DE60235900D1 - Osuppressivum - Google Patents
OsuppressivumInfo
- Publication number
- DE60235900D1 DE60235900D1 DE60235900T DE60235900T DE60235900D1 DE 60235900 D1 DE60235900 D1 DE 60235900D1 DE 60235900 T DE60235900 T DE 60235900T DE 60235900 T DE60235900 T DE 60235900T DE 60235900 D1 DE60235900 D1 DE 60235900D1
- Authority
- DE
- Germany
- Prior art keywords
- present
- derivatives
- diaryl
- osuppressivum
- benzyloxyphenoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Otolaryngology (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Ophthalmology & Optometry (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Cephalosporin Compounds (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001297400 | 2001-09-27 | ||
| JP2002216191 | 2002-07-25 | ||
| PCT/JP2002/009864 WO2003029184A1 (en) | 2001-09-27 | 2002-09-25 | Diaryl ether derivative, addition salt thereof, and immunosuppressant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60235900D1 true DE60235900D1 (de) | 2010-05-20 |
Family
ID=26623110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60235900T Expired - Lifetime DE60235900D1 (de) | 2001-09-27 | 2002-09-25 | Osuppressivum |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6963012B2 (de) |
| EP (1) | EP1431275B1 (de) |
| JP (1) | JP4152884B2 (de) |
| AT (1) | ATE463478T1 (de) |
| CA (1) | CA2460640C (de) |
| DE (1) | DE60235900D1 (de) |
| WO (1) | WO2003029184A1 (de) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0212894B8 (pt) * | 2001-09-27 | 2021-05-25 | Kyorin Seiyaku Kk | composto ou sal do mesmo farmaceuticamente aceitável e composição farmacêutica |
| EP1471054B1 (de) | 2002-01-11 | 2009-07-01 | Daiichi Sankyo Company, Limited | Aminoalkoholderivat oder phosphonsäurederivat und diese enthaltende medizinische zusammensetzung |
| KR20120125398A (ko) | 2002-05-16 | 2012-11-14 | 노파르티스 아게 | 암에서 ｅｄｇ 수용체 결합제의 용도 |
| KR101003877B1 (ko) | 2002-09-19 | 2010-12-30 | 교린 세이야꾸 가부시키 가이샤 | 아미노알코올 유도체와 그 부가염 및 면역 억제제 |
| KR101095807B1 (ko) | 2002-09-24 | 2011-12-21 | 노파르티스 아게 | 탈수초성 장애의 치료에 있어서의 스핑고신-1-포스페이트 수용체 아고니스트 |
| DE602004017847D1 (de) | 2003-04-08 | 2009-01-02 | Novartis Ag | Feste pharmazeutische darreichungsformen mit einem s1p rezeptoragonisten und einem zuckeralkohol |
| ATE547395T1 (de) * | 2003-04-30 | 2012-03-15 | Novartis Pharma Gmbh | Aminopropanol-derivate als modulatoren des sphingosin-1-phosphat-rezeptors |
| GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
| GB0324210D0 (en) | 2003-10-15 | 2003-11-19 | Novartis Ag | Organic compounds |
| GB0329498D0 (en) * | 2003-12-19 | 2004-01-28 | Novartis Ag | Organic compounds |
| TW200526548A (en) * | 2003-12-25 | 2005-08-16 | Sankyo Co | Ether derivatives |
| GB0500020D0 (en) | 2005-01-04 | 2005-02-09 | Novartis Ag | Organic compounds |
| KR20110136901A (ko) | 2004-02-24 | 2011-12-21 | 상꾜 가부시키가이샤 | 아미노 알코올 화합물 |
| WO2005105146A1 (en) | 2004-05-03 | 2005-11-10 | Novartis Ag | Combinations comprising a s1p receptor agonist and a jak3 kinase inhibitor |
| RU2396982C2 (ru) * | 2004-07-16 | 2010-08-20 | Киорин Фармасьютикал Ко., Лтд. | Эффективный способ использования лекарственных средств и способ предотвращения выраженности побочных эффектов |
| TW200611687A (en) * | 2004-07-29 | 2006-04-16 | Sankyo Co | Pharmaceutical compositions used for immunosuppressant |
| RU2402324C2 (ru) | 2004-07-30 | 2010-10-27 | Новартис Аг | Композиции на основе соединений 2-амино-1,3-пропандиола |
| ES2563034T3 (es) | 2004-10-12 | 2016-03-10 | Kyorin Pharmaceutical Co., Ltd. | Procedimiento para producir hidrocloruro de 2-amino-2-[2-[4-(3-benciloxifeniltio)-2-clorofenil]etil]-1,3-propanodiol e hidratos del mismo, e intermedios para la producción de los mismos |
| ES2495690T3 (es) * | 2004-11-29 | 2014-09-17 | Novartis Ag | Régimen de dosificación de un agonista del receptor S1P |
| GB0504544D0 (en) | 2005-03-04 | 2005-04-13 | Novartis Ag | Organic compounds |
| TWI418350B (zh) * | 2005-06-24 | 2013-12-11 | Sankyo Co | 含有ｐｐａｒ調節劑之醫藥組成物的用途 |
| AR057455A1 (es) * | 2005-07-22 | 2007-12-05 | Merck & Co Inc | Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica |
| GT200600350A (es) * | 2005-08-09 | 2007-03-28 | Formulaciones líquidas | |
| SG165364A1 (en) * | 2005-09-09 | 2010-10-28 | Novartis Ag | Treatment of autoimmune diseases |
| EP1932522B1 (de) * | 2005-10-07 | 2012-05-23 | Kyorin Pharmaceutical Co., Ltd. | Therapeutisches Mittel gegen Lebererkrankungen mit einem 2-Amino-1,3-propandiol-Derivat als Wirkstoff |
| TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| BRPI0710878A2 (pt) | 2006-04-11 | 2015-03-31 | Novartis Ag | Compostos orgânicos e seus usos |
| ES2491224T3 (es) | 2006-04-28 | 2014-09-05 | Mitsubishi Tanabe Pharma Corporation | Compuesto de 2-aminobutanol y su uso para fines médicos |
| TW200815600A (en) | 2006-08-04 | 2008-04-01 | Daiichi Sankyo Co Ltd | An enzyme for phosphorizing a medicine |
| JP5140593B2 (ja) | 2006-08-08 | 2013-02-06 | 杏林製薬株式会社 | アミノアルコール誘導体及びそれらを有効成分とする免疫抑制剤 |
| HRP20131172T1 (hr) * | 2006-08-08 | 2014-01-17 | Kyorin Pharmaceutical Co., Ltd. | Esterski derivat aminofosforne kiseline i modulator receptora s1p koji sadrži isti kao aktivni sastojak |
| BRPI0813683A2 (pt) * | 2007-06-14 | 2019-09-24 | Mitsubishi Tanabe Pharma Corp | composto amina e uso farmacêutico do mesmo |
| EP2465492B1 (de) | 2007-10-12 | 2015-07-01 | Novartis AG | Zusammensetzung mit Sphingosin-I-Phosphat (SIP)-Rezeptormodulatoren |
| US7816435B2 (en) * | 2007-10-31 | 2010-10-19 | Momentive Performance Materials Inc. | Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom |
| US8476305B2 (en) | 2008-02-07 | 2013-07-02 | Kyorin Pharmaceutical Co., Ltd. | Therapeutic agent or prophylactic agent for inflammatory bowel disease comprising amino alcohol derivative as active ingredient |
| DK2278960T4 (da) | 2008-03-17 | 2020-01-27 | Actelion Pharmaceuticals Ltd | Dosisregimen til en selektiv sip1 receptoragonist |
| CN103396346A (zh) * | 2008-05-19 | 2013-11-20 | 杏林制药株式会社 | 光学活性氨基醇衍生物的制备方法 |
| MY154685A (en) * | 2008-05-20 | 2015-07-15 | Kyorin Seiyaku Kk | Agent for maintanance of induced remission |
| GB0901835D0 (en) | 2009-02-04 | 2009-03-11 | Syngenta Ltd | Novel herbicides |
| GB0901834D0 (en) | 2009-02-04 | 2009-03-11 | Syngenta Ltd | Novel herbicides |
| US20110182850A1 (en) | 2009-04-10 | 2011-07-28 | Trixi Brandl | Organic compounds and their uses |
| US8512690B2 (en) | 2009-04-10 | 2013-08-20 | Novartis Ag | Derivatised proline containing peptide compounds as protease inhibitors |
| DK2452944T3 (da) | 2009-07-09 | 2014-10-27 | Kyorin Seiyaku Kk | Diphenylsulfidderivater samt lægemidler indeholdende dem som aktivt stof |
| KR101148098B1 (ko) | 2010-04-30 | 2012-05-22 | 한국화학연구원 | 1-［4-（4-니트로-페녹시）-페닐］-프로판-1-온을 유효성분으로 함유하는 톡소포자충 및 콕시디움에 기인한 질환의 예방 및 치료용 조성물 |
| MX2012012926A (es) | 2010-05-06 | 2012-12-17 | Novartis Ag | Tratamiento de enfermedades autoinmunes. |
| EA201201515A1 (ru) | 2010-05-06 | 2013-08-30 | Новартис Аг | Схема приема производных диарилсульфидов |
| AU2011311880B2 (en) | 2010-10-08 | 2014-07-24 | Novartis Ag | Vitamin E formulations of sulfamide NS3 inhibitors |
| TWI519539B (zh) | 2010-12-21 | 2016-02-01 | Kyorin Seiyaku Kk | Diphenyl sulfide derivatives and pharmaceuticals as an active ingredient thereof |
| CN102863345A (zh) * | 2011-07-06 | 2013-01-09 | 中国医学科学院药物研究所 | 胺基丙二醇类衍生物、其制备方法和其药物组合物与用途 |
| EA026736B1 (ru) | 2011-07-13 | 2017-05-31 | Басф Агро Б.В. | Фунгицидные замещенные 2-[2-галогеналкил-4-(фенокси)фенил]-1-[1,2,4]триазол-1-ил-этанольные соединения |
| US9137996B2 (en) | 2011-07-15 | 2015-09-22 | Basf Se | Fungicidal alkyl- and aryl-substituted 2[-2-chloro-4-(dihalo-phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds |
| EP2731438B1 (de) | 2011-07-15 | 2015-04-08 | Basf Se | Fungizide alkyl-substituierte 2-[2-chlor-4-(4-chlor-phenoxy)-phenyl]-1-[1,2,4]triazol-1 yl-ethanolverbindungen |
| EP2744794B1 (de) | 2011-08-15 | 2015-12-30 | Basf Se | Fungizide substituierte 1-{2-cyclyloxy-2-[2-halo-4-(4-halogen-phenoxy)-phenyl]-ethyl}-1h-[1,2,4]triazol-verbindungen |
| CA2842861A1 (en) | 2011-08-15 | 2013-02-21 | Basf Se | Fungicidal substituted 1-{2-[2-halo-4-(4-halogen-phenoxy)-phenyl]-2-alkoxy-2-alkynyl/alkenyl-ethyl}-1h-[1,2,4]triazole compounds |
| EP2744791B1 (de) | 2011-08-15 | 2015-10-28 | Basf Se | Fungizide substituierte 1-{2-[2-halo-4-(4-halogen-phenoxy-)phenyl-]2-alkoxy-3-methyl-butyl}-1h-[1,2,4-]triazol-verbindungen |
| JP6194306B2 (ja) | 2012-04-23 | 2017-09-06 | 田辺三菱製薬株式会社 | アミン化合物及びその医薬用途 |
| EP2934147B1 (de) | 2012-12-20 | 2019-11-27 | BASF Agro B.V. | Zusammensetzungen enthaltend eine triazol-verbindung |
| WO2014108286A1 (en) | 2013-01-09 | 2014-07-17 | Basf Se | Process for the preparation of substituted oxiranes and triazoles |
| CA2916777A1 (en) | 2013-07-08 | 2015-01-15 | BASF Agro B.V. | Compositions comprising a triazole compound and a biopesticide |
| CN104844486B (zh) * | 2014-02-17 | 2018-10-30 | 中国医学科学院药物研究所 | 胺基丙二醇类衍生物、其制备方法和其药物组合物与用途 |
| EA201892682A1 (ru) | 2014-06-25 | 2019-04-30 | Басф Агро Б.В. | Пестицидные композиции |
| EP3214937B1 (de) | 2014-11-07 | 2024-07-03 | Basf Se | Pestizidgemische |
| US11425909B2 (en) | 2016-03-16 | 2022-08-30 | Basf Se | Use of tetrazolinones for combating resistant phytopathogenic fungi on fruits |
| US11241012B2 (en) | 2016-03-16 | 2022-02-08 | Basf Se | Use of tetrazolinones for combating resistant phytopathogenic fungi on soybean |
| UA125210C2 (uk) | 2016-03-16 | 2022-02-02 | Басф Се | Застосування тетразолінонів для боротьби зі стійкими фітопатогенними грибами на злакових культурах |
| MX2021001039A (es) | 2018-07-27 | 2021-04-12 | Priothera Ltd | Preparacion para inhibir la reaparicion de una malignidad hematologica en pacientes quienes han pasado por trasplante de celulas madre hematopoyeticas. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0155015B1 (ko) * | 1992-10-21 | 1998-12-01 | 고우야 마사시 | 2-아미노-1,3-프로판디올 화합물 및 면역 억제제 |
| JP3870419B2 (ja) * | 1994-08-22 | 2007-01-17 | 三菱ウェルファーマ株式会社 | ベンゼン化合物およびその医薬としての用途 |
| AU735853B2 (en) | 1997-04-04 | 2001-07-19 | Mitsubishi Pharma Corporation | 2-aminopropane-1,3-diol compound, Pharmaceutical use thereof and synthetic intermediates therefor |
-
2002
- 2002-09-25 US US10/490,345 patent/US6963012B2/en not_active Expired - Fee Related
- 2002-09-25 WO PCT/JP2002/009864 patent/WO2003029184A1/ja not_active Ceased
- 2002-09-25 AT AT02768056T patent/ATE463478T1/de not_active IP Right Cessation
- 2002-09-25 CA CA2460640A patent/CA2460640C/en not_active Expired - Fee Related
- 2002-09-25 EP EP02768056A patent/EP1431275B1/de not_active Expired - Lifetime
- 2002-09-25 JP JP2003532439A patent/JP4152884B2/ja not_active Expired - Fee Related
- 2002-09-25 DE DE60235900T patent/DE60235900D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP4152884B2 (ja) | 2008-09-17 |
| CA2460640A1 (en) | 2003-04-10 |
| EP1431275A1 (de) | 2004-06-23 |
| ATE463478T1 (de) | 2010-04-15 |
| US20040242654A1 (en) | 2004-12-02 |
| EP1431275B1 (de) | 2010-04-07 |
| WO2003029184A1 (en) | 2003-04-10 |
| CA2460640C (en) | 2011-03-29 |
| JPWO2003029184A1 (ja) | 2005-01-13 |
| US6963012B2 (en) | 2005-11-08 |
| EP1431275A4 (de) | 2006-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |