NO995963D0 - Karboksamider anvendelige som 5-HTIF-agonister - Google Patents
Karboksamider anvendelige som 5-HTIF-agonisterInfo
- Publication number
- NO995963D0 NO995963D0 NO995963A NO995963A NO995963D0 NO 995963 D0 NO995963 D0 NO 995963D0 NO 995963 A NO995963 A NO 995963A NO 995963 A NO995963 A NO 995963A NO 995963 D0 NO995963 D0 NO 995963D0
- Authority
- NO
- Norway
- Prior art keywords
- carboxamides
- carboxamides useful
- htif
- agonists
- htif agonists
- Prior art date
Links
- 239000000556 agonist Substances 0.000 title 1
- 150000003857 carboxamides Chemical class 0.000 title 1
- GZJDNSCLZKOHHP-UHFFFAOYSA-N 7-amino-6,7,8,9-tetrahydro-5h-carbazole-3-carboxamide Chemical class N1C2=CC=C(C(N)=O)C=C2C2=C1CC(N)CC2 GZJDNSCLZKOHHP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polyamides (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Organic Insulating Materials (AREA)
- Conductive Materials (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Internal Circuitry In Semiconductor Integrated Circuit Devices (AREA)
- Semiconductor Integrated Circuits (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4858497P | 1997-06-04 | 1997-06-04 | |
| PCT/US1998/003340 WO1998055115A1 (en) | 1997-06-04 | 1998-06-01 | Carboxamides useful as 5-ht1f agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO995963L NO995963L (no) | 1999-12-03 |
| NO995963D0 true NO995963D0 (no) | 1999-12-03 |
Family
ID=21955349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO995963A NO995963D0 (no) | 1997-06-04 | 1999-12-03 | Karboksamider anvendelige som 5-HTIF-agonister |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0882726B1 (no) |
| JP (1) | JP2002502419A (no) |
| KR (1) | KR20010013409A (no) |
| CN (1) | CN1259049A (no) |
| AT (1) | ATE240953T1 (no) |
| AU (1) | AU729786B2 (no) |
| BR (1) | BR9810610A (no) |
| CA (1) | CA2291624A1 (no) |
| DE (1) | DE69814735T2 (no) |
| DK (1) | DK0882726T3 (no) |
| EA (1) | EA001718B1 (no) |
| ES (1) | ES2199410T3 (no) |
| HU (1) | HUP0004142A3 (no) |
| ID (1) | ID23053A (no) |
| IL (1) | IL133279A0 (no) |
| NO (1) | NO995963D0 (no) |
| NZ (1) | NZ501569A (no) |
| PL (1) | PL337221A1 (no) |
| PT (1) | PT882726E (no) |
| TR (1) | TR199903014T2 (no) |
| WO (1) | WO1998055115A1 (no) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1937300A (en) * | 1998-12-11 | 2000-06-26 | Eli Lilly And Company | Indole derivatives and their use as 5-HT1F agonists |
| EP1184373A4 (en) | 1999-04-20 | 2004-10-20 | Meiji Seika Kaisha | TRICYCLIC CONNECTIONS |
| US6495550B2 (en) | 1999-08-04 | 2002-12-17 | Icagen, Inc. | Pyridine-substituted benzanilides as potassium ion channel openers |
| NZ527771A (en) * | 1999-08-04 | 2005-04-29 | Icagen Inc | Methods for treating or preventing anxiety |
| DE60037321D1 (de) | 1999-08-04 | 2008-01-17 | Icagen Inc | Benzanilide als öffner des kaliumkanals |
| TWI263497B (en) | 2002-03-29 | 2006-10-11 | Lilly Co Eli | Pyridinoylpiperidines as 5-HT1F agonists |
| ES2388547T3 (es) | 2003-04-18 | 2012-10-16 | Eli Lilly And Company | Compuestos de (piperidiniloxi)fenilo, (piperidiniloxi)piridinilo, (piperidinilsulfanil)fenilo y (piperidinilsulfanil)piridinilo como agonistas de 5-HT 1F |
| UA82711C2 (en) | 2003-09-12 | 2008-05-12 | Эли Лилли Энд Компани | Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists |
| EP1697305B1 (en) * | 2003-12-17 | 2007-08-15 | Eli Lilly And Company | Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-ht1f agonists |
| CA2617473A1 (en) | 2005-08-08 | 2007-02-15 | Astellas Pharma Inc. | Acylguanidine derivative or salt thereof |
| KR20090114439A (ko) * | 2007-02-07 | 2009-11-03 | 아스텔라스세이야쿠 가부시키가이샤 | 아실구아니딘 유도체 |
| HUE037261T2 (hu) | 2009-04-02 | 2018-08-28 | Colucid Pharmaceuticals Inc | 2,4,6-trifluor-N-[6-(1-metil-piperidin-4-karbonil)-piridin-2-il]-benzamid, migrén kezelésére orális vagy intravénás úton |
| DK2558447T3 (da) * | 2010-03-22 | 2014-11-10 | Actelion Pharmaceuticals Ltd | 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazolderivater og deres anvendelse som prostaglandin d2-receptormodulatorer |
| WO2011123654A1 (en) | 2010-04-02 | 2011-10-06 | Colucid Pharmaceuticals, Inc. | Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists |
| EP2983713A1 (en) * | 2013-04-09 | 2016-02-17 | Cresset Biomolecular Discovery Limited | The treatment of inflammatory disorders |
| TWI826514B (zh) | 2018-09-04 | 2023-12-21 | 美商美國禮來大藥廠 | 用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥 |
| AR119319A1 (es) | 2019-07-09 | 2021-12-09 | Lilly Co Eli | Procesos e intermediario para la preparación a gran escala de hemisuccinato de 2,4,6-trifluoro-n-[6-(1-metil-piperidina-4-carbonil)-piridin-2-il]-benzamida y preparación de acetato de 2,4,6-trifluoro-n-[6-(1-metil-piperidina-4-carbonil)-piridin-2-il]-benzamida |
| CN112125836A (zh) * | 2020-10-15 | 2020-12-25 | 濮阳惠成电子材料股份有限公司 | 有机电致光电材料中间体n-苯基咔唑-3-羧酸乙酯的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9226566D0 (en) * | 1992-12-21 | 1993-02-17 | Smithkline Beecham Plc | Compounds |
| US5521196A (en) * | 1994-10-05 | 1996-05-28 | Eli Lilly And Company | 5-HT1F agonists for the treatment of migraine |
| WO1996029075A1 (en) * | 1995-03-20 | 1996-09-26 | Eli Lilly And Company | 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1h-indoles: new 5-ht1f agonists |
| CA2179678A1 (en) * | 1995-06-23 | 1996-12-24 | Michael Edward Flaugh | 6-substituted-1,2,3,4-tetrahydro-9h-carbazoles and 7-substituted-10h-cyclohepta¬7,6-b| indoles |
-
1998
- 1998-01-06 ID IDW991411A patent/ID23053A/id unknown
- 1998-06-01 WO PCT/US1998/003340 patent/WO1998055115A1/en not_active Ceased
- 1998-06-01 KR KR19997011410A patent/KR20010013409A/ko not_active Withdrawn
- 1998-06-01 PL PL98337221A patent/PL337221A1/xx unknown
- 1998-06-01 AU AU77955/98A patent/AU729786B2/en not_active Ceased
- 1998-06-01 CA CA002291624A patent/CA2291624A1/en not_active Abandoned
- 1998-06-01 JP JP50237299A patent/JP2002502419A/ja not_active Ceased
- 1998-06-01 BR BR9810610-4A patent/BR9810610A/pt not_active IP Right Cessation
- 1998-06-01 EA EA199901113A patent/EA001718B1/ru not_active IP Right Cessation
- 1998-06-01 HU HU0004142A patent/HUP0004142A3/hu unknown
- 1998-06-01 TR TR1999/03014T patent/TR199903014T2/xx unknown
- 1998-06-01 CN CN98805776A patent/CN1259049A/zh active Pending
- 1998-06-01 IL IL13327998A patent/IL133279A0/xx unknown
- 1998-06-01 NZ NZ501569A patent/NZ501569A/en unknown
- 1998-06-02 AT AT98304343T patent/ATE240953T1/de not_active IP Right Cessation
- 1998-06-02 ES ES98304343T patent/ES2199410T3/es not_active Expired - Lifetime
- 1998-06-02 EP EP98304343A patent/EP0882726B1/en not_active Expired - Lifetime
- 1998-06-02 DE DE69814735T patent/DE69814735T2/de not_active Expired - Fee Related
- 1998-06-02 DK DK98304343T patent/DK0882726T3/da active
- 1998-06-02 PT PT98304343T patent/PT882726E/pt unknown
-
1999
- 1999-12-03 NO NO995963A patent/NO995963D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0882726B1 (en) | 2003-05-21 |
| EA199901113A1 (ru) | 2000-08-28 |
| ID23053A (id) | 2000-01-20 |
| NO995963L (no) | 1999-12-03 |
| HUP0004142A2 (hu) | 2001-05-28 |
| DE69814735D1 (de) | 2003-06-26 |
| EP0882726A1 (en) | 1998-12-09 |
| ATE240953T1 (de) | 2003-06-15 |
| WO1998055115A1 (en) | 1998-12-10 |
| TR199903014T2 (xx) | 2000-05-22 |
| KR20010013409A (ko) | 2001-02-26 |
| NZ501569A (en) | 2001-11-30 |
| PL337221A1 (en) | 2000-08-14 |
| EA001718B1 (ru) | 2001-08-27 |
| BR9810610A (pt) | 2000-09-12 |
| IL133279A0 (en) | 2001-04-30 |
| JP2002502419A (ja) | 2002-01-22 |
| AU7795598A (en) | 1998-12-21 |
| AU729786B2 (en) | 2001-02-08 |
| DE69814735T2 (de) | 2004-03-25 |
| DK0882726T3 (da) | 2003-09-22 |
| CA2291624A1 (en) | 1998-12-10 |
| PT882726E (pt) | 2003-09-30 |
| HUP0004142A3 (en) | 2002-10-28 |
| CN1259049A (zh) | 2000-07-05 |
| ES2199410T3 (es) | 2004-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |