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DE60314904D1 - Verfahren zur herstellung von chinoloncarboxylat-derivaten - Google Patents

Verfahren zur herstellung von chinoloncarboxylat-derivaten

Info

Publication number
DE60314904D1
DE60314904D1 DE60314904T DE60314904T DE60314904D1 DE 60314904 D1 DE60314904 D1 DE 60314904D1 DE 60314904 T DE60314904 T DE 60314904T DE 60314904 T DE60314904 T DE 60314904T DE 60314904 D1 DE60314904 D1 DE 60314904D1
Authority
DE
Germany
Prior art keywords
chinoloncarboxylate
derivatives
preparation
preparing
high yield
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60314904T
Other languages
English (en)
Other versions
DE60314904T2 (de
Inventor
Tai-Au Lee
Nam-Jin Park
Ja-Heouk Khoo
Seong-Ho Song
Ju-Young An
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yuhan Corp
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of DE60314904D1 publication Critical patent/DE60314904D1/de
Application granted granted Critical
Publication of DE60314904T2 publication Critical patent/DE60314904T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE60314904T 2002-12-21 2003-12-19 Verfahren zur herstellung von chinoloncarboxylat-derivaten Expired - Lifetime DE60314904T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2002-0082222A KR100519158B1 (ko) 2002-12-21 2002-12-21 퀴놀론 카르복실레이트 유도체의 제조방법
KR2002082222 2002-12-21
PCT/KR2003/002785 WO2004056781A1 (en) 2002-12-21 2003-12-19 Processes for preparing quinolonecarboxylate derivatives

Publications (2)

Publication Number Publication Date
DE60314904D1 true DE60314904D1 (de) 2007-08-23
DE60314904T2 DE60314904T2 (de) 2008-03-13

Family

ID=36383808

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60314904T Expired - Lifetime DE60314904T2 (de) 2002-12-21 2003-12-19 Verfahren zur herstellung von chinoloncarboxylat-derivaten

Country Status (10)

Country Link
US (1) US7220861B2 (de)
EP (1) EP1572657B1 (de)
JP (1) JP4310278B2 (de)
KR (1) KR100519158B1 (de)
AT (1) ATE366723T1 (de)
AU (1) AU2003286968A1 (de)
CA (1) CA2508341C (de)
DE (1) DE60314904T2 (de)
ES (1) ES2286483T3 (de)
WO (1) WO2004056781A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2150544B1 (de) 2007-03-19 2016-01-13 Takeda Pharmaceutical Company Limited Mapk/erk kinase inhibitoren
CN103864682B (zh) * 2012-12-18 2016-12-28 上海迪赛诺化学制药有限公司 一种制备iii型埃替拉韦晶体的方法
CN104151241B (zh) * 2013-05-15 2018-04-10 上海迪赛诺化学制药有限公司 一种iv型埃替拉韦晶体及其制备方法
CN110194738B (zh) * 2019-06-03 2022-04-05 华侨大学 一种1,2,3-三取代4-喹诺酮衍生物的制备方法
CN110283168B (zh) * 2019-06-06 2021-05-28 赤峰万泽药业股份有限公司 一种甲苯磺酸妥舒沙星环合物的合成方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4730000A (en) 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
DE3420798A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
DE3441788A1 (de) * 1984-11-15 1986-05-15 Bayer Ag, 5090 Leverkusen Alkyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
AU594983B2 (en) 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
US5237060A (en) 1985-12-10 1993-08-17 Bayer Aktiengesellschaft Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
DE3600891A1 (de) 1986-01-15 1987-07-16 Bayer Ag 1,8-verbrueckte 4-chinolon-3-carbonsaeuren und diese enthaltende arzneimittel
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
US4777253A (en) 1986-04-25 1988-10-11 Abbott Laboratories Process for preparation of racemate and optically active ofloxacin and related derivatives
JPH01100165A (ja) 1987-10-13 1989-04-18 Shionogi & Co Ltd オキシムまたはヒドロキシアミン誘導体系抗菌剤
US5407932A (en) * 1989-03-31 1995-04-18 Wakunaga Seiyaku Kabushiki Kaisha Quinolone derivatives and antibacterial agents containing the same
DE4015299A1 (de) * 1990-05-12 1991-11-14 Bayer Ag Verfahren zur herstellung von 3-amino-2-(het)-aroyl-acrylsaeurederivaten
US5869661A (en) 1991-07-16 1999-02-09 Chugai Seiyaku Kabushiki Kaisha Method of producing a quinolonecarboxylic acid derivative
DE4342186A1 (de) 1993-12-10 1995-06-14 Bayer Ag Eintopfverfahren zur Herstellung von 3-Chinoloncarbonsäurederivaten
KR100309871B1 (ko) * 1999-02-24 2001-10-29 윤종용 (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법
DE19826050A1 (de) * 1998-06-12 1999-12-16 Bayer Ag Verfahren zur Herstellung von Chinolon- und Naphthyridoncarbonsäuren und deren Ester
CN1338455A (zh) * 2000-08-16 2002-03-06 大连绿源实业有限公司 新的喹诺酮羧酸的制备方法
DE10108750A1 (de) * 2001-02-23 2002-09-05 Bayer Ag Verbessertes Verfahren zur Herstellung von Fluorchinoloncarbonsäuren

Also Published As

Publication number Publication date
KR100519158B1 (ko) 2005-10-06
KR20040055527A (ko) 2004-06-26
US20060058528A1 (en) 2006-03-16
JP2006514033A (ja) 2006-04-27
CA2508341A1 (en) 2004-07-08
AU2003286968A1 (en) 2004-07-14
ES2286483T3 (es) 2007-12-01
EP1572657A4 (de) 2006-03-01
JP4310278B2 (ja) 2009-08-05
DE60314904T2 (de) 2008-03-13
EP1572657A1 (de) 2005-09-14
US7220861B2 (en) 2007-05-22
EP1572657B1 (de) 2007-07-11
WO2004056781A1 (en) 2004-07-08
CA2508341C (en) 2011-10-18
ATE366723T1 (de) 2007-08-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition