[go: up one dir, main page]

DE60315992D1 - Überwachung von zellen - Google Patents

Überwachung von zellen

Info

Publication number
DE60315992D1
DE60315992D1 DE60315992T DE60315992T DE60315992D1 DE 60315992 D1 DE60315992 D1 DE 60315992D1 DE 60315992 T DE60315992 T DE 60315992T DE 60315992 T DE60315992 T DE 60315992T DE 60315992 D1 DE60315992 D1 DE 60315992D1
Authority
DE
Germany
Prior art keywords
cells
monitoring
chamber
microfluidic
inhibited
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60315992T
Other languages
English (en)
Other versions
DE60315992T2 (de
Inventor
Christopher Robin Lowe
Craig J Gershater
Colin Alexander Davidson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smart Holograms Ltd
Original Assignee
Smart Holograms Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smart Holograms Ltd filed Critical Smart Holograms Ltd
Publication of DE60315992D1 publication Critical patent/DE60315992D1/de
Application granted granted Critical
Publication of DE60315992T2 publication Critical patent/DE60315992T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0645Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/161Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/163Biocompatibility
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/161Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165Specific details about hydrophobic, oleophobic surfaces
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/019Biological contaminants; Fouling
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486Counting the particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60315992T 2002-07-09 2003-07-09 Überwachung von zellen Expired - Fee Related DE60315992T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0215879.8A GB0215879D0 (en) 2002-07-09 2002-07-09 Monitoring of cells
GB0215879 2002-07-09
PCT/GB2003/002976 WO2004005922A2 (en) 2002-07-09 2003-07-09 Monitoring of cells

Publications (2)

Publication Number Publication Date
DE60315992D1 true DE60315992D1 (de) 2007-10-11
DE60315992T2 DE60315992T2 (de) 2008-01-24

Family

ID=9940123

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60315992T Expired - Fee Related DE60315992T2 (de) 2002-07-09 2003-07-09 Überwachung von zellen

Country Status (9)

Country Link
US (1) US20060051733A1 (de)
EP (1) EP1535064B1 (de)
JP (1) JP2005532060A (de)
AT (1) ATE371867T1 (de)
AU (1) AU2003246931B2 (de)
CA (1) CA2491896A1 (de)
DE (1) DE60315992T2 (de)
GB (1) GB0215879D0 (de)
WO (1) WO2004005922A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004098741A2 (en) 2003-04-30 2004-11-18 Biovitesse Apparatus and method for detecting live cells with an integrated filter and growth detection device
DE102004005337A1 (de) * 2004-02-04 2005-08-25 Studiengesellschaft Kohle Mbh Mikrofluidische Chips mit immanenten hydrophilen Oberflächen
JP2005253412A (ja) * 2004-03-15 2005-09-22 Masayasu Suzuki マイクロウェルアレイチップ、その製造方法及び被検体の活性検定方法
US7160425B2 (en) * 2004-03-25 2007-01-09 Hewlett-Packard Development Company, L.P. Cell transporter for a biodevice
ITPI20040046A1 (it) * 2004-06-18 2004-09-18 Univ Pisa Bioreattore per lo studio degli effetti sulle attivita' cellulari di stimoli imposti
KR100790880B1 (ko) * 2006-07-05 2008-01-02 삼성전자주식회사 자성 비드가 결합되어 있는 소수성 다공성 중합체가 벽면에결합되어 있는 마이크로채널 또는 마이크로챔버를포함하는 미세유동장치 및 그를 이용하는 방법
WO2009157211A1 (ja) * 2008-06-26 2009-12-30 国立大学法人東京大学 培養細胞の活性計測方法、マイクロチャンバ、マイクロチャンバアレイ、培養容器および培養細胞の活性計測装置
AU2009262959A1 (en) * 2008-06-27 2009-12-30 Massachusetts Institute Of Technology Microfluidic droplets for metabolic engineering and other applications
CN103782153A (zh) * 2011-04-27 2014-05-07 俄亥俄州大学 用于检测生物膜的方法和装置
DE102011075762A1 (de) * 2011-05-12 2012-11-15 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Analysegerät zur automatisierten Bestimmung einer Messgröße einer Messflüssigkeit
US9204821B2 (en) * 2012-05-09 2015-12-08 Isense Medical Corp. Method of and apparatus for detecting upper respiratory bacterial infection from exhaled mammalian breath and colorimetric sensor array cartridge
GB201512600D0 (en) * 2015-07-17 2015-08-26 Koniku Ltd Cell culture, transport and investigation
JPWO2017068778A1 (ja) * 2015-10-22 2018-08-09 パナソニックIpマネジメント株式会社 電気化学測定デバイスおよび電気化学測定システム
JP2020510417A (ja) 2017-02-17 2020-04-09 コニク インコーポレイテッド 検出のためのシステム
CN108362629B (zh) * 2018-02-09 2021-02-05 中国计量科学研究院 大肠杆菌o157:h7单个活菌的快速检测方法及试剂盒
WO2024100056A1 (en) * 2022-11-08 2024-05-16 Lumicks Ca Holding B.V. Microfluidic device

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2966904B2 (ja) * 1990-08-08 1999-10-25 株式会社日立製作所 細胞の処理方法、および処理装置
US5474774A (en) * 1994-03-25 1995-12-12 Jlb, Inc. Adhesion inhibiting composition
GB9406142D0 (en) * 1994-03-28 1994-05-18 British Tech Group A sensor
EP1064353B1 (de) * 1998-03-18 2002-11-06 Massachusetts Institute Of Technology Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane
WO1999067639A1 (en) * 1998-06-25 1999-12-29 Caliper Technologies Corporation High throughput methods, systems and apparatus for performing cell based screening assays
US6561208B1 (en) * 2000-04-14 2003-05-13 Nanostream, Inc. Fluidic impedances in microfluidic system
US6653124B1 (en) * 2000-11-10 2003-11-25 Cytoplex Biosciences Inc. Array-based microenvironment for cell culturing, cell monitoring and drug-target validation
US20040077075A1 (en) * 2002-05-01 2004-04-22 Massachusetts Institute Of Technology Microfermentors for rapid screening and analysis of biochemical processes

Also Published As

Publication number Publication date
CA2491896A1 (en) 2004-01-15
AU2003246931A1 (en) 2004-01-23
GB0215879D0 (en) 2002-08-14
EP1535064B1 (de) 2007-08-29
WO2004005922A2 (en) 2004-01-15
AU2003246931B2 (en) 2007-01-25
US20060051733A1 (en) 2006-03-09
ATE371867T1 (de) 2007-09-15
EP1535064A2 (de) 2005-06-01
DE60315992T2 (de) 2008-01-24
WO2004005922A3 (en) 2004-03-11
JP2005532060A (ja) 2005-10-27

Similar Documents

Publication Publication Date Title
ATE371867T1 (de) Überwachung von zellen
NO20042954L (no) Fremgangsmate for detektering i grunt vann
DE60042578D1 (de) Vorrichtung zur elektrochemischen Erzeugung von Sauerstoff
PL375900A1 (en) Dosage forms containing a proton pump inhibitor, a nsaid, and a buffer
DK1255126T3 (da) Fremgangsmåde til at lette overvagningen af udviklingen over tiden af fysiske tilstande i en underjordisk formation
TW200510832A (en) Display unit using interferometric modulation and manufacturing method thereof
DK1343215T3 (da) Struktureret legeme til en i brændselsceller anvendt anode
TW200603531A (en) Method of forming a self-gated transistor and structure therefor
DE60207304D1 (de) Elektrosimulationsvorrichtung für benutzer von transportmitteln
DE60330632D1 (de) Vorrichtung zur Überwachung des Herzens
DE60301801D1 (de) Elektrochemischer Sensor zum Nachweis von Kohlenmonoxid
DE50213056D1 (de) Sensoranordnung, vorrichtung und verfahren zur ampologischen wirkort- und/oder wirkstofftestung
DK1963941T3 (da) Robotsystem
WO2004102150A3 (en) Electrode comprising material to help stabilize oxide of catalyst for electrochemical sensor
WO2007092331A3 (en) Detection methods and devices
TW200608007A (en) Method and apparatus for monitoring detergent concentration in a decontamination process
WO2003081253A3 (en) Electrochemical multi-well plate
FI20020565A7 (fi) Kennorakenne, laite ja menetelmä
ATE544092T1 (de) Elektrochemische vorrichtung
NO20024048D0 (no) Fremgangsmåte for drift av en elektrolysecelle samt midler for samme
WO2002074924A3 (en) Method for measuring serine palmitoyltransferase in mammalian tissue and use thereof
DE10256898A8 (de) Elektrochemischer Nachweis von Nukleinsäuren
DE50105612D1 (de) Vorrichtung zur elektrischen energieversorgung von meldern, steuer- und signalisierungseinrichtungen
EP1536807A4 (de) NICHTPOLYMERE HûMATOPOETISCHE ZELLGERINNSEL F R DIE ABGABE VON WIRKSTOFFEN
EP1263614A4 (de) Sicherheitsdokument oder vorrichtung mit kontrasttiefdruckeffekt

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee