A0 (en) 2006-01-15
KR20050026416A (ko) 2005-03-15
US20040019345A1 (en) 2004-01-29
CA2490544A1 (en) 2004-01-08
US20060111693A1 (en) 2006-05-25
WO2004002565A1 (en) 2004-01-08
NO20050368L (no) 2005-01-24
NZ537628A (en) 2005-12-23
IL165975A (en) 2009-07-20
US20070088337A1 (en) 2007-04-19
CN100453130C (zh) 2009-01-21
US6939556B2 (en) 2005-09-06
ES2295642T3 (es) 2008-04-16
TW200531709A (en) 2005-10-01
BR0312429A (pt) 2005-04-19
ECSP055578A (es) 2005-04-18
JP2005530588A (ja) 2005-10-13
DE60317225T2 (de) 2008-05-29
HK1080402A1 (en) 2006-04-28
EP1551493B1 (de) 2007-10-31
AU2003256308A1 (en) 2004-01-19

Similar Documents

Publication Publication Date Title
DE60317225D1 (de) Minimal nachgiebiger volumen-effizienter kolben für osmotische medikamentenabgabesysteme
WO2000040218A3 (en) Osmotic delivery system having space efficient piston
BRPI0407366A (pt) Envoltório com liberação de pressão por ação de came
CO5700800A2 (es) Dispositivo de administracion controlada de farmaco para paciente
DE60023361D1 (de) Ventil für osmotische vorrichtungen
HUP0302377A2 (hu) Fecskendő, nyomáskamra és eljárás folyékony gyógyszer injekciózására
KR910700083A (ko) 삼투압 구동식 주사기
DE602004026828D1 (de) Pharmazeutische abgabesysteme
AU1808797A (en) Cartridge-based drug delivery device
WO2002085428A3 (en) Implantable osmotic pump
CO5021220A1 (es) Dispositivo de suministro de agentes beneficos y metodo para su elaboracion
BR9812367A (pt) Recipiente com uma guarnição vedada e bomba para a bertura da referida vedação
CA2455525A1 (en) Elongated syringe
EP2011541A3 (de) Schlauchsystem für eine Einspritzdüse, Quetschventil und Druckmessschnittstelle
ES267593Y (es) Dispositivo osmotico para el suministro controlado de un medicamento en un ambiente fluido.
EP2446911A3 (de) In sich geschlossenes tragbares Gerät zur Verabreichung einer Medikamentenlösung
WO2004009152A3 (en) Infusion pump and method for use
DE59811108D1 (de) Spender für medien
AU2002366758A1 (en) Hair treatment fluid application device
MX2008001043A (es) Contenedor.
ES2410157T3 (es) Sistema de bomba de pistón
BR9708126A (pt) Bomba de platina
ZA200508781B (en) Osmotic delivery system and method for decreasing start-up times for osmotic delivery systems
WO2017045959A3 (en) Drug delivery device
EP1516714A3 (de) Flüssigkeitstransportssystem in eine Vorform

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: INTARCIA THERAPEUTICS, INC., EMERYVILLE, CALIF, US

8364 No opposition during term of opposition