DE60310944D1 - Weitere neue formen von interferierende rns moleküle - Google Patents
Weitere neue formen von interferierende rns moleküleInfo
- Publication number
- DE60310944D1 DE60310944D1 DE60310944T DE60310944T DE60310944D1 DE 60310944 D1 DE60310944 D1 DE 60310944D1 DE 60310944 T DE60310944 T DE 60310944T DE 60310944 T DE60310944 T DE 60310944T DE 60310944 D1 DE60310944 D1 DE 60310944D1
- Authority
- DE
- Germany
- Prior art keywords
- molecules
- stretch
- new forms
- strand
- stranded structure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
- C12Y207/11001—Non-specific serine/threonine protein kinase (2.7.11.1), i.e. casein kinase or checkpoint kinase
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- C12Y301/00—Hydrolases acting on ester bonds (3.1)
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- C12N2310/13—Decoys
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/321—2'-O-R Modification
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- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/343—Spatial arrangement of the modifications having patterns, e.g. ==--==--==--
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- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/346—Spatial arrangement of the modifications having a combination of backbone and sugar modifications
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- C12N2310/3521—Methyl
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- C12N2310/3525—MOE, methoxyethoxy
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- C12N2310/531—Stem-loop; Hairpin
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Immunology (AREA)
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Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02017601A EP1389637B1 (de) | 2002-08-05 | 2002-08-05 | Interferierende RNS Moleküle mit glatten Enden |
| EP02017601 | 2002-08-05 | ||
| US40254102P | 2002-08-12 | 2002-08-12 | |
| US402541P | 2002-08-12 | ||
| EP03008383 | 2003-04-10 | ||
| EP03008383 | 2003-04-10 | ||
| EP03784183.0A EP1527176B2 (de) | 2002-08-05 | 2003-08-05 | Weitere neue formen von interferierende rns moleküle |
| PCT/EP2003/008666 WO2004015107A2 (en) | 2002-08-05 | 2003-08-05 | Further novel forms of interfering rna molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE60310944D1 true DE60310944D1 (de) | 2007-02-15 |
| DE60310944T2 DE60310944T2 (de) | 2007-10-11 |
| DE60310944T3 DE60310944T3 (de) | 2017-08-03 |
Family
ID=31720998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60310944.6T Expired - Lifetime DE60310944T3 (de) | 2002-08-05 | 2003-08-05 | Weitere neue formen von interferierende rns moleküle |
Country Status (19)
| Country | Link |
|---|---|
| US (15) | US7452987B2 (de) |
| EP (6) | EP1527176B2 (de) |
| JP (4) | JP5490655B2 (de) |
| KR (1) | KR101201664B1 (de) |
| CN (1) | CN100543137C (de) |
| AT (1) | ATE350473T2 (de) |
| AU (2) | AU2003260370B2 (de) |
| BR (1) | BRPI0313202A8 (de) |
| CA (1) | CA2494930C (de) |
| CY (4) | CY1106422T1 (de) |
| DE (1) | DE60310944T3 (de) |
| DK (4) | DK1857547T3 (de) |
| ES (1) | ES2280826T5 (de) |
| IL (2) | IL166546A0 (de) |
| MX (1) | MXPA05001355A (de) |
| PT (1) | PT1527176E (de) |
| SI (3) | SI3222724T1 (de) |
| WO (1) | WO2004015107A2 (de) |
| ZA (1) | ZA200500459B (de) |
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