DE60308836D1 - Ophthalmische zubereitung mit ascomycin - Google Patents
Ophthalmische zubereitung mit ascomycinInfo
- Publication number
- DE60308836D1 DE60308836D1 DE60308836T DE60308836T DE60308836D1 DE 60308836 D1 DE60308836 D1 DE 60308836D1 DE 60308836 T DE60308836 T DE 60308836T DE 60308836 T DE60308836 T DE 60308836T DE 60308836 D1 DE60308836 D1 DE 60308836D1
- Authority
- DE
- Germany
- Prior art keywords
- ascomycin
- ophthalmic preparation
- ophthalmic
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- ZDQSOHOQTUFQEM-PKUCKEGBSA-N ascomycin Chemical compound C/C([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@@H](OC)C[C@@H](C)C\C(C)=C/[C@H](C(C[C@H](O)[C@H]1C)=O)CC)=C\[C@@H]1CC[C@@H](O)[C@H](OC)C1 ZDQSOHOQTUFQEM-PKUCKEGBSA-N 0.000 title 1
- ZDQSOHOQTUFQEM-XCXYXIJFSA-N ascomycin Natural products CC[C@H]1C=C(C)C[C@@H](C)C[C@@H](OC)[C@H]2O[C@@](O)([C@@H](C)C[C@H]2OC)C(=O)C(=O)N3CCCC[C@@H]3C(=O)O[C@H]([C@H](C)[C@@H](O)CC1=O)C(=C[C@@H]4CC[C@@H](O)[C@H](C4)OC)C ZDQSOHOQTUFQEM-XCXYXIJFSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36151502P | 2002-03-04 | 2002-03-04 | |
| US361515P | 2002-03-04 | ||
| US40927502P | 2002-09-09 | 2002-09-09 | |
| US409275P | 2002-09-09 | ||
| PCT/EP2003/002156 WO2003074054A1 (en) | 2002-03-04 | 2003-03-03 | Ophthalmic composition comprising ascomycin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60308836D1 true DE60308836D1 (de) | 2006-11-16 |
| DE60308836T2 DE60308836T2 (de) | 2007-04-26 |
Family
ID=27791682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60308836T Expired - Lifetime DE60308836T2 (de) | 2002-03-04 | 2003-03-03 | Ophthalmische zubereitung mit ascomycin |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US20050220823A1 (de) |
| EP (1) | EP1482936B1 (de) |
| JP (1) | JP4740542B2 (de) |
| KR (1) | KR100992948B1 (de) |
| CN (1) | CN1297270C (de) |
| AR (1) | AR038628A1 (de) |
| AT (1) | ATE341326T1 (de) |
| AU (1) | AU2003218679B2 (de) |
| BR (1) | BR0308184A (de) |
| CA (1) | CA2477769C (de) |
| CO (1) | CO5611133A2 (de) |
| DE (1) | DE60308836T2 (de) |
| DK (1) | DK1482936T3 (de) |
| EC (1) | ECSP045277A (de) |
| EG (1) | EG24403A (de) |
| ES (1) | ES2274214T3 (de) |
| IL (2) | IL163657A0 (de) |
| MX (1) | MXPA04008571A (de) |
| MY (1) | MY137563A (de) |
| NO (1) | NO20044092L (de) |
| NZ (1) | NZ534690A (de) |
| PE (1) | PE20030828A1 (de) |
| PL (1) | PL210870B1 (de) |
| PT (1) | PT1482936E (de) |
| RU (1) | RU2322982C2 (de) |
| TW (1) | TW200305437A (de) |
| WO (1) | WO2003074054A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4463681B2 (ja) | 2002-07-15 | 2010-05-19 | アルコン,インコーポレイテッド | 眼内使用のための非ポリマー親油性薬学的インプラント組成物 |
| EP2319493A3 (de) * | 2002-07-23 | 2011-07-27 | Novartis AG | Ophthalmische Salbenzusammensetzung , einen Wirkstoff, eine Salbengrundlage und eine Löslichkeits-/Dispergierbarkeitsvermittler enthaltend |
| GB0307866D0 (en) * | 2003-04-04 | 2003-05-14 | Novartis Ag | Pharmaceutical composition |
| BRPI0705564B8 (pt) * | 2007-10-10 | 2021-05-25 | Embrapa Pesquisa Agropecuaria | sistema do tipo cristal líquido contínuo contendo co-solvente portador de substâncias fracamente solúveis em água, seu processo de obtenção e seus usos |
| EP2238878A1 (de) | 2009-04-09 | 2010-10-13 | Nestec S.A. | Getränkezubereitungsvorrichtung mit einem Verschlussmechanismus mit Mitteln zur starken Abnahme der Kraft |
| US8728516B2 (en) * | 2009-04-30 | 2014-05-20 | Abbvie Inc. | Stabilized lipid formulation of apoptosis promoter |
| EP2962688B1 (de) * | 2009-05-12 | 2020-06-24 | Galenica AB | Öl-in-wasser emulsion enthaltend mometason und propylenglycol |
| RU2550956C2 (ru) * | 2009-12-22 | 2015-05-20 | Эббви Инк. | Капсула авт-263 |
| RU2437647C2 (ru) * | 2010-02-27 | 2011-12-27 | Пшеничников Виталий Георгиевич | Фармацевтическая композиция, обладающая антибактериальным, противовирусным и противогрибковым действием |
| EP2555748A2 (de) * | 2010-04-07 | 2013-02-13 | Allergan, Inc. | Konservierungsstoffkombinationen für ophthalmische zusammensetzungen |
| EP2664329A1 (de) * | 2012-05-15 | 2013-11-20 | F. Holzer GmbH | Ophthalmologisches Vehikelsystem |
| CN105431138B (zh) * | 2013-03-27 | 2019-01-11 | 全球药物科技有限公司 | 眼药组合物、其制备方法及用途 |
| WO2015080249A1 (ja) * | 2013-11-29 | 2015-06-04 | ロート製薬株式会社 | 眼科用又は耳鼻科用水性組成物 |
| US20200237859A1 (en) | 2019-01-25 | 2020-07-30 | Newport Research, Inc. | Aqueous suspensions of cyclosporin |
| US11324800B2 (en) | 2015-01-15 | 2022-05-10 | Wellspring Ophthalmics, Inc. | Aqueous suspensions of cyclosporin |
| US10606760B2 (en) * | 2017-08-23 | 2020-03-31 | Samsung Electronics Co., Ltd. | Nonvolatile memory devices and methods of controlling the same |
| EP3741367A1 (de) * | 2019-05-21 | 2020-11-25 | Premark Pharma GmbH | Behandlung von augenerkrankungen |
| TW202432089A (zh) * | 2023-01-31 | 2024-08-16 | 溫士頓醫藥股份有限公司 | 一種滴眼油劑型的醫藥組合物 |
| EP4687895A1 (de) | 2023-04-06 | 2026-02-11 | Premark Pharma GmbH | Verwendung von pimecrolimus zur behandlung des trockenen auges bei patienten mit einem hornhautfärbungswert von 4 oder 5 auf der oxford-abstufung |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0406791B1 (de) * | 1989-07-05 | 1995-02-01 | Fujisawa Pharmaceutical Co., Ltd. | Wässriges flüssiges Mittel zur äusserlichen Anwendung |
| EP0474126B1 (de) * | 1990-09-04 | 1997-03-19 | Fujisawa Pharmaceutical Co., Ltd. | Tricyclische Verbindungen enthaltende Salben |
| PH31204A (en) * | 1990-11-02 | 1998-05-05 | Fujisawa Pharmaceutical Co | Pharmaceutical composition. |
| IE65341B1 (en) * | 1990-11-08 | 1995-10-18 | Fujisawa Pharmaceutical Co | Suspensions containing tricyclic compounds |
| WO1994005298A1 (en) * | 1992-08-28 | 1994-03-17 | Pharmos Corporation | Submicron emulsions as ocular drug delivery vehicles |
| JPH06345646A (ja) * | 1993-06-08 | 1994-12-20 | Fujisawa Pharmaceut Co Ltd | ローション剤 |
| AU680539B2 (en) * | 1993-08-18 | 1997-07-31 | Alcon Laboratories, Inc. | Use of ergoline derivatives for the treatment of glaucoma |
| CA2201134A1 (en) * | 1994-10-10 | 1996-04-18 | Alfred Sallmann | Ophthalmic and aural compositions containing diclofenac potassium |
| DE69525957T2 (de) * | 1994-10-26 | 2002-11-14 | Novartis Ag | Verwendung eines ungesättigten Fettalkohols |
| EP0737471A3 (de) * | 1995-04-10 | 2000-12-06 | L'oreal | Verwendung von Erdalkalimetallsalze als TNF-alpha Inhibitor in einer topischen Zusammensetzung und die so hergestellte Zusammensetzung |
| FR2732598B1 (fr) * | 1995-04-10 | 1997-05-09 | Oreal | Utilisation de sel de metaux alcalino-terreux pour le traitement des prurits et des dysesthesies oculaires ou palpebraux |
| US6096785A (en) * | 1996-07-30 | 2000-08-01 | Novartis Nutrition Ag | Amino acid compositions and use thereof in treating renal dysfunction |
| FR2755852B1 (fr) * | 1996-11-15 | 1998-12-24 | Oreal | Utilisation d'un alkylether de glycerol dans une composition cosmetique et/ou dermatologique comme actif pour le traitement de la seborrhee et de l'acne |
| JP3732525B2 (ja) * | 1998-04-27 | 2006-01-05 | アステラス製薬株式会社 | 医薬組成物 |
| GB9826656D0 (en) * | 1998-12-03 | 1999-01-27 | Novartis Ag | Organic compounds |
| MXPA01010988A (es) * | 1999-04-30 | 2004-04-21 | Sucampo Ag | Uso de un compuesto macrolido para el tratamiento del ojo seco. |
-
2003
- 2003-02-28 PE PE2003000198A patent/PE20030828A1/es not_active Application Discontinuation
- 2003-02-28 AR ARP030100667A patent/AR038628A1/es unknown
- 2003-03-02 EG EG2003030208A patent/EG24403A/xx active
- 2003-03-03 KR KR1020047013051A patent/KR100992948B1/ko not_active Expired - Fee Related
- 2003-03-03 JP JP2003572571A patent/JP4740542B2/ja not_active Expired - Fee Related
- 2003-03-03 DK DK03711914T patent/DK1482936T3/da active
- 2003-03-03 WO PCT/EP2003/002156 patent/WO2003074054A1/en not_active Ceased
- 2003-03-03 DE DE60308836T patent/DE60308836T2/de not_active Expired - Lifetime
- 2003-03-03 CA CA2477769A patent/CA2477769C/en not_active Expired - Fee Related
- 2003-03-03 BR BR0308184-2A patent/BR0308184A/pt not_active IP Right Cessation
- 2003-03-03 PL PL370917A patent/PL210870B1/pl not_active IP Right Cessation
- 2003-03-03 TW TW092104405A patent/TW200305437A/zh unknown
- 2003-03-03 AT AT03711914T patent/ATE341326T1/de active
- 2003-03-03 MX MXPA04008571A patent/MXPA04008571A/es active IP Right Grant
- 2003-03-03 PT PT03711914T patent/PT1482936E/pt unknown
- 2003-03-03 ES ES03711914T patent/ES2274214T3/es not_active Expired - Lifetime
- 2003-03-03 CN CNB038052105A patent/CN1297270C/zh not_active Expired - Fee Related
- 2003-03-03 US US10/506,233 patent/US20050220823A1/en not_active Abandoned
- 2003-03-03 NZ NZ534690A patent/NZ534690A/en not_active IP Right Cessation
- 2003-03-03 MY MYPI20030758A patent/MY137563A/en unknown
- 2003-03-03 RU RU2004129593/15A patent/RU2322982C2/ru not_active IP Right Cessation
- 2003-03-03 IL IL16365703A patent/IL163657A0/xx unknown
- 2003-03-03 EP EP03711914A patent/EP1482936B1/de not_active Expired - Lifetime
- 2003-03-03 AU AU2003218679A patent/AU2003218679B2/en not_active Ceased
-
2004
- 2004-08-19 IL IL163657A patent/IL163657A/en not_active IP Right Cessation
- 2004-09-03 EC EC2004005277A patent/ECSP045277A/es unknown
- 2004-09-16 CO CO04092300A patent/CO5611133A2/es not_active Application Discontinuation
- 2004-09-27 NO NO20044092A patent/NO20044092L/no not_active Application Discontinuation
-
2009
- 2009-12-15 US US12/638,313 patent/US20100113501A1/en not_active Abandoned
-
2011
- 2011-03-01 US US13/037,399 patent/US20110152307A1/en not_active Abandoned
- 2011-09-23 US US13/241,340 patent/US20120015971A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |