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NO995963D0 - Karboksamider anvendelige som 5-HTIF-agonister - Google Patents

Karboksamider anvendelige som 5-HTIF-agonister

Info

Publication number
NO995963D0
NO995963D0 NO995963A NO995963A NO995963D0 NO 995963 D0 NO995963 D0 NO 995963D0 NO 995963 A NO995963 A NO 995963A NO 995963 A NO995963 A NO 995963A NO 995963 D0 NO995963 D0 NO 995963D0
Authority
NO
Norway
Prior art keywords
carboxamides
carboxamides useful
htif
agonists
htif agonists
Prior art date
Application number
NO995963A
Other languages
English (en)
Other versions
NO995963L (no
Inventor
Michael Edward Flaugh
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO995963L publication Critical patent/NO995963L/no
Publication of NO995963D0 publication Critical patent/NO995963D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyamides (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Organic Insulating Materials (AREA)
  • Conductive Materials (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Internal Circuitry In Semiconductor Integrated Circuit Devices (AREA)
  • Semiconductor Integrated Circuits (AREA)
NO995963A 1997-06-04 1999-12-03 Karboksamider anvendelige som 5-HTIF-agonister NO995963D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4858497P 1997-06-04 1997-06-04
PCT/US1998/003340 WO1998055115A1 (en) 1997-06-04 1998-06-01 Carboxamides useful as 5-ht1f agonists

Publications (2)

Publication Number Publication Date
NO995963L NO995963L (no) 1999-12-03
NO995963D0 true NO995963D0 (no) 1999-12-03

Family

ID=21955349

Family Applications (1)

Application Number Title Priority Date Filing Date
NO995963A NO995963D0 (no) 1997-06-04 1999-12-03 Karboksamider anvendelige som 5-HTIF-agonister

Country Status (21)

Country Link
EP (1) EP0882726B1 (no)
JP (1) JP2002502419A (no)
KR (1) KR20010013409A (no)
CN (1) CN1259049A (no)
AT (1) ATE240953T1 (no)
AU (1) AU729786B2 (no)
BR (1) BR9810610A (no)
CA (1) CA2291624A1 (no)
DE (1) DE69814735T2 (no)
DK (1) DK0882726T3 (no)
EA (1) EA001718B1 (no)
ES (1) ES2199410T3 (no)
HU (1) HUP0004142A3 (no)
ID (1) ID23053A (no)
IL (1) IL133279A0 (no)
NO (1) NO995963D0 (no)
NZ (1) NZ501569A (no)
PL (1) PL337221A1 (no)
PT (1) PT882726E (no)
TR (1) TR199903014T2 (no)
WO (1) WO1998055115A1 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1937300A (en) * 1998-12-11 2000-06-26 Eli Lilly And Company Indole derivatives and their use as 5-HT1F agonists
EP1184373A4 (en) 1999-04-20 2004-10-20 Meiji Seika Kaisha TRICYCLIC CONNECTIONS
US6495550B2 (en) 1999-08-04 2002-12-17 Icagen, Inc. Pyridine-substituted benzanilides as potassium ion channel openers
NZ527771A (en) * 1999-08-04 2005-04-29 Icagen Inc Methods for treating or preventing anxiety
DE60037321D1 (de) 1999-08-04 2008-01-17 Icagen Inc Benzanilide als öffner des kaliumkanals
TWI263497B (en) 2002-03-29 2006-10-11 Lilly Co Eli Pyridinoylpiperidines as 5-HT1F agonists
ES2388547T3 (es) 2003-04-18 2012-10-16 Eli Lilly And Company Compuestos de (piperidiniloxi)fenilo, (piperidiniloxi)piridinilo, (piperidinilsulfanil)fenilo y (piperidinilsulfanil)piridinilo como agonistas de 5-HT 1F
UA82711C2 (en) 2003-09-12 2008-05-12 Эли Лилли Энд Компани Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists
EP1697305B1 (en) * 2003-12-17 2007-08-15 Eli Lilly And Company Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-ht1f agonists
CA2617473A1 (en) 2005-08-08 2007-02-15 Astellas Pharma Inc. Acylguanidine derivative or salt thereof
KR20090114439A (ko) * 2007-02-07 2009-11-03 아스텔라스세이야쿠 가부시키가이샤 아실구아니딘 유도체
HUE037261T2 (hu) 2009-04-02 2018-08-28 Colucid Pharmaceuticals Inc 2,4,6-trifluor-N-[6-(1-metil-piperidin-4-karbonil)-piridin-2-il]-benzamid, migrén kezelésére orális vagy intravénás úton
DK2558447T3 (da) * 2010-03-22 2014-11-10 Actelion Pharmaceuticals Ltd 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazolderivater og deres anvendelse som prostaglandin d2-receptormodulatorer
WO2011123654A1 (en) 2010-04-02 2011-10-06 Colucid Pharmaceuticals, Inc. Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists
EP2983713A1 (en) * 2013-04-09 2016-02-17 Cresset Biomolecular Discovery Limited The treatment of inflammatory disorders
TWI826514B (zh) 2018-09-04 2023-12-21 美商美國禮來大藥廠 用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥
AR119319A1 (es) 2019-07-09 2021-12-09 Lilly Co Eli Procesos e intermediario para la preparación a gran escala de hemisuccinato de 2,4,6-trifluoro-n-[6-(1-metil-piperidina-4-carbonil)-piridin-2-il]-benzamida y preparación de acetato de 2,4,6-trifluoro-n-[6-(1-metil-piperidina-4-carbonil)-piridin-2-il]-benzamida
CN112125836A (zh) * 2020-10-15 2020-12-25 濮阳惠成电子材料股份有限公司 有机电致光电材料中间体n-苯基咔唑-3-羧酸乙酯的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9226566D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine
WO1996029075A1 (en) * 1995-03-20 1996-09-26 Eli Lilly And Company 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1h-indoles: new 5-ht1f agonists
CA2179678A1 (en) * 1995-06-23 1996-12-24 Michael Edward Flaugh 6-substituted-1,2,3,4-tetrahydro-9h-carbazoles and 7-substituted-10h-cyclohepta¬7,6-b| indoles

Also Published As

Publication number Publication date
EP0882726B1 (en) 2003-05-21
EA199901113A1 (ru) 2000-08-28
ID23053A (id) 2000-01-20
NO995963L (no) 1999-12-03
HUP0004142A2 (hu) 2001-05-28
DE69814735D1 (de) 2003-06-26
EP0882726A1 (en) 1998-12-09
ATE240953T1 (de) 2003-06-15
WO1998055115A1 (en) 1998-12-10
TR199903014T2 (xx) 2000-05-22
KR20010013409A (ko) 2001-02-26
NZ501569A (en) 2001-11-30
PL337221A1 (en) 2000-08-14
EA001718B1 (ru) 2001-08-27
BR9810610A (pt) 2000-09-12
IL133279A0 (en) 2001-04-30
JP2002502419A (ja) 2002-01-22
AU7795598A (en) 1998-12-21
AU729786B2 (en) 2001-02-08
DE69814735T2 (de) 2004-03-25
DK0882726T3 (da) 2003-09-22
CA2291624A1 (en) 1998-12-10
PT882726E (pt) 2003-09-30
HUP0004142A3 (en) 2002-10-28
CN1259049A (zh) 2000-07-05
ES2199410T3 (es) 2004-02-16

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